PrEP-001 prophylactic effect against rhinovirus and influenza virus - RESULTS of 2 randomized trials - Malcolm, Bruce Albert; Aerts, Caroline Anne; Dubois, Kristof Johan; Geurts, Frederik Joris; Marien, Kris; Rusch, Sarah; Van Dijck, Alex Henri; Verloes, Rene; Vingerhoets, Johan (Antiviral research, 2018)
Keywords: Administration, Intranasal; Drug-Related Side Effects and Adverse Reactions - epidemiology; Drug-Related Side Effects and Adverse Reactions - pathology; Healthy Volunteers; Humans; Immunologic Factors - administration & dosage; Immunologic Factors - adverse effects; Influenza A Virus, H3N2 Subtype - immunology; Influenza, Human - pathology; Influenza, Human - prevention & control; Innate immune response; Nasal; Nasal Mucosa - immunology; Picornaviridae Infections - pathology; Picornaviridae Infections - prevention & control; Placebos - administration & dosage; Poly I-C - administration & dosage; Poly I-C - adverse effects; Poly I:C; Powders - administration & dosage; Powders - adverse effects; Prophylaxis; Randomized Controlled Trials as Topic; Rhinovirus - immunology; Treatment Outcome; Upper respiratory viral infections; Viral disease; Upper respiratory viral infections; Nasal; Poly I:C; Innate immune response; Viral disease; Prophylaxis