The Mechanism Underlying the Regulation of Long Non-coding RNA MEG3 in Cerebral Ischemic Stroke

• Published in: Cellular and molecular neurobiology Vol. 43; no. 1; pp. 69 - 78
• Main Authors: Zhao, Yanfang, Liu, Yingying, Zhang, Qili, Liu, Hongliang, Xu, Jianing
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.01.2023; Springer Nature B.V
• Subjects: Angiogenesis; Biomarkers; Biomedical and Life Sciences; Biomedicine; Blood-brain barrier; Brain Ischemia - metabolism; Cell Biology; Cell death; Drug delivery; Humans; Hypoxia; Ischemia; Ischemic Stroke - genetics; Morbidity; Neurobiology; Neurosciences; Non-coding RNA; Nucleotides; Review Paper; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; Stroke; Stroke - metabolism; Therapeutic targets; MEG3; LncRNA; Angiogenesis; Neuronal cell death; Cerebral ischemic stroke

Cerebral ischemic stroke is one of the leading causes of morbidity and mortality worldwide, and rapidly increasing annually with no more effective therapeutic measures. Thus, the novel diagnostic and prognostic biomarkers are urgent to be identified for prevention and therapy of ischemic stroke. Rec...