Regional variations in patient selection and procedural characteristics for cryoballoon ablation of atrial fibrillation in the cryo global registry
Background Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely adopted, regional variations in standards of care have not been well characterized. Methods Patients with AF were enrolled in the Cr...
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| Published in | Journal of interventional cardiac electrophysiology Vol. 67; no. 3; pp. 493 - 501 |
|---|---|
| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Springer US
01.04.2024
Springer Nature B.V |
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| Online Access | Get full text |
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| Abstract | Background
Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely adopted, regional variations in standards of care have not been well characterized.
Methods
Patients with AF were enrolled in the Cryo Global Registry (NCT02752737) from May 2016 to Sept 2021 at 128 sites in 37 countries and treated with cryoballoon ablation according to local clinical practice. Baseline patient and procedural characteristics were summarized for 8 regions (Central Asia & Russia, East Asia, Europe, Middle East, North America, South Africa, South America, and Southeast Asia). Serious procedure-related adverse events (SAEs) were evaluated in a subset of patients with ≥ 7 days of follow-up.
Results
A total of 3,680 patients undergoing initial PVI for AF were included. Cryoballoon ablation was commonly performed in patients with paroxysmal AF. Mean age ranged from 47 ± 12 years in the Middle East to 64 ± 11 years in East Asia. Mean procedure time was ≤ 95 min in all regions. Average freeze duration ranged from 153 ± 41 s in Southeast Asia to 230 ± 29 s in Central Asia & Russia. Acute procedural success was ≥ 94.7% in all geographies. In 3,126 subjects with ≥ 7 days of follow-up, 122 procedure-related SAEs were reported in 111 patients (3.6%) and remained low in all regions. One procedure-related death was reported during data collection.
Conclusions
Despite regional variations in patient selection and procedural characteristics, PVI using cryoballoon ablation was performed with high acute success and short procedural times around the world.
Clinical trial registration
https://clinicaltrials.gov/ct2/show/NCT02752737
Graphical Abstract |
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| AbstractList | Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely adopted, regional variations in standards of care have not been well characterized.BACKGROUNDCryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely adopted, regional variations in standards of care have not been well characterized.Patients with AF were enrolled in the Cryo Global Registry (NCT02752737) from May 2016 to Sept 2021 at 128 sites in 37 countries and treated with cryoballoon ablation according to local clinical practice. Baseline patient and procedural characteristics were summarized for 8 regions (Central Asia & Russia, East Asia, Europe, Middle East, North America, South Africa, South America, and Southeast Asia). Serious procedure-related adverse events (SAEs) were evaluated in a subset of patients with ≥ 7 days of follow-up.METHODSPatients with AF were enrolled in the Cryo Global Registry (NCT02752737) from May 2016 to Sept 2021 at 128 sites in 37 countries and treated with cryoballoon ablation according to local clinical practice. Baseline patient and procedural characteristics were summarized for 8 regions (Central Asia & Russia, East Asia, Europe, Middle East, North America, South Africa, South America, and Southeast Asia). Serious procedure-related adverse events (SAEs) were evaluated in a subset of patients with ≥ 7 days of follow-up.A total of 3,680 patients undergoing initial PVI for AF were included. Cryoballoon ablation was commonly performed in patients with paroxysmal AF. Mean age ranged from 47 ± 12 years in the Middle East to 64 ± 11 