The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis
Inflammatory stimuli cause a state of emergency myelopoiesis leading to neutrophil-like monocyte expansion. However, their function, the committed precursors, or growth factors remain elusive. In this study we find that Ym1+Ly6Chi monocytes, an immunoregulatory entity of neutrophil-like monocytes, a...
Saved in:
Published in | Cell reports (Cambridge) Vol. 42; no. 3; p. 112165 |
---|---|
Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
28.03.2023
Elsevier |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Inflammatory stimuli cause a state of emergency myelopoiesis leading to neutrophil-like monocyte expansion. However, their function, the committed precursors, or growth factors remain elusive. In this study we find that Ym1+Ly6Chi monocytes, an immunoregulatory entity of neutrophil-like monocytes, arise from progenitors of neutrophil 1 (proNeu1). Granulocyte-colony stimulating factor (G-CSF) favors the production of neutrophil-like monocytes through previously unknown CD81+CX3CR1lo monocyte precursors. GFI1 promotes the differentiation of proNeu2 from proNeu1 at the cost of producing neutrophil-like monocytes. The human counterpart of neutrophil-like monocytes that also expands in response to G-CSF is found in CD14+CD16− monocyte fraction. The human neutrophil-like monocytes are discriminated from CD14+CD16− classical monocytes by CXCR1 expression and the capacity to suppress T cell proliferation. Collectively, our findings suggest that the aberrant expansion of neutrophil-like monocytes under inflammatory conditions is a process conserved between mouse and human, which may be beneficial for the resolution of inflammation.
[Display omitted]
•Mouse neutrophil-like monocytes arise from proNeu1 during emergency myelopoiesis•G-CSF favors a differentiation of proNeu1 into CD81+CX3CR1lo monocyte precursors•Human CXCR1+CD14+CD16− monocytes also expand in response to G-CSF treatment•Human neutrophil-like monocytes suppress the proliferation of T cells
Ikeda et al. find that immunoregulatory monocytes expand in response to G-CSF during emergency myelopoiesis. Unlike classical monocytes that differentiate from monocyte-dendritic cell progenitors through the common monocyte progenitors, immunoregulatory monocytes differentiate from early neutrophil progenitors. These findings may be applied to the development of immunoregulatory monocyte-targeted therapy for human inflammatory diseases. |
---|---|
AbstractList | Inflammatory stimuli cause a state of emergency myelopoiesis leading to neutrophil-like monocyte expansion. However, their function, the committed precursors, or growth factors remain elusive. In this study we find that Ym1+Ly6Chi monocytes, an immunoregulatory entity of neutrophil-like monocytes, arise from progenitors of neutrophil 1 (proNeu1). Granulocyte-colony stimulating factor (G-CSF) favors the production of neutrophil-like monocytes through previously unknown CD81+CX3CR1lo monocyte precursors. GFI1 promotes the differentiation of proNeu2 from proNeu1 at the cost of producing neutrophil-like monocytes. The human counterpart of neutrophil-like monocytes that also expands in response to G-CSF is found in CD14+CD16− monocyte fraction. The human neutrophil-like monocytes are discriminated from CD14+CD16− classical monocytes by CXCR1 expression and the capacity to suppress T cell proliferation. Collectively, our findings suggest that the aberrant expansion of neutrophil-like monocytes under inflammatory conditions is a process conserved between mouse and human, which may be beneficial for the resolution of inflammation. Inflammatory stimuli cause a state of emergency myelopoiesis leading to neutrophil-like monocyte expansion. However, their function, the committed precursors, or growth factors remain elusive. In this study we find that Ym1 Ly6C monocytes, an immunoregulatory entity of