Validation of a multiple marker test for early pregnancy outcome prediction

• Published in: Journal of assisted reproduction and genetics Vol. 40; no. 4; pp. 837 - 844
• Main Authors: Bollig, Kassie J., Senapati, Suneeta, Sammel, Mary D., Takacs, Peter, Robins, Jared C., Haisenleder, Daniel J., Barnhart, Kurt T.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2023; Springer Nature B.V
• Subjects: Accuracy; Activin; Assisted Reproduction Technologies; Biomarkers; Case-Control Studies; Chorionic Gonadotropin; Ectopic pregnancy; Female; Gestational age; Glycodelin; Gonadotropins; Gynecology; Human Genetics; Humans; Infant; Medicine; Medicine & Public Health; Metalloproteinase; Pituitary (anterior); Predictions; Pregnancy; Pregnancy complications; Pregnancy Outcome; Pregnancy Trimester, First; Progesterone; Reproducibility; Reproducibility of Results; Reproductive Medicine; Validation; Ectopic pregnancy; Biomarker

Purpose To validate the use of a multiple biomarker test panel for predicting first trimester pregnancy outcome in a multi-center cohort. Methods A case-control study of women presenting with pain and bleeding in early pregnancy at 5–10 weeks gestational age was performed at three academic centers....