Biometals and glycosylation in humans: Congenital disorders of glycosylation shed lights into the crucial role of Golgi manganese homeostasis

About half of the eukaryotic proteins bind biometals that participate in their structure and functions in virtually all physiological processes, including glycosylation. After reviewing the biological roles and transport mechanisms of calcium, magnesium, manganese, zinc and cobalt acting as cofactor...

Full description

Saved in:
Bibliographic Details
Published inBiochimica et biophysica acta. General subjects Vol. 1864; no. 10; p. 129674
Main Authors Foulquier, François, Legrand, Dominique
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.10.2020
Elsevier
Subjects
Animals
Antiporters - metabolism
Biochemistry, Molecular Biology
Biological Transport
Biometal homeostasis
calcium
Cation Transport Proteins - metabolism
cobalt
congenital abnormalities
Congenital disorders of glycosylation
Congenital Disorders of Glycosylation - metabolism
Congenital Disorders of Glycosylation - pathology
cytosol
extracellular space
Glycosylation
Golgi Apparatus - metabolism
Golgi Apparatus - pathology
Homeostasis
Humans
Life Sciences
magnesium
Manganese
Manganese - metabolism
metalloproteins
sugars
TMEM165
zinc
Glycosylation
Congenital disorders of glycosylation
Biometal homeostasis
Manganese
TMEM165
Online AccessGet full text

Cover

Abstract About half of the eukaryotic proteins bind biometals that participate in their structure and functions in virtually all physiological processes, including glycosylation. After reviewing the biological roles and transport mechanisms of calcium, magnesium, manganese, zinc and cobalt acting as cofactors of the metalloproteins involved in sugar metabolism and/or glycosylation, the paper will outline the pathologies resulting from a dysregulation of these metals homeostasis and more particularly Congenital Disorders of Glycosylation (CDGs) caused by ion transporter defects. Highlighting of CDGs due to defects in SLC39A8 (ZIP8) and TMEM165, two proteins transporting manganese from the extracellular space to cytosol and from cytosol to the Golgi lumen, respectively, has emphasized the importance of manganese homeostasis for glycosylation. Based on our current knowledge of TMEM165 structure and functions, this review will draw a picture of known and putative mechanisms regulating manganese homeostasis in the secretory pathway. •Panorama of biometals essential in glycosylation process.•Diseases resulting from disturbances in biometals homeostasis.•Link between Mn homeostasis and CDG.
AbstractList About half of the eukaryotic proteins bind biometals that participate in their structure and functions in virtually all physiological processes, including glycosylation. After reviewing the biological roles and transport mechanisms of calcium, magnesium, manganese, zinc and cobalt acting as cofactors of the metalloproteins involved in sugar metabolism and/or glycosylation, the paper will outline the pathologies resulting from a dysregulation of these metals homeostasis and more particularly Congenital Disorders of Glycosylation (CDGs) caused by ion transporter defects. Highlighting of CDGs due to defects in SLC39A8 (ZIP8) and TMEM165, two proteins transporting manganese from the extracellular space to cytosol and from cytosol to the Golgi lumen, respectively , has emphasized the importance of manganese homeostasis for glycosylation. Based on our current knowledge of TMEM165 structure and functions, this review will draw a picture of known and putative mechanisms regulating manganese homeostasis in the secretory pathway.
About half of the eukaryotic proteins bind biometals that participate in their structure and functions in virtually all physiological processes, including glycosylation. After reviewing the biological roles and transport mechanisms of calcium, magnesium, manganese, zinc and cobalt acting as cofactors of the metalloproteins involved in sugar metabolism and/or glycosylation, the paper will outline the pathologies resulting from a dysregulation of these metals homeostasis and more particularly Congenital Disorders of Glycosylation (CDGs) caused by ion transporter defects. Highlighting of CDGs due to defects in SLC39A8 (ZIP8) and TMEM165, two proteins transporting manganese from the extracellular space to cytosol and from cytosol to the Golgi lumen, respectively, has emphasized the importance of manganese homeostasis for glycosylation. Based on our current knowledge of TMEM165 structure and functions, this review will draw a picture of known and putative mechanisms regulating manganese homeostasis in the secretory pathway. •Panorama of biometals essential in glycosylation process.•Diseases resulting from disturbances in biometals homeostasis.•Link between Mn homeostasis and CDG.
About half of the eukaryotic proteins bind biometals that participate in their structure and functions in virtually all physiological processes, including glycosylation. After reviewing the biological roles and transport mechanisms of calcium, magnesium, manganese, zinc and cobalt acting as cofactors of the metalloproteins involved in sugar metabolism and/or glycosylation, the paper will outline the pathologies resulting from a dysregulation of these metals homeostasis and more particularly Congenital Disorders of Glycosylation (CDGs) caused by ion transporter defects. Highlighting of CDGs due to defects in SLC39A8 (ZIP8) and TMEM165, two proteins transporting manganese from the extracellular space to cytosol and from cytosol to the Golgi lumen, respectively, has emphasized the importance of manganese homeostasis for glycosylation. Based on our current knowledge of TMEM165 structure and functions, this review will draw a picture of known and putative mechanisms regulating manganese homeostasis in the secretory pathway.About half of the eukaryotic proteins bind biometals that participate in their structure and functions in virtually all physiological processes, including glycosylation. After reviewing the biological roles and transport mechanisms of calcium, magnesium, manganese, zinc and cobalt acting as cofactors of the metalloproteins involved in sugar metabolism and/or glycosylation, the paper will outline the pathologies resulting from a dysregulation of these metals homeostasis and more particularly Congenital Disorders of Glycosylation (CDGs) caused by ion transporter defects. Highlighting of CDGs due to defects in SLC39A8 (ZIP8) and TMEM165, two proteins transporting manganese from the extracellular space to cytosol and from cytosol to the Golgi lumen, respectively, has emphasized the importance of manganese homeostasis for glycosylation. Based on our current knowledge of TMEM165 structure and functions, this review will draw a picture of known and putative mechanisms regulating manganese homeostasis in the secretory pathway.
ArticleNumber 129674
Author Legrand, Dominique
Foulquier, François
Author_xml – sequence: 1
  givenname: François
  surname: Foulquier
  fullname: Foulquier, François
– sequence: 2
  givenname: Dominique
  surname: Legrand
  fullname: Legrand, Dominique
  email: dominique.legrand@univ-lille.fr
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32599014$$D View this record in MEDLINE/PubMed
https://hal.science/hal-02997375$$DView record in HAL
BookMark eNqNksFu1DAQhi1URLeFN0DIRzhksZ04XveAVFbQIq3EBc6W40wSrxK72E6lfYi-M45SeugB8MXS6PvHv2f-C3TmvAOE3lKypYTWH4_bptE9uC0jLJeYrEX1Am3oTrBiR0h9hjakJFVR0Zqfo4sYjyQfLvkrdF4yLiWh1QY9fLZ-gqTHiLVrcT-ejI-nUSfrHbYOD_OkXbzCe-_yWzaDuLXRhxZCxL57JogDtHi0_ZBiFieP0wDYhNnYrAt-hEVy48fe4ty21w4i4CEb8DHpaONr9LLLVuDN432Jfn798mN_Wxy-33zbXx8KUwmeirIBDZSypmEAnSBlp03JRV3LekcYzb8mjahayVu2Y3WTB2O4KRvNCNcCWlNeog9r30GP6i7YSYeT8tqq2-uDWmqESSlKwe9pZt-v7F3wv2aISU02GhjH7N7PUbFKiJpVhIj_QKkkssyGM_ruEZ2bCdonE382k4FqBUzwMQbonhBK1BIAdVRrANQSALUGIMuunslMXtqynBS0Hf8l_rSKIc_-3kJQ0VhwBlobwCTVevv3Br8BDejOtQ
CitedBy_id crossref_primary_10_1093_jxb_erad004
crossref_primary_10_1016_j_cca_2021_05_016
crossref_primary_10_3389_fpls_2021_697848
crossref_primary_10_1111_jcmm_70431
crossref_primary_10_1007_s10571_025_01541_5
crossref_primary_10_1016_j_bbagen_2023_130412
crossref_primary_10_34133_bmr_0158
crossref_primary_10_1093_plphys_kiac387
crossref_primary_10_1021_acschembio_1c00601
crossref_primary_10_1002_jimd_70004
crossref_primary_10_1016_j_jbc_2024_107567
crossref_primary_10_1016_j_csbj_2023_06_015
crossref_primary_10_1186_s12014_024_09507_3
crossref_primary_10_1016_j_jbc_2024_107378
crossref_primary_10_3390_molecules27061911
crossref_primary_10_3390_ijms232415883
crossref_primary_10_1016_j_isci_2021_103323
crossref_primary_10_3389_fcell_2022_903953
crossref_primary_10_1007_s00018_024_05551_2
crossref_primary_10_3390_nu15122799
crossref_primary_10_1016_j_bbadis_2023_166717
crossref_primary_10_1051_medsci_2021082
crossref_primary_10_1093_clinchem_hvac160
crossref_primary_10_1093_plphys_kiab122
crossref_primary_10_1007_s00439_021_02420_x
crossref_primary_10_30910_turkjans_1101428
crossref_primary_10_1371_journal_pone_0271062
crossref_primary_10_1038_s41467_023_41896_1
Cites_doi 10.1007/s00018-005-5410-y
10.1016/S0003-9861(03)00170-X
10.1091/mbc.9.5.1149
10.1371/journal.pone.0193228
10.1016/j.ajhg.2015.12.011
10.1016/j.bbadis.2008.10.020
10.1016/j.ajhg.2008.03.018
10.1007/978-94-007-5561-1_6
10.1073/pnas.1013642108
10.1111/nph.14526
10.1016/j.cub.2018.11.003
10.1093/hmg/ddw026
10.1016/j.ajhg.2012.05.002
10.1016/S1474-4422(14)70117-6
10.1074/jbc.M114.597831
10.3390/ijerph16193546
10.1093/toxsci/kfn231
10.1074/jbc.272.38.23503
10.1111/nph.14783
10.1016/j.neuro.2008.04.022
10.1186/s40360-016-0099-0
10.1093/glycob/cwv009
10.1111/jnc.13170
10.1093/ajcn/54.6.1065
10.1039/C9DT00508K
10.1104/pp.16.01895
10.3389/fnagi.2013.00033
10.1074/jbc.M707057200
10.7554/eLife.03941
10.1182/blood-2013-11-538686
10.1074/jbc.M303657200
10.1016/j.bbamcr.2006.05.007
10.1021/acs.analchem.9b04709
10.1016/j.neuro.2012.10.018
10.1016/S0005-2736(00)00138-3
10.1038/6784
10.1038/s41467-018-05191-8
10.1016/j.mib.2008.02.013
10.1016/j.bbagen.2017.01.011
10.1182/blood-2003-02-0425
10.1096/fj.201800387R
10.1074/jbc.M006902200
10.1016/0304-4165(76)90218-X
10.1016/j.yexcr.2014.07.007
10.1016/S0014-5793(99)01780-9
10.1016/j.bbagen.2017.11.006
10.33549/physiolres.931989
10.1016/S0304-3940(01)02144-9
10.1101/cshperspect.a004184
10.1074/jbc.RA119.012249
10.1074/jbc.M113.509984
10.1093/ajcn/60.6.949
10.1074/jbc.M304421200
10.1007/978-3-030-12457-1_8
10.1016/0166-2236(92)90081-I
10.1038/nature08300
10.1016/bs.acc.2015.10.002
10.1101/cshperspect.a016774
10.1016/j.ab.2013.07.037
10.1074/jbc.RA119.008762
10.1039/c0mt00074d
10.1111/j.1528-1157.1993.tb02584.x
10.1146/annurev-nutr-071714-034419
10.1038/s41598-018-21464-0
10.1111/j.0906-6705.2004.00197.x
10.1007/s00018-014-1617-0
10.1038/ncomms11601
10.1111/j.1471-4159.2010.06626.x
10.1016/j.bbrc.2014.02.020
10.21037/atm.2018.10.45
10.1016/j.ajhg.2016.12.010
10.1002/pro.235
10.1074/jbc.M116.728014
10.1371/journal.pone.0042988
10.1016/j.beem.2003.08.001
10.1289/ehp.877559
10.1083/jcb.200702081
10.1074/jbc.RA118.006270
10.1016/j.neuro.2008.02.012
10.1039/C8SC04386H
10.1002/iub.341
10.1093/oxfordjournals.jbchem.a121898
10.1007/s10534-010-9384-3
10.1042/BJ20060945
10.1016/j.molp.2018.04.008
10.1021/bi015538b
10.1021/bi9916473
10.1074/jbc.M117.790717
10.1007/s12035-007-0007-0
10.1111/j.1471-4159.1992.tb09778.x
10.1007/s11910-019-0942-y
10.1111/j.1600-0854.2010.01096.x
10.1002/1873-3468.12244
10.1111/cmi.12729
10.1079/BJN/2002534
10.1007/BF00965619
10.1079/BJN19810014
10.1007/8904_2015_455
10.1007/s00467-003-1293-z
10.1371/journal.pone.0085519
10.1091/mbc.e09-11-0985
10.1078/0171-9335-00224
10.2741/4665
10.1091/mbc.e03-03-0130
10.1073/pnas.1219871110
10.1038/celldisc.2017.25
10.1021/ja710162n
10.4067/S0716-97602006000100006
10.1074/jbc.R111.319343
10.1093/jn/119.10.1461
10.1007/8904_2012_172
10.1093/toxsci/kfq174
10.1074/jbc.M110.143248
10.1016/S1357-2725(99)00070-9
10.1038/srep24282
10.1523/JNEUROSCI.2329-14.2014
10.1016/j.neuroimage.2017.12.054
10.1016/j.bbrc.2004.07.128
10.1083/jcb.201311052
10.1007/s00018-008-7554-z
10.1039/C7MT00079K
10.1093/hmg/ddt146
10.1042/BCJ20160910
10.1042/BCJ20190488
10.1002/biof.5520100102
10.1023/A:1024485718843
10.1038/ng.2007.45
10.1038/s41586-020-1968-7
10.1111/j.1471-4159.2009.06534.x
10.1016/B978-0-12-394390-3.00010-0
10.1016/j.biochi.2019.07.016
10.1002/jbmr.326
10.1093/glycob/11.9.711
10.1016/j.tibs.2019.12.007
10.1016/S0021-9258(18)34061-4
10.1074/jbc.M610998200
10.1074/jbc.272.49.30873
10.1093/glycob/4.5.551
10.1073/pnas.1817815116
10.1107/S2059798319004169
10.2174/156652407780831548
10.1007/BF00446914
10.1016/B978-0-12-410502-7.00013-2
10.1021/cr900031u
10.1242/jcs.02856
10.1016/j.neulet.2017.08.006
10.1172/JCI90896
10.3390/biom4020435
10.1371/journal.pone.0100851
10.1016/j.ceb.2016.03.021
10.1146/annurev.biochem.76.061005.092322
10.1074/jbc.RA118.002324
10.1016/j.ceca.2011.01.006
10.1074/jbc.RA118.006250
10.1093/hmg/9.7.1131
10.1371/journal.pone.0007208
10.1016/S0021-9258(20)89624-0
10.1007/978-94-007-7500-8_4
10.1016/j.cell.2006.06.059
10.1016/j.ejmg.2017.10.012
10.1146/annurev.genom.8.080706.092327
10.1016/j.sbi.2004.09.006
10.1210/jc.2016-3443
10.1074/jbc.274.8.4481
10.1042/BJ20041206
10.1093/oxfordjournals.jbchem.a021492
10.3390/ijms18122708
10.1016/j.tice.2016.06.006
10.1091/mbc.e17-05-0326
10.1182/blood-2008-04-150953
10.1016/j.ajhg.2015.11.003
10.1016/j.bbamcr.2004.08.018
10.1155/2014/371256
10.1074/jbc.M413116200
10.1016/j.tox.2017.05.015
ContentType Journal Article
Copyright 2020 Elsevier B.V.
Copyright © 2020 Elsevier B.V. All rights reserved.
Distributed under a Creative Commons Attribution 4.0 International License
Copyright_xml – notice: 2020 Elsevier B.V.
– notice: Copyright © 2020 Elsevier B.V. All rights reserved.
– notice: Distributed under a Creative Commons Attribution 4.0 International License
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7S9
L.6
1XC
VOOES
DOI 10.1016/j.bbagen.2020.129674
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
Hyper Article en Ligne (HAL)
Hyper Article en Ligne (HAL) (Open Access)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
DatabaseTitleList
AGRICOLA
MEDLINE

MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Chemistry
Biology
EISSN 1872-8006
ExternalDocumentID oai_HAL_hal_02997375v1
32599014
10_1016_j_bbagen_2020_129674
S0304416520301860
Genre Research Support, Non-U.S. Gov't
Journal Article
Review
GroupedDBID ---
--K
--M
.~1
0R~
1B1
1RT
1~.
1~5
23N
3O-
4.4
457
4G.
53G
5GY
5RE
5VS
7-5
71M
8P~
9JM
AACTN
AAEDT
AAEDW
AAIAV
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAQXK
AAXUO
ABEFU
ABFNM
ABGSF
ABMAC
ABUDA
ABXDB
ABYKQ
ACDAQ
ACIUM
ACRLP
ADBBV
ADEZE
ADMUD
ADUVX
AEBSH
AEHWI
AEKER
AFKWA
AFTJW
AFXIZ
AGHFR
AGRDE
AGUBO
AGYEJ
AHHHB
AIEXJ
AIKHN
AITUG
AJBFU
AJOXV
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLXMC
CS3
DOVZS
EBS
EFJIC
EFLBG
EJD
EO8
EO9
EP2
EP3
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
GBLVA
HLW
HVGLF
HZ~
IHE
J1W
KOM
LX3
M41
MO0
N9A
O-L
O9-
OAUVE
OHT
OZT
P-8
P-9
PC.
