Adenovirus virus-associated RNA and translation control

• Published in: Journal of virology Vol. 65; no. 11; pp. 5657 - 5662
• Main Authors: Mathews, M B, Shenk, T
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.11.1991
• Subjects: Adenoviridae - genetics; adenovirus; Adenoviruses, Human - genetics; Animals; Base Sequence; Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Viral; Genetics; Genome, Viral; Humans; Microbiology; Molecular Sequence Data; Nucleic Acid Conformation; Protein Biosynthesis; RNA, Viral - genetics; Transcription, Genetic; Virology; Virus; Regulation(control); Genetical translation; Adenoviridae; Review; RNA

The adenovirus genome is transcribed by two RNA polymerases furnished by the host cell. RNA polymerase II transcribes both strands of the viral DNA over nearly all of its length, and the resultant mRNAs encode more than 50 viral proteins. RNA polymerase III transcribes less than 1% of the viral geno...