Utility of copeptin in predicting non-pathological postoperative polyuria in patients affected by acromegaly undergoing pituitary neurosurgery

• Published in: Pituitary Vol. 27; no. 5; pp. 488 - 496
• Main Authors: Varaldo, Emanuele, Prencipe, Nunzia, Berton, Alessandro Maria, Aversa, Luigi Simone, Bioletto, Fabio, De Marco, Raffaele, Gasco, Valentina, Zenga, Francesco, Grottoli, Silvia
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.10.2024; Springer Nature B.V
• Subjects: Acromegaly; Acromegaly - blood; Acromegaly - surgery; Adult; Aged; Diabetes insipidus; Diabetes Insipidus, Neurogenic - blood; Diabetes Insipidus, Neurogenic - etiology; Diuresis; Endocrinology; Female; Glycopeptides - blood; Growth hormones; Human Physiology; Humans; Hypothalamus; Male; Medicine; Medicine & Public Health; Middle Aged; Neurosurgery; Neurosurgical Procedures - adverse effects; Pituitary; Pituitary Gland - metabolism; Pituitary Gland - surgery; Polyuria; Polyuria - etiology; Postoperative Complications - blood; Prospective Studies; Remission; Central diabetes insipidus; GH; Fluid balance; Arginine vasopressin; Growth hormone; CT-proAVP

Purpose Copeptin efficiently predicts post-neurosurgical central diabetes insipidus (CDI) in patients with hypothalamic-pituitary lesions, but its role in characterizing changes in diuresis in individuals with acromegaly undergoing neurosurgery remains unexplored. Our study aimed to assess changes i...