Calcineurin Inhibition in Deceased Organ Donors: A Systematic Review and Meta-analysis of Preclinical Studies

• Published in: Transplantation direct Vol. 9; no. 9; p. e1519
• Main Authors: D'Aragon, Frédérick, Rousseau, William, Breau, Ruth, Aminaei, Daniel, Ichai, Carole, Boyd, Gordon J., Burns, Karen E. A., Cardinal, Héloïse, Carrier, François-Martin, Chassé, Michaël, Chaudhury, Prosanto, Dhanani, Sonny, English, Shane W., Frenette, Anne Julie, Hanna, Steven, Knoll, Gregory, Lauzier, François, Oczkowski, Simon, Rochwerg, Bram, Shamseddin, Khaled, Slessarev, Marat, Treleaven, Darin, Turgeon, Alexis F., Weiss, Matthew J., Selzner, Markus, Meade, Maureen O.
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.09.2023; Wolters Kluwer
• Subjects: Organ Donation and Procurement

Background. Preconditioning deceased organ donors with calcineurin inhibitors (CNIs) may reduce ischemia-reperfusion injury to improve transplant outcomes. Methods. We searched MEDLINE, EMBASE, Cochrane Library, and conference proceedings for animal models of organ donation and transplantation, comp...