Q38
R2-
ROL
RPZ
SBG
SCC
SDF
SDG
SDP
SES
SEW
SPCBC
SSU
SSZ
T5K
UQL
WH7
WUQ
XJT
XPP
~G-
AAHBH
AATTM
AAXKI
AAYWO
AAYXX
ABWVN
ACRPL
ACVFH
ADCNI
ADNMO
AEIPS
AEUPX
AFJKZ
AFPUW
AGCQF
AGQPQ
AGRNS
AIGII
AIIUN
AKBMS
AKRWK
AKYEP
ANKPU
APXCP
BNPGV
CITATION
SSH
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7S9
L.6
1XC
VOOES
ID FETCH-LOGICAL-c475t-3beae112bb2eef703fac357669680213040b74d95d2826b674c5c3ba205a7edc3
IEDL.DBID .~1
ISSN 0304-4165
1872-8006
IngestDate Fri May 09 12:22:35 EDT 2025
Fri Jul 11 01:53:10 EDT 2025
Fri Jul 11 08:49:10 EDT 2025
Wed Feb 19 02:29:26 EST 2025
Thu Apr 24 22:53:14 EDT 2025
Tue Jul 01 00:22:13 EDT 2025
Fri Feb 23 02:47:22 EST 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 10
Keywords Glycosylation
Congenital disorders of glycosylation
Biometal homeostasis
Manganese
TMEM165
Language English
License Copyright © 2020 Elsevier B.V. All rights reserved.
Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c475t-3beae112bb2eef703fac357669680213040b74d95d2826b674c5c3ba205a7edc3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ORCID 0000-0002-0814-221X
OpenAccessLink https://hal.science/hal-02997375
PMID 32599014
PQID 2419093703
PQPubID 23479
ParticipantIDs hal_primary_oai_HAL_hal_02997375v1
proquest_miscellaneous_2477624007
proquest_miscellaneous_2419093703
pubmed_primary_32599014
crossref_primary_10_1016_j_bbagen_2020_129674
crossref_citationtrail_10_1016_j_bbagen_2020_129674
elsevier_sciencedirect_doi_10_1016_j_bbagen_2020_129674
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate October 2020
2020-10-00
20201001
2020-10
PublicationDateYYYYMMDD 2020-10-01
PublicationDate_xml – month: 10
  year: 2020
  text: October 2020
PublicationDecade 2020
PublicationPlace Netherlands
PublicationPlace_xml – name: Netherlands
PublicationTitle Biochimica et biophysica acta. General subjects
PublicationTitleAlternate Biochim Biophys Acta Gen Subj
PublicationYear 2020
Publisher Elsevier B.V
Elsevier
Publisher_xml – name: Elsevier B.V
– name: Elsevier
References Foulquier, Amyere, Jaeken, Zeevaert, Schollen, Race, Bammens, Morelle, Rosnoblet, Legrand, Demaegd, Buist, Cheillan, Guffon, Morsomme, Annaert, Freeze, Van Schaftingen, Vikkula, Matthijs (bb0555) 2012; 91
Yonekura, Toyoshima (bb0725) 2016; 590
Sprong, Degroote, Nilsson, Kawakita, Ishida, van der Sluijs, van Meer (bb0185) 2003; 14
Lebredonchel, Houdou, Hoffmann, Kondratska, Krzewinski, Vicogne, Rice, Klein, Foulquier (bb0925) 2019; 476
Bonda, Lee, Blair, Zhu, Perry, Smith (bb0395) 2011; 3
Scheiber, Wu, Morgan, Zhao (bb0685) 2019; 294
Sakuntabhai, Ruiz-Perez, Carter, Jacobsen, Burge, Monk, Smith, Munro, O’Donovan, Craddock, Kucherlapati, Rees, Owen, Lathrop, Monaco, Strachan, Hovnanian (bb0485) 1999; 21
Chang, He, Lam (bb0520) 2018; 6
Foot, Dalton, Shearwin-Whyatt, Dorstyn, Tan, Yang, Kumar (bb0945) 2008; 112
Willer, Inamori, Venzke, Harvey, Morgensen, Hara, de Bernabé, Yu, Wright, Campbell (bb0125) 2014; 3
Blommaert, Péanne, Cherepanova, Rymen, Staels, Jaeken, Race, Keldermans, Souche, Corveleyn, Sparkes, Bhattacharya, Devalck, Schrijvers, Foulquier, Gilmore, Matthijs (bb0565) 2019; 116
Williams, Kwakye, Wegrzynowicz, Li, Aschner, Erikson, Bowman (bb0390) 2010; 117
Barnese, Gralla, Cabelli, Valentine (bb0065) 2008; 130
Ramakrishnan, Boeggeman, Ramasamy, Qasba (bb0115) 2004; 14
Dowling, Di Costanzo, Gennadios, Christianson (bb0225) 2008; 65
Tu, Nelson, Bezprozvanny, Wang, Lee, Hao, Serneels, De Strooper, Yu, Bezprozvanny (bb0470) 2006; 126
Garshasbi, Hadavi, Habibi, Kahrizi, Kariminejad, Behjati, Tzschach, Najmabadi, Ropers, Kuss (bb0570) 2008; 82
Purich, Fromm, Rudolph (bb0215) 1973; 39
Xia, Zhang, Li, Jiang, Harper, Liu, Cummings, He (bb0845) 2013; 442
Peanne, de Lonlay, Foulquier, Kornak, Lefeber, Morava, Perez, Seta, Thiel, Van Schaftingen, Matthijs, Jaeken (bb0525) 2018; 61
Nishito, Tsuji, Fujishiro, Takeda, Yamazaki, Teranishi, Okazaki, Matsunaga, Tuschl, Rao, Kono, Miyajima, Narita, Himeno, Kambe (bb0430) 2016; 291
Minamida, Aoki, Natsuka, Omichi, Fukase, Kusumoto, Hase (bb0135) 1996; 120
Ponka, Lok (bb0645) 1999; 31
Müller, Schöttler, Schön, Prante, Brinkmann, Kuhn, Götting, Kleesiek (bb0155) 2005; 386
Yin, Jiang, Lee, Ni, Erikson, Milatovic, Bowman, Aschner (bb0705) 2010; 112
Cellier (bb0610) 2012; 69
Gomez-Villafuertes, Mellström, Naranjo (bb0465) 2007; 35
Xiang, Mohamalawari, Rao (bb0750) 2005; 280
Daniel, Winchester, Warren (bb0245) 1994; 4
Foulquier (bb0825) 2009; 1792
Hirayama, Inden, Tsuboi, Niwa, Uchida, Naka, Hozumi, Nagasawa (bb0960) 2019; 10
Ye, Park, Gugnani, Betharia, Pino-Figueroa, Kim (bb0630) 2017; 9
Bedenk, Almeida-Corrêa, Jurik, Dedic, Grünecker, Genewsky, Kaltwasser, Riebe, Deussing, Czisch, Wotjak (bb0590) 2018; 169
Reddi, Jensen, Culotta (bb0740) 2009; 109
Schmitt-Ulms, Ehsani, Watts, Westaway, Wille (bb0515) 2009; 4
Wang, Yang, Huang, He, Li, Zhang, Zhang, Tang (bb0865) 2020; 92
Peres, Schettinger, Chen, Carvalho, Avila, Bowman, Aschner (bb0410) 2016; 17
Nikoletopoulou, Tavernarakis (bb0455) 2018; 663
Xin, Gao, Wang, Qiang, Imam, Li, Wang, Zhang, Zhang, Yu, Wang, Luo, Shi, Xu, Hojyo, Fukada, Min, Wang (bb0600) 2017; 3
Nevo, Nelson (bb0540) 2006; 1763
Leyssens, Vinck, Van Der Straeten, Wuyts, Maes (bb0240) 2017; 387
Roth, Ponzoni, Aschner (bb0275) 2013; 12
Zhao, Gao, Enns, Knutson (bb0690) 2010; 285
Gandini, Schmidt, Husted, Schneider, Leister (bb0790) 2017; 215
de Vries, Storm, Rotteveel, Verdonk, van Duin, van den Eijnden, Joziasse, Bunschoten (bb0180) 2001; 11
Snyder, Palmer, Reinhardt, Cunningham (bb0890) 2019; 294
Jaeken, Matthijs (bb0530) 2007; 8
Freeze (bb0535) 2007; 7
Demaegd, Colinet, Deschamps, Morsomme (bb0770) 2014; 9
Carmeliet, Van Cromphaut, Daci, Maes, Bouillon (bb0475) 2003; 17
Kienzle, Basnet, Crevenna, Beck, Habermann, Mizuno, von Blume (bb0755) 2014; 206
Morelle, Potelle, Witters, Wong, Climer, Lupashin, Matthijs, Gadomski, Jaeken, Cassiman, Morava, Foulquier (bb0855) 2017; 102
Sørensen, Holemans, van Veen, Martin, Arslan, Haagendahl, Holen, Hamouda, Eggermont, Palmgren, Vangheluwe (bb0730) 2018; 13
Carmona, Devès, Roudeau, Cloetens, Bohic, Ortega (bb0355) 2010; 1
Colinet, Thines, Deschamps, Flémal, Demaegd, Morsomme (bb0900) 2017; 19
Gibbons, Dixon, Hallis, Russell, Sansom, Symonds (bb0280) 1976; 444
Milner, Baksh, Shemanko, Carpenter, Smillie, Vance, Opas, Michalak (bb0315) 1991; 266
Schneider, Steinberger, Herdean, Gandini, Eisenhut, Kurz, Morper, Hoecker, Rühle, Labs, Flügge, Geimer, Schmidt, Husted, Weber, Spetea, Leister (bb0800) 2016; 28
Yang, Xu (bb0445) 2014; 2014
Horning, Caito, Tipps, Bowman, Aschner (bb0070) 2015; 35
Eisenhut, Hoecker, Schmidt, Basgaran, Flachbart, Jahns, Eser, Geimer, Husted, Weber, Leister, Schneider (bb0775) 2018; 11
Lin, Vann, Doulias, Wang, Landesberg, Li, Ricciotti, Scalia, He, Hand, Rader (bb0695) 2017; 127
Venkat, Linstedt (bb0875) 2017; 28
Sudbrak, Brown, Dobson-Stone, Carter, Ramser, White, Healy, Dissanayake, Larrègue, Perrussel, Lehrach, Munro, Strachan, Burge, Hovnanian, Monaco (bb0490) 2000; 9
Novák, Soukup (bb0300) 2011; 60
Aradhyam, Balivada, Kanuru, Vadivel, Vidhya (bb0325) 2010; 62
Szewczyk (bb0460) 2013; 5
Roth (bb0285) 2006; 39
Colinet, Sengottaiyan, Deschamps, Colsoul, Thines, Demaegd, Duchene, Foulquier, Hols, Morsomme (bb0850) 2016; 6
Krzewinski-Recchi, Potelle, Mir, Vicogne, Dulary, Duvet, Morelle, de Bettignies, Foulquier (bb0810) 2017; 1861
Argüello, Raimunda, González-Guerrero (bb0370) 2012; 287
Finley, Johnson, Johnson (bb0625) 1994; 60
Bond, Clements, Ashby, Collyer, Harrop, Hopwood, Guss (bb0035) 1997; 1993
Techau, Valdez-Taubas, Popoff, Francis, Seaman, Blackwell (bb0605) 2007; 282
Leyva-Illades, Chen, Zogzas, Hutchens, Mercado, Swaim, Morrisett, Bowman, Aschner, Mukhopadhyay (bb0435) 2014; 34
Yada, Sato, Kaseyama, Gotoh, Iwasaki, Kikuchi, Kwon, Togayachi, Kudo, Watanabe, Narimatsu, Kimata (bb0165) 2003; 278
Williams (bb0305) 2006; 119
Chebassier, El Houssein, Viegas, Dréno (bb0090) 2004; 13
Dubail, Huber, Chantepie, Sonntag, Tüysüz, Mihci, Gordon, Steichen-Gersdorf, Amiel, Nur, Stolte-Dijkstra, van Eerde, van Gassen, Breugem, Stegmann, Lekszas, Maroofian, Karimiani, Bruneel, Seta (bb0965) 2018; 9
Ash, Schramm (bb0365) 1982; 257
Tsutsui, Ramakrishnan, Qasba (bb0170) 2013; 288
Davidsson, Lönnerdal, Sandström, Kunz, Keen (bb0655) 1989; 119
Anagianni, Tuschl (bb0425) 2019; 19
Potelle, Morelle, Dulary, Duvet, Vicogne, Spriet, Krzewinski-Recchi, Morsomme, Jaeken, Matthijs, De Bettignies, Foulquier (bb0760) 2016; 25
Takeya, Hosomi, Kogure (bb0145) 1987; 101
Gunter, Gerstner, Gunter, Malecki, Gelein, Valentine, Aschner, Yule (bb0650) 2013; 34
Davidsson, Cederblad, Lönnerdal, Sandström (bb0635) 1991; 54
Van Baelen, Dode, Vanoevelen, Callewaert, De Smedt, Missiaen, Parys, Raeymaekers, Wuytack (bb0025) 2004; 1742
Bangera, Gowda, Sagurthi, Murthy (bb0250) 2019; 75
Micaroni, Perinetti, Berrie, Mironov (bb0735) 2010; 11
Wedler, Ley, Grippo (bb0345) 1989; 14
Venkatesan, Kuntz, Rose (bb0260) 2009; 18
Tuschl, Meyer, Valdivia, Zhao, Dadswell, Abdul-Sada, Hung, Simpson, Chong, Jacques, Woltjer, Eaton, Gregory, Sanford, Kara, Houlden, Cuno, Prokisch, Valletta, Tiranti (bb0680) 2016; 7
Thompson, Wessling-Resnick (bb0920) 2019
Chesters, Will (bb0270) 1981; 46
van Veen, Martin, Van den Haute, Benoy, Lyons, Vanhoutte, Kahler, Decuypere, Gelders, Lambie, Zielich, Swinnen, Annaert, Agostinis, Ghesquière, Verhelst, Baekelandt, Eggermont, Vangheluwe (bb0450) 2020; 578
Inamori, Willer, Hara, Venzke, Anderson, Clarke, Guicheney, Bönnemann, Moore, Campbell (bb0130) 2014; 289
Cherepanova, Shrimal, Gilmore (bb0580) 2016; 41
Burd, Cullen (bb0950) 2014; 6
Ishikawa, Xu, Ogura, Manning, Irvine (bb0100) 2012; 7
Zeevaert, de Zegher, Sturiale, Garozzo, Smet, Moens, Matthijs, Jaeken (bb0840) 2013; 8
Missiaen, Raeymaekers, Dode, Vanoevelen, Van Baelen, Parys, Callewaert, De Smedt, Segaert, Wuytack (bb0495) 2004; 322
Whittaker (bb0060) 2000; 37
Chen, Smaardijk, Mattelaer, Pamula, Vandecaetsbeek, Vanoevelen, Wuytack, Lescrinier, Eggermont, Vangheluwe (bb0910) 2019; 294
Lebredonchel, Houdou, Potelle, de Bettignies, Schulz, Krzewinski Recchi, Lupashin, Legrand, Klein, Foulquier (bb0905) 2019; 165
Leitch, Feng, Muend, Braiterman, Hubbard, Rao (bb0500) 2011; 24
Radisky, Kaplan (bb0915) 1999; 274
Stribny, Thines, Deschamps, Goffin, Morsomme (bb0885) 2020; 295
Isani, Carpenè (bb0290) 2014; 4
Honoré, Vorum (bb0320) 2000; 466
Gao, Xie, Yang, Xu, Li, Wang, Chen, Huang (bb0955) 2018; 217
Mukhopadhyay, Linstedt (bb0505) 2011; 108
Li, Kondo, Numaguchi, Kobayashi, Aoki, Inoue, Okumura, Murohara (bb0085) 2008; 1979
Reinhardt, Lippolis, Sacco (bb0895) 2014; 445
Dulary, Yu, Houdou, de Bettignies, Decool, Potelle, Duvet, Krzewinski-Recchi, Garat, Matthijs, Guerardel, Foulquier (bb0930) 2018; 1862
Brini, Ottolini, Calì, Carafoli (bb0265) 2013; 13
Elíes, Yáñez, Pereira, Gil-Longo, MacDougall, Campos-Toimil (bb0020) 2020; 1131
Mukhopadhyay, Bachert, Smith, Linstedt (bb0440) 2010; 21
Roohani, Hurrell, Kelishadi, Schulin (bb0235) 2013; 18
Glasdam, Glasdam, Peters (bb0040) 2016; 73
Brandenburg, Schoffman, Kurz, Krämer, Keren, Weber, Eisenhut (bb0795) 2017; 173
Baimbridge, Celio, Rogers (bb0335) 1992; 15
Kalia, Jiang, Zheng (bb0340) 2008; 29
Okajima, Nakamura, Uchikawa, Haslam, Numata, Furukawa, Urano, Furukawa (bb0175) 2000; 275
Finley, Davis (bb0615) 1999; 10
Palma, Morais, Coelho, Costa (bb0140) 2004; 17
Wandall, Hassan, Mirgorodskaya, Kristensen, Roepstorff, Bennett, Nielsen, Hollingsworth, Burchell, Taylor-Papadimitriou, Clausen (bb0120) 1997; 272
Inamori, Willer, Hara, Venzke, Anderson, Clarke, Guicheney, Bönnemann, Moore, Campbell (bb0200) 2014; 289
Vandecaetsbeek, Vangheluwe, Raeymaekers, Wuytack, Vanoevelen (bb0745) 2011; 3
Jansen, Timal, van Scherpenzeel, Michelakakis, Vicogne, Ashikov, Moraitou, Hoischen, Huijben, Steenbergen, van den Boogert, Porta, Calvo, Mavrikou, Cenacchi, van den Bogaart, Salomon, Holleboom, Rodenburg, Drenth (bb0835) 2016; 98
Jitrapakdee, Vidal-Puig, Wallace (bb0205) 2006; 63
Takagishi, Hara, Fukada (bb0675) 2017; 18
Rohde, Bastidas, Puria, Cardenas (bb0075) 2008; 11
Martins, Morcillo, Ijomone, Venkataramani, Harrison, Lee, Bowman, Aschner (bb0405) 2019; 16