neutrophil-like monocytes, arise from progenitors of neutrophil 1 (proNeu1). Granulocyte-colony stimulating factor (G-CSF) favors the production of neutrophil-like monocytes through previously unknown CD81 CX3CR1 monocyte precursors. GFI1 promotes the differentiation of proNeu2 from proNeu1 at the cost of producing neutrophil-like monocytes. The human counterpart of neutrophil-like monocytes that also expands in response to G-CSF is found in CD14 CD16 monocyte fraction. The human neutrophil-like monocytes are discriminated from CD14 CD16 classical monocytes by CXCR1 expression and the capacity to suppress T cell proliferation. Collectively, our findings suggest that the aberrant expansion of neutrophil-like monocytes under inflammatory conditions is a process conserved between mouse and human, which may be beneficial for the resolution of inflammation. Inflammatory stimuli cause a state of emergency myelopoiesis leading to neutrophil-like monocyte expansion. However, their function, the committed precursors, or growth factors remain elusive. In this study we find that Ym1+Ly6Chi monocytes, an immunoregulatory entity of neutrophil-like monocytes, arise from progenitors of neutrophil 1 (proNeu1). Granulocyte-colony stimulating factor (G-CSF) favors the production of neutrophil-like monocytes through previously unknown CD81+CX3CR1lo monocyte precursors. GFI1 promotes the differentiation of proNeu2 from proNeu1 at the cost of producing neutrophil-like monocytes. The human counterpart of neutrophil-like monocytes that also expands in response to G-CSF is found in CD14+CD16− monocyte fraction. The human neutrophil-like monocytes are discriminated from CD14+CD16− classical monocytes by CXCR1 expression and the capacity to suppress T cell proliferation. Collectively, our findings suggest that the aberrant expansion of neutrophil-like monocytes under inflammatory conditions is a process conserved between mouse and human, which may be beneficial for the resolution of inflammation. [Display omitted] •Mouse neutrophil-like monocytes arise from proNeu1 during emergency myelopoiesis•G-CSF favors a differentiation of proNeu1 into CD81+CX3CR1lo monocyte precursors•Human CXCR1+CD14+CD16− monocytes also expand in response to G-CSF treatment•Human neutrophil-like monocytes suppress the proliferation of T cells Ikeda et al. find that immunoregulatory monocytes expand in response to G-CSF during emergency myelopoiesis. Unlike classical monocytes that differentiate from monocyte-dendritic cell progenitors through the common monocyte progenitors, immunoregulatory monocytes differentiate from early neutrophil progenitors. These findings may be applied to the development of immunoregulatory monocyte-targeted therapy for human inflammatory diseases. |
ArticleNumber | 112165 |
Author | Yamashita, Masakatsu Yotsumoto, Satoshi Suzuki, Risa Asano, Kenichi Hirai, Hideyo Kishida, Keigo Hayashi, Yoshihiro Asahina, Yasuhiro Kamatani, Takashi Kitamura, Daiki Murakawa, Miyako Tsunoda, Tatsuhiko Yoshimura, Ayana Nishiyama, Akira Morita, Mitsuki Osada, Yuya Shichino, Shigeyuki Kuwahara, Makoto Kurotaki, Daisuke Harada, Hironori Ikeda, Naoki Yokota, Asumi Nishimura, Koutarou Kubota, Hiroaki Iwata, Ayaka Tanaka, Masato Seki, Takao Harada, Yuka Tamura, Tomohiko |
Author_xml | – sequence: 1 givenname: Naoki surname: Ikeda fullname: Ikeda, Naoki organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 2 givenname: Hiroaki surname: Kubota fullname: Kubota, Hiroaki organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 3 givenname: Risa surname: Suzuki fullname: Suzuki, Risa organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 4 givenname: Mitsuki surname: Morita fullname: Morita, Mitsuki organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 5 givenname: Ayana surname: Yoshimura fullname: Yoshimura, Ayana organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 6 givenname: Yuya surname: Osada fullname: Osada, Yuya organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 7 givenname: Keigo surname: Kishida fullname: Kishida, Keigo organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 8 givenname: Daiki surname: Kitamura fullname: Kitamura, Daiki organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 9 givenname: Ayaka surname: Iwata fullname: Iwata, Ayaka organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 10 givenname: Satoshi surname: Yotsumoto fullname: Yotsumoto, Satoshi organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 11 givenname: Daisuke surname: Kurotaki fullname: Kurotaki, Daisuke organization: Department of Immunology, Yokohama City University Graduate School of Medicine, Kanagawa 236-0004, Japan – sequence: 12 givenname: Koutarou surname: Nishimura fullname: Nishimura, Koutarou organization: Department of Immunology, Yokohama City University Graduate School of Medicine, Kanagawa 236-0004, Japan – sequence: 13 givenname: Akira surname: Nishiyama fullname: Nishiyama, Akira organization: Department of Immunology, Yokohama City University Graduate School of Medicine, Kanagawa 236-0004, Japan – sequence: 14 givenname: Tomohiko surname: Tamura fullname: Tamura, Tomohiko organization: Department of Immunology, Yokohama City University Graduate School of Medicine, Kanagawa 236-0004, Japan – sequence: 15 givenname: Takashi surname: Kamatani fullname: Kamatani, Takashi organization: Laboratory for Medical Science Mathematics, Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0032, Japan – sequence: 16 givenname: Tatsuhiko surname: Tsunoda fullname: Tsunoda, Tatsuhiko organization: Laboratory for Medical Science Mathematics, Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0032, Japan – sequence: 17 givenname: Miyako surname: Murakawa fullname: Murakawa, Miyako organization: Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan – sequence: 18 givenname: Yasuhiro surname: Asahina fullname: Asahina, Yasuhiro organization: Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan – sequence: 19 givenname: Yoshihiro surname: Hayashi fullname: Hayashi, Yoshihiro organization: Laoratory of Oncology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 20 givenname: Hironori surname: Harada fullname: Harada, Hironori organization: Laoratory of Oncology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 21 givenname: Yuka surname: Harada fullname: Harada, Yuka organization: Department of Clinical Laboratory, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo 113-8677, Japan – sequence: 22 givenname: Asumi surname: Yokota fullname: Yokota, Asumi organization: Laboratory of Stem Cells Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 23 givenname: Hideyo surname: Hirai fullname: Hirai, Hideyo organization: Laboratory of Stem Cells Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 24 givenname: Takao surname: Seki fullname: Seki, Takao organization: Department of Biochemistry, Toho University School of Medicine, Tokyo 143-8540, Japan – sequence: 25 givenname: Makoto surname: Kuwahara fullname: Kuwahara, Makoto organization: Department of Immunology, Graduate School of Medicine, Ehime University, Ehime 791-0295, Japan – sequence: 26 givenname: Masakatsu surname: Yamashita fullname: Yamashita, Masakatsu organization: Department of Immunology, Graduate School of Medicine, Ehime University, Ehime 791-0295, Japan – sequence: 27 givenname: Shigeyuki surname: Shichino fullname: Shichino, Shigeyuki organization: Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba 278-0022, Japan – sequence: 28 givenname: Masato surname: Tanaka fullname: Tanaka, Masato email: mtanaka@toyaku.ac.jp organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan – sequence: 29 givenname: Kenichi orcidid: 0000-0002-0218-1517 surname: Asano fullname: Asano, Kenichi email: asanok@toyaku.ac.jp organization: Laboratory of Immune