African and Asian Mitochondrial DNA Haplogroups Confer Resistance Against Diabetic Stresses on Retinal Pigment Epithelial Cybrid Cells In Vitro - Dolinko, Andrew H.; Chwa, Marilyn; Atilano, Shari R.; Kenney, M. Cristina (Molecular neurobiology, 2020)
Keywords: Adult; Aged; Apoptosis; Asian Americans; Asian People; Azacytidine; Biomedical and Life Sciences; Biomedicine; Blindness; Cell Biology; Cell lines; Cells, Cultured; Cybrids; Demethylation; Deoxyribonucleic acid; Diabetes; Diabetes mellitus; Diabetes Mellitus - metabolism; Diabetic retinopathy; Diabetic Retinopathy - genetics; DNA; DNA methylation; DNA, Mitochondrial - genetics; Edema; Epithelium; Female; Humans; Hyperglycemia; Hypoxia; Ischemia; Macular Edema - genetics; Male; Metabolism; Middle Aged; Mitochondria - metabolism; Mitochondrial DNA; Neurobiology; Neurology; Neurosciences; Polymorphism, Single Nucleotide - genetics; Population studies; Retina; Retinal pigment epithelium; Retinal Pigment Epithelium - cytology; Retinopathy; Signal Transduction - genetics; Single-nucleotide polymorphism; Vascularization; White People; Retinal pigment epithelial cells; African and Asian mitochondrial DNA haplogroups; Diabetic retinopathy (DR); Cybrid cell model; Hyperglycemic and hypoxic stresses