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Keywords: 631/250/249/2510/257/1402; 692/699/249/2510/2511; Adalimumab - therapeutic use; Adult; Arthritis, Rheumatoid - drug therapy; Arthritis, Rheumatoid - immunology; Biological treatment; Biomedical and Life Sciences; Biomedicine; Biopsy; Colitis, Ulcerative - drug therapy; Colitis, Ulcerative - immunology; Crohn Disease - drug therapy; Crohn Disease - immunology; Crohn's disease; Female; Granuloma; Humans; Immunology; Infectious Diseases; Inflammatory bowel disease; Inflammatory bowel diseases; Inflammatory Bowel Diseases - drug therapy; Inflammatory Bowel Diseases - immunology; Inflammatory diseases; Interferon; Interferons - metabolism; Longitudinal Studies; Lymphocytes T; Male; Medical treatment; Monoclonal antibodies; Precision medicine; Remission; Remission (Medicine); Resource; Rheumatoid arthritis; Rheumatoid synovitis; Signal Transduction; Single-Cell Analysis; Spatial analysis; Transcriptome; Transcriptomes; Tumor necrosis factor; Tumor Necrosis Factor-alpha - antagonists & inhibitors; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-TNF; Tumors; Ulcerative colitis