Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases

• Published in: Kidney international Vol. 59; no. 6; pp. 2023 - 2038
• Main Authors: Matsumoto, Kunio, Nakamura, Toshikazu
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.06.2001; Nature Publishing; Elsevier Limited
• Subjects: acute renal failure; Biological and medical sciences; cell regeneration; chronic renal failure; Hepatocyte Growth Factor - therapeutic use; Humans; Kidney - physiology; Kidney Diseases - drug therapy; Kidney Diseases - physiopathology; Medical sciences; morphogenesis; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Regeneration - drug effects; Renal failure; renal fibrosis; acute renal failure; morphogenesis; renal fibrosis; chronic renal failure; cell regeneration; Kidney disease; Human; Urinary system disease; Renal function; Pathophysiology; Hepatocyte growth factor; Renal failure; Exploration; Growth factor
• ISSN: 0085-2538; 1523-1755
• DOI: 10.1046/j.1523-1755.2001.00717.x

Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases. Hepatocyte growth factor (HGF), a ligand for the c-Met receptor tyrosine kinase, has mitogenic, motogenic, anti-apoptotic, and morphogenic (for example, induction of branching tubulogenesis) activities for renal...