CT textural analysis of hepatic metastatic colorectal cancer: pre-treatment tumor heterogeneity correlates with pathology and clinical outcomes

• Published in: Abdominal imaging Vol. 40; no. 7; pp. 2331 - 2337
• Main Authors: Lubner, Meghan G., Stabo, Nicholas, Lubner, Sam J., del Rio, Alejandro Munoz, Song, Chihwa, Halberg, Richard B., Pickhardt, Perry J.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.10.2015; Springer Nature B.V
• Subjects: Adult; Aged; Aged, 80 and over; Clinical outcomes; Colorectal Neoplasms - pathology; Contrast Media; Female; Gastroenterology; Hepatology; Humans; Imaging; Liver - diagnostic imaging; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - secondary; Male; Medicine; Medicine & Public Health; Middle Aged; Radiographic Image Enhancement; Radiology; Reproducibility of Results; Tomography, X-Ray Computed; CT; Heterogeneity; Texture; Colorectal cancer; Metastases

Purpose The purpose of the study was to determine if CT texture features of untreated hepatic metastatic colorectal cancer (CRC) relate to pathologic features and clinical outcomes. Methods Tumor texture analysis was performed on single hepatic metastatic lesions on pre-treatment contrast-enhanced C...