Nail Toxicity after Treatment with Docetaxel: A Prospective Analysis in Patients with Advanced Non-small Cell Lung Cancer

• Published in: Japanese journal of clinical oncology Vol. 37; no. 6; pp. 424 - 428
• Main Authors: Hong, Junshik, Park, Se Hoon, Choi, Soo Jin, Lee, Seok Ho, Lee, Kyu Chan, Lee, Jae-Ik, Kyung, Sun Young, An, Chang Hyeok, Lee, Sang Pyo, Park, Jeong Woong, Jeong, Sung Hwan, Nam, Eunmi, Bang, Soo-Mee, Cho, Eun Kyung, Shin, Dong Bok, Lee, Jae Hoon
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.06.2007; Oxford Publishing Limited (England)
• Subjects: Aged; Antineoplastic Agents - administration & dosage; Antineoplastic Agents - toxicity; Antineoplastic Combined Chemotherapy Protocols - toxicity; Carcinoma, Non-Small-Cell Lung - drug therapy; chemotherapy; docetaxel; Drug Administration Schedule; Humans; Lung cancer; nail changes; Prospective Studies; Taxoids - administration & dosage; Taxoids - toxicity; docetaxel; nail changes; chemotherapy

Objective Nail toxicity is one of the most frequent non-hematologic toxicities of docetaxel and often deteriorates patients' quality of life, leading to treatment discontinuation. To define the incidence of nail change as well as its association with specific risk factors, we prospectively inve...