Novel Cartilage-derived Biomimetic Scaffold for Human Nucleus Pulposus Regeneration: a Promising Therapeutic Strategy for Symptomatic Degenerative Disc Diseases

• Published in: Orthopaedic surgery Vol. 5; no. 1; pp. 60 - 63
• Main Authors: Yang, Qiang, Zhao, Yan-hong, Xia, Qun, Xu, Bao-shan, Ma, Xin-long, Liu, Yue, Hu, Yong-cheng, Li, Hong-fa, Miao, Jun, Wang, Tao, Ma, Jian-xiong, Sun, Xiao-lei
• Format: Journal Article
• Language: English
• Published: Australia Blackwell Publishing Ltd 01.02.2013; John Wiley & Sons, Inc; John Wiley and Sons Inc
• Subjects: Adipose Tissue - metabolism; Cartilage - metabolism; Degenerative disc diseases; Humans; Intervertebral Disc Degeneration - therapy; Medical Hypotheses; Medical research; Nucleus pulposus; Stem cells; Stem Cells - metabolism; Tissue engineering; Tissue Engineering - methods; Tissue Scaffolds

Because current therapies have not always been successful and effective, the possibility of regenerating the nucleus pulposus (NP) through a tissue‐engineered construct offers a novel therapeutic possibility for symptomatic degenerative disc diseases (DDDs). However, more research is necessary to id...