Regulation, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/36862552$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kc1u3CAUhVGVKkmTvEEVedmNp1yMMbOpVEX9iRSpm9kjDNcTRjY4gCt52TcvqdOoq7IBwbnniPO9I2c-eCTkPdAdUBAfTzuDY8R5xyhrdgAMRPuGXDIGUAPj3dk_5wtyk9KJliUowJ6fk4tGSMHall2SX4dHrFDHca08LjmG-dGNtQnT5HJGW80xHNG7HGKqdI8xap-L1rphwIg-O52xcj6Hyk3T4kPE4zLqIl-rKfhg1oypskt0_ljhhLGYmfK04hjm4DC5dE3eDnpMePOyX5HD1y-Hu-_1w49v93efH2rDO57rYW9bNIxZqS1tOW8HQXsqpGw6Cl3f9Y1FaTuORgI0YKSWHXIum75n0rTNFbnfbG3QJzVHN-m4qqCd-nMR4lHpmJ0ZUTUc0DZcMxw0N10rQWoQVvBhPwAHVrw-bF6lnacFU1aTSwXIqD2GJSnWSRAMpBRFyjepiSGliMNrNFD1jFKd1IZSPaNUG8oydvuSsPQT2tehv-CK4NMmwFLZT4dRJeNKt2hdRJPLp9z_E34DQdi2ZA |
CitedBy_id | crossref_primary_10_3389_fimmu_2024_1398153 crossref_primary_10_1182_blood_2023021298 crossref_primary_10_1093_jleuko_qiad160 crossref_primary_10_1007_s00395_023_01001_5 crossref_primary_10_1016_j_redox_2023_102933 crossref_primary_10_1186_s12974_024_03032_8 crossref_primary_10_1182_blood_2023020257 crossref_primary_10_3389_fimmu_2023_1287656 crossref_primary_10_1016_j_immuni_2024_04_019 crossref_primary_10_1016_j_celrep_2024_113894 crossref_primary_10_4049_jimmunol_2400007 crossref_primary_10_1093_jleuko_qiae036 |
Cites_doi | 10.1038/cddis.2012.176 10.1016/j.immuni.2016.02.015 10.1016/j.immuni.2021.04.004 10.1038/s41590-022-01189-z 10.1093/nar/gkt214 10.4049/jimmunol.172.7.4410 10.1146/annurev-immunol-042718-041728 10.1046/j.1365-2257.1998.00083.x 10.1038/75556 10.1073/pnas.1621177114 10.1038/sj.bjc.6690344 10.3389/fimmu.2019.01642 10.1038/nri3073 10.1186/1471-2105-10-106 10.1016/S1074-7613(03)00174-2 10.1073/pnas.0608981103 10.1038/ncomms5978 10.1074/jbc.M115.658559 10.1016/j.immuni.2017.10.021 10.1038/nature20611 10.1038/nbt.4314 10.1038/sj.onc.1209144 10.1038/nature12026 10.1093/bioinformatics/btu674 10.1038/nmeth.1923 10.1038/nature19348 10.1038/s41586-019-0969-x 10.1038/s41419-021-04308-0 10.1038/ni.2638 10.1016/j.molcel.2010.05.004 10.1161/ATVBAHA.118.311022 10.1084/jem.20160800 10.1084/jem.20181952 10.1182/blood-2012-06-437863 10.1093/nar/gky1038 10.1016/j.cell.2021.04.048 10.1093/nar/gks540 10.3389/fimmu.2021.663115 10.1093/bioinformatics/bts635 10.1158/0008-5472.CAN-06-3037 10.4049/jimmunol.1001950 10.1016/j.immuni.2019.08.008 10.1126/sciadv.abj4641 10.1038/ng.3646 10.1126/science.aax0249 10.1126/science.1142883 10.1126/science.1117729 10.1111/j.1365-2257.2004.00628.x 10.3389/fimmu.2015.00423 10.1126/sciimmunol.aat0207 10.1016/j.cellimm.2014.03.019 10.1126/science.aah4573 10.1002/cyto.a.20258 10.1016/j.cell.2019.08.009 10.1093/nar/gkq405 10.1038/s41590-021-00871-y 10.1016/S1074-7613(02)00501-0 10.1093/bioinformatics/btaa042 10.1038/s41592-021-01346-6 10.1038/s42003-022-03536-0 10.1038/ni1354 10.1016/j.immuni.2020.06.005 10.1126/sciadv.abg0505 10.1016/j.immuni.2018.10.005 10.1007/s00262-019-02302-2 10.1023/A:1010920819831 10.1186/s12864-018-4772-0 10.1073/pnas.75.10.5142 10.1016/j.immuni.2016.12.001 10.1182/blood-2009-07-235028 10.1186/s13059-014-0550-8 10.1038/nbt.4096 10.1038/nmeth.4150 10.1093/nar/gks042 10.4049/jimmunol.1901530 |
ContentType | Journal Article |
Copyright | 2023 The Author(s) Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved. |
Copyright_xml | – notice: 2023 The Author(s) – notice: Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved. |
DBID | 6I. AAFTH CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 DOA |
DOI | 10.1016/j.celrep.2023.112165 |
DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic DOAJ Directory of Open Access Journals |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE |
Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Biology |
EISSN | 2211-1247 |
EndPage | 112165 |
