Fan-Shaped Body Neurons Are Involved in "Period"-Dependent Regulation of Long-Term Courtship Memory in "Drosophila"

• Published in: Learning & memory (Cold Spring Harbor, N.Y.) Vol. 19; no. 12; pp. 571 - 574
• Main Authors: Sakai, Takaomi, Inami, Show, Sato, Shoma, Kitamoto, Toshihiro
• Format: Journal Article
• Language: English
• Published: United States Cold Spring Harbor Laboratory Press 01.12.2012
• Subjects: Animals; Animals, Genetically Modified; Brain; Brief Communication; Conditioning; Courtship; Drosophila; Drosophila Proteins - genetics; Drosophila Proteins - metabolism; Entomology; Female; Gene Expression Regulation - genetics; Genetics; Green Fluorescent Proteins - genetics; Green Fluorescent Proteins - metabolism; Long Term Memory; Male; Memory, Long-Term - physiology; Mushroom Bodies - cytology; Neurology; Neurons - physiology; Period Circadian Proteins - genetics; Period Circadian Proteins - metabolism; Sleep; Sleep - genetics; Synaptic Transmission - genetics; Time Factors; Transcription Factors - metabolism

In addition to its established function in the regulation of circadian rhythms, the "Drosophila" gene "period" ("per") also plays an important role in processing long-term memory (LTM). Here, we used courtship conditioning as a learning paradigm and revealed that (1) ov...