Dendritiform immune cells with reduced antigen-capture capacity persist in the cornea during the asymptomatic phase of allergic conjunctivitis

• Published in: Eye (London) Vol. 37; no. 13; pp. 2768 - 2775
• Main Authors: Tajbakhsh, Zahra, Jalbert, Isabelle, Stapleton, Fiona, Alghamdi, Ali, Gray, Paul E., Briggs, Nancy, Altavilla, Betina, Mobeen, Rabia, Golebiowski, Blanka
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2023; Nature Publishing Group
• Subjects: 14; 14/19; 692/308/409; 692/699/3161; Antigens; Asymptomatic; Body size; Cell body; Cell morphology; Cell size; Confocal microscopy; Conjunctiva; Conjunctivitis; Cornea; Cytology; Dendrites; Dendritic cells; Hay fever; Laboratory Medicine; Medicine; Medicine & Public Health; Morphology; Ophthalmology; Pharmaceutical Sciences/Technology; Surgery; Surgical Oncology

Background Increased density and altered morphology of dendritic cells (DC) in the cornea and conjunctiva occur during active allergic conjunctivitis. This study investigated whether inflammation (characterised by altered DC density and morphology) persists during the symptom-free phase of allergic...