years in East Asia. Mean procedure time was ≤ 95 min in all regions. Average freeze duration ranged from 153 ± 41 s in Southeast Asia to 230 ± 29 s in Central Asia & Russia. Acute procedural success was ≥ 94.7% in all geographies. In 3,126 subjects with ≥ 7 days of follow-up, 122 procedure-related SAEs were reported in 111 patients (3.6%) and remained low in all regions. One procedure-related death was reported during data collection.RESULTSA total of 3,680 patients undergoing initial PVI for AF were included. Cryoballoon ablation was commonly performed in patients with paroxysmal AF. Mean age ranged from 47 ± 12 years in the Middle East to 64 ± 11 years in East Asia. Mean procedure time was ≤ 95 min in all regions. Average freeze duration ranged from 153 ± 41 s in Southeast Asia to 230 ± 29 s in Central Asia & Russia. Acute procedural success was ≥ 94.7% in all geographies. In 3,126 subjects with ≥ 7 days of follow-up, 122 procedure-related SAEs were reported in 111 patients (3.6%) and remained low in all regions. One procedure-related death was reported during data collection.Despite regional variations in patient selection and procedural characteristics, PVI using cryoballoon ablation was performed with high acute success and short procedural times around the world.CONCLUSIONSDespite regional variations in patient selection and procedural characteristics, PVI using cryoballoon ablation was performed with high acute success and short procedural times around the world.https://clinicaltrials.gov/ct2/show/NCT02752737.CLINICAL TRIAL REGISTRATIONhttps://clinicaltrials.gov/ct2/show/NCT02752737. Background Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely adopted, regional variations in standards of care have not been well characterized.MethodsPatients with AF were enrolled in the Cryo Global Registry (NCT02752737) from May 2016 to Sept 2021 at 128 sites in 37 countries and treated with cryoballoon ablation according to local clinical practice. Baseline patient and procedural characteristics were summarized for 8 regions (Central Asia & Russia, East Asia, Europe, Middle East, North America, South Africa, South America, and Southeast Asia). Serious procedure-related adverse events (SAEs) were evaluated in a subset of patients with ≥ 7 days of follow-up.ResultsA total of 3,680 patients undergoing initial PVI for AF were included. Cryoballoon ablation was commonly performed in patients with paroxysmal AF. Mean age ranged from 47 ± 12 years in the Middle East to 64 ± 11 years in East Asia. Mean procedure time was ≤ 95 min in all regions. Average freeze duration ranged from 153 ± 41 s in Southeast Asia to 230 ± 29 s in Central Asia & Russia. Acute procedural success was ≥ 94.7% in all geographies. In 3,126 subjects with ≥ 7 days of follow-up, 122 procedure-related SAEs were reported in 111 patients (3.6%) and remained low in all regions. One procedure-related death was reported during data collection.ConclusionsDespite regional variations in patient selection and procedural characteristics, PVI using cryoballoon ablation was performed with high acute success and short procedural times around the world.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/NCT02752737 Background Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely adopted, regional variations in standards of care have not been well characterized. Methods Patients with AF were enrolled in the Cryo Global Registry (NCT02752737) from May 2016 to Sept 2021 at 128 sites in 37 countries and treated with cryoballoon ablation according to local clinical practice. Baseline patient and procedural characteristics were summarized for 8 regions (Central Asia & Russia, East Asia, Europe, Middle East, North America, South Africa, South America, and Southeast Asia). Serious procedure-related adverse events (SAEs) were evaluated in a subset of patients with ≥ 7 days of follow-up. Results A total of 3,680 patients undergoing initial PVI for AF were included. Cryoballoon ablation was commonly performed in patients