Role of perfusion SPECT in prediction and measurement of pulmonary complications after radiotherapy for lung cancer

• Published in: European journal of nuclear medicine and molecular imaging Vol. 42; no. 8; pp. 1315 - 1324
• Main Authors: Farr, Katherina P., Kramer, Stine, Khalil, Azza A., Morsing, Anni, Grau, Cai
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2015; Springer Nature B.V
• Subjects: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung - radiotherapy; Cardiology; Female; Humans; Imaging; Lung cancer; Lung Neoplasms - radiotherapy; Male; Medicine; Medicine & Public Health; Middle Aged; Nuclear Medicine; Oncology; Original Article; Orthopedics; Perfusion Imaging; Radiation Pneumonitis - diagnostic imaging; Radiation therapy; Radiology; Studies; Tomography, Emission-Computed, Single-Photon; Curative chemoradiotherapy; Non-small-cell lung cancer; Radiation-induced lung toxicity; Perfusion SPECT/CT; Radiation pneumonitis

Purpose The purpose of the study was to evaluate the ability of baseline perfusion defect score (DS) on SPECT to predict the development of severe symptomatic radiation pneumonitis (RP) and to evaluate changes in perfusion on SPECT as a method of lung perfusion function assessment after curative rad...