Conjunction of factors triggering waves of seasonal influenza

• Published in: eLife Vol. 7
• Main Authors: Chattopadhyay, Ishanu, Kiciman, Emre, Elliott, Joshua W, Shaman, Jeffrey L, Rzhetsky, Andrey
• Format: Journal Article
• Language: English
• Published: England eLife Sciences Publications Ltd 27.02.2018; eLife Sciences Publications, Ltd
• Subjects: Accounting; Air travel; Antigenic drift; Behavior; Causality; Disease Transmission, Infectious; Epidemiology and Global Health; Granger causality; Gravitational waves; Gravity; Humans; Humidity; Incidence; Infections; Infectious diseases; Influenza; Influenza, Human - epidemiology; Influenza, Human - transmission; Insurance claims; Longitudinal Studies; matching analysis; Mortality; Orthomyxoviridae - genetics; Orthomyxoviridae - immunology; Phase transitions; poisson regression; Public health; Seasons; Solar radiation; Spatio-Temporal Analysis; Travel; US influenza epidemic; Weather; United Kingdom > UK; United States > US; Chicago Illinois; global health; US influenza epidemic; epidemiology; poisson regression; human; virus; Granger causality; matching analysis
• ISSN: 2050-084X; 2050-084X
• DOI: 10.7554/eLife.30756

Using several longitudinal datasets describing putative factors affecting influenza incidence and clinical data on the disease and health status of over 150 million human subjects observed over a decade, we investigated the source and the mechanistic triggers of influenza epidemics. We conclude that...