ExternalDocumentID | oai_doaj_org_article_341ed34a2efa4c75818a16d64f9f1412 10_1016_j_celrep_2023_112165 36862552 S2211124723001766 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GroupedDBID | 0R~ 0SF 4.4 457 53G 5VS 6I. AACTN AAEDT AAEDW AAFTH AAIKJ AAKRW AALRI AAUCE AAXUO ABMAC ABMWF ACGFO ACGFS ADBBV ADEZE AENEX AEXQZ AFTJW AGHFR AITUG ALKID ALMA_UNASSIGNED_HOLDINGS AMRAJ BAWUL BCNDV DIK EBS EJD FCP FDB FRP GROUPED_DOAJ GX1 IXB KQ8 M41 M48 NCXOZ O-L O9- OK1 RCE ROL SSZ AAMRU ADVLN AKRWK CGR CUY CVF ECM EIF NPM AAYXX CITATION HZ~ IPNFZ RIG 7X8 |
ID | FETCH-LOGICAL-c474t-f9d5ec22d8ad05445f60b068837017b7b3de8d74ec81131c8a87e4483bb28c53 |
IEDL.DBID | M48 |
ISSN | 2211-1247 |
IngestDate | Tue Oct 22 15:15:29 EDT 2024 Thu Oct 24 23:21:23 EDT 2024 Thu Sep 26 15:25:25 EDT 2024 Sat Sep 28 08:20:39 EDT 2024 Sat Nov 04 15:31:33 EDT 2023 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 3 |
Keywords | demand-adapted myelopoiesis CP: Immunology emergency myelopoiesis CXCR1 monocyte neutrophil-like monocyte Ym1 machine learning G-CSF ontogeny |
Language | English |
License | This is an open access article under the CC BY-NC-ND license. Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c474t-f9d5ec22d8ad05445f60b068837017b7b3de8d74ec81131c8a87e4483bb28c53 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0002-0218-1517 |
OpenAccessLink | https://doaj.org/article/341ed34a2efa4c75818a16d64f9f1412 |
PMID | 36862552 |
PQID | 2781621886 |
PQPubID | 23479 |
PageCount | 1 |
ParticipantIDs | doaj_primary_oai_doaj_org_article_341ed34a2efa4c75818a16d64f9f1412 proquest_miscellaneous_2781621886 crossref_primary_10_1016_j_celrep_2023_112165 pubmed_primary_36862552 elsevier_sciencedirect_doi_10_1016_j_celrep_2023_112165 |
PublicationCentury | 2000 |
PublicationDate | 2023-03-28 |
PublicationDateYYYYMMDD | 2023-03-28 |
PublicationDate_xml | – month: 03 year: 2023 text: 2023-03-28 day: 28 |
PublicationDecade | 2020 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States |
PublicationTitle | Cell reports (Cambridge) |
PublicationTitleAlternate | Cell Rep |
PublicationYear | 2023 |
Publisher | Elsevier Inc Elsevier |
Publisher_xml | – name: Elsevier Inc – name: Elsevier |
References | Yáñez, Coetzee, Olsson, Muench, Berman, Hazelett, Salomonis, Grimes, Goodridge (bib10) 2017; 47 Hock, Hamblen, Rooke, Traver, Bronson, Cameron, Orkin (bib19) 2003; 18 Corces, Buenrostro, Wu, Greenside, Chan, Koenig, Snyder, Pritchard, Kundaje, Greenleaf (bib75) 2016; 48 Wolf, Yáñez, Barman, Goodridge (bib1) 2019; 10 Becht, McInnes, Healy, Dutertre, Kwok, Ng, Ginhoux, Newell (bib15) 2018; 37 Shichino, Ueha, Hashimoto, Ogawa, Aoki, Wu, Chen, Kitabatake, Ouji-Sageshima, Sawabata (bib62) 2022; 5 Lohse, Bolger, Nagel, Fernie, Lunn, Stitt, Usadel (bib58) 2012; 40 Hegde, Leader, Merad (bib46) 2021; 54 Kurotaki, Yamamoto, Nishiyama, Uno, Ban, Ichino, Sasaki, Matsunaga, Yoshinari, Ryo (bib18) 2014; 5 Ingersoll, Spanbroek, Lottaz, Gautier, Frankenberger, Hoffmann, Lang, Haniffa, Collin, Tacke (bib29) 2010; 115 Ranaghan, Drake, Humphreys, Morris (bib41) 1998; 20 Mi, Muruganujan, Ebert, Huang, Thomas (bib72) 2019; 47 Liu, Persad, Inghirami, Sen, Amorosi, Goldenberg, Ibrahim (bib40) 2004; 26 Ikeda, Asano, Kikuchi, Uchida, Ikegami, Takagi, Yotsumoto, Shibuya, Makino-Okamura, Fukuyama (bib13) 2018; 3 Chung, Storey (bib73) 2015; 31 Wynn, Vannella (bib36) 2016; 44 Fogg, Sibon, Miled, Jung, Aucouturier, Littman, Cumano, Geissmann (bib7) 2006; 311 Murray, Wynn (bib37) 2011; 11 Ziegler-Heitbrock (bib28) 2014; 289 Calzetti, Finotti, Tamassia, Bianchetto-Aguilera, Castellucci, Canè, Lonardi, Cavallini, Matte, Gasperini (bib33) 2022; 23 Cao, Spielmann, Qiu, Huang, Ibrahim, Hill, Zhang, Mundlos, Christiansen, Steemers (bib63) 2019; 566 Olsson, Venkatasubramanian, Chaudhri, Aronow, Salomonis, Singh, Grimes (bib31) 2016; 537 Teh, Chooi, Liu, Kwok, Lai, Ayub Ow Yong, Ng, Li, Tan, Evrard (bib42) 2022; 8 Dutertre, Becht, Irac, Khalilnezhad, Narang, Khalilnezhad, Ng, van den Hoogen, Leong, Lee (bib14) 2019; 51 Bassler, Schulte-Schrepping, Warnat-Herresthal, Aschenbrenner, Schultze (bib27) 2019; 37 Ziegler-Heitbrock (bib2) 2015; 6 Takahashi, Duprez, Grootjans, Cauwels, Nerinckx, DuHadaway, Goossens, Roelandt, Van