Retinol binding protein 4 and type 2 diabetes: from insulin resistance to pancreatic β-cell function

• Published in: Endocrine Vol. 85; no. 3; pp. 1020 - 1034
• Main Authors: Fan, Jiahua, Hu, Jinxing
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.09.2024; Springer Nature B.V
• Subjects: Animals; Beta cells; Biomarkers; Biomarkers - blood; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - metabolism; Endocrinology; Gastrointestinal surgery; Humanities and Social Sciences; Humans; Insulin resistance; Insulin Resistance - physiology; Insulin-Secreting Cells - metabolism; Insulin-Secreting Cells - physiology; Internal Medicine; Medicine; Medicine & Public Health; multidisciplinary; Pancreas; Retinol-Binding Proteins, Plasma - metabolism; Review; Science; Therapeutic applications; Vitamin A; Type 2 diabetes; Pancreatic β-cell function; Insulin resistance; Retinol binding protein 4

Background and aim Retinol binding protein 4 (RBP4) is an adipokine that has been explored as a key biomarker of type 2 diabetes mellitus (T2DM) in recent years. Researchers have conducted a series of experiments to understand the interplay between RBP4 and T2DM, including its role in insulin resist...