Deregulated DNA ADP-ribosylation impairs telomere replication - Wondisford, Anne R.; Lee, Junyeop; Lu, Robert; Schuller, Marion; Groslambert, Josephine; Bhargava, Ragini; Schamus-Haynes, Sandra; Cespedes, Leyneir C.; Opresko, Patricia L.; Pickett, Hilda A.; Min, Jaewon; Ahel, Ivan; et al. (Nature structural & molecular biology, 2024)
Keywords: 13/106; 14/32; 14/63; 38/1; 38/71; 631/337/103/560; 631/337/151; 631/337/458/2389; 631/80/103/560; 631/92/458/2389; Adenosine diphosphate; Adenosine Diphosphate Ribose - metabolism; ADP-Ribosylation; Animals; Biochemistry; Biological Microscopy; Biomedical and Life Sciences; Deoxyribonucleic acid; Deregulation; DNA; DNA - metabolism; DNA biosynthesis; DNA Replication; Epigenetics; Fragility; Genomes; Genomic Instability; Humans; Integrity; Life Sciences; Membrane Biology; Mice; Okazaki fragments; Poly (ADP-Ribose) Polymerase-1 - genetics; Poly (ADP-Ribose) Polymerase-1 - metabolism; Poly(ADP-ribose) polymerase; Protein Structure; Replication; Ribose; Single-stranded DNA; Synthesis; Telomerase; Telomere - genetics; Telomere - metabolism; Telomere Shortening; Telomeres; Toxins