Anabolic steroids in part reverse glucocorticoid-induced alterations in rat diaphragm

• Published in: Journal of applied physiology (1985) Vol. 84; no. 5; pp. 1492 - 1499
• Main Authors: Van Balkom, Roland H. H, Dekhuijzen, P. N. Richard, Folgering, Hans T. M, Veerkamp, Jacques H, Van Moerkerk, Herman T, Fransen, Jack A. M, Van Herwaarden, Cees L. A
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Am Physiological Soc 01.05.1998; American Physiological Society
• Subjects: 3-Hydroxyacyl CoA Dehydrogenases - analysis; Anabolic Agents - pharmacology; Animals; Biological and medical sciences; Body Weight - drug effects; Citrate (si)-Synthase - analysis; Diaphragm - drug effects; Diaphragm - enzymology; Drug toxicity and drugs side effects treatment; Fatty Acids - metabolism; Glucocorticoids - pharmacology; Glycogen - metabolism; Male; Medical sciences; Methylprednisolone - pharmacology; Muscle Contraction - drug effects; Muscle Fibers, Skeletal - classification; Muscle Fibers, Skeletal - drug effects; Myosin Heavy Chains - classification; Nandrolone - analogs & derivatives; Nandrolone - pharmacology; Pharmacology. Drug treatments; Phosphorylases - analysis; Rats; Rats, Wistar; Respiration - drug effects; Toxicity: respiratory system, ent, stomatology; Steroid; Animal model; Rat; Respiratory disease; Toxicity; Low dose; Rodentia; Contractility; Methylprednisolone; Glucocorticoid; Long term; Vertebrata; Chemotherapy; Mammalia; Treatment; Respiratory muscle; Animal; Myosin; Diaphragm; Anabolic agent

1  Department of Pulmonary Diseases, University Hospital Nijmegen, and Departments of 2  Biochemistry and of 3  Cell Biology and Histology, University of Nijmegen, 6500 HB Nijmegen, The Netherlands Animal and clinical studies have shown respiratory muscle dysfunction caused by treatment with glucoco...