Clustering of KOR PET images separates people with AUD into distinct responses to naltrexone - Hoye, Jocelyn; Key, Jose; de Laat, Bart; Cosgrove, Kelly P.; Krishnan-Sarin, Suchitra; Papademetris, Xenophon; Morris, Evan D. (Brain imaging and behavior, 2023)
Keywords: Alcohol Drinking; Alcohol use; Alcoholism - diagnostic imaging; Alcoholism - drug therapy; Biomedical and Life Sciences; Biomedicine; Brief Report; Clustering; Drinking; Drinking behavior; Humans; Image acquisition; Magnetic Resonance Imaging; Naltrexone; Naltrexone - therapeutic use; Neostriatum; Neuropsychology; Neuroradiology; Neurosciences; Opioid receptors (type kappa); Positron emission; Positron-Emission Tomography - methods; Psychiatry; Receptors, Opioid, kappa; Reduction; Robustness; Sarin; Training; Variance analysis; Spectral clustering; Alcohol use disorder; Positron emission tomography; Small sample size; Machine learning; Kappa opioid receptor