Pupil diameter encodes the idiosyncratic, cognitive complexity of belief updating

• Published in: eLife Vol. 9
• Main Authors: Filipowicz, Alexandre LS, Glaze, Christopher M, Kable, Joseph W, Gold, Joshua I
• Format: Journal Article
• Language: English
• Published: England eLife Sciences Publications Ltd 18.05.2020; eLife Sciences Publications, Ltd
• Subjects: Arousal; Arousal - physiology; Auditory Perception - physiology; Behavior; belief updating; Clinical decision making; Cognition - physiology; Cognitive ability; complexity; Decision making; Forecasting; Humans; Information processing; Mental task performance; Neuroscience; Pupil - physiology; pupillometry; Reflex, Pupillary - physiology; surprise; uncertainty; complexity; surprise; decision-making; belief updating; neuroscience; pupillometry; uncertainty; human
• ISSN: 2050-084X; 2050-084X
• DOI: 10.7554/eLife.57872

Pupils tend to dilate in response to surprising events, but it is not known whether these responses are primarily stimulus driven or instead reflect a more nuanced relationship between pupil-linked arousal systems and cognitive expectations. Using an auditory adaptive decision-making task, we show that evoked pupil diameter is more parsimoniously described as signaling violations of learned, top-down expectations than changes in low-level stimulus properties. We further show that both baseline and evoked pupil diameter is modulated by the degree to which individual subjects use these violations to update their subsequent expectations, as reflected in the complexity of their updating strategy. Together these results demonstrate a central role for idiosyncratic cognitive processing in how arousal systems respond to new inputs and, via our complexity-based analyses, offer a potential framework for understanding these effects in terms of both inference processes aimed to reduce belief uncertainty and more traditional notions of mental effort.