Multiple imputation by chained equations: what is it and how does it work?

• Published in: International journal of methods in psychiatric research Vol. 20; no. 1; pp. 40 - 49
• Main Authors: Azur, Melissa J., Stuart, Elizabeth A., Frangakis, Constantine, Leaf, Philip J.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.03.2011
• Subjects: analyze; Computer programs; Data processing; Epidemiologic Methods; Humans; Mathematical models; missing data; Models, Statistical; multiple imputation; Research Design; Reviews; software; multiple imputation; missing data; analyze

Multivariate imputation by chained equations (MICE) has emerged as a principled method of dealing with missing data. Despite properties that make MICE particularly useful for large imputation procedures and advances in software development that now make it accessible to many researchers, many psychi...