Gavin, Gunt
Palma (10.1016/j.bbagen.2020.129674_bb0140) 2004; 17
Bonda (10.1016/j.bbagen.2020.129674_bb0395) 2011; 3
Pizzo (10.1016/j.bbagen.2020.129674_bb0295) 2011; 50
Bond (10.1016/j.bbagen.2020.129674_bb0035) 1997; 1993
Carmona (10.1016/j.bbagen.2020.129674_bb0355) 2010; 1
Sprong (10.1016/j.bbagen.2020.129674_bb0185) 2003; 14
Takeya (10.1016/j.bbagen.2020.129674_bb0145) 1987; 101
Brini (10.1016/j.bbagen.2020.129674_bb0265) 2013; 13
Yin (10.1016/j.bbagen.2020.129674_bb0705) 2010; 112
Whittaker (10.1016/j.bbagen.2020.129674_bb0060) 2000; 37
Ye (10.1016/j.bbagen.2020.129674_bb0630) 2017; 9
Okajima (10.1016/j.bbagen.2020.129674_bb0175) 2000; 275
Xin (10.1016/j.bbagen.2020.129674_bb0600) 2017; 3
Lièvremont (10.1016/j.bbagen.2020.129674_bb0310) 1997; 272
Ponka (10.1016/j.bbagen.2020.129674_bb0645) 1999; 31
Novák (10.1016/j.bbagen.2020.129674_bb0300) 2011; 60
Bammens (10.1016/j.bbagen.2020.129674_bb0820) 2015; 25
Finley (10.1016/j.bbagen.2020.129674_bb0625) 1994; 60
Colinet (10.1016/j.bbagen.2020.129674_bb0850) 2016; 6
Krzewinski-Recchi (10.1016/j.bbagen.2020.129674_bb0810) 2017; 1861
Nyman (10.1016/j.bbagen.2020.129674_bb0095) 2011; 26
10.1016/j.bbagen.2020.129674_bb0380
Carl (10.1016/j.bbagen.2020.129674_bb0080) 1993; 34
Schmitt-Ulms (10.1016/j.bbagen.2020.129674_bb0515) 2009; 4
Gavin (10.1016/j.bbagen.2020.129674_bb0710) 1999; 20
Xiang (10.1016/j.bbagen.2020.129674_bb0750) 2005; 280
Li (10.1016/j.bbagen.2020.129674_bb0575) 2014; 123
Daniel (10.1016/j.bbagen.2020.129674_bb0245) 1994; 4
Chebassier (10.1016/j.bbagen.2020.129674_bb0090) 2004; 13
Hirayama (10.1016/j.bbagen.2020.129674_bb0960) 2019; 10
Burd (10.1016/j.bbagen.2020.129674_bb0950) 2014; 6
Dürr (10.1016/j.bbagen.2020.129674_bb0940) 1998; 9
Rohde (10.1016/j.bbagen.2020.129674_bb0075) 2008; 11
Nikoletopoulou (10.1016/j.bbagen.2020.129674_bb0455) 2018; 663
Davies (10.1016/j.bbagen.2020.129674_bb0030) 1995; 1993
Yada (10.1016/j.bbagen.2020.129674_bb0160) 2003; 278
Freeze (10.1016/j.bbagen.2020.129674_bb0535) 2007; 7
Ward (10.1016/j.bbagen.2020.129674_bb0400) 2014; 13
Xia (10.1016/j.bbagen.2020.129674_bb0845) 2013; 442
Dubail (10.1016/j.bbagen.2020.129674_bb0965) 2018; 9
Stangherlin (10.1016/j.bbagen.2020.129674_bb0050) 2018; 28
Dowling (10.1016/j.bbagen.2020.129674_bb0225) 2008; 65
Peres (10.1016/j.bbagen.2020.129674_bb0410) 2016; 17
Davidsson (10.1016/j.bbagen.2020.129674_bb0655) 1989; 119
Schlingmann (10.1016/j.bbagen.2020.129674_bb0480) 2004; 19
Hoecker (10.1016/j.bbagen.2020.129674_bb0780) 2020; 9
Schulte Althoff (10.1016/j.bbagen.2020.129674_bb0815) 2016; 26
Lyons (10.1016/j.bbagen.2020.129674_bb0010) 2007
Nishito (10.1016/j.bbagen.2020.129674_bb0430) 2016; 291
Baimbridge (10.1016/j.bbagen.2020.129674_bb0335) 1992; 15
Roohani (10.1016/j.bbagen.2020.129674_bb0235) 2013; 18
Jitrapakdee (10.1016/j.bbagen.2020.129674_bb0205) 2006; 63
Williams (10.1016/j.bbagen.2020.129674_bb0305) 2006; 119
Davidsson (10.1016/j.bbagen.2020.129674_bb0635) 1991; 54
Chen (10.1016/j.bbagen.2020.129674_bb0190) 2001; 40
Venkat (10.1016/j.bbagen.2020.129674_bb0875) 2017; 28
Elíes (10.1016/j.bbagen.2020.129674_bb0020) 2020; 1131
Eisenhut (10.1016/j.bbagen.2020.129674_bb0775) 2018; 11
Takagishi (10.1016/j.bbagen.2020.129674_bb0675) 2017; 18
Chesters (10.1016/j.bbagen.2020.129674_bb0270) 1981; 46
Kai (10.1016/j.bbagen.2020.129674_bb0210) 2003; 414
Sudbrak (10.1016/j.bbagen.2020.129674_bb0490) 2000; 9
Szewczyk (10.1016/j.bbagen.2020.129674_bb0460) 2013; 5
Kalia (10.1016/j.bbagen.2020.129674_bb0340) 2008; 29
Techau (10.1016/j.bbagen.2020.129674_bb0605) 2007; 282
Mukhopadhyay (10.1016/j.bbagen.2020.129674_bb0505) 2011; 108
Ishikawa (10.1016/j.bbagen.2020.129674_bb0100) 2012; 7
Müller (10.1016/j.bbagen.2020.129674_bb0155) 2005; 386
Potelle (10.1016/j.bbagen.2020.129674_bb0760) 2016; 25
Choi (10.1016/j.bbagen.2020.129674_bb0700) 2018; 8
Sørensen (10.1016/j.bbagen.2020.129674_bb0730) 2018; 13
Morelle (10.1016/j.bbagen.2020.129674_bb0855) 2017; 102
Das (10.1016/j.bbagen.2020.129674_bb0360) 2019; 2003
Chen (10.1016/j.bbagen.2020.129674_bb0620) 2018; 23
Barnese (10.1016/j.bbagen.2020.129674_bb0065) 2008; 130
10.1016/j.bbagen.2020.129674_bb0375
Dong (10.1016/j.bbagen.2020.129674_bb0585) 2010; 113
Ramakrishnan (10.1016/j.bbagen.2020.129674_bb0115) 2004; 14
Jaeken (10.1016/j.bbagen.2020.129674_bb0530) 2007; 8
Forbes (10.1016/j.bbagen.2020.129674_bb0595) 2003; 102
Dulary (10.1016/j.bbagen.2020.129674_bb0930) 2018; 1862
Kornak (10.1016/j.bbagen.2020.129674_bb0550) 2008; 40
Vasanthakumar (10.1016/j.bbagen.2020.129674_bb0545) 2020; 45
Willer (10.1016/j.bbagen.2020.129674_bb0125) 2014; 3
Purich (10.1016/j.bbagen.2020.129674_bb0215) 1973; 39
van Veen (10.1016/j.bbagen.2020.129674_bb0450) 2020; 578
Argüello (10.1016/j.bbagen.2020.129674_bb0370) 2012; 287
Gandini (10.1016/j.bbagen.2020.129674_bb0790) 2017; 215
Scheiber (10.1016/j.bbagen.2020.129674_bb0685) 2019; 294
Honoré (10.1016/j.bbagen.2020.129674_bb0320) 2000; 466
Isani (10.1016/j.bbagen.2020.129674_bb0290) 2014; 4
Jansen (10.1016/j.bbagen.2020.129674_bb0835) 2016; 98
Rosnoblet (10.1016/j.bbagen.2020.129674_bb0805) 2013; 22
Gao (10.1016/j.bbagen.2020.129674_bb0955) 2018; 217
Cashman (10.1016/j.bbagen.2020.129674_bb0015) 2002; 87
Paull (10.1016/j.bbagen.2020.129674_bb0105) 2014; 329
Venkatesan (10.1016/j.bbagen.2020.129674_bb0260) 2009; 18
Micaroni (10.1016/j.bbagen.2020.129674_bb0735) 2010; 11
Hirata (10.1016/j.bbagen.2020.129674_bb0415) 2001; 311
Kienzle (10.1016/j.bbagen.2020.129674_bb0755) 2014; 206
Yonekura (10.1016/j.bbagen.2020.129674_bb0725) 2016; 590
Chen (10.1016/j.bbagen.2020.129674_bb0660) 2015; 134
Zeinert (10.1016/j.bbagen.2020.129674_bb0785) 2018; 293
Cherepanova (10.1016/j.bbagen.2020.129674_bb0580) 2016; 41
Thines (10.1016/j.bbagen.2020.129674_bb0860) 2018; 293
Houdou (10.1016/j.bbagen.2020.129674_bb0935) 2019; 33
Williams (10.1016/j.bbagen.2020.129674_bb0390) 2010; 117
Wandall (10.1016/j.bbagen.2020.129674_bb0120) 1997; 272
Lairson (10.1016/j.bbagen.2020.129674_bb0110) 2008; 77
Lebredonchel (10.1016/j.bbagen.2020.129674_bb0905) 2019; 165
Guerinot (10.1016/j.bbagen.2020.129674_bb0670) 2000; 1465
Reinhardt (10.1016/j.bbagen.2020.129674_bb0895) 2014; 445
Radisky (10.1016/j.bbagen.2020.129674_bb0915) 1999; 274
Chang (10.1016/j.bbagen.2020.129674_bb0520) 2018; 6
Snyder (10.1016/j.bbagen.2020.129674_bb0890) 2019; 294
Wedler (10.1016/j.bbagen.2020.129674_bb0345) 1989; 14
Snyder (10.1016/j.bbagen.2020.129674_bb0870) 2017; 7
Cellier (10.1016/j.bbagen.2020.129674_bb0610) 2012; 69
Au (10.1016/j.bbagen.2020.129674_bb0640) 2008; 29
Clarkson (10.1016/j.bbagen.2020.129674_bb0385) 1987; 75
Waldron (10.1016/j.bbagen.2020.129674_bb0005) 2009; 460
Horning (10.1016/j.bbagen.2020.129674_bb0070) 2015; 35
Aradhyam (10.1016/j.bbagen.2020.129674_bb0325) 2010; 62
Foulquier (10.1016/j.bbagen.2020.129674_bb0825) 2009; 1792
Demaegd (10.1016/j.bbagen.2020.129674_bb0770) 2014; 9
Tuschl (10.1016/j.bbagen.2020.129674_bb0055) 2013; 110
Anagianni (10.1016/j.bbagen.2020.129674_bb0425) 2019; 19
Bangera (10.1016/j.bbagen.2020.129674_bb0250) 2019; 75
Putrament (10.1016/j.bbagen.2020.129674_bb0420) 1977; 151
Finley (10.1016/j.bbagen.2020.129674_bb0615) 1999; 10
Vandecaetsbeek (10.1016/j.bbagen.2020.129674_bb0745) 2011; 3
Demaegd (10.1016/j.bbagen.2020.129674_bb0765) 2013; 110
Bedenk (10.1016/j.bbagen.2020.129674_bb0590) 2018; 169
Yamasaki (10.1016/j.bbagen.2020.129674_bb0230) 2007; 177
Roth (10.1016/j.bbagen.2020.129674_bb0285) 2006; 39
Leitch (10.1016/j.bbagen.2020.129674_bb0500) 2011; 24
Persson (10.1016/j.bbagen.2020.129674_bb0150) 2007; 282
Li (10.1016/j.bbagen.2020.129674_bb0085) 2008; 1979
Carmeliet (10.1016/j.bbagen.2020.129674_bb0475) 2003; 17
Leyssens (10.1016/j.bbagen.2020.129674_bb0240) 2017; 387
Zeevaert (10.1016/j.bbagen.2020.129674_bb0840) 2013; 8
de Vries (10.1016/j.bbagen.2020.129674_bb0180) 2001; 11
Inamori (10.1016/j.bbagen.2020.129674_bb0130) 2014; 289
Reddi (10.1016/j.bbagen.2020.129674_bb0740) 2009; 109
Colinet (10.1016/j.bbagen.2020.129674_bb0900) 2017; 19
Yang (10.1016/j.bbagen.2020.129674_bb0445) 2014; 2014
Garshasbi (10.1016/j.bbagen.2020.129674_bb0570) 2008; 82
Fothergill-Gilmore (10.1016/j.bbagen.2020.129674_bb0220) 1989; 62
Brandenburg (10.1016/j.bbagen.2020.129674_bb0795) 2017; 173
Dulary (10.1016/j.bbagen.2020.129674_bb0715) 2017; 49
Mukhopadhyay (10.1016/j.bbagen.2020.129674_bb0440) 2010; 21
Sakuntabhai (10.1016/j.bbagen.2020.129674_bb0485) 1999; 21
Zhao (10.1016/j.bbagen.2020.129674_bb0690) 2010; 285
Chen (10.1016/j.bbagen.2020.129674_bb0910) 2019; 294
Suzuki (10.1016/j.bbagen.2020.129674_bb0255) 2006; 400
Aschner (10.1016/j.bbagen.2020.129674_bb0350) 1992; 58
Potelle (10.1016/j.bbagen.2020.129674_bb0880) 2017; 474
Nevo (10.1016/j.bbagen.2020.129674_bb0540) 2006; 1763
Tu (10.1016/j.bbagen.2020.129674_bb0470) 2006; 126
Jursa (10.1016/j.bbagen.2020.129674_bb0665) 2009; 107
Schneider (10.1016/j.bbagen.2020.129674_bb0800) 2016; 28
Tsutsui (10.1016/j.bbagen.2020.129674_bb0170) 2013; 288
Lebredonchel (10.1016/j.bbagen.2020.129674_bb0925) 2019; 476
Romani (10.1016/j.bbagen.2020.129674_bb0045) 2011
Ash (10.1016/j.bbagen.2020.129674_bb0365) 1982; 257
Inamori (10.1016/j.bbagen.2020.129674_bb0200) 2014; 289
Leyva-Illades (10.1016/j.bbagen.2020.129674_bb0435) 2014; 34
Gibbons (10.1016/j.bbagen.2020.129674_bb0280) 1976; 444
Van Damme (10.1016/j.bbagen.2020.129674_bb0830) 2017; 100
Martins (10.1016/j.bbagen.2020.129674_bb0405) 2019; 16
Van Baelen (10.1016/j.bbagen.2020.129674_bb0025) 2004; 1742
Yada (10.1016/j.bbagen.2020.129674_bb0165) 2003; 278
Gunter (10.1016/j.bbagen.2020.129674_bb0650) 2013; 34
Blommaert (10.1016/j.bbagen.2020.129674_bb0565) 2019; 116
Foot (10.1016/j.bbagen.2020.129674_bb0945) 2008; 112
Milner (10.1016/j.bbagen.2020.129674_bb0315) 1991; 266
Thompson (10.1016/j.bbagen.2020.129674_bb0920) 2019
Morel-Huaux (10.1016/j.bbagen.2020.129674_bb0330) 2002; 81
Gomez-Villafuertes (10.1016/j.bbagen.2020.129674_bb0465) 2007; 35
Roth (10.1016/j.bbagen.2020.129674_bb0275) 2013; 12
Lin (10.1016/j.bbagen.2020.129674_bb0695) 2017; 127
Wang (10.1016/j.bbagen.2020.129674_bb0865) 2020; 92
Cohen (10.1016/j.bbagen.2020.129674_bb0720) 2013; 8
Peanne (10.1016/j.bbagen.2020.129674_bb0525) 2018; 61
Missiaen (10.1016/j.bbagen.2020.129674_bb0495) 2004
References_xml – volume: 6
  start-page: 477
  year: 2018
  ident: bb0520
  article-title: Congenital disorders of glycosylation
  publication-title: Ann. Transl. Med.
– year: 2019
  ident: bb0920
  article-title: ZIP14 Is Degraded in Response to Manganese Exposure
– year: 2011
  ident: bb0045
  article-title: Intracellular magnesium homeostasis
  publication-title: Magnes. Cent. Nerv. Syst
– volume: 289
  start-page: 28138
  year: 2014
  end-page: 28148
  ident: bb0130
  article-title: Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues
  publication-title: J. Biol. Chem.
– volume: 9
  start-page: 3087
  year: 2018
  ident: bb0965
  article-title: SLC10A7 mutations cause a skeletal dysplasia with amelogenesis imperfecta mediated by GAG biosynthesis defects
  publication-title: Nat. Commun.
– volume: 274
  start-page: 4481
  year: 1999
  end-page: 4484
  ident: bb0915
  article-title: Regulation of transition metal transport across the yeast plasma membrane
  publication-title: J. Biol. Chem.
– volume: 215
  start-page: 256
  year: 2017
  end-page: 268
  ident: bb0790
  article-title: The transporter SynPAM71 is located in the plasma membrane and thylakoids, and mediates manganese tolerance in Synechocystis PCC6803
  publication-title: New Phytol.
– volume: 77
  start-page: 521
  year: 2008
  end-page: 555
  ident: bb0110
  article-title: Glycosyltransferases: structures, functions, and mechanisms
  publication-title: Annu. Rev. Biochem.
– volume: 39
  start-page: 249
  year: 1973
  end-page: 326
  ident: bb0215
  article-title: The hexokinases: kinetic, physical, and regulatory properties
  publication-title: Adv. Enzymol. Relat. Areas Mol. Biol.
– volume: 22
  start-page: 2914
  year: 2013
  end-page: 2928
  ident: bb0805
  article-title: Impact of disease-causing mutations on TMEM165 subcellular localization, a recently identified protein involved in CDG-II
  publication-title: Hum. Mol. Genet.
– volume: 387
  start-page: 43
  year: 2017
  end-page: 56
  ident: bb0240
  article-title: Cobalt toxicity in humans-a review of the potential sources and systemic health effects
  publication-title: Toxicology
– year: 2007
  ident: bb0010
  article-title: Transport and Storage of Metal Ions in Biology
– volume: 19
  start-page: 1534
  year: 2019
  end-page: 6293
  ident: bb0425
  article-title: Genetic disorders of manganese metabolism
  publication-title: Curr. Neurol. Neurosci.
– volume: 9
  year: 2014
  ident: bb0770
  article-title: Molecular evolution of a novel family of putative calcium transporters
  publication-title: PLoS One
– volume: 108
  start-page: 858
  year: 2011
  end-page: 863
  ident: bb0505
  article-title: Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
– volume: 123
  start-page: 2148
  year: 2014
  end-page: 2152
  ident: bb0575
  article-title: XMEN disease: a new primary immunodeficiency affecting Mg2+ regulation of immunity against Epstein-Barr virus
  publication-title: Blood
– volume: 112
  start-page: 4268
  year: 2008
  end-page: 4275
  ident: bb0945
  article-title: Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2
  publication-title: Blood
– volume: 3
  start-page: 267
  year: 2011
  end-page: 270
  ident: bb0395
  article-title: Role of metal Dyshomeostasis in Alzheimer disease
  publication-title: Met. Integr. Biometal Sci.
– volume: 26
  start-page: 21
  year: 2016
  end-page: 29
  ident: bb0815
  article-title: TMEM165 deficiency: postnatal changes in glycosylation
  publication-title: JIMD Rep.
– volume: 34
  start-page: 118
  year: 2013
  end-page: 127
  ident: bb0650
  article-title: Manganese transport via the transferrin mechanism
  publication-title: Neurotoxicology
– volume: 414
  start-page: 170
  year: 2003
  end-page: 179
  ident: bb0210
  article-title: Phosphoenolpyruvate carboxylase: three-dimensional structure and molecular mechanisms
  publication-title: Arch. Biochem. Biophys.
– volume: 62
  start-page: 436
  year: 2010
  end-page: 446
  ident: bb0325
  article-title: Calnuc: emerging roles in calcium signaling and human diseases
  publication-title: IUBMB Life
– volume: 19
  start-page: 13
  year: 2004
  end-page: 25
  ident: bb0480
  article-title: Genetics of hereditary disorders of magnesium homeostasis
  publication-title: Pediatr. Nephrol. Berl. Ger.
– volume: 3
  start-page: 17025
  year: 2017
  ident: bb0600
  article-title: Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice
  publication-title: Cell Discov.
– volume: 31
  start-page: 1111
  year: 1999
  end-page: 1137
  ident: bb0645
  article-title: The transferrin receptor: role in health and disease
  publication-title: Int. J. Biochem. Cell Biol.
– volume: 165
  start-page: 123
  year: 2019
  end-page: 130
  ident: bb0905
  article-title: Dissection of TMEM165 function in Golgi glycosylation and its Mn2+ sensitivity
  publication-title: Biochimie
– volume: 62
  start-page: 227
  year: 1989
  end-page: 313
  ident: bb0220
  article-title: The phosphoglycerate mutases
  publication-title: Adv. Enzymol. Relat. Areas Mol. Biol.
– volume: 1
  start-page: 194
  year: 2010
  end-page: 203
  ident: bb0355
  article-title: Manganese accumulates within golgi apparatus in dopaminergic cells as revealed by synchrotron X-rayFluorescence nanoimaging
  publication-title: Cjem. Neurosci.
– volume: 7
  start-page: 11601
  year: 2016
  ident: bb0680
  article-title: Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia
  publication-title: Nat. Commun.
– volume: 272
  start-page: 23503
  year: 1997
  end-page: 23514
  ident: bb0120
  article-title: Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3
  publication-title: J. Biol. Chem.
– volume: 9
  start-page: 1149
  year: 1998
  end-page: 1162
  ident: bb0940
  article-title: The medial-Golgi ion pump Pmr1 supplies the yeast secretory pathway with Ca2+ and Mn2+ required for glycosylation, sorting, and endoplasmic reticulum-associated protein degradation
  publication-title: Mol. Biol. Cell
– volume: 21
  start-page: 271
  year: 1999
  end-page: 277
  ident: bb0485
  article-title: Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
  publication-title: Nat. Genet.
– volume: 287
  start-page: 13510
  year: 2012
  end-page: 13517
  ident: bb0370
  article-title: Metal transport across biomembranes: emerging models for a distinct chemistry
  publication-title: J. Biol. Chem.
– volume: 578
  start-page: 419
  year: 2020
  end-page: 424
  ident: bb0450
  article-title: ATP13A2 deficiency disrupts lysosomal polyamine export
  publication-title: Nature
– volume: 126
  start-page: 981
  year: 2006
  end-page: 993
  ident: bb0470
  article-title: Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer’s disease-linked mutations
  publication-title: Cell
– volume: 11
  start-page: 955
  year: 2018
  end-page: 969
  ident: bb0775
  article-title: The plastid envelope CHLOROPLAST MANGANESE TRANSPORTER1 is essential for manganese homeostasis in Arabidopsis
  publication-title: Mol. Plant
– volume: 21
  start-page: 1282
  year: 2010
  end-page: 1292
  ident: bb0440
  article-title: Manganese-induced trafficking and turnover of the cis-Golgi glycoprotein GPP130
  publication-title: Mol. Biol. Cell
– volume: 288
  start-page: 31963
  year: 2013
  end-page: 31970
  ident: bb0170
  article-title: Crystal structures of β-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding
  publication-title: J. Biol. Chem.
– volume: 12
  start-page: 169
  year: 2013
  end-page: 201
  ident: bb0275
  article-title: Manganese homeostasis and transport
  publication-title: Met. Ions Life Sci.
– volume: 291
  start-page: 14773
  year: 2016
  end-page: 14787
  ident: bb0430
  article-title: Direct comparison of manganese detoxification/efflux proteins and molecular characterization of ZnT10 protein as a manganese transporter
  publication-title: J. Biol. Chem.
– volume: 107
  start-page: 182
  year: 2009
  end-page: 193
  ident: bb0665
  article-title: Ceruloplasmin alters the tissue disposition and neurotoxicity of manganese, but not its loading onto transferrin
  publication-title: Toxicol. Sci.
– volume: 285
  start-page: 32141
  year: 2010
  end-page: 32150
  ident: bb0690
  article-title: ZRT/IRT-like protein 14 (ZIP14) promotes the cellular assimilation of iron from transferrin
  publication-title: J. Biol. Chem.
– volume: 109
  start-page: 4722
  year: 2009
  end-page: 4732
  ident: bb0740
  article-title: Manganese homeostasis in Saccharomyces cerevisiae
  publication-title: Chem. Rev.
– volume: 73
  start-page: 169
  year: 2016
  end-page: 193
  ident: bb0040
  article-title: The importance of magnesium in the human body: a systematic literature review
  publication-title: Adv. Clin. Chem.
– volume: 10
  start-page: 1514
  year: 2019
  end-page: 1521
  ident: bb0960
  article-title: A Golgi-targeting fluorescent probe for labile Fe(ii) to reveal an abnormal cellular iron distribution induced by dysfunction of VPS35
  publication-title: Chem. Sci.
– volume: 75
  start-page: 475
  year: 2019
  end-page: 487
  ident: bb0250
  article-title: Structural and functional insights into phosphomannose isomerase: the role of zinc and catalytic residues
  publication-title: Acta Crystallogr. Sect. Struct. Biol.
– volume: 13
  start-page: 81
  year: 2013
  end-page: 137
  ident: bb0265
  article-title: Calcium in health and disease
  publication-title: Met. Ions Life Sci.
– volume: 293
  start-page: 8048
  year: 2018
  end-page: 8055
  ident: bb0860
  article-title: The yeast protein Gdt1p transports Mn2+ ions and thereby regulates manganese homeostasis in the Golgi
  publication-title: J. Biol. Chem.
– volume: 7
  start-page: 3913
  year: 2017
  end-page: 3924
  ident: bb0870
  article-title: H
  publication-title: GenesGenomesGenetics
– reference: Arguello J., Lutsenko S., Metal Transporters, 1st ed., Academic Press, n.d.
– volume: 39
  start-page: 45
  year: 2006
  end-page: 57
  ident: bb0285
  article-title: Homeostatic and toxic mechanisms regulating manganese uptake, retention, and elimination
  publication-title: Biol. Res.
– volume: 7
  year: 2012
  ident: bb0100
  article-title: The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins
  publication-title: PLoS One
– volume: 71
  start-page: 3281
  year: 2014
  end-page: 3295
  ident: bb0510
  article-title: Current understanding of ZIP and ZnT zinc transporters in human health and diseases
  publication-title: Cell. Mol. Life Sci. CMLS
– volume: 257
  start-page: 9261
  year: 1982
  end-page: 9264
  ident: bb0365
  article-title: Determination of free and bound manganese(II) in hepatocytes from fed and faster rats
  publication-title: J. Biol. Chem.
– volume: 272
  start-page: 30873
  year: 1997
  end-page: 30879
  ident: bb0310
  article-title: BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+
  publication-title: J. Biol. Chem.
– volume: 8
  year: 2013
  ident: bb0720
  article-title: The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum
  publication-title: PLoS One
– volume: 293
  start-page: 5715
  year: 2018
  end-page: 5730
  ident: bb0785
  article-title: Structure-function analysis of manganese exporter proteins across bacteria
  publication-title: J. Biol. Chem.
– volume: 18
  start-page: 144
  year: 2013
  end-page: 157
  ident: bb0235
  article-title: Zinc and its importance for human health: an integrative review
  publication-title: J. Res. Med. Sci. Off. J. Isfahan Univ. Med. Sci.
– volume: 116
  start-page: 9865
  year: 2019
  end-page: 9870
  ident: bb0565
  article-title: Mutations in MAGT1 lead to a glycosylation disorder with a variable phenotype
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
– volume: 9
  start-page: 1131
  year: 2000
  end-page: 1140
  ident: bb0490
  article-title: Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump
  publication-title: Hum. Mol. Genet.
– volume: 28
  start-page: 2569
  year: 2017
  end-page: 2578
  ident: bb0875
  article-title: Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin
  publication-title: Mol. Biol. Cell
– volume: 100
  start-page: 216
  year: 2017
  end-page: 227
  ident: bb0830
  article-title: Mutations in ATP6V1E1 or ATP6V1A cause autosomal-recessive cutis Laxa
  publication-title: Am. J. Hum. Genet.
– volume: 34
  start-page: 441
  year: 1993
  end-page: 446
  ident: bb0080
  article-title: Manganese and epilepsy: brain glutamine synthetase and liver arginase activities in genetically epilepsy prone and chronically seizured rats
  publication-title: Epilepsia
– volume: 1465
  start-page: 190
  year: 2000
  end-page: 198
  ident: bb0670
  article-title: The ZIP family of metal transporters
  publication-title: Biochim. Biophys. Acta
– volume: 40
  start-page: 8765
  year: 2001
  end-page: 8772
  ident: bb0190
  article-title: Independent Lec1A CHO glycosylation mutants arise from point mutations in N-acetylglucosaminyltransferase I that reduce affinity for both substrates molecular consequences based on the crystal structure of GlcNAc-TI
  publication-title: Biochemistry
– volume: 37
  start-page: 587
  year: 2000
  end-page: 611
  ident: bb0060
  article-title: Manganese superoxide dismutase
  publication-title: Met. Ions Biol. Syst.
– volume: 206
  start-page: 635
  year: 2014
  end-page: 654
  ident: bb0755
  article-title: Cofilin recruits F-actin to SPCA1 and promotes Ca2+−mediated secretory cargo sorting
  publication-title: J. Cell Biol.
– volume: 25
  start-page: 669
  year: 2015
  end-page: 682
  ident: bb0820
  article-title: Abnormal cartilage development and altered N-glycosylation in Tmem165-deficient zebrafish mirrors the phenotypes associated with TMEM165-CDG
  publication-title: Glycobiology
– volume: 110
  start-page: 6859
  year: 2013
  end-page: 6864
  ident: bb0765
  article-title: Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells
  publication-title: Proc. Natl. Acad. Sci.
– volume: 476
  start-page: 3281
  year: 2019
  end-page: 3293
  ident: bb0925
  article-title: Investigating the functional link between TMEM165 and SPCA1
  publication-title: Biochem. J.
– volume: 98
  start-page: 322
  year: 2016
  end-page: 330
  ident: bb0835
  article-title: TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation
  publication-title: Am. J. Hum. Genet.
– volume: 474
  start-page: 1481
  year: 2017
  end-page: 1493
  ident: bb0880
  article-title: Manganese-induced turnover of TMEM165
  publication-title: Biochem. J.
– volume: 4
  start-page: 551
  year: 1994
  end-page: 566
  ident: bb0245
  article-title: Mammalian alpha-mannosidases--multiple forms but a common purpose?
  publication-title: Glycobiology
– volume: 2003
  start-page: 7047
  year: 2019
  end-page: 7061
  ident: bb0360
  article-title: Emerging chemical tools and techniques for tracking biological manganese
  publication-title: Dalton Trans. Camb. Engl.
– volume: 91
  start-page: 15
  year: 2012
  end-page: 26
  ident: bb0555
  article-title: TMEM165 deficiency causes a congenital disorder of glycosylation
  publication-title: Am. J. Hum. Genet.
– volume: 8
  start-page: 145
  year: 2013
  end-page: 152
  ident: bb0840
  article-title: Bone dysplasia as a key feature in three patients with a novel congenital disorder of glycosylation (CDG) type II due to a deep Intronic splice mutation in TMEM165
  publication-title: JIMD Rep.
– volume: 13
  start-page: 484
  year: 2004
  end-page: 490
  ident: bb0090
  article-title: In vitro induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 expression in keratinocytes by boron and manganese
  publication-title: Exp. Dermatol.
– volume: 58
  start-page: 730
  year: 1992
  end-page: 735
  ident: bb0350
  article-title: Manganese uptake and efflux in cultured rat astrocytes
  publication-title: J. Neurochem.
– volume: 130
  start-page: 4604
  year: 2008
  end-page: 4606
  ident: bb0065
  article-title: Manganous phosphate acts as a superoxide dismutase
  publication-title: J. Am. Chem. Soc.
– volume: 24
  start-page: 159
  year: 2011
  end-page: 170
  ident: bb0500
  article-title: Vesicular distribution of secretory pathway Ca2+-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells
  publication-title: Biometals Int. J. Role Met. Ions Biol. Biochem. Med.
– volume: 1131
  start-page: 183
  year: 2020
  end-page: 213
  ident: bb0020
  article-title: An update to calcium binding proteins
  publication-title: Adv. Exp. Med. Biol.
– volume: 112
  start-page: 1190
  year: 2010
  end-page: 1198
  ident: bb0705
  article-title: Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation
  publication-title: J. Neurochem.
– volume: 39
  start-page: 2149
  year: 2000
  end-page: 2163
  ident: bb0195
  article-title: Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity
  publication-title: Biochemistry
– volume: 3
  year: 2014
  ident: bb0125
  article-title: The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation
  publication-title: ELife
– volume: 18
  start-page: 2242
  year: 2009
  end-page: 2251
  ident: bb0260
  article-title: Human lysosomal alpha-mannosidases exhibit different inhibition and metal binding properties
  publication-title: Protein Sci. Publ. Protein Soc.
– volume: 400
  start-page: 33
  year: 2006
  end-page: 41
  ident: bb0255
  article-title: Man2C1, an alpha-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol
  publication-title: Biochem. J.
– volume: 173
  start-page: 1798
  year: 2017
  end-page: 1810
  ident: bb0795
  article-title: The Synechocystis manganese exporter Mnx is essential for manganese homeostasis in cyanobacteria
  publication-title: Plant Physiol.
– volume: 19
  year: 2017
  ident: bb0900
  article-title: Acidic and uncharged polar residues in the consensus motifs of the yeast Ca2+transporter Gdt1p are required for calcium transport
  publication-title: Cell. Microbiol
– volume: 50
  start-page: 184
  year: 2011
  end-page: 192
  ident: bb0295
  article-title: Ca(2+) signalling in the Golgi apparatus
  publication-title: Cell Calcium
– volume: 15
  start-page: 303
  year: 1992
  end-page: 308
  ident: bb0335
  article-title: Calcium-binding proteins in the nervous system
  publication-title: Trends Neurosci.
– volume: 3
  year: 2011
  ident: bb0745
  article-title: The Ca2+ pumps of the endoplasmic reticulum and golgi apparatus
  publication-title: Cold Spring Harb. Perspect. Biol.
– volume: 445
  start-page: 417
  year: 2014
  end-page: 421
  ident: bb0895
  article-title: The Ca(2+)/H(+) antiporter TMEM165 expression, localization in the developing, lactating and involuting mammary gland parallels the secretory pathway Ca(2+) ATPase (SPCA1)
  publication-title: Biochem. Biophys. Res. Commun.
– volume: 81
  start-page: 87
  year: 2002
  end-page: 100
  ident: bb0330
  article-title: The calcium-binding protein p54/NEFA is a novel luminal resident of medial Golgi cisternae that traffics independently of mannosidase II
  publication-title: Eur. J. Cell Biol.
– volume: 1993
  start-page: 277
  year: 1997
  end-page: 289
  ident: bb0035
  article-title: Structure of a human lysosomal sulfatase
  publication-title: Struct. Lond. Engl.
– volume: 117
  start-page: 169
  year: 2010
  end-page: 179
  ident: bb0390
  article-title: Altered manganese homeostasis and manganese toxicity in a Huntington’s disease striatal cell model are not explained by defects in the iron transport system
  publication-title: Toxicol. Sci. Off. J. Soc. Toxicol.
– volume: 169
  start-page: 374
  year: 2018
  end-page: 382
  ident: bb0590
  article-title: Mn2+ dynamics in manganese-enhanced MRI (MEMRI): Cav12 channel-mediated uptake and preferential accumulation in projection terminals
  publication-title: NeuroImage
– volume: 4
  start-page: 435
  year: 2014
  end-page: 457
  ident: bb0290
  article-title: Metallothioneins, unconventional proteins from unconventional animals: a long journey from nematodes to mammals
  publication-title: Biomolecules
– volume: 11
  start-page: 1315
  year: 2010
  end-page: 1333
  ident: bb0735
  article-title: The SPCA1 Ca2+ pump and intracellular membrane trafficking
  publication-title: Traffic
– volume: 329
  start-page: 139
  year: 2014
  end-page: 147
  ident: bb0105
  article-title: The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes
  publication-title: Exp. Cell Res.
– volume: 282
  start-page: 9564
  year: 2007
  end-page: 9570
  ident: bb0150
  article-title: Structural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motif
  publication-title: J. Biol. Chem.
– volume: 590
  start-page: 2086
  year: 2016
  end-page: 2095
  ident: bb0725
  article-title: Mn(2+) transport by Ca(2+) -ATPase of sarcoplasmic reticulum
  publication-title: FEBS Lett.
– volume: 1861
  start-page: 737
  year: 2017
  end-page: 748
  ident: bb0810
  article-title: Evidence for splice transcript variants of TMEM165, a gene involved in CDG
  publication-title: Biochim. Biophys. Acta BBA - Gen. Subj.
– volume: 82
  start-page: 1158
  year: 2008
  end-page: 1164
  ident: bb0570
  article-title: A defect in the TUSC3 gene is associated with autosomal recessive mental retardation
  publication-title: Am. J. Hum. Genet.
– volume: 7
  start-page: 389
  year: 2007
  end-page: 396
  ident: bb0535
  article-title: Congenital disorders of glycosylation: CDG-I, CDG-II, and beyond
  publication-title: Curr. Mol. Med.
– volume: 54
  start-page: 1065
  year: 1991
  end-page: 1070
  ident: bb0635
  article-title: The effect of individual dietary components on manganese absorption in humans
  publication-title: Am. J. Clin. Nutr.
– volume: 11
  start-page: 711
  year: 2001
  end-page: 717
  ident: bb0180
  article-title: Production of soluble human alpha3-fucosyltransferase (FucT VII) by membrane targeting and in vivo proteolysis
  publication-title: Glycobiology
– volume: 1742
  start-page: 103
  year: 2004
  end-page: 112
  ident: bb0025
  article-title: The Ca2+/Mn2+ pumps in the Golgi apparatus
  publication-title: Biochim. Biophys. Acta
– volume: 278
  start-page: 30235
  year: 2003
  end-page: 30247
  ident: bb0160
  article-title: Chondroitin sulfate synthase-2 molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities
  publication-title: J. Biol. Chem.
– volume: 1862
  start-page: 394
  year: 2018
  end-page: 402
  ident: bb0930
  article-title: Investigating the function of Gdt1p in yeast Golgi glycosylation
  publication-title: Biochim. Biophys. Acta BBA - Gen. Subj.
– volume: 17
  start-page: 35
  year: 2004
  end-page: 43
  ident: bb0140
  article-title: Effect of the manganese ion on human alpha3/4 fucosyltransferase III activity
  publication-title: Biometals Int. J. Role Met. Ions Biol. Biochem. Med.
– volume: 466
  start-page: 11
  year: 2000
  end-page: 18
  ident: bb0320
  article-title: The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cells
  publication-title: FEBS Lett.
– volume: 4
  year: 2009
  ident: bb0515
  article-title: Evolutionary descent of prion genes from the ZIP family of metal ion transporters
  publication-title: PLoS One
– volume: 45
  start-page: 295
  year: 2020
  end-page: 307
  ident: bb0545
  article-title: Structure and roles of V-type ATPases
  publication-title: Trends Biochem. Sci.
– volume: 41
  start-page: 57
  year: 2016
  end-page: 65
  ident: bb0580
  article-title: N-linked glycosylation and homeostasis of the endoplasmic reticulum
  publication-title: Curr. Opin. Cell Biol.
– volume: 460
  start-page: 823
  year: 2009
  end-page: 830
  ident: bb0005
  article-title: Metalloproteins and metal sensing
  publication-title: Nature
– volume: 151
  start-page: 69
  year: 1977
  end-page: 76
  ident: bb0420
  article-title: Manganese mutagenesis in yeast VI Mn2+ uptake, mitDNA replication and ER induction: comparison with other divalent cations
  publication-title: Mol. Gen. Genet. MGG
– volume: 23
  start-page: 1655
  year: 2018
  end-page: 1679
  ident: bb0620
  article-title: Manganese metabolism in humans
  publication-title: Front. Biosci. Landmark Ed.
– volume: 442
  start-page: 178
  year: 2013
  end-page: 185
  ident: bb0845
  article-title: Serum N-glycan and O-glycan analysis by mass spectrometry for diagnosis of congenital disorders of glycosylation
  publication-title: Anal. Biochem.
– volume: 29
  start-page: 466
  year: 2008
  end-page: 470
  ident: bb0340
  article-title: Manganese accumulates primarily in nuclei of cultured brain cells
  publication-title: Neurotoxicology
– volume: 18
  year: 2017
  ident: bb0675
  article-title: Recent advances in the role of SLC39A/ZIP zinc transporters In vivo
  publication-title: Int. J. Mol. Sci
– volume: 17
  year: 2016
  ident: bb0410
  article-title: Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies
  publication-title: BMC Pharmacol. Toxicol
– volume: 29
  start-page: 569
  year: 2008
  end-page: 576
  ident: bb0640
  article-title: Manganese transport in eukaryotes: the role of DMT1
  publication-title: Neurotoxicology
– volume: 294
  start-page: 9147
  year: 2019
  end-page: 9160
  ident: bb0685
  article-title: The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis
  publication-title: J. Biol. Chem.
– volume: 97
  start-page: 894
  year: 2015
  end-page: 903
  ident: bb0560
  article-title: SLC39A8 deficiency: a disorder of manganese transport and glycosylation
  publication-title: Am. J. Hum. Genet.
– volume: 217
  start-page: 179
  year: 2018
  end-page: 193
  ident: bb0955
  article-title: NRAMP2, a trans-Golgi network-localized manganese transporter, is required for Arabidopsis root growth under manganese deficiency
  publication-title: New Phytol.
– volume: 14
  start-page: 593
  year: 2004
  end-page: 600
  ident: bb0115
  article-title: Structure and catalytic cycle of beta-1,4-galactosyltransferase
  publication-title: Curr. Opin. Struct. Biol.
– volume: 35
  start-page: 71
  year: 2015
  end-page: 108
  ident: bb0070
  article-title: Manganese is essential for neuronal health
  publication-title: Annu. Rev. Nutr.
– volume: 25
  start-page: 1489
  year: 2016
  end-page: 1500
  ident: bb0760
  article-title: Glycosylation abnormalities in Gdt1p/TMEM165 deficient cells result from a defect in Golgi manganese homeostasis
  publication-title: Hum. Mol. Genet.
– volume: 35
  start-page: 195
  year: 2007
  end-page: 202
  ident: bb0465
  article-title: Searching for a role of NCX/NCKX exchangers in neurodegeneration
  publication-title: Mol. Neurobiol.
– volume: 177
  start-page: 637
  year: 2007
  end-page: 645
  ident: bb0230
  article-title: Zinc is a novel intracellular second messenger
  publication-title: J. Cell Biol.
– volume: 13
  start-page: 1045
  year: 2014
  end-page: 1060
  ident: bb0400
  article-title: The role of iron in brain ageing and neurodegenerative disorders
  publication-title: Lancet Neurol.
– volume: 10
  start-page: 15
  year: 1999
  end-page: 24
  ident: bb0615
  article-title: Manganese deficiency and toxicity: are high or low dietary amounts of manganese cause for concern?
  publication-title: BioFactors Oxf. Engl.
– volume: 9
  start-page: 1028
  year: 2017
  end-page: 1046
  ident: bb0630
  article-title: Influence of iron metabolism on manganese transport and toxicity
  publication-title: Met. Integr. Biometal Sci.
– volume: 28
  start-page: 892
  year: 2016
  end-page: 910
  ident: bb0800
  article-title: The evolutionarily conserved protein PHOTOSYNTHESIS AFFECTED MUTANT71 is required for efficient manganese uptake at the thylakoid membrane in Arabidopsis
  publication-title: Plant Cell
– volume: 119
  start-page: 1461
  year: 1989
  end-page: 1464
  ident: bb0655
  article-title: Identification of transferrin as the major plasma carrier protein for manganese introduced orally or intravenously or after in vitro addition in the rat
  publication-title: J. Nutr.
– volume: 134
  start-page: 601
  year: 2015
  end-page: 610
  ident: bb0660
  article-title: Manganese homeostasis in the nervous system
  publication-title: J. Neurochem.
– volume: 120
  start-page: 1002
  year: 1996
  end-page: 1006
  ident: bb0135
  article-title: Detection of UDP-D-xylose: alpha-D-xyloside alpha 1-->3xylosyltransferase activity in human hepatoma cell line HepG2
  publication-title: J. Biochem. (Tokyo)
– volume: 11
  start-page: 153
  year: 2008
  end-page: 160
  ident: bb0075
  article-title: Nutritional control via Tor signaling in
  publication-title: Curr. Opin. Microbiol.
– volume: 17
  start-page: 529
  year: 2003
  end-page: 546
  ident: bb0475
  article-title: Disorders of calcium homeostasis
  publication-title: Best Pract. Res. Clin. Endocrinol. Metab.
– volume: 266
  start-page: 7155
  year: 1991
  end-page: 7165
  ident: bb0315
  article-title: Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum
  publication-title: J. Biol. Chem.
– volume: 34
  start-page: 14079
  year: 2014
  end-page: 14095
  ident: bb0435
  article-title: SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity
  publication-title: J. Neurosci.
– volume: 278
  start-page: 39711
  year: 2003
  end-page: 39725
  ident: bb0165
  article-title: Chondroitin sulfate synthase-3 molecular cloning and characterization
  publication-title: J. Biol. Chem.
– volume: 282
  start-page: 35646
  year: 2007
  end-page: 35656
  ident: bb0605
  article-title: Evolution of differences in transport function in Slc11a family members
  publication-title: J. Biol. Chem.
– volume: 5
  start-page: 33
  year: 2013
  ident: bb0460
  article-title: Zinc homeostasis and neurodegenerative disorders
  publication-title: Front. Aging Neurosci.
– volume: 1792
  start-page: 896
  year: 2009
  end-page: 902
  ident: bb0825
  article-title: COG defects, birth and rise!
  publication-title: Biochim. Biophys. Acta
– volume: 87
  start-page: S169
  year: 2002
  end-page: S177
  ident: bb0015
  article-title: Calcium intake, calcium bioavailability and bone health
  publication-title: Br. J. Nutr.
– volume: 75
  start-page: 59
  year: 1987
  end-page: 64
  ident: bb0385
  article-title: Metal toxicity in the central nervous system
  publication-title: Environ. Health Perspect.
– volume: 663
  start-page: 66
  year: 2018
  end-page: 71
  ident: bb0455
  article-title: The PMR1 pump in alpha-synuclein toxicity and neurodegeneration
  publication-title: Neurosci. Lett.
– volume: 6
  year: 2014
  ident: bb0950
  article-title: Retromer: a master conductor of endosome sorting
  publication-title: Cold Spring Harb. Perspect. Biol
– volume: 14
  start-page: 3482
  year: 2003
  end-page: 3493
  ident: bb0185
  article-title: Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum
  publication-title: Mol. Biol. Cell
– volume: 16
  year: 2019
  ident: bb0405
  article-title: New insights on the role of manganese in Alzheimer’s Disease and Parkinson’s Disease
  publication-title: Int. J. Environ. Res. Public. Health
– volume: 295
  start-page: 3865
  year: 2020
  end-page: 3874
  ident: bb0885
  article-title: The human Golgi protein TMEM165 transports calcium and manganese in yeast and bacterial cells
  publication-title: J. Biol. Chem.
– volume: 322
  start-page: 1204
  year: 2004
  end-page: 1213
  ident: bb0495
  article-title: SPCA1 pumps and Hailey-Hailey disease
  publication-title: Biochem. Biophys. Res. Commun.
– volume: 60
  start-page: 439
  year: 2011
  end-page: 452
  ident: bb0300
  article-title: Calsequestrin distribution, structure and function, its role in normal and pathological situations and the effect of thyroid hormones
  publication-title: Physiol. Res.
– volume: 294
  start-page: 7878
  year: 2019
  end-page: 7891
  ident: bb0910
  article-title: An N-terminal Ca2+−binding motif regulates the secretory pathway Ca2+/Mn2+−transport ATPase SPCA1
  publication-title: J. Biol. Chem.
– volume: 65
  start-page: 2039
  year: 2008
  end-page: 2055
  ident: bb0225
  article-title: Evolution of the arginase fold and functional diversity
  publication-title: Cell. Mol. Life Sci. CMLS
– reference: Zheng J, Trudeau M.C., Handbook of Ion Channels, CRC Press, n.d.
– volume: 33
  start-page: 2669
  year: 2019
  end-page: 2679
  ident: bb0935
  article-title: Involvement of thapsigargin and cyclopiazonic acid-sensitive pumps in the rescue of TMEM165-associated glycosylation defects by Mn2
  publication-title: FASEB J.
– volume: 2014
  year: 2014
  ident: bb0445
  article-title: Mutations in the ATP13A2 gene and Parkinsonism: a preliminary review
  publication-title: Biomed. Res. Int.
– volume: 26
  start-page: 1252
  year: 2011
  end-page: 1260
  ident: bb0095
  article-title: Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone
  publication-title: J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res.
– volume: 102
  start-page: 1884
  year: 2003
  end-page: 1892
  ident: bb0595
  article-title: Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane
  publication-title: Blood
– volume: 1993
  start-page: 853
  year: 1995
  end-page: 859
  ident: bb0030
  article-title: Structures and mechanisms of glycosyl hydrolases
  publication-title: Struct. Lond. Engl.
– volume: 49
  start-page: 150
  year: 2017
  end-page: 156
  ident: bb0715
  article-title: TMEM165 deficiencies in congenital disorders of glycosylation type II (CDG-II): clues and evidences for roles of the protein in Golgi functions and ion homeostasis
  publication-title: Tissue Cell
– volume: 14
  start-page: 1129
  year: 1989
  end-page: 1135
  ident: bb0345
  article-title: Manganese(II) dynamics and distribution in glial cells cultured from chick cerebral cortex
  publication-title: Neurochem. Res.
– volume: 386
  start-page: 227
  year: 2005
  end-page: 236
  ident: bb0155
  article-title: Human xylosyltransferase I: functional and biochemical characterization of cysteine residues required for enzymic activity
  publication-title: Biochem. J.
– volume: 69
  start-page: 249
  year: 2012
  end-page: 293
  ident: bb0610
  article-title: Nramp: from sequence to structure and mechanism of divalent metal import
  publication-title: Curr. Top. Membr.
– volume: 127
  start-page: 2407
  year: 2017
  end-page: 2417
  ident: bb0695
  article-title: Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity
  publication-title: J. Clin. Invest.
– volume: 102
  start-page: 1375
  year: 2017
  end-page: 1386
  ident: bb0855
  article-title: Galactose supplementation in patients with TMEM165-CDG rescues the glycosylation defects
  publication-title: J. Clin. Endocrinol. Metab.
– volume: 46
  start-page: 111
  year: 1981
  end-page: 118
  ident: bb0270
  article-title: Zinc transport proteins in plasma
  publication-title: Br. J. Nutr.
– volume: 63
  start-page: 843
  year: 2006
  end-page: 854
  ident: bb0205
  article-title: Anaplerotic roles of pyruvate carboxylase in mammalian tissues
  publication-title: Cell. Mol. Life Sci. CMLS
– volume: 280
  start-page: 11608
  year: 2005
  end-page: 11614
  ident: bb0750
  article-title: A novel isoform of the secretory pathway Ca2+,Mn(2+)-ATPase, hSPCA2, has unusual properties and is expressed in the brain
  publication-title: J. Biol. Chem.
– volume: 275
  start-page: 40498
  year: 2000
  end-page: 40503
  ident: bb0175
  article-title: Expression cloning of human globoside synthase cDNAs identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase
  publication-title: J. Biol. Chem.
– volume: 1979
  start-page: 252
  year: 2008
  end-page: 258
  ident: bb0085
  article-title: Role of bradykinin, nitric oxide, and angiotensin II type 2 receptor in imidapril-induced angiogenesis, Hypertens
  publication-title: Dallas Tex
– volume: 1763
  start-page: 609
  year: 2006
  end-page: 620
  ident: bb0540
  article-title: The NRAMP family of metal-ion transporters
  publication-title: Biochim. Biophys. Acta
– volume: 113
  start-page: 313
  year: 2010
  end-page: 328
  ident: bb0585
  article-title: TRP channels of intracellular membranes
  publication-title: J. Neurochem.
– volume: 6
  start-page: 24282
  year: 2016
  ident: bb0850
  article-title: Yeast Gdt1 is a Golgi-localized calcium transporter required for stress-induced calcium signaling and protein glycosylation
  publication-title: Sci. Rep.
– volume: 311
  start-page: 53
  year: 2001
  end-page: 56
  ident: bb0415
  article-title: Manganese mimics the action of 1-methyl-4-phenylpyridinium ion, a dopaminergic neurotoxin, in rat striatal tissue slices
  publication-title: Neurosci. Lett.
– volume: 289
  start-page: 28138
  year: 2014
  end-page: 28148
  ident: bb0200
  article-title: Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues
  publication-title: J. Biol. Chem.
– volume: 444
  start-page: 1
  year: 1976
  end-page: 10
  ident: bb0280
  article-title: Manganese metabolism in cows and goats
  publication-title: Biochim. Biophys. Acta
– volume: 13
  year: 2018
  ident: bb0730
  article-title: Parkinson disease related ATP13A2 evolved early in animal evolution
  publication-title: PLoS One
– volume: 8
  start-page: 261
  year: 2007
  end-page: 278
  ident: bb0530
  article-title: Congenital disorders of glycosylation: a rapidly expanding disease family
  publication-title: Annu. Rev. Genomics Hum. Genet.
– volume: 92
  start-page: 3103
  year: 2020
  end-page: 3110
  ident: bb0865
  article-title: In situ fluorescent and photoacoustic imaging of Golgi pH to elucidate the function of transmembrane protein 165
  publication-title: Anal. Chem.
– volume: 60
  start-page: 949
  year: 1994
  end-page: 955
  ident: bb0625
  article-title: Sex affects manganese absorption and retention by humans from a diet adequate in manganese
  publication-title: Am. J. Clin. Nutr.
– volume: 110
  start-page: 277
  year: 2013
  end-page: 312
  ident: bb0055
  article-title: Manganese and the brain
  publication-title: Int. Rev. Neurobiol.
– volume: 9
  year: 2020
  ident: bb0780
  article-title: Homologous Proteins of the Manganese Transporter PAM71 Are Localized in the Golgi Apparatus and Endoplasmic Reticulum
  publication-title: Plants Basel Switz
– volume: 101
  start-page: 251
  year: 1987
  end-page: 259
  ident: bb0145
  article-title: Identification and characterization of UDP-GalNAc: NeuAc alpha 2-3Gal beta 1-4Glc(NAc) beta 1-4(GalNAc to Gal)N-acetylgalactosaminyltransferase in human blood plasma
  publication-title: J. Biochem. (Tokyo)
– volume: 40
  start-page: 32
  year: 2008
  end-page: 34
  ident: bb0550
  article-title: Impaired glycosylation and cutis laxa caused by mutations in the vesicular H+-ATPase subunit ATP6V0A2
  publication-title: Nat. Genet.
– volume: 20
  start-page: 445
  year: 1999
  end-page: 453
  ident: bb0710
  article-title: Manganese and calcium transport in mitochondria: implications for manganese toxicity
  publication-title: Neurotoxicology
– volume: 61
  start-page: 643
  year: 2018
  end-page: 663
  ident: bb0525
  article-title: Congenital disorders of glycosylation (CDG): Quo vadis?
  publication-title: Eur. J. Med. Genet.
– volume: 8
  start-page: 3163
  year: 2018
  ident: bb0700
  article-title: Functional analysis of SLC39A8 mutations and their implications for manganese deficiency and mitochondrial disorders
  publication-title: Sci. Rep.
– volume: 28
  start-page: R1403
  year: 2018
  end-page: R1405
  ident: bb0050
  article-title: Signal transduction: magnesium manifests as a second messenger
  publication-title: Curr. Biol. CB
– volume: 119
  start-page: 615
  year: 2006
  end-page: 623
  ident: bb0305
  article-title: Beyond lectins: the calnexin/calreticulin chaperone system of the endoplasmic reticulum
  publication-title: J. Cell Sci.
– volume: 294
  start-page: 3181
  year: 2019
  end-page: 3191
  ident: bb0890
  article-title: Milk biosynthesis requires the Golgi cation exchanger TMEM165
  publication-title: J. Biol. Chem.
– volume: 63
  start-page: 843
  year: 2006
  ident: 10.1016/j.bbagen.2020.129674_bb0205
  article-title: Anaplerotic roles of pyruvate carboxylase in mammalian tissues
  publication-title: Cell. Mol. Life Sci. CMLS
  doi: 10.1007/s00018-005-5410-y
– volume: 414
  start-page: 170
  year: 2003
  ident: 10.1016/j.bbagen.2020.129674_bb0210
  article-title: Phosphoenolpyruvate carboxylase: three-dimensional structure and molecular mechanisms
  publication-title: Arch. Biochem. Biophys.
  doi: 10.1016/S0003-9861(03)00170-X
– volume: 9
  start-page: 1149
  year: 1998
  ident: 10.1016/j.bbagen.2020.129674_bb0940
  article-title: The medial-Golgi ion pump Pmr1 supplies the yeast secretory pathway with Ca2+ and Mn2+ required for glycosylation, sorting, and endoplasmic reticulum-associated protein degradation
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.9.5.1149
– volume: 13
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0730
  article-title: Parkinson disease related ATP13A2 evolved early in animal evolution
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0193228
– volume: 98
  start-page: 322
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0835
  article-title: TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation
  publication-title: Am. J. Hum. Genet.
  doi: 10.1016/j.ajhg.2015.12.011
– volume: 1792
  start-page: 896
  year: 2009
  ident: 10.1016/j.bbagen.2020.129674_bb0825
  article-title: COG defects, birth and rise!
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbadis.2008.10.020
– volume: 82
  start-page: 1158
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0570
  article-title: A defect in the TUSC3 gene is associated with autosomal recessive mental retardation
  publication-title: Am. J. Hum. Genet.
  doi: 10.1016/j.ajhg.2008.03.018
– year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0920
– volume: 12
  start-page: 169
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0275
  article-title: Manganese homeostasis and transport
  publication-title: Met. Ions Life Sci.
  doi: 10.1007/978-94-007-5561-1_6
– volume: 108
  start-page: 858
  year: 2011
  ident: 10.1016/j.bbagen.2020.129674_bb0505
  article-title: Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1013642108
– volume: 215
  start-page: 256
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0790
  article-title: The transporter SynPAM71 is located in the plasma membrane and thylakoids, and mediates manganese tolerance in Synechocystis PCC6803
  publication-title: New Phytol.
  doi: 10.1111/nph.14526
– volume: 28
  start-page: R1403
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0050
  article-title: Signal transduction: magnesium manifests as a second messenger
  publication-title: Curr. Biol. CB
  doi: 10.1016/j.cub.2018.11.003
– volume: 25
  start-page: 1489
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0760
  article-title: Glycosylation abnormalities in Gdt1p/TMEM165 deficient cells result from a defect in Golgi manganese homeostasis
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/ddw026
– volume: 91
  start-page: 15
  year: 2012
  ident: 10.1016/j.bbagen.2020.129674_bb0555
  article-title: TMEM165 deficiency causes a congenital disorder of glycosylation
  publication-title: Am. J. Hum. Genet.
  doi: 10.1016/j.ajhg.2012.05.002
– volume: 13
  start-page: 1045
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0400
  article-title: The role of iron in brain ageing and neurodegenerative disorders
  publication-title: Lancet Neurol.
  doi: 10.1016/S1474-4422(14)70117-6
– volume: 289
  start-page: 28138
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0200
  article-title: Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M114.597831
– volume: 16
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0405
  article-title: New insights on the role of manganese in Alzheimer’s Disease and Parkinson’s Disease
  publication-title: Int. J. Environ. Res. Public. Health
  doi: 10.3390/ijerph16193546
– volume: 107
  start-page: 182
  year: 2009
  ident: 10.1016/j.bbagen.2020.129674_bb0665
  article-title: Ceruloplasmin alters the tissue disposition and neurotoxicity of manganese, but not its loading onto transferrin
  publication-title: Toxicol. Sci.
  doi: 10.1093/toxsci/kfn231
– volume: 272
  start-page: 23503
  year: 1997
  ident: 10.1016/j.bbagen.2020.129674_bb0120
  article-title: Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.272.38.23503
– volume: 217
  start-page: 179
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0955
  article-title: NRAMP2, a trans-Golgi network-localized manganese transporter, is required for Arabidopsis root growth under manganese deficiency
  publication-title: New Phytol.
  doi: 10.1111/nph.14783
– volume: 29
  start-page: 569
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0640
  article-title: Manganese transport in eukaryotes: the role of DMT1
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2008.04.022
– volume: 17
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0410
  article-title: Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies
  publication-title: BMC Pharmacol. Toxicol
  doi: 10.1186/s40360-016-0099-0
– volume: 25
  start-page: 669
  year: 2015
  ident: 10.1016/j.bbagen.2020.129674_bb0820
  article-title: Abnormal cartilage development and altered N-glycosylation in Tmem165-deficient zebrafish mirrors the phenotypes associated with TMEM165-CDG
  publication-title: Glycobiology
  doi: 10.1093/glycob/cwv009
– volume: 134
  start-page: 601
  year: 2015
  ident: 10.1016/j.bbagen.2020.129674_bb0660
  article-title: Manganese homeostasis in the nervous system
  publication-title: J. Neurochem.
  doi: 10.1111/jnc.13170
– volume: 54
  start-page: 1065
  year: 1991
  ident: 10.1016/j.bbagen.2020.129674_bb0635
  article-title: The effect of individual dietary components on manganese absorption in humans
  publication-title: Am. J. Clin. Nutr.
  doi: 10.1093/ajcn/54.6.1065
– volume: 2003
  start-page: 7047
  issue: 48
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0360
  article-title: Emerging chemical tools and techniques for tracking biological manganese
  publication-title: Dalton Trans. Camb. Engl.
  doi: 10.1039/C9DT00508K
– year: 2011
  ident: 10.1016/j.bbagen.2020.129674_bb0045
  article-title: Intracellular magnesium homeostasis
– volume: 173
  start-page: 1798
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0795
  article-title: The Synechocystis manganese exporter Mnx is essential for manganese homeostasis in cyanobacteria
  publication-title: Plant Physiol.
  doi: 10.1104/pp.16.01895
– volume: 5
  start-page: 33
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0460
  article-title: Zinc homeostasis and neurodegenerative disorders
  publication-title: Front. Aging Neurosci.
  doi: 10.3389/fnagi.2013.00033
– volume: 282
  start-page: 35646
  year: 2007
  ident: 10.1016/j.bbagen.2020.129674_bb0605
  article-title: Evolution of differences in transport function in Slc11a family members
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M707057200
– volume: 3
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0125
  article-title: The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation
  publication-title: ELife
  doi: 10.7554/eLife.03941
– volume: 123
  start-page: 2148
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0575
  article-title: XMEN disease: a new primary immunodeficiency affecting Mg2+ regulation of immunity against Epstein-Barr virus
  publication-title: Blood
  doi: 10.1182/blood-2013-11-538686
– volume: 278
  start-page: 30235
  year: 2003
  ident: 10.1016/j.bbagen.2020.129674_bb0160
  article-title: Chondroitin sulfate synthase-2 molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M303657200
– volume: 1763
  start-page: 609
  year: 2006
  ident: 10.1016/j.bbagen.2020.129674_bb0540
  article-title: The NRAMP family of metal-ion transporters
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbamcr.2006.05.007
– volume: 92
  start-page: 3103
  year: 2020
  ident: 10.1016/j.bbagen.2020.129674_bb0865
  article-title: In situ fluorescent and photoacoustic imaging of Golgi pH to elucidate the function of transmembrane protein 165
  publication-title: Anal. Chem.
  doi: 10.1021/acs.analchem.9b04709
– volume: 34
  start-page: 118
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0650
  article-title: Manganese transport via the transferrin mechanism
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2012.10.018
– volume: 1465
  start-page: 190
  year: 2000
  ident: 10.1016/j.bbagen.2020.129674_bb0670
  article-title: The ZIP family of metal transporters
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/S0005-2736(00)00138-3
– volume: 21
  start-page: 271
  year: 1999
  ident: 10.1016/j.bbagen.2020.129674_bb0485
  article-title: Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
  publication-title: Nat. Genet.
  doi: 10.1038/6784
– volume: 9
  start-page: 3087
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0965
  article-title: SLC10A7 mutations cause a skeletal dysplasia with amelogenesis imperfecta mediated by GAG biosynthesis defects
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-018-05191-8
– volume: 39
  start-page: 249
  year: 1973
  ident: 10.1016/j.bbagen.2020.129674_bb0215
  article-title: The hexokinases: kinetic, physical, and regulatory properties
  publication-title: Adv. Enzymol. Relat. Areas Mol. Biol.
– volume: 11
  start-page: 153
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0075
  article-title: Nutritional control via Tor signaling in Saccharomyces cerevisiae
  publication-title: Curr. Opin. Microbiol.
  doi: 10.1016/j.mib.2008.02.013
– volume: 1861
  start-page: 737
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0810
  article-title: Evidence for splice transcript variants of TMEM165, a gene involved in CDG
  publication-title: Biochim. Biophys. Acta BBA - Gen. Subj.
  doi: 10.1016/j.bbagen.2017.01.011
– volume: 102
  start-page: 1884
  year: 2003
  ident: 10.1016/j.bbagen.2020.129674_bb0595
  article-title: Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane
  publication-title: Blood
  doi: 10.1182/blood-2003-02-0425
– volume: 33
  start-page: 2669
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0935
  article-title: Involvement of thapsigargin and cyclopiazonic acid-sensitive pumps in the rescue of TMEM165-associated glycosylation defects by Mn2
  publication-title: FASEB J.
  doi: 10.1096/fj.201800387R
– volume: 20
  start-page: 445
  year: 1999
  ident: 10.1016/j.bbagen.2020.129674_bb0710
  article-title: Manganese and calcium transport in mitochondria: implications for manganese toxicity
  publication-title: Neurotoxicology
– volume: 275
  start-page: 40498
  year: 2000
  ident: 10.1016/j.bbagen.2020.129674_bb0175
  article-title: Expression cloning of human globoside synthase cDNAs identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M006902200
– volume: 444
  start-page: 1
  year: 1976
  ident: 10.1016/j.bbagen.2020.129674_bb0280
  article-title: Manganese metabolism in cows and goats
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/0304-4165(76)90218-X
– volume: 329
  start-page: 139
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0105
  article-title: The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes
  publication-title: Exp. Cell Res.
  doi: 10.1016/j.yexcr.2014.07.007
– volume: 466
  start-page: 11
  year: 2000
  ident: 10.1016/j.bbagen.2020.129674_bb0320
  article-title: The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cells
  publication-title: FEBS Lett.
  doi: 10.1016/S0014-5793(99)01780-9
– volume: 1862
  start-page: 394
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0930
  article-title: Investigating the function of Gdt1p in yeast Golgi glycosylation
  publication-title: Biochim. Biophys. Acta BBA - Gen. Subj.
  doi: 10.1016/j.bbagen.2017.11.006
– volume: 60
  start-page: 439
  year: 2011
  ident: 10.1016/j.bbagen.2020.129674_bb0300
  article-title: Calsequestrin distribution, structure and function, its role in normal and pathological situations and the effect of thyroid hormones
  publication-title: Physiol. Res.
  doi: 10.33549/physiolres.931989
– volume: 311
  start-page: 53
  year: 2001
  ident: 10.1016/j.bbagen.2020.129674_bb0415
  article-title: Manganese mimics the action of 1-methyl-4-phenylpyridinium ion, a dopaminergic neurotoxin, in rat striatal tissue slices
  publication-title: Neurosci. Lett.
  doi: 10.1016/S0304-3940(01)02144-9
– volume: 3
  year: 2011
  ident: 10.1016/j.bbagen.2020.129674_bb0745
  article-title: The Ca2+ pumps of the endoplasmic reticulum and golgi apparatus
  publication-title: Cold Spring Harb. Perspect. Biol.
  doi: 10.1101/cshperspect.a004184
– volume: 295
  start-page: 3865
  year: 2020
  ident: 10.1016/j.bbagen.2020.129674_bb0885
  article-title: The human Golgi protein TMEM165 transports calcium and manganese in yeast and bacterial cells
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.RA119.012249
– volume: 288
  start-page: 31963
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0170
  article-title: Crystal structures of β-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M113.509984
– volume: 60
  start-page: 949
  year: 1994
  ident: 10.1016/j.bbagen.2020.129674_bb0625
  article-title: Sex affects manganese absorption and retention by humans from a diet adequate in manganese
  publication-title: Am. J. Clin. Nutr.
  doi: 10.1093/ajcn/60.6.949
– volume: 278
  start-page: 39711
  year: 2003
  ident: 10.1016/j.bbagen.2020.129674_bb0165
  article-title: Chondroitin sulfate synthase-3 molecular cloning and characterization
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M304421200
– volume: 1131
  start-page: 183
  year: 2020
  ident: 10.1016/j.bbagen.2020.129674_bb0020
  article-title: An update to calcium binding proteins
  publication-title: Adv. Exp. Med. Biol.
  doi: 10.1007/978-3-030-12457-1_8
– volume: 15
  start-page: 303
  year: 1992
  ident: 10.1016/j.bbagen.2020.129674_bb0335
  article-title: Calcium-binding proteins in the nervous system
  publication-title: Trends Neurosci.
  doi: 10.1016/0166-2236(92)90081-I
– volume: 460
  start-page: 823
  year: 2009
  ident: 10.1016/j.bbagen.2020.129674_bb0005
  article-title: Metalloproteins and metal sensing
  publication-title: Nature
  doi: 10.1038/nature08300
– volume: 73
  start-page: 169
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0040
  article-title: The importance of magnesium in the human body: a systematic literature review
  publication-title: Adv. Clin. Chem.
  doi: 10.1016/bs.acc.2015.10.002
– volume: 6
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0950
  article-title: Retromer: a master conductor of endosome sorting
  publication-title: Cold Spring Harb. Perspect. Biol
  doi: 10.1101/cshperspect.a016774
– volume: 442
  start-page: 178
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0845
  article-title: Serum N-glycan and O-glycan analysis by mass spectrometry for diagnosis of congenital disorders of glycosylation
  publication-title: Anal. Biochem.
  doi: 10.1016/j.ab.2013.07.037
– volume: 294
  start-page: 9147
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0685
  article-title: The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.RA119.008762
– volume: 3
  start-page: 267
  year: 2011
  ident: 10.1016/j.bbagen.2020.129674_bb0395
  article-title: Role of metal Dyshomeostasis in Alzheimer disease
  publication-title: Met. Integr. Biometal Sci.
  doi: 10.1039/c0mt00074d
– volume: 34
  start-page: 441
  year: 1993
  ident: 10.1016/j.bbagen.2020.129674_bb0080
  article-title: Manganese and epilepsy: brain glutamine synthetase and liver arginase activities in genetically epilepsy prone and chronically seizured rats
  publication-title: Epilepsia
  doi: 10.1111/j.1528-1157.1993.tb02584.x
– volume: 35
  start-page: 71
  year: 2015
  ident: 10.1016/j.bbagen.2020.129674_bb0070
  article-title: Manganese is essential for neuronal health
  publication-title: Annu. Rev. Nutr.
  doi: 10.1146/annurev-nutr-071714-034419
– volume: 18
  start-page: 144
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0235
  article-title: Zinc and its importance for human health: an integrative review
  publication-title: J. Res. Med. Sci. Off. J. Isfahan Univ. Med. Sci.
– volume: 8
  start-page: 3163
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0700
  article-title: Functional analysis of SLC39A8 mutations and their implications for manganese deficiency and mitochondrial disorders
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-018-21464-0
– volume: 13
  start-page: 484
  year: 2004
  ident: 10.1016/j.bbagen.2020.129674_bb0090
  article-title: In vitro induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 expression in keratinocytes by boron and manganese
  publication-title: Exp. Dermatol.
  doi: 10.1111/j.0906-6705.2004.00197.x
– volume: 71
  start-page: 3281
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0510
  article-title: Current understanding of ZIP and ZnT zinc transporters in human health and diseases
  publication-title: Cell. Mol. Life Sci. CMLS
  doi: 10.1007/s00018-014-1617-0
– volume: 7
  start-page: 11601
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0680
  article-title: Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia
  publication-title: Nat. Commun.
  doi: 10.1038/ncomms11601
– volume: 113
  start-page: 313
  year: 2010
  ident: 10.1016/j.bbagen.2020.129674_bb0585
  article-title: TRP channels of intracellular membranes
  publication-title: J. Neurochem.
  doi: 10.1111/j.1471-4159.2010.06626.x
– volume: 445
  start-page: 417
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0895
  article-title: The Ca(2+)/H(+) antiporter TMEM165 expression, localization in the developing, lactating and involuting mammary gland parallels the secretory pathway Ca(2+) ATPase (SPCA1)
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2014.02.020
– volume: 6
  start-page: 477
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0520
  article-title: Congenital disorders of glycosylation
  publication-title: Ann. Transl. Med.
  doi: 10.21037/atm.2018.10.45
– volume: 100
  start-page: 216
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0830
  article-title: Mutations in ATP6V1E1 or ATP6V1A cause autosomal-recessive cutis Laxa
  publication-title: Am. J. Hum. Genet.
  doi: 10.1016/j.ajhg.2016.12.010
– volume: 28
  start-page: 892
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0800
  article-title: The evolutionarily conserved protein PHOTOSYNTHESIS AFFECTED MUTANT71 is required for efficient manganese uptake at the thylakoid membrane in Arabidopsis
  publication-title: Plant Cell
– volume: 18
  start-page: 2242
  year: 2009
  ident: 10.1016/j.bbagen.2020.129674_bb0260
  article-title: Human lysosomal alpha-mannosidases exhibit different inhibition and metal binding properties
  publication-title: Protein Sci. Publ. Protein Soc.
  doi: 10.1002/pro.235
– volume: 291
  start-page: 14773
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0430
  article-title: Direct comparison of manganese detoxification/efflux proteins and molecular characterization of ZnT10 protein as a manganese transporter
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M116.728014
– volume: 62
  start-page: 227
  year: 1989
  ident: 10.1016/j.bbagen.2020.129674_bb0220
  article-title: The phosphoglycerate mutases
  publication-title: Adv. Enzymol. Relat. Areas Mol. Biol.
– volume: 7
  year: 2012
  ident: 10.1016/j.bbagen.2020.129674_bb0100
  article-title: The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0042988
– volume: 17
  start-page: 529
  year: 2003
  ident: 10.1016/j.bbagen.2020.129674_bb0475
  article-title: Disorders of calcium homeostasis
  publication-title: Best Pract. Res. Clin. Endocrinol. Metab.
  doi: 10.1016/j.beem.2003.08.001
– volume: 75
  start-page: 59
  year: 1987
  ident: 10.1016/j.bbagen.2020.129674_bb0385
  article-title: Metal toxicity in the central nervous system
  publication-title: Environ. Health Perspect.
  doi: 10.1289/ehp.877559
– volume: 177
  start-page: 637
  year: 2007
  ident: 10.1016/j.bbagen.2020.129674_bb0230
  article-title: Zinc is a novel intracellular second messenger
  publication-title: J. Cell Biol.
  doi: 10.1083/jcb.200702081
– volume: 1993
  start-page: 277
  issue: 5
  year: 1997
  ident: 10.1016/j.bbagen.2020.129674_bb0035
  article-title: Structure of a human lysosomal sulfatase
  publication-title: Struct. Lond. Engl.
– volume: 294
  start-page: 3181
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0890
  article-title: Milk biosynthesis requires the Golgi cation exchanger TMEM165
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.RA118.006270
– volume: 29
  start-page: 466
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0340
  article-title: Manganese accumulates primarily in nuclei of cultured brain cells
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2008.02.012
– volume: 10
  start-page: 1514
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0960
  article-title: A Golgi-targeting fluorescent probe for labile Fe(ii) to reveal an abnormal cellular iron distribution induced by dysfunction of VPS35
  publication-title: Chem. Sci.
  doi: 10.1039/C8SC04386H
– volume: 62
  start-page: 436
  year: 2010
  ident: 10.1016/j.bbagen.2020.129674_bb0325
  article-title: Calnuc: emerging roles in calcium signaling and human diseases
  publication-title: IUBMB Life
  doi: 10.1002/iub.341
– volume: 101
  start-page: 251
  year: 1987
  ident: 10.1016/j.bbagen.2020.129674_bb0145
  article-title: Identification and characterization of UDP-GalNAc: NeuAc alpha 2-3Gal beta 1-4Glc(NAc) beta 1-4(GalNAc to Gal)N-acetylgalactosaminyltransferase in human blood plasma
  publication-title: J. Biochem. (Tokyo)
  doi: 10.1093/oxfordjournals.jbchem.a121898
– volume: 24
  start-page: 159
  year: 2011
  ident: 10.1016/j.bbagen.2020.129674_bb0500
  article-title: Vesicular distribution of secretory pathway Ca2+-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells
  publication-title: Biometals Int. J. Role Met. Ions Biol. Biochem. Med.
  doi: 10.1007/s10534-010-9384-3
– volume: 400
  start-page: 33
  year: 2006
  ident: 10.1016/j.bbagen.2020.129674_bb0255
  article-title: Man2C1, an alpha-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol
  publication-title: Biochem. J.
  doi: 10.1042/BJ20060945
– volume: 11
  start-page: 955
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0775
  article-title: The plastid envelope CHLOROPLAST MANGANESE TRANSPORTER1 is essential for manganese homeostasis in Arabidopsis
  publication-title: Mol. Plant
  doi: 10.1016/j.molp.2018.04.008
– volume: 40
  start-page: 8765
  year: 2001
  ident: 10.1016/j.bbagen.2020.129674_bb0190
  article-title: Independent Lec1A CHO glycosylation mutants arise from point mutations in N-acetylglucosaminyltransferase I that reduce affinity for both substrates molecular consequences based on the crystal structure of GlcNAc-TI
  publication-title: Biochemistry
  doi: 10.1021/bi015538b
– volume: 39
  start-page: 2149
  year: 2000
  ident: 10.1016/j.bbagen.2020.129674_bb0195
  article-title: Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity
  publication-title: Biochemistry
  doi: 10.1021/bi9916473
– volume: 293
  start-page: 5715
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0785
  article-title: Structure-function analysis of manganese exporter proteins across bacteria
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M117.790717
– volume: 35
  start-page: 195
  year: 2007
  ident: 10.1016/j.bbagen.2020.129674_bb0465
  article-title: Searching for a role of NCX/NCKX exchangers in neurodegeneration
  publication-title: Mol. Neurobiol.
  doi: 10.1007/s12035-007-0007-0
– volume: 58
  start-page: 730
  year: 1992
  ident: 10.1016/j.bbagen.2020.129674_bb0350
  article-title: Manganese uptake and efflux in cultured rat astrocytes
  publication-title: J. Neurochem.
  doi: 10.1111/j.1471-4159.1992.tb09778.x
– volume: 19
  start-page: 1534
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0425
  article-title: Genetic disorders of manganese metabolism
  publication-title: Curr. Neurol. Neurosci.
  doi: 10.1007/s11910-019-0942-y
– volume: 289
  start-page: 28138
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0130
  article-title: Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M114.597831
– volume: 11
  start-page: 1315
  year: 2010
  ident: 10.1016/j.bbagen.2020.129674_bb0735
  article-title: The SPCA1 Ca2+ pump and intracellular membrane trafficking
  publication-title: Traffic
  doi: 10.1111/j.1600-0854.2010.01096.x
– volume: 590
  start-page: 2086
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0725
  article-title: Mn(2+) transport by Ca(2+) -ATPase of sarcoplasmic reticulum
  publication-title: FEBS Lett.
  doi: 10.1002/1873-3468.12244
– volume: 19
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0900
  article-title: Acidic and uncharged polar residues in the consensus motifs of the yeast Ca2+transporter Gdt1p are required for calcium transport
  publication-title: Cell. Microbiol
  doi: 10.1111/cmi.12729
– volume: 87
  start-page: S169
  issue: Suppl. 2
  year: 2002
  ident: 10.1016/j.bbagen.2020.129674_bb0015
  article-title: Calcium intake, calcium bioavailability and bone health
  publication-title: Br. J. Nutr.
  doi: 10.1079/BJN/2002534
– volume: 14
  start-page: 1129
  year: 1989
  ident: 10.1016/j.bbagen.2020.129674_bb0345
  article-title: Manganese(II) dynamics and distribution in glial cells cultured from chick cerebral cortex
  publication-title: Neurochem. Res.
  doi: 10.1007/BF00965619
– volume: 46
  start-page: 111
  year: 1981
  ident: 10.1016/j.bbagen.2020.129674_bb0270
  article-title: Zinc transport proteins in plasma
  publication-title: Br. J. Nutr.
  doi: 10.1079/BJN19810014
– volume: 26
  start-page: 21
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0815
  article-title: TMEM165 deficiency: postnatal changes in glycosylation
  publication-title: JIMD Rep.
  doi: 10.1007/8904_2015_455
– volume: 19
  start-page: 13
  year: 2004
  ident: 10.1016/j.bbagen.2020.129674_bb0480
  article-title: Genetics of hereditary disorders of magnesium homeostasis
  publication-title: Pediatr. Nephrol. Berl. Ger.
  doi: 10.1007/s00467-003-1293-z
– volume: 8
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0720
  article-title: The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0085519
– volume: 21
  start-page: 1282
  year: 2010
  ident: 10.1016/j.bbagen.2020.129674_bb0440
  article-title: Manganese-induced trafficking and turnover of the cis-Golgi glycoprotein GPP130
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.e09-11-0985
– volume: 81
  start-page: 87
  year: 2002
  ident: 10.1016/j.bbagen.2020.129674_bb0330
  article-title: The calcium-binding protein p54/NEFA is a novel luminal resident of medial Golgi cisternae that traffics independently of mannosidase II
  publication-title: Eur. J. Cell Biol.
  doi: 10.1078/0171-9335-00224
– volume: 23
  start-page: 1655
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0620
  article-title: Manganese metabolism in humans
  publication-title: Front. Biosci. Landmark Ed.
  doi: 10.2741/4665
– volume: 1993
  start-page: 853
  issue: 3
  year: 1995
  ident: 10.1016/j.bbagen.2020.129674_bb0030
  article-title: Structures and mechanisms of glycosyl hydrolases
  publication-title: Struct. Lond. Engl.
– volume: 14
  start-page: 3482
  year: 2003
  ident: 10.1016/j.bbagen.2020.129674_bb0185
  article-title: Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.e03-03-0130
– volume: 110
  start-page: 6859
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0765
  article-title: Newly characterized Golgi-localized family of proteins is involved in calcium and pH homeostasis in yeast and human cells
  publication-title: Proc. Natl. Acad. Sci.
  doi: 10.1073/pnas.1219871110
– volume: 3
  start-page: 17025
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0600
  article-title: Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice
  publication-title: Cell Discov.
  doi: 10.1038/celldisc.2017.25
– volume: 130
  start-page: 4604
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0065
  article-title: Manganous phosphate acts as a superoxide dismutase
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja710162n
– volume: 39
  start-page: 45
  year: 2006
  ident: 10.1016/j.bbagen.2020.129674_bb0285
  article-title: Homeostatic and toxic mechanisms regulating manganese uptake, retention, and elimination
  publication-title: Biol. Res.
  doi: 10.4067/S0716-97602006000100006
– volume: 287
  start-page: 13510
  year: 2012
  ident: 10.1016/j.bbagen.2020.129674_bb0370
  article-title: Metal transport across biomembranes: emerging models for a distinct chemistry
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.R111.319343
– volume: 119
  start-page: 1461
  year: 1989
  ident: 10.1016/j.bbagen.2020.129674_bb0655
  article-title: Identification of transferrin as the major plasma carrier protein for manganese introduced orally or intravenously or after in vitro addition in the rat
  publication-title: J. Nutr.
  doi: 10.1093/jn/119.10.1461
– volume: 8
  start-page: 145
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0840
  article-title: Bone dysplasia as a key feature in three patients with a novel congenital disorder of glycosylation (CDG) type II due to a deep Intronic splice mutation in TMEM165
  publication-title: JIMD Rep.
  doi: 10.1007/8904_2012_172
– volume: 37
  start-page: 587
  year: 2000
  ident: 10.1016/j.bbagen.2020.129674_bb0060
  article-title: Manganese superoxide dismutase
  publication-title: Met. Ions Biol. Syst.
– volume: 117
  start-page: 169
  year: 2010
  ident: 10.1016/j.bbagen.2020.129674_bb0390
  article-title: Altered manganese homeostasis and manganese toxicity in a Huntington’s disease striatal cell model are not explained by defects in the iron transport system
  publication-title: Toxicol. Sci. Off. J. Soc. Toxicol.
  doi: 10.1093/toxsci/kfq174
– volume: 285
  start-page: 32141
  year: 2010
  ident: 10.1016/j.bbagen.2020.129674_bb0690
  article-title: ZRT/IRT-like protein 14 (ZIP14) promotes the cellular assimilation of iron from transferrin
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M110.143248
– volume: 31
  start-page: 1111
  year: 1999
  ident: 10.1016/j.bbagen.2020.129674_bb0645
  article-title: The transferrin receptor: role in health and disease
  publication-title: Int. J. Biochem. Cell Biol.
  doi: 10.1016/S1357-2725(99)00070-9
– volume: 6
  start-page: 24282
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0850
  article-title: Yeast Gdt1 is a Golgi-localized calcium transporter required for stress-induced calcium signaling and protein glycosylation
  publication-title: Sci. Rep.
  doi: 10.1038/srep24282
– volume: 34
  start-page: 14079
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0435
  article-title: SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.2329-14.2014
– volume: 169
  start-page: 374
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0590
  article-title: Mn2+ dynamics in manganese-enhanced MRI (MEMRI): Cav12 channel-mediated uptake and preferential accumulation in projection terminals
  publication-title: NeuroImage
  doi: 10.1016/j.neuroimage.2017.12.054
– volume: 322
  start-page: 1204
  year: 2004
  ident: 10.1016/j.bbagen.2020.129674_bb0495
  article-title: SPCA1 pumps and Hailey-Hailey disease
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1016/j.bbrc.2004.07.128
– volume: 206
  start-page: 635
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0755
  article-title: Cofilin recruits F-actin to SPCA1 and promotes Ca2+−mediated secretory cargo sorting
  publication-title: J. Cell Biol.
  doi: 10.1083/jcb.201311052
– volume: 65
  start-page: 2039
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0225
  article-title: Evolution of the arginase fold and functional diversity
  publication-title: Cell. Mol. Life Sci. CMLS
  doi: 10.1007/s00018-008-7554-z
– volume: 9
  start-page: 1028
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0630
  article-title: Influence of iron metabolism on manganese transport and toxicity
  publication-title: Met. Integr. Biometal Sci.
  doi: 10.1039/C7MT00079K
– volume: 22
  start-page: 2914
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0805
  article-title: Impact of disease-causing mutations on TMEM165 subcellular localization, a recently identified protein involved in CDG-II
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/ddt146
– volume: 474
  start-page: 1481
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0880
  article-title: Manganese-induced turnover of TMEM165
  publication-title: Biochem. J.
  doi: 10.1042/BCJ20160910
– volume: 476
  start-page: 3281
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0925
  article-title: Investigating the functional link between TMEM165 and SPCA1
  publication-title: Biochem. J.
  doi: 10.1042/BCJ20190488
– ident: 10.1016/j.bbagen.2020.129674_bb0375
– volume: 10
  start-page: 15
  year: 1999
  ident: 10.1016/j.bbagen.2020.129674_bb0615
  article-title: Manganese deficiency and toxicity: are high or low dietary amounts of manganese cause for concern?
  publication-title: BioFactors Oxf. Engl.
  doi: 10.1002/biof.5520100102
– volume: 17
  start-page: 35
  year: 2004
  ident: 10.1016/j.bbagen.2020.129674_bb0140
  article-title: Effect of the manganese ion on human alpha3/4 fucosyltransferase III activity
  publication-title: Biometals Int. J. Role Met. Ions Biol. Biochem. Med.
  doi: 10.1023/A:1024485718843
– volume: 40
  start-page: 32
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0550
  article-title: Impaired glycosylation and cutis laxa caused by mutations in the vesicular H+-ATPase subunit ATP6V0A2
  publication-title: Nat. Genet.
  doi: 10.1038/ng.2007.45
– volume: 578
  start-page: 419
  year: 2020
  ident: 10.1016/j.bbagen.2020.129674_bb0450
  article-title: ATP13A2 deficiency disrupts lysosomal polyamine export
  publication-title: Nature
  doi: 10.1038/s41586-020-1968-7
– volume: 112
  start-page: 1190
  year: 2010
  ident: 10.1016/j.bbagen.2020.129674_bb0705
  article-title: Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation
  publication-title: J. Neurochem.
  doi: 10.1111/j.1471-4159.2009.06534.x
– volume: 69
  start-page: 249
  year: 2012
  ident: 10.1016/j.bbagen.2020.129674_bb0610
  article-title: Nramp: from sequence to structure and mechanism of divalent metal import
  publication-title: Curr. Top. Membr.
  doi: 10.1016/B978-0-12-394390-3.00010-0
– volume: 165
  start-page: 123
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0905
  article-title: Dissection of TMEM165 function in Golgi glycosylation and its Mn2+ sensitivity
  publication-title: Biochimie
  doi: 10.1016/j.biochi.2019.07.016
– volume: 26
  start-page: 1252
  year: 2011
  ident: 10.1016/j.bbagen.2020.129674_bb0095
  article-title: Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone
  publication-title: J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res.
  doi: 10.1002/jbmr.326
– volume: 11
  start-page: 711
  year: 2001
  ident: 10.1016/j.bbagen.2020.129674_bb0180
  article-title: Production of soluble human alpha3-fucosyltransferase (FucT VII) by membrane targeting and in vivo proteolysis
  publication-title: Glycobiology
  doi: 10.1093/glycob/11.9.711
– volume: 45
  start-page: 295
  year: 2020
  ident: 10.1016/j.bbagen.2020.129674_bb0545
  article-title: Structure and roles of V-type ATPases
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/j.tibs.2019.12.007
– volume: 257
  start-page: 9261
  year: 1982
  ident: 10.1016/j.bbagen.2020.129674_bb0365
  article-title: Determination of free and bound manganese(II) in hepatocytes from fed and faster rats
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(18)34061-4
– volume: 282
  start-page: 9564
  year: 2007
  ident: 10.1016/j.bbagen.2020.129674_bb0150
  article-title: Structural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motif
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M610998200
– volume: 272
  start-page: 30873
  year: 1997
  ident: 10.1016/j.bbagen.2020.129674_bb0310
  article-title: BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.272.49.30873
– volume: 4
  start-page: 551
  year: 1994
  ident: 10.1016/j.bbagen.2020.129674_bb0245
  article-title: Mammalian alpha-mannosidases--multiple forms but a common purpose?
  publication-title: Glycobiology
  doi: 10.1093/glycob/4.5.551
– volume: 1
  start-page: 194
  year: 2010
  ident: 10.1016/j.bbagen.2020.129674_bb0355
  article-title: Manganese accumulates within golgi apparatus in dopaminergic cells as revealed by synchrotron X-rayFluorescence nanoimaging
  publication-title: Cjem. Neurosci.
– volume: 116
  start-page: 9865
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0565
  article-title: Mutations in MAGT1 lead to a glycosylation disorder with a variable phenotype
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1817815116
– volume: 75
  start-page: 475
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0250
  article-title: Structural and functional insights into phosphomannose isomerase: the role of zinc and catalytic residues
  publication-title: Acta Crystallogr. Sect. Struct. Biol.
  doi: 10.1107/S2059798319004169
– volume: 7
  start-page: 389
  year: 2007
  ident: 10.1016/j.bbagen.2020.129674_bb0535
  article-title: Congenital disorders of glycosylation: CDG-I, CDG-II, and beyond
  publication-title: Curr. Mol. Med.
  doi: 10.2174/156652407780831548
– volume: 151
  start-page: 69
  year: 1977
  ident: 10.1016/j.bbagen.2020.129674_bb0420
  article-title: Manganese mutagenesis in yeast VI Mn2+ uptake, mitDNA replication and ER induction: comparison with other divalent cations
  publication-title: Mol. Gen. Genet. MGG
  doi: 10.1007/BF00446914
– volume: 110
  start-page: 277
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0055
  article-title: Manganese and the brain
  publication-title: Int. Rev. Neurobiol.
  doi: 10.1016/B978-0-12-410502-7.00013-2
– volume: 109
  start-page: 4722
  year: 2009
  ident: 10.1016/j.bbagen.2020.129674_bb0740
  article-title: Manganese homeostasis in Saccharomyces cerevisiae
  publication-title: Chem. Rev.
  doi: 10.1021/cr900031u
– volume: 119
  start-page: 615
  year: 2006
  ident: 10.1016/j.bbagen.2020.129674_bb0305
  article-title: Beyond lectins: the calnexin/calreticulin chaperone system of the endoplasmic reticulum
  publication-title: J. Cell Sci.
  doi: 10.1242/jcs.02856
– volume: 663
  start-page: 66
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0455
  article-title: The PMR1 pump in alpha-synuclein toxicity and neurodegeneration
  publication-title: Neurosci. Lett.
  doi: 10.1016/j.neulet.2017.08.006
– volume: 127
  start-page: 2407
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0695
  article-title: Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI90896
– volume: 4
  start-page: 435
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0290
  article-title: Metallothioneins, unconventional proteins from unconventional animals: a long journey from nematodes to mammals
  publication-title: Biomolecules
  doi: 10.3390/biom4020435
– volume: 9
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0770
  article-title: Molecular evolution of a novel family of putative calcium transporters
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0100851
– volume: 41
  start-page: 57
  year: 2016
  ident: 10.1016/j.bbagen.2020.129674_bb0580
  article-title: N-linked glycosylation and homeostasis of the endoplasmic reticulum
  publication-title: Curr. Opin. Cell Biol.
  doi: 10.1016/j.ceb.2016.03.021
– volume: 77
  start-page: 521
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0110
  article-title: Glycosyltransferases: structures, functions, and mechanisms
  publication-title: Annu. Rev. Biochem.
  doi: 10.1146/annurev.biochem.76.061005.092322
– volume: 293
  start-page: 8048
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0860
  article-title: The yeast protein Gdt1p transports Mn2+ ions and thereby regulates manganese homeostasis in the Golgi
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.RA118.002324
– volume: 50
  start-page: 184
  year: 2011
  ident: 10.1016/j.bbagen.2020.129674_bb0295
  article-title: Ca(2+) signalling in the Golgi apparatus
  publication-title: Cell Calcium
  doi: 10.1016/j.ceca.2011.01.006
– volume: 294
  start-page: 7878
  year: 2019
  ident: 10.1016/j.bbagen.2020.129674_bb0910
  article-title: An N-terminal Ca2+−binding motif regulates the secretory pathway Ca2+/Mn2+−transport ATPase SPCA1
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.RA118.006250
– volume: 9
  start-page: 1131
  year: 2000
  ident: 10.1016/j.bbagen.2020.129674_bb0490
  article-title: Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/9.7.1131
– volume: 4
  year: 2009
  ident: 10.1016/j.bbagen.2020.129674_bb0515
  article-title: Evolutionary descent of prion genes from the ZIP family of metal ion transporters
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0007208
– volume: 7
  start-page: 3913
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0870
  article-title: H + and Pi Byproducts of Glycosylation Affect Ca 2+ Homeostasis and Are Retrieved from the Golgi Complex by Homologs of TMEM165 and XPR1, G3amp58
  publication-title: GenesGenomesGenetics
– volume: 266
  start-page: 7155
  year: 1991
  ident: 10.1016/j.bbagen.2020.129674_bb0315
  article-title: Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum
  publication-title: J. Biol. Chem.
  doi: 10.1016/S0021-9258(20)89624-0
– volume: 13
  start-page: 81
  year: 2013
  ident: 10.1016/j.bbagen.2020.129674_bb0265
  article-title: Calcium in health and disease
  publication-title: Met. Ions Life Sci.
  doi: 10.1007/978-94-007-7500-8_4
– ident: 10.1016/j.bbagen.2020.129674_bb0380
– volume: 126
  start-page: 981
  year: 2006
  ident: 10.1016/j.bbagen.2020.129674_bb0470
  article-title: Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer’s disease-linked mutations
  publication-title: Cell
  doi: 10.1016/j.cell.2006.06.059
– volume: 61
  start-page: 643
  year: 2018
  ident: 10.1016/j.bbagen.2020.129674_bb0525
  article-title: Congenital disorders of glycosylation (CDG): Quo vadis?
  publication-title: Eur. J. Med. Genet.
  doi: 10.1016/j.ejmg.2017.10.012
– volume: 8
  start-page: 261
  year: 2007
  ident: 10.1016/j.bbagen.2020.129674_bb0530
  article-title: Congenital disorders of glycosylation: a rapidly expanding disease family
  publication-title: Annu. Rev. Genomics Hum. Genet.
  doi: 10.1146/annurev.genom.8.080706.092327
– volume: 1979
  start-page: 252
  issue: 51
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0085
  article-title: Role of bradykinin, nitric oxide, and angiotensin II type 2 receptor in imidapril-induced angiogenesis, Hypertens
  publication-title: Dallas Tex
– volume: 14
  start-page: 593
  year: 2004
  ident: 10.1016/j.bbagen.2020.129674_bb0115
  article-title: Structure and catalytic cycle of beta-1,4-galactosyltransferase
  publication-title: Curr. Opin. Struct. Biol.
  doi: 10.1016/j.sbi.2004.09.006
– volume: 102
  start-page: 1375
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0855
  article-title: Galactose supplementation in patients with TMEM165-CDG rescues the glycosylation defects
  publication-title: J. Clin. Endocrinol. Metab.
  doi: 10.1210/jc.2016-3443
– volume: 274
  start-page: 4481
  year: 1999
  ident: 10.1016/j.bbagen.2020.129674_bb0915
  article-title: Regulation of transition metal transport across the yeast plasma membrane
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.274.8.4481
– volume: 386
  start-page: 227
  year: 2005
  ident: 10.1016/j.bbagen.2020.129674_bb0155
  article-title: Human xylosyltransferase I: functional and biochemical characterization of cysteine residues required for enzymic activity
  publication-title: Biochem. J.
  doi: 10.1042/BJ20041206
– volume: 120
  start-page: 1002
  year: 1996
  ident: 10.1016/j.bbagen.2020.129674_bb0135
  article-title: Detection of UDP-D-xylose: alpha-D-xyloside alpha 1-->3xylosyltransferase activity in human hepatoma cell line HepG2
  publication-title: J. Biochem. (Tokyo)
  doi: 10.1093/oxfordjournals.jbchem.a021492
– volume: 18
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0675
  article-title: Recent advances in the role of SLC39A/ZIP zinc transporters In vivo
  publication-title: Int. J. Mol. Sci
  doi: 10.3390/ijms18122708
– volume: 49
  start-page: 150
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0715
  article-title: TMEM165 deficiencies in congenital disorders of glycosylation type II (CDG-II): clues and evidences for roles of the protein in Golgi functions and ion homeostasis
  publication-title: Tissue Cell
  doi: 10.1016/j.tice.2016.06.006
– volume: 28
  start-page: 2569
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0875
  article-title: Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.e17-05-0326
– volume: 112
  start-page: 4268
  year: 2008
  ident: 10.1016/j.bbagen.2020.129674_bb0945
  article-title: Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2
  publication-title: Blood
  doi: 10.1182/blood-2008-04-150953
– volume: 97
  start-page: 894
  year: 2015
  ident: 10.1016/j.bbagen.2020.129674_bb0560
  article-title: SLC39A8 deficiency: a disorder of manganese transport and glycosylation
  publication-title: Am. J. Hum. Genet.
  doi: 10.1016/j.ajhg.2015.11.003
– year: 2007
  ident: 10.1016/j.bbagen.2020.129674_bb0010
– volume: 9
  year: 2020
  ident: 10.1016/j.bbagen.2020.129674_bb0780
  article-title: Homologous Proteins of the Manganese Transporter PAM71 Are Localized in the Golgi Apparatus and Endoplasmic Reticulum
  publication-title: Plants Basel Switz
– volume: 1742
  start-page: 103
  year: 2004
  ident: 10.1016/j.bbagen.2020.129674_bb0025
  article-title: The Ca2+/Mn2+ pumps in the Golgi apparatus
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbamcr.2004.08.018
– volume: 2014
  year: 2014
  ident: 10.1016/j.bbagen.2020.129674_bb0445
  article-title: Mutations in the ATP13A2 gene and Parkinsonism: a preliminary review
  publication-title: Biomed. Res. Int.
  doi: 10.1155/2014/371256
– volume: 280
  start-page: 11608
  year: 2005
  ident: 10.1016/j.bbagen.2020.129674_bb0750
  article-title: A novel isoform of the secretory pathway Ca2+,Mn(2+)-ATPase, hSPCA2, has unusual properties and is expressed in the brain
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M413116200
– volume: 387
  start-page: 43
  year: 2017
  ident: 10.1016/j.bbagen.2020.129674_bb0240
  article-title: Cobalt toxicity in humans-a review of the potential sources and systemic health effects
  publication-title: Toxicology
  doi: 10.1016/j.tox.2017.05.015
SSID ssj0000595
Score 2.4700208
SecondaryResourceType review_article
Snippet About half of the eukaryotic proteins bind biometals that participate in their structure and functions in virtually all physiological processes, including...
SourceID hal
proquest
pubmed
crossref
elsevier
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 129674
SubjectTerms Animals
Antiporters - metabolism
Biochemistry, Molecular Biology
Biological Transport
Biometal homeostasis
calcium
Cation Transport Proteins - metabolism
cobalt
congenital abnormalities
Congenital disorders of glycosylation
Congenital Disorders of Glycosylation - metabolism
Congenital Disorders of Glycosylation - pathology
cytosol
extracellular space
Glycosylation
Golgi Apparatus - metabolism
Golgi Apparatus - pathology
Homeostasis
Humans
Life Sciences
magnesium
Manganese
Manganese - metabolism
metalloproteins
sugars
TMEM165
zinc
Title Biometals and glycosylation in humans: Congenital disorders of glycosylation shed lights into the crucial role of Golgi manganese homeostasis
URI https://dx.doi.org/10.1016/j.bbagen.2020.129674
https://www.ncbi.nlm.nih.gov/pubmed/32599014
https://www.proquest.com/docview/2419093703
https://www.proquest.com/docview/2477624007
https://hal.science/hal-02997375
Volume 1864
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB6VIkQvFZRHl0dlENewIbbjmtuyoiyvXqBSb5btOLupVknVbJH20n_Af2YmThaBVCpxiRTLEyczE8838jwAXqHRziQXKnF0EdbJRBepT4L0TqOB4LmgbOSvx_nsRHw6ladbMB1yYSisst_7457e7db9yLjn5vi8qsbf6FAP4YTMCNUf5uS3C6FIy19f_Q7zQPgg40mCSGj2kD7XxXg5hz8tVUHNqMyCzpW4zjzdWlCc5HUgtDNGR_dgt0eRbBJf9D5shXoP7sS-kus9uDsd2rg9gJ_vKMEeIXbLbF2w-XLtm3YdI-BYVbOuSV_7lk0byrKiFiKs6Ctytqwp_yJoF6FgS3LoWyReNQzxI_OoH6jGjCIVieRDs5xXDB87t9Tfki3wBRpEoW3VPoSTo_ffp7Ok78GQeKHkKuEu2ICYzLkshBK3h9J6jj4K1dRBeIBcTZ0ShZYF-m65Qw566bmzWSqtCoXnj2C7buqwD8wjGvA2O7TCliIXpS219lpo5z36NbYYAR9Yb3xfoJz6ZCzNEIl2ZqLADAnMRIGNINlQnccCHTfMV4NUzR-KZtCG3ED5EpVgswjV5Z5NvhgaS9GoK67kjzcjeDHoiEFB0-kLsrq5bA1CJZ0iGEz5v-YoNE7Uqn4Ej6OCbdbj6KjSmfeT__6Ap7BDdzEU8Rlsry4uw3OEVCt30P0zB3B78vHz7PgX_RwgZA
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB6VItReEJTX8jSIa9gQ23HDrawoC2x7oZV6s2zH2Q1aJVW9RdoL_4D_zEycLAKpVOKSQ-JJnJmx5xt5HgCv0WhnkguVWLoIY2VSlKlLvHS2QAPBc0HZyEfH-fRUfD6TZ1swGXJhKKyy3_vjnt7t1v2dcc_N8Xldj7_SoR7CCZkRqt_P0W-_KXD5UhuDNz9-x3kgfpDxKEEkNHzIn-uCvKzFVUtlUDOqs1DkSlxln24sKFDyKhTaWaPDO3C7h5HsIM70Lmz5Zg9uxcaS6z3YmQx93O7Bz_eUYY8YOzDTlGy-XLs2rGMIHKsb1nXpC-_YpKU0K-ohwsq-JGdgbfUXQVj4ki3Jow9IvGoZAkjmUEFQjxmFKhLJx3Y5rxm-dm6owSVb4ARahKGhDvfh9PDDyWSa9E0YEieUXCXceuMRlFmbeV_h_lAZx9FJoaI6iA-Qq6lVoixkic5bbpGDTjpuTZZKo3zp-APYbtrGPwLmEA44k-0bYSqRi8pUReEKUVjn0LEx5Qj4wHrt-grl1ChjqYdQtG86CkyTwHQU2AiSDdV5rNBxzXg1SFX_oWkajcg1lK9QCTYfocLc04OZpnspWnXFlfz-dgQvBx3RKGg6fkFWt5dBI1YqUkSDKf_XGIXWiXrVj-BhVLDN9zh6qnTo_fi_f-AF7ExPjmZ69un4yxPYpScxLvEpbK8uLv0zxFcr-7xbP78AW-Ih8g
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Biometals+and+glycosylation+in+humans%3A+Congenital+disorders+of+glycosylation+shed+lights+into+the+crucial+role+of+Golgi+manganese+homeostasis&rft.jtitle=Biochimica+et+biophysica+acta.+General+subjects&rft.au=Foulquier%2C+Fran%C3%A7ois&rft.au=Legrand%2C+Dominique&rft.date=2020-10-01&rft.issn=1872-8006&rft.eissn=1872-8006&rft.volume=1864&rft.issue=10&rft.spage=129674&rft_id=info:doi/10.1016%2Fj.bbagen.2020.129674&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0304-4165&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0304-4165&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0304-4165&client=summon