Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer - Rojas, Luis A.; Sethna, Zachary; Soares, Kevin C.; Olcese, Cristina; Pang, Nan; Patterson, Erin; Lihm, Jayon; Ceglia, Nicholas; Guasp, Pablo; Chu, Alexander; Yu, Rebecca; Chandra, Adrienne Kaya; et al. (Nature (London), 2023)
Keywords: 13/31; 14/63; 38/39; 38/91; 45/23; 5-Fluorouracil; 631/67/1059/2325; 631/67/1504/1713; Adenocarcinoma; Adjuvants, Immunologic - therapeutic use; Antigens; Antigens, Neoplasm - immunology; Cancer therapies; Cancer Vaccines - immunology; Carcinoma, Pancreatic Ductal - genetics; Carcinoma, Pancreatic Ductal - immunology; Carcinoma, Pancreatic Ductal - therapy; CD8 antigen; CD8-Positive T-Lymphocytes - cytology; CD8-Positive T-Lymphocytes - immunology; Chemotherapy; Effector cells; Folinic acid; Humanities and Social Sciences; Humans; Immunotherapy; Irinotecan; Lymphocyte Activation - immunology; Lymphocytes; Lymphocytes T; Monoclonal antibodies; mRNA; mRNA Vaccines; multidisciplinary; Mutation; Nanoparticles; Neoantigens; Oxaliplatin; Pancreatic cancer; Pancreatic Neoplasms - genetics; Pancreatic Neoplasms - immunology; Pancreatic Neoplasms - therapy; Patients; Science; Science (multidisciplinary); Severe acute respiratory syndrome coronavirus 2; Surgery; Survival; T cell receptors; T-Lymphocytes - cytology; T-Lymphocytes - immunology; Targeted cancer therapy; Tumors; Uridine; Vaccines