Toward clinically usable CAD for lung cancer screening with computed tomography

• Published in: European radiology Vol. 24; no. 11; pp. 2719 - 2728
• Main Authors: Brown, Matthew S., Lo, Pechin, Goldin, Jonathan G., Barnoy, Eran, Kim, Grace Hyun J., McNitt-Gray, Michael F., Aberle, Denise R.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2014; Springer Nature B.V
• Subjects: Diagnosis, Differential; Diagnostic Radiology; Early Detection of Cancer; Female; Humans; Imaging; Internal Medicine; Interventional Radiology; Lung - diagnostic imaging; Lung cancer; Lung Neoplasms - diagnostic imaging; Male; Medicine; Medicine & Public Health; Neuroradiology; Oncology; Radiology; Reproducibility of Results; ROC Curve; Tomography, X-Ray Computed - methods; Ultrasound; X-ray computerized axial tomography; Early detection of cancer; Computer-assisted diagnosis; Lung cancer; Multiple pulmonary nodules

Objectives The purpose of this study was to define clinically appropriate, computer-aided lung nodule detection (CAD) requirements and protocols based on recent screening trials. In the following paper, we describe a CAD evaluation methodology based on a publically available, annotated computed tomo...