Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention

• Published in: International Journal of Obesity Vol. 47; no. 4; pp. 313 - 324
• Main Authors: Dreher, Simon I., Irmler, Martin, Pivovarova-Ramich, Olga, Kessler, Katharina, Jürchott, Karsten, Sticht, Carsten, Fritsche, Louise, Schneeweiss, Patrick, Machann, Jürgen, Pfeiffer, Andreas F. H., Hrabě de Angelis, Martin, Beckers, Johannes, Birkenfeld, Andreas L., Peter, Andreas, Niess, Andreas M., Weigert, Cora, Moller, Anja
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.04.2023; Nature Publishing Group
• Subjects: 13/105; 13/106; 38/39; 38/47; 38/56; 38/61; 38/77; 59/57; 631/80/642/333/1465; 692/163/2743/137/773; 692/308/575; 692/698/690/2816; 692/699/2743/2815; Adaptation; Adipose tissue; Adipose Tissue - metabolism; Adult; Biological clocks; Biopsy; Body fat; Body weight; Circadian rhythm; Circadian rhythms; Diabetes; Diabetes mellitus; Epidemiology; Exercise - physiology; Exercise Therapy; Female; Health Promotion and Disease Prevention; Humans; Internal Medicine; Lipid metabolism; Lipids; Lipogenesis; Male; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolic disorders; Metabolic syndrome; Metabolism; Mitochondria; Muscle, Skeletal - metabolism; Muscles; Musculoskeletal system; Obesity; Obesity - therapy; Overweight; Overweight - therapy; Prevention; Public Health; Reduction; Respiration; Respirometry; Skeletal muscle; Transcriptome; Transcriptomics; Treatment Outcome; Young Adult

Background Exercise exerts many health benefits by directly inducing molecular alterations in physically utilized skeletal muscle. Molecular adaptations of subcutaneous adipose tissue (SCAT) might also contribute to the prevention of metabolic diseases. Aim To characterize the response of human SCAT...