Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation
The first checkpoint during T cell development, known as beta selection, requires the successful rearrangement of the TCR-beta gene locus. Notch signaling has been implicated in various stages during T lymphopoiesis. However, it is unclear whether Notch receptor-ligand interactions are necessary dur...
Saved in:
Published in | The Journal of immunology (1950) Vol. 172; no. 9; pp. 5230 - 5239 |
---|---|
Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Am Assoc Immnol
01.05.2004
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!