with paroxysmal AF. Mean age ranged from 47 ± 12 years in the Middle East to 64 ± 11 years in East Asia. Mean procedure time was ≤ 95 min in all regions. Average freeze duration ranged from 153 ± 41 s in Southeast Asia to 230 ± 29 s in Central Asia & Russia. Acute procedural success was ≥ 94.7% in all geographies. In 3,126 subjects with ≥ 7 days of follow-up, 122 procedure-related SAEs were reported in 111 patients (3.6%) and remained low in all regions. One procedure-related death was reported during data collection. Conclusions Despite regional variations in patient selection and procedural characteristics, PVI using cryoballoon ablation was performed with high acute success and short procedural times around the world. Clinical trial registration https://clinicaltrials.gov/ct2/show/NCT02752737 Graphical Abstract Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely adopted, regional variations in standards of care have not been well characterized. Patients with AF were enrolled in the Cryo Global Registry (NCT02752737) from May 2016 to Sept 2021 at 128 sites in 37 countries and treated with cryoballoon ablation according to local clinical practice. Baseline patient and procedural characteristics were summarized for 8 regions (Central Asia & Russia, East Asia, Europe, Middle East, North America, South Africa, South America, and Southeast Asia). Serious procedure-related adverse events (SAEs) were evaluated in a subset of patients with ≥ 7 days of follow-up. A total of 3,680 patients undergoing initial PVI for AF were included. Cryoballoon ablation was commonly performed in patients with paroxysmal AF. Mean age ranged from 47 ± 12 years in the Middle East to 64 ± 11 years in East Asia. Mean procedure time was ≤ 95 min in all regions. Average freeze duration ranged from 153 ± 41 s in Southeast Asia to 230 ± 29 s in Central Asia & Russia. Acute procedural success was ≥ 94.7% in all geographies. In 3,126 subjects with ≥ 7 days of follow-up, 122 procedure-related SAEs were reported in 111 patients (3.6%) and remained low in all regions. One procedure-related death was reported during data collection. Despite regional variations in patient selection and procedural characteristics, PVI using cryoballoon ablation was performed with high acute success and short procedural times around the world. https://clinicaltrials.gov/ct2/show/NCT02752737. |
| Author | Scazzuso, Fernando Obidigbo, Valentine Al-Kandari, Fawzia Földesi, Csaba Kaczmarek, Krzysztof Chun, K. R. Julian Khelae, Surinder Kaur Ptaszyński, Paweł van Bragt, Kelly A. Okumura, Ken On, Young Keun |
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| Keywords | Registry Cryoballoon Atrial fibrillation Catheter ablation Real-world evidence |
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| References | MonnickendamGDe AsmundisCWhy the distribution matters: Using discrete event simulation to demonstrate the impact of the distribution of procedure times on hospital operating room utilisation and average procedure costOper Res Health Care201816202810.1016/j.orhc.2017.12.001 ProvidenciaRDefayePLambiasePDPavinDCebronJPHalimiFAnselmeFSrinivasanNAlbenqueJPBovedaSResults from a multicentre comparison of cryoballoon vs. radiofrequency ablation for paroxysmal atrial fibrillation: is cryoablation more reproducible?Europace.2017191485710.1093/europace/euw08027267554 CappatoRAliHSurveys and registries on catheter ablation of atrial fibrillation: fifteen years of historyCirc Arrhythm Electrophysiol.2021141e00807310.1161/CIRCEP.120.00807333441001 Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2021;42(40):4194. https://doi.org/10.1093/eurheartj/ehab648 Erratum for: Eur Heart J. 2021;42(5):373-498 CoulombeNPaulinJSuWImproved in vivo performance of second-generation cryoballoon for pulmonary vein isolationJ Cardiovasc Electrophysiol201324891992510.1111/jce.1215723672309 SuWWReddyVYBhasinKCryoballoon ablation of pulmonary veins for persistent atrial fibrillation: Results from the multicenter STOP Persistent