Hauwermeiren, Libert (bib34) 2012; 3 Langmead, Salzberg (bib64) 2012; 9 Hamers, Dinh, Thomas, Marcovecchio, Blatchley, Nakao, Kim, McSkimming, Taylor, Nguyen (bib30) 2019; 39 Ashburner, Ball, Blake, Botstein, Butler, Cherry, Davis, Dolinski, Dwight, Eppig (bib68) 2000; 25 Gabrilovich, Bronte, Chen, Colombo, Ochoa, Ostrand-Rosenberg, Schreiber (bib45) 2007; 67 Mastio, Condamine, Dominguez, Kossenkov, Donthireddy, Veglia, Lin, Wang, Fu, Zhou (bib48) 2019; 216 Hao, Hao, Andersen-Nissen, Mauck, Zheng, Butler, Lee, Wilk, Darby, Zager (bib23) 2021; 184 Nakatsu, Iwashita, Sakoda, Ono, Nagata, Matsunaga, Fukushima, Fujishiro, Kushiyama, Kamata (bib50) 2015; 290 Hu, Zhang, Li, Zuo, Ma, Ma, Yin, Gao, Yang, Zhao (bib20) 2021; 12 Qiu, Hill, Packer, Lin, Ma, Trapnell (bib24) 2017; 14 McCarthy, Chen, Smyth (bib66) 2012; 40 Heinz, Benner, Spann, Bertolino, Lin, Laslo, Cheng, Murre, Singh, Glass (bib65) 2010; 38 Street, Risso, Fletcher, Das, Ngai, Yosef, Purdom, Dudoit (bib16) 2018; 19 Villani, Satija, Reynolds, Sarkizova, Shekhar, Fletcher, Griesbeck, Butler, Zheng, Lazo (bib32) 2017; 356 Hand, Till (bib70) 2001; 45 Dobin, Davis, Schlesinger, Drenkow, Zaleski, Jha, Batut, Chaisson, Gingeras (bib59) 2013; 29 Stassen, Siu, Lee, Ho, So, Tsia (bib57) 2020; 36 Zhu, Jankovic, Grinberg, Guo, Paul (bib53) 2006; 103 Kwok, Becht, Xia, Ng, Teh, Tan, Evrard, Li, Tran, Tan (bib12) 2020; 53 Hahne, LeMeur, Brinkman, Ellis, Haaland, Sarkar, Spidlen, Strain, Gentleman (bib55) 2009; 10 Reyes, García-Castro, Esquivel, Hornedo, Cortes-Funes, Solovera, Alvarez-Mon (bib39) 1999; 80 Parks, Roederer, Moore (bib69) 2006; 69 Sunderkötter, Nikolic, Dillon, Van Rooijen, Stehling, Drevets, Leenen (bib3) 2004; 172 Geissmann, Jung, Littman (bib5) 2003; 19 Hirai, Zhang, Dayaram, Hetherington, Mizuno, Imanishi, Akashi, Tenen (bib22) 2006; 7 Liu, Gu, Chakarov, Bleriot, Kwok, Chen, Shin, Huang, Dress, Dutertre (bib38) 2019; 178 Bennett, Rao, Mitchell (bib44) 1978; 75 Hettinger, Richards, Hansson, Barra, Joschko, Krijgsveld, Feuerer (bib9) 2013; 14 Emig, Salomonis, Baumbach, Lengauer, Conklin, Albrecht (bib67) 2010; 38 Auffray, Fogg, Garfa, Elain, Join-Lambert, Kayal, Sarnacki, Cumano, Lauvau, Geissmann (bib6) 2007; 317 Butler, Hoffman, Smibert, Papalexi, Satija (bib76) 2018; 36 Cassetta, Baekkevold, Brandau, Bujko, Cassatella, Dorhoi, Krieg, Lin, Loré, Marini (bib47) 2019; 68 Becht, Tolstrup, Dutertre, Morawski, Campbell, Ginhoux, Newell, Gottardo, Headley (bib54) 2021; 7 Zhang, Newton, Kummerfeld, Webster, Kirkpatrick, Phu, Eastham-Anderson, Liu, Lee, Wu (bib21) 2017; 114 Gulati, Sikandar, Wesche, Manjunath, Bharadwaj, Berger, Ilagan, Kuo, Hsieh, Cai (bib74) 2020; 367 Melsen, van Ostaijen-Ten Dam, Lankester, Schilham, van den Akker (bib71) 2020; 205 Love, Huber, Anders (bib61) 2014; 15 Satoh, Nakagawa, Sugihara, Kuwahara, Ashihara, Yamane, Minowa, Fukushima, Ebina, Yoshioka (bib11) 2017; 541 Lange, Bergen, Klein, Setty, Reuter, Bakhti, Lickert, Ansari, Schniering, Schiller (bib25) 2022; 19 Feng, Wang, Shin, Masiuk, Qi, Morse (bib51) 2011; 186 Sterneck, Zhu, Ramirez, Jorcano, Smart (bib52) 2006; 25 McInnes, Healy, Melville (bib56) 2018 Menezes, Melandri, Anselmi, Perchet, Loschko, Dubrot, Patel, Gautier, Hugues, Longhi (bib4) 2016; 45 Guilliams, Mildner, Yona (bib8) 2018; 49 Liao, Smyth, Shi (bib60) 2013; 41 Kurotaki, Osato, Nishiyama, Yamamoto, Ban, Sato, Nakabayashi, Umehara, Miyake, Matsumoto (bib17) 2013; 121 Chong, Evrard, Devi, Chen, Lim, See, Zhang, Adrover, Lee, Tan (bib43) 2016; 213 Mossadegh-Keller, Sarrazin, Kandalla, Espinosa, Stanley, Nutt, Moore, Sieweke (bib26) 2013; 497 Murakami, Sasaki, Nishiyama, Kurotaki, Kawase, Ban, Nakabayashi, Kanzaki, Sekita, Nakajima (bib49) 2021; 22 Shibuya, Kamiyama, Sawada, Kikuchi, Maruyama, Sawado, Ikeda, Asano, Kurotaki, Tamura (bib35) 2021; 12 Mossadegh-Keller (10.1016/j.celrep.2023.112165_bib26) 2013; 497 Olsson (10.1016/j.celrep.2023.112165_bib31) 2016; 537 Fogg (10.1016/j.celrep.2023.112165_bib7) 2006; 311 Murakami (10.1016/j.celrep.2023.112165_bib49) 2021; 22 Kurotaki (10.1016/j.celrep.2023.112165_bib17) 2013; 121 Liu (10.1016/j.celrep.2023.112165_bib40) 2004; 26 Gulati (10.1016/j.celrep.2023.112165_bib74) 2020; 367 Hao (10.1016/j.celrep.2023.112165_bib23) 2021; 184 Lange (10.1016/j.celrep.2023.112165_bib25) 2022; 19 McCarthy (10.1016/j.celrep.2023.112165_bib66) 2012; 40 Ziegler-Heitbrock (10.1016/j.celrep.2023.112165_bib2) 2015; 6 Hettinger (10.1016/j.celrep.2023.112165_bib9) 2013; 14 Qiu (10.1016/j.celrep.2023.112165_bib24) 2017; 14 McInnes (10.1016/j.celrep.2023.112165_bib56) 2018 Villani (10.1016/j.celrep.2023.112165_bib32) 2017; 356 Langmead (10.1016/j.celrep.2023.112165_bib64) 2012; 9 Chung (10.1016/j.celrep.2023.112165_bib73) 2015; 31 Kurotaki (10.1016/j.celrep.2023.112165_bib18) 2014; 5 Mastio (10.1016/j.celrep.2023.112165_bib48) 2019; 216 Dutertre (10.1016/j.celrep.2023.112165_bib14) 2019; 51 Satoh (10.1016/j.celrep.2023.112165_bib11) 2017; 541 Cassetta (10.1016/j.celrep.2023.112165_bib47) 2019; 68 Wynn (10.1016/j.celrep.2023.112165_bib36) 2016; 44 Shichino (10.1016/j.celrep.2023.112165_bib62) 2022; 5 Wolf (10.1016/j.celrep.2023.112165_bib1) 2019; 10 Menezes (10.1016/j.celrep.2023.112165_bib4) 2016; 45 Takahashi (10.1016/j.celrep.2023.112165_bib34) 2012; 3 Ziegler-Heitbrock (10.1016/j.celrep.2023.112165_bib28) 2014; 289 Hamers (10.1016/j.celrep.2023.112165_bib30) 2019; 39 Reyes (10.1016/j.celrep.2023.112165_bib39) 1999; 80 Street (10.1016/j.celrep.2023.112165_bib16) 2018; 19 Shibuya (10.1016/j.celrep.2023.112165_bib35) 2021; 12 Bennett (10.1016/j.celrep.2023.112165_bib44) 1978; 75 Hirai (10.1016/j.celrep.2023.112165_bib22) 2006; 7 Liao (10.1016/j.celrep.2023.112165_bib60) 2013; 41 Yáñez (10.1016/j.celrep.2023.112165_bib10) 2017; 47 Gabrilovich (10.1016/j.celrep.2023.112165_bib45) 2007; 67 Dobin (10.1016/j.celrep.2023.112165_bib59) 2013; 29 Cao (10.1016/j.celrep.2023.112165_bib63) 2019; 566 Auffray (10.1016/j.celrep.2023.112165_bib6) 2007; 317 Hu (10.1016/j.celrep.2023.112165_bib20) 2021; 12 Ingersoll (10.1016/j.celrep.2023.112165_bib29) 2010; 115 Ashburner (10.1016/j.celrep.2023.112165_bib68) 2000; 25 Hahne (10.1016/j.celrep.2023.112165_bib55) 2009; 10 Kwok (10.1016/j.celrep.2023.112165_bib12) 2020; 53 Bassler (10.1016/j.celrep.2023.112165_bib27) 2019; 37 Geissmann (10.1016/j.celrep.2023.112165_bib5) 2003; 19 Ranaghan (10.1016/j.celrep.2023.112165_bib41) 1998; 20 Hegde (10.1016/j.celrep.2023.112165_bib46) 2021; 54 Mi (10.1016/j.celrep.2023.112165_bib72) 2019; 47 Sterneck (10.1016/j.celrep.2023.112165_bib52) 2006; 25 Emig (10.1016/j.celrep.2023.112165_bib67) 2010; 38 Zhu (10.1016/j.celrep.2023.112165_bib53) 2006; 103 Teh (10.1016/j.celrep.2023.112165_bib42) 2022; 8 Butler (10.1016/j.celrep.2023.112165_bib76) 2018; 36 Feng (10.1016/j.celrep.2023.112165_bib51) 2011; 186 Murray (10.1016/j.celrep.2023.112165_bib37) 2011; 11 Hock (10.1016/j.celrep.2023.112165_bib19) 2003; 18 Becht (10.1016/j.celrep.2023.112165_bib15) 2018; 37 Heinz (10.1016/j.celrep.2023.112165_bib65) 2010; 38 Parks (10.1016/j.celrep.2023.112165_bib69) 2006; 69 Nakatsu (10.1016/j.celrep.2023.112165_bib50) 2015; 290 Lohse (10.1016/j.celrep.2023.112165_bib58) 2012; 40 Guilliams (10.1016/j.celrep.2023.112165_bib8) 2018; 49 Corces (10.1016/j.celrep.2023.112165_bib75) 2016; 48 Chong (10.1016/j.celrep.2023.112165_bib43) 2016; 213 Stassen (10.1016/j.celrep.2023.112165_bib57) 2020; 36 Calzetti (10.1016/j.celrep.2023.112165_bib33) 2022; 23 Ikeda (10.1016/j.celrep.2023.112165_bib13) 2018; 3 Melsen (10.1016/j.celrep.2023.112165_bib71) 2020; 205 Sunderkötter (10.1016/j.celrep.2023.112165_bib3) 2004; 172 Love (10.1016/j.celrep.2023.112165_bib61) 2014; 15 Liu (10.1016/j.celrep.2023.112165_bib38) 2019; 178 Becht (10.1016/j.celrep.2023.112165_bib54) 2021; 7 Zhang (10.1016/j.celrep.2023.112165_bib21) 2017; 114 Hand (10.1016/j.celrep.2023.112165_bib70) 2001; 45 |
