Contextual Fear Conditioning in Zebrafish

• Published in: Learning & memory (Cold Spring Harbor, N.Y.) Vol. 24; no. 10; pp. 516 - 523
• Main Authors: Kenney, Justin W, Scott, Ian C, Josselyn, Sheena A, Frankland, Paul W
• Format: Journal Article
• Language: English
• Published: United States Cold Spring Harbor Laboratory Press 01.10.2017
• Subjects: Adults; Animals; Association Learning - drug effects; Association Learning - physiology; Conditioning; Conditioning (Psychology) - drug effects; Conditioning (Psychology) - physiology; Context Effect; Discrimination (Psychology) - drug effects; Discrimination (Psychology) - physiology; Dizocilpine Maleate - pharmacology; Electroshock; Excitatory Amino Acid Antagonists - pharmacology; Experiments; Extinction, Psychological - drug effects; Extinction, Psychological - physiology; Fear; Fear - drug effects; Fear - physiology; Female; Genetics; Learning Processes; Male; Memory; Models, Animal; Motor Activity - drug effects; Motor Activity - physiology; Negative Reinforcement; Psychotropic Drugs - pharmacology; Spatial Behavior - drug effects; Spatial Behavior - physiology; Species Specificity; Stimuli; Time Factors; Zebrafish - physiology

Zebrafish are a genetically tractable vertebrate that hold considerable promise for elucidating the molecular basis of behavior. Although numerous recent advances have been made in the ability to precisely manipulate the zebrafish genome, much less is known about many aspects of learning and memory...