AF trialHeart Rhythm202017111841184710.1016/j.hrthm.2020.06.02032590151 CalkinsHHindricksGCappatoR2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillationEuropace2018201e1e16010.1093/europace/eux27429016840 Ferrero-de-Loma-OsorioÁGarcía-FernándezACastillo-CastilloJTime-to-Effect-Based Dosing Strategy for Cryoballoon Ablation in Patients With Paroxysmal Atrial Fibrillation: Results of the plusONE Multicenter Randomized Controlled Noninferiority TrialCirc Arrhythm Electrophysiol.20171012e00531810.1161/CIRCEP.117.00531829247029 MichaelsenJParadeUBauerleHTwelve-month efficacy of second-generation cryoballoon ablation for atrial fibrillation performed at community hospitals: results of the German register on cryoballoon ablation in local hospitals (regional)J Interv Card Electrophysiol20236641742510.1007/s10840-022-01331-935962151 AryanaAKenigsbergDNKowalskiMVerification of a novel atrial fibrillation cryoablation dosing algorithm guided by time-to-pulmonary vein isolation: Results from the Cryo-DOSING Study (Cryoballoon-ablation DOSING Based on the Assessment of Time-to-Effect and Pulmonary Vein Isolation Guidance)Heart Rhythm20171491319132510.1016/j.hrthm.2017.06.02028625929 AndradeJGChampagneJDubucMCryoballoon or Radiofrequency Ablation for Atrial Fibrillation Assessed by Continuous Monitoring: A Randomized Clinical TrialCirculation2019140221779178810.1161/CIRCULATIONAHA.119.04262231630538 ManfrinMVerlatoRArenaGSecond versus fourth generation of cryoballoon catheters: The 1STOP real-world multicenter experiencePacing Clin Electrophysiol202245896897410.1111/pace.1449435417055 CappatoRCalkinsHChenSAWorldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillationCirculation20051111100110510.1161/01.CIR.0000157153.30978.6715723973 FriedmanDJHolmesDCurtisABProcedure characteristics and outcomes of atrial fibrillation ablation procedures using cryoballoon versus radiofrequency ablation: A report from the GWTG-AFIB registryJ Cardiovasc Electrophysiol202132224825910.1111/jce.1485833368764 HeegerCHSohnsCPottAPhrenic Nerve Injury During Cryoballoon-Based Pulmonary Vein Isolation: Results of the Worldwide YETI RegistryCirc Arrhythm Electrophysiol.2022151e0105161:CAS:528:DC%2BB38XhsFCmtr0%3D10.1161/CIRCEP.121.01051634962134 KnightBPNovakPGSangrigoliRLong-Term Outcomes After Ablation for Paroxysmal Atrial Fibrillation Using the Second-Generation Cryoballoon: Final Results From STOP AF Post-Approval StudyJACC Clin Electrophysiol20195330631410.1016/j.jacep.2018.11.00630898232 VelagićVde AsmundisCMugnaiGLearning curve using the second-generation cryoballoon ablationJ Cardiovasc Med (Hagerstown)201718751852710.2459/JCM.000000000000049328009640 ScholzELugenbielPSchweizerPAEfficacy, High Procedural Safety And Rapid Optimization Of Cryoballoon Atrial Fibrillation Ablation In The Hands Of A New OperatorJ Atr Fibrillation201685134110.4022/jafib.1341279094745089487 ChunKRStichMFürnkranzAIndividualized cryoballoon energy pulmonary vein isolation guided by real-time pulmonary vein recordings, the randomized ICE-T trialHeart Rhythm201714449550010.1016/j.hrthm.2016.12.01427956248 HoffmannEStraubeFWegscheiderKOutcomes of cryoballoon or radiofrequency ablation in symptomatic paroxysmal or persistent atrial fibrillationEuropace20192191313132410.1093/europace/euz155311998606735953 HeegerCHWissnerEWohlmuthPBonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a "bonus-freeze" and "no bonus-freeze" protocol using the second-generation cryoballoon for pulmonary vein isolationClin Res Cardiol2016105977478210.1007/s00392-016-0987-8270857224989001 TebbenjohannsJHöferCBergmannLShortening of freezing cycles provides equal outcome to standard ablation procedure using second-generation 28 mm cryoballoon after 15-month follow-upEuropace201618220621010.1093/europace/euv18926071236 ChunKRJOkumuraKScazzusoFSafety and efficacy of cryoballoon ablation for the treatment of paroxysmal and persistent AF in a real-world global setting: Results from the Cryo AF Global RegistryJ of Arrhythmia202137235636710.1002/joa3.12504 ZucchelliGChunKRJKhelaeSKImpact of first-line cryoablation for atrial fibrillation on healthcare utilization, arrhythmia disease burden and efficacy outcomes: real-world evidence from the Cryo Global RegistryJ Interv Card Electrophysiol20236671172210.1007/s10840-022-01388-636331681 KuckKHBrugadaJFürnkranzACryoballoon or Radiofrequency Ablation for Paroxysmal Atrial FibrillationN Engl J Med2016374232235224510.1056/NEJMoa160201427042964 MörtsellDArbeloEDagresNCryoballoon vs. radiofrequency ablation for atrial fibrillation: a study of outcome and safety based on the ESC-EHRA atrial fibrillation ablation long-term registry and the Swedish catheter ablation registryEuropace.201921458158910.1093/europace/euy23930376055 1582_CR1 R Cappato (1582_CR15) 2021; 14 KR Chun (1582_CR24) 2017; 14 A Aryana (1582_CR26) 2017; 14 J Tebbenjohanns (1582_CR23) 2016; 18 V Velagić (1582_CR6) 2017; 18 M Manfrin (1582_CR19) 2022; 45 JG Andrade (1582_CR3) 2019; 140 CH Heeger (1582_CR22) 2016; 105 BP Knight (1582_CR9) 2019; 5 Á Ferrero-de-Loma-Osorio (1582_CR25) 2017; 10 KRJ Chun (1582_CR13) 2021; 37 KH Kuck (1582_CR2) 2016; 374 G Monnickendam (1582_CR5) 2018; 16 N Coulombe (1582_CR21) 2013; 24 WW Su (1582_CR10) 2020; 17 E Hoffmann (1582_CR4) 2019; 21 R Cappato (1582_CR14) 2005; 111 D Mörtsell (1582_CR20) 2019; 21 H Calkins (1582_CR12) 2018; 20 E Scholz (1582_CR7) 2016; 8 R Providencia (1582_CR8) 2017; 19 G Zucchelli (1582_CR16) 2023; 66 DJ Friedman (1582_CR11) 2021; 32 CH Heeger (1582_CR18) 2022; 15 J Michaelsen (1582_CR17) 2023; 66 |
| References_xml | – reference: ManfrinMVerlatoRArenaGSecond versus fourth generation of cryoballoon catheters: The 1STOP real-world multicenter experiencePacing Clin Electrophysiol202245896897410.1111/pace.1449435417055 – reference: TebbenjohannsJHöferCBergmannLShortening of freezing cycles provides equal outcome to standard ablation procedure using second-generation 28 mm cryoballoon after 15-month follow-upEuropace201618220621010.1093/europace/euv18926071236 – reference: FriedmanDJHolmesDCurtisABProcedure characteristics and outcomes of atrial fibrillation ablation procedures using cryoballoon versus radiofrequency ablation: A report from the GWTG-AFIB registryJ Cardiovasc Electrophysiol202132224825910.1111/jce.1485833368764 – reference: ChunKRStichMFürnkranzAIndividualized cryoballoon energy pulmonary vein isolation guided by real-time pulmonary vein recordings, the randomized ICE-T trialHeart Rhythm201714449550010.1016/j.hrthm.2016.12.01427956248 – reference: ZucchelliGChunKRJKhelaeSKImpact of first-line cryoablation for atrial fibrillation on healthcare utilization, arrhythmia disease burden and efficacy outcomes: real-world evidence from the Cryo Global RegistryJ Interv Card Electrophysiol20236671172210.1007/s10840-022-01388-636331681 – reference: Ferrero-de-Loma-OsorioÁGarcía-FernándezACastillo-CastilloJTime-to-Effect-Based Dosing Strategy for Cryoballoon Ablation in Patients With Paroxysmal Atrial Fibrillation: Results of the plusONE Multicenter Randomized Controlled Noninferiority TrialCirc Arrhythm Electrophysiol.20171012e00531810.1161/CIRCEP.117.00531829247029 – reference: ProvidenciaRDefayePLambiasePDPavinDCebronJPHalimiFAnselmeFSrinivasanNAlbenqueJPBovedaSResults from a multicentre comparison of cryoballoon vs. radiofrequency ablation for paroxysmal atrial fibrillation: is cryoablation more reproducible?Europace.2017191485710.1093/europace/euw08027267554 – reference: ScholzELugenbielPSchweizerPAEfficacy, High Procedural Safety And Rapid Optimization Of Cryoballoon Atrial Fibrillation Ablation In The Hands Of A New OperatorJ Atr Fibrillation201685134110.4022/jafib.1341279094745089487 – reference: CalkinsHHindricksGCappatoR2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillationEuropace2018201e1e16010.1093/europace/eux27429016840 – reference: HoffmannEStraubeFWegscheiderKOutcomes of cryoballoon or radiofrequency ablation in symptomatic paroxysmal or persistent atrial fibrillationEuropace20192191313132410.1093/europace/euz155311998606735953 – reference: CappatoRAliHSurveys and registries on catheter ablation of atrial fibrillation: fifteen years of historyCirc Arrhythm Electrophysiol.2021141e00807310.1161/CIRCEP.120.00807333441001 – reference: MichaelsenJParadeUBauerleHTwelve-month efficacy of second-generation cryoballoon ablation for atrial fibrillation performed at community hospitals: results of the German register on cryoballoon ablation in local hospitals (regional)J Interv Card Electrophysiol20236641742510.1007/s10840-022-01331-935962151 – reference: AryanaAKenigsbergDNKowalskiMVerification of a novel atrial fibrillation cryoablation dosing algorithm guided by time-to-pulmonary vein isolation: Results from the Cryo-DOSING Study (Cryoballoon-ablation DOSING Based on the Assessment of Time-to-Effect and Pulmonary Vein Isolation Guidance)Heart Rhythm20171491319132510.1016/j.hrthm.2017.06.02028625929 – reference: CappatoRCalkinsHChenSAWorldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillationCirculation20051111100110510.1161/01.CIR.0000157153.30978.6715723973 – reference: SuWWReddyVYBhasinKCryoballoon ablation of pulmonary veins for persistent atrial fibrillation: Results from the multicenter STOP Persistent AF trialHeart Rhythm202017111841184710.1016/j.hrthm.2020.06.02032590151 – reference: MonnickendamGDe AsmundisCWhy the distribution matters: Using discrete event simulation to demonstrate the impact of the distribution of procedure times on hospital operating room utilisation and average procedure costOper Res Health Care201816202810.1016/j.orhc.2017.12.001 – reference: KnightBPNovakPGSangrigoliRLong-Term Outcomes After Ablation for Paroxysmal Atrial Fibrillation Using the Second-Generation Cryoballoon: Final Results From STOP AF Post-Approval StudyJACC Clin Electrophysiol20195330631410.1016/j.jacep.2018.11.00630898232 – reference: ChunKRJOkumuraKScazzusoFSafety and efficacy of cryoballoon ablation for the treatment of paroxysmal and persistent AF in a real-world global setting: Results from the Cryo AF Global RegistryJ of Arrhythmia202137235636710.1002/joa3.12504 – reference: HeegerCHWissnerEWohlmuthPBonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a "bonus-freeze" and "no bonus-freeze" protocol using the second-generation cryoballoon for pulmonary vein isolationClin Res Cardiol2016105977478210.1007/s00392-016-0987-8270857224989001 – reference: Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2021;42(40):4194. https://doi.org/10.1093/eurheartj/ehab648 Erratum for: Eur Heart J. 2021;42(5):373-498 – reference: AndradeJGChampagneJDubucMCryoballoon or Radiofrequency Ablation for Atrial Fibrillation Assessed by Continuous Monitoring: A Randomized Clinical TrialCirculation2019140221779178810.1161/CIRCULATIONAHA.119.04262231630538 – reference: KuckKHBrugadaJFürnkranzACryoballoon or Radiofrequency Ablation for Paroxysmal Atrial FibrillationN Engl J Med2016374232235224510.1056/NEJMoa160201427042964 – reference: HeegerCHSohnsCPottAPhrenic Nerve Injury During Cryoballoon-Based Pulmonary Vein Isolation: Results of the Worldwide YETI RegistryCirc Arrhythm Electrophysiol.2022151e0105161:CAS:528:DC%2BB38XhsFCmtr0%3D10.1161/CIRCEP.121.01051634962134 – reference: VelagićVde AsmundisCMugnaiGLearning curve using the second-generation cryoballoon ablationJ Cardiovasc Med (Hagerstown)201718751852710.2459/JCM.000000000000049328009640 – reference: CoulombeNPaulinJSuWImproved in vivo performance of second-generation cryoballoon for pulmonary vein isolationJ Cardiovasc Electrophysiol201324891992510.1111/jce.1215723672309 – reference: MörtsellDArbeloEDagresNCryoballoon vs. radiofrequency ablation for atrial fibrillation: a study of outcome and safety based on the ESC-EHRA atrial fibrillation ablation long-term registry and the Swedish catheter ablation registryEuropace.201921458158910.1093/europace/euy23930376055 – ident: 1582_CR1 doi: 10.1093/eurheartj/ehab648 – volume: 21 start-page: 1313 issue: 9 year: 2019 ident: 1582_CR4 publication-title: Europace doi: 10.1093/europace/euz155 – volume: 5 start-page: 306 issue: 3 year: 2019 ident: 1582_CR9 publication-title: JACC Clin Electrophysiol doi: 10.1016/j.jacep.2018.11.006 – volume: 14 start-page: e008073 issue: 1 year: 2021 ident: 1582_CR15 publication-title: Circ Arrhythm Electrophysiol. doi: 10.1161/CIRCEP.120.008073 – volume: 16 start-page: 20 year: 2018 ident: 1582_CR5 publication-title: Oper Res Health Care doi: 10.1016/j.orhc.2017.12.001 – volume: 37 start-page: 356 issue: 2 year: 2021 ident: 1582_CR13 publication-title: J of Arrhythmia doi: 10.1002/joa3.12504 – volume: 140 start-page: 1779 issue: 22 year: 2019 ident: 1582_CR3 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.119.042622 – volume: 45 start-page: 968 issue: 8 year: 2022 ident: 1582_CR19 publication-title: Pacing Clin Electrophysiol doi: 10.1111/pace.14494 – volume: 105 start-page: 774 issue: 9 year: 2016 ident: 1582_CR22 publication-title: Clin Res Cardiol doi: 10.1007/s00392-016-0987-8 – volume: 111 start-page: 1100 year: 2005 ident: 1582_CR14 publication-title: Circulation doi: 10.1161/01.CIR.0000157153.30978.67 – volume: 18 start-page: 518 issue: 7 year: 2017 ident: 1582_CR6 publication-title: J Cardiovasc Med (Hagerstown) doi: 10.2459/JCM.0000000000000493 – volume: 14 start-page: 495 issue: 4 year: 2017 ident: 1582_CR24 publication-title: Heart Rhythm doi: 10.1016/j.hrthm.2016.12.014 – volume: 24 start-page: 919 issue: 8 year: 2013 ident: 1582_CR21 publication-title: J Cardiovasc Electrophysiol doi: 10.1111/jce.12157 – volume: 66 start-page: 711 year: 2023 ident: 1582_CR16 publication-title: J Interv Card Electrophysiol doi: 10.1007/s10840-022-01388-6 – volume: 374 start-page: 2235 issue: 23 year: 2016 ident: 1582_CR2 publication-title: N Engl J Med doi: 10.1056/NEJMoa1602014 – volume: 15 start-page: e010516 issue: 1 year: 2022 ident: 1582_CR18 publication-title: Circ Arrhythm Electrophysiol. doi: 10.1161/CIRCEP.121.010516 – volume: 18 start-page: 206 issue: 2 year: 2016 ident: 1582_CR23 publication-title: Europace doi: 10.1093/europace/euv189 – volume: 19 start-page: 48 issue: 1 year: 2017 ident: 1582_CR8 publication-title: Europace. doi: 10.1093/europace/euw080 – volume: 8 start-page: 1341 issue: 5 year: 2016 ident: 1582_CR7 publication-title: J Atr Fibrillation doi: 10.4022/jafib.1341 – volume: 20 start-page: e1 issue: 1 year: 2018 ident: 1582_CR12 publication-title: Europace doi: 10.1093/europace/eux274 – volume: 21 start-page: 581 issue: 4 year: 2019 ident: 1582_CR20 publication-title: Europace. doi: 10.1093/europace/euy239 – volume: 66 start-page: 417 year: 2023 ident: 1582_CR17 publication-title: J Interv Card Electrophysiol doi: 10.1007/s10840-022-01331-9 – volume: 10 start-page: e005318 issue: 12 year: 2017 ident: 1582_CR25 publication-title: Circ Arrhythm Electrophysiol. doi: 10.1161/CIRCEP.117.005318 – volume: 14 start-page: 1319 issue: 9 year: 2017 ident: 1582_CR26 publication-title: Heart Rhythm doi: 10.1016/j.hrthm.2017.06.020 – volume: 32 start-page: 248 issue: 2 year: 2021 ident: 1582_CR11 publication-title: J Cardiovasc Electrophysiol doi: 10.1111/jce.14858 – volume: 17 start-page: 1841 issue: 11 year: 2020 ident: 1582_CR10 publication-title: Heart Rhythm doi: 10.1016/j.hrthm.2020.06.020 |
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Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF).... Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). Although widely... Background Cryoballoon ablation is a well-established anatomical approach for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF).... |
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| SubjectTerms | Ablation Cardiac arrhythmia Cardiology Data collection Fibrillation Medicine Medicine & Public Health Patients Regions Variation |
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| Title | Regional variations in patient selection and procedural characteristics for cryoballoon ablation of atrial fibrillation in the cryo global registry |
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