Sleep restores an optimal computational regime in cortical networks

• Published in: Nature neuroscience Vol. 27; no. 2; pp. 328 - 338
• Main Authors: Xu, Yifan, Schneider, Aidan, Wessel, Ralf, Hengen, Keith B.
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.02.2024; Nature Publishing Group
• Subjects: 631/378/116; 631/378/1385/519; 631/378/2613/1875; Animal Genetics and Genomics; Animals; Behavioral Sciences; Biological Techniques; Biomedical and Life Sciences; Biomedicine; Brain - physiology; Circuits; Computational neuroscience; Deviation; Electroencephalography - methods; Homeostasis - physiology; Neurobiology; Neurons; Neurosciences; Rats; Sleep; Sleep - physiology; Sleep and wakefulness; Visual cortex; Wakefulness - physiology

Sleep is assumed to subserve homeostatic processes in the brain; however, the set point around which sleep tunes circuit computations is unknown. Slow-wave activity (SWA) is commonly used to reflect the homeostatic aspect of sleep; although it can indicate sleep pressure, it does not explain why ani...