Complete sequence of mouse S6 ribosomal protein

• Published in: Nucleic acids research Vol. 15; no. 12; p. 4990
• Main Authors: LALANNE, J. L, LUCERO, M, LE MOULLEC, J.-M
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 25.06.1987
• Subjects: Amino Acid Sequence; Animals; Biological and medical sciences; cDNA; DNA - genetics; DNA, Recombinant; Fundamental and applied biological sciences. Psychology; Genes; Genes. Genome; Mice - genetics; Molecular and cellular biology; Molecular genetics; nucleotide sequence; Ribosomal Protein S6; Ribosomal Proteins - genetics; Vertebrata; Mammalia; Gene; Mouse; Animal; Rodentia; Primary structure; Ribosomal protein
• DOI: 10.1093/nar/15.12.4990
• ISSN: 0305-1048

The authors report the nucleotide (and deduced amino acid) sequence of mouse S6 ribosomal protein. This sequence was determined on both strands of full length cDNA clones isolated from a library made from T2D4 cells poly(A) + RNA. The protein was identified by computer analysis of NBRF data bank using CITI2 software due to its homology (60% overall) with yeast S10 ribosomal protein; it fits published partial amino acid sequences of rat S6, which cover respectively the NH2-terminus, and the sites of phosphorylation by cAMP-dependent protein kinases located at the COOH-terminus. Since S6 is a substrate for several kinases, this sequence could help to locate phosphorylated aminoc acids.