Preparation of Graphene/ITO Nanorod Metamaterial/U-Bent-Annealing Fiber Sensor and DNA Biomolecule Detection

In this paper, a graphene/ITO nanorod metamaterial/U-bent-annealing (Gr/ITO-NM/U-bent-A)-based U-bent optical fiber local surface plasmon resonance (LSPR) sensor is presented and demonstrated for DNA detection. The proposed sensor, compared with other conventional sensors, exhibits higher sensitivit...

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Published inNanomaterials (Basel, Switzerland) Vol. 9; no. 8; p. 1154
Main Authors Yang, Wen, Yu, Jing, Xi, Xiangtai, Sun, Yang, Shen, Yiming, Yue, Weiwei, Zhang, Chao, Jiang, Shouzhen
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 12.08.2019
MDPI
Subjects
Alcohol
Alcohols
Annealing
Biological properties
Biomolecules
Biosensors
Caustic soda
Deoxyribonucleic acid
DNA
Glucose
Graphene
high sensitivity
Hybridization
Indium
Indium tin oxides
ITO metamaterials
Laboratories
localized surface plasmon resonance biosensor
Metamaterials
Nanoparticles
Nanorods
Optical fibers
Oxides
Pharmaceuticals
Resonance
Sensor arrays
Sensors
Sodium
specificity deteection
Surface plasmon resonance
U-bent fiber
China
ITO metamaterials
high sensitivity
specificity deteection
localized surface plasmon resonance biosensor
U-bent fiber
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Summary:In this paper, a graphene/ITO nanorod metamaterial/U-bent-annealing (Gr/ITO-NM/U-bent-A)-based U-bent optical fiber local surface plasmon resonance (LSPR) sensor is presented and demonstrated for DNA detection. The proposed sensor, compared with other conventional sensors, exhibits higher sensitivity, lower cost, as well as better biological affinity and oxidize resistance. Besides, it has a structure of an original Indium Tin Oxides (ITO) nanocolumn array coated with graphene, allowing the sensor to exert significant bulk plasmon resonance effect. Moreover, for its discontinuous structure, a larger specific surface area is created to accommodate more biomolecules, thus maximizing the biological properties. The fabricated sensors exhibit great performance (690.7 nm/RIU) in alcohol solution testing. Furthermore, it also exhibits an excellent linear response (R2 = 0.998) to the target DNA with respective concentrations from 0.1 to 100 nM suggesting the promising medical applications of such sensors.
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ISSN:2079-4991
2079-4991
DOI:10.3390/nano9081154