Glucose-Specific Enzyme IIA of the Phosphoenolpyruvate:Carbohydrate Phosphotransferase System Modulates Chitin Signaling Pathways in Vibrio cholerae

• Published in: Journal of bacteriology Vol. 199; no. 18
• Main Authors: Yamamoto, Shouji, Ohnishi, Makoto
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 15.09.2017
• Subjects: Bacteria; Bacteriology; Carbohydrates; Chitin; Chitin - metabolism; Chitinase; DNA Transposable Elements; Gene expression; Gene Expression Regulation, Bacterial; Gene Regulatory Networks; Intracellular levels; Molecular biology; Mutagenesis, Insertional; Nutrient status; Phosphoenolpyruvate Sugar Phosphotransferase System - metabolism; Phosphorylation; Phosphotransferase; Ribonucleic acid; RNA; Signal Transduction; Transcription; Vibrio cholerae; Vibrio cholerae - genetics; Vibrio cholerae - metabolism; Waterborne diseases; chitin utilization; two-component regulatory systems; phosphoenolpyruvate:carbohydrate phosphotransferase system; Vibrio cholerae; natural competence; chitin

In Vibrio cholerae , the genes required for chitin utilization and natural competence are governed by the chitin-responsive two-component system (TCS) sensor kinase ChiS. In the classical TCS paradigm, a sensor kinase specifically phosphorylates a cognate response regulator to activate gene expressi...