References_xml | – volume: 3 start-page: eaat0207 year: 2018 ident: bib13 article-title: Emergence of immunoregulatory Ym1(+)Ly6C(hi) monocytes during recovery phase of tissue injury publication-title: Sci. Immunol. contributor: fullname: Fukuyama – volume: 40 start-page: 4288 year: 2012 end-page: 4297 ident: bib66 article-title: Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation publication-title: Nucleic Acids Res. contributor: fullname: Smyth – volume: 37 start-page: 269 year: 2019 end-page: 293 ident: bib27 article-title: The myeloid cell compartment-cell by cell publication-title: Annu. Rev. Immunol. contributor: fullname: Schultze – volume: 47 start-page: 890 year: 2017 end-page: 902.e4 ident: bib10 article-title: Granulocyte-monocyte progenitors and monocyte-dendritic cell progenitors independently produce functionally distinct monocytes publication-title: Immunity contributor: fullname: Goodridge – volume: 18 start-page: 109 year: 2003 end-page: 120 ident: bib19 article-title: Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation publication-title: Immunity contributor: fullname: Orkin – volume: 49 start-page: 595 year: 2018 end-page: 613 ident: bib8 article-title: Developmental and functional heterogeneity of monocytes publication-title: Immunity contributor: fullname: Yona – volume: 51 start-page: 573 year: 2019 end-page: 589.e8 ident: bib14 article-title: Single-cell analysis of human mononuclear phagocytes reveals subset-defining markers and identifies circulating inflammatory dendritic cells publication-title: Immunity contributor: fullname: Lee – volume: 19 start-page: 477 year: 2018 ident: bib16 article-title: Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics publication-title: BMC Genomics contributor: fullname: Dudoit – volume: 121 start-page: 1839 year: 2013 end-page: 1849 ident: bib17 article-title: Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation publication-title: Blood contributor: fullname: Matsumoto – volume: 289 start-page: 135 year: 2014 end-page: 139 ident: bib28 article-title: Monocyte subsets in man and other species publication-title: Cell. Immunol. contributor: fullname: Ziegler-Heitbrock – volume: 115 start-page: e10 year: 2010 end-page: e19 ident: bib29 article-title: Comparison of gene expression profiles between human and mouse monocyte subsets publication-title: Blood contributor: fullname: Tacke – volume: 3 start-page: e437 year: 2012 ident: bib34 article-title: Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models publication-title: Cell Death Dis. contributor: fullname: Libert – volume: 47 start-page: D419 year: 2019 end-page: D426 ident: bib72 article-title: PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools publication-title: Nucleic Acids Res. contributor: fullname: Thomas – volume: 172 start-page: 4410 year: 2004 end-page: 4417 ident: bib3 article-title: Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response publication-title: J. Immunol. contributor: fullname: Leenen – volume: 537 start-page: 698 year: 2016 end-page: 702 ident: bib31 article-title: Single-cell analysis of mixed-lineage states leading to a binary cell fate choice publication-title: Nature contributor: fullname: Grimes – volume: 36 start-page: 411 year: 2018 end-page: 420 ident: bib76 article-title: Integrating single-cell transcriptomic data across different conditions, technologies, and species publication-title: Nat. Biotechnol. contributor: fullname: Satija – volume: 14 start-page: 821 year: 2013 end-page: 830 ident: bib9 article-title: Origin of monocytes and macrophages in a committed progenitor publication-title: Nat. Immunol. contributor: fullname: Feuerer – volume: 7 start-page: 732 year: 2006 end-page: 739 ident: bib22 article-title: C/EBPbeta is required for ‘emergency' granulopoiesis publication-title: Nat. Immunol. contributor: fullname: Tