Appraisal of Chitosan-Coated Lipid Nano-Combination with Miltefosine and Albendazole in the Treatment of Murine Trichinellosis: Experimental Study with Evaluation of Immunological and Immunohistochemical Parameters

• Published in: Acta parasitologica Vol. 69; no. 1; pp. 929 - 950
• Main Authors: Ibrahim, Asmaa F., Selim, Sahar M., Shafey, Dalia A., Sweed, Dina M., Farag, Shaimaa A., Gouda, Marwa A.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.03.2024; Springer Nature B.V
• Subjects: Adults; Albendazole; Animal Systematics/Taxonomy/Biogeography; Biomedical and Life Sciences; Biomedicine; Caspase-3; Chitosan; Coating effects; Coatings; Ecology; Effectiveness; GATA-3 protein; Glutathione; Immunology; Inflammation; Larvae; Lipids; Medical Microbiology; Microbiology; Miltefosine; Original Paper; Parasitology; Reduction; Scanning electron microscopy; Serum levels; Subgroups; Trichinellosis; Miltefosine; Glutathione peroxidase 1 (GPX1); Trichinellosis; GATA3; Chitosan-coated nanostructured lipid carriers; Caspase-3

Purpose Resistance and adverse consequences of albendazole (ABZ) in treating trichinellosis urged demand for secure and effective new drugs. The current study aimed to assess the effect of chitosan-coated lipid nano-combination with albendazole and miltefosine (MFS) in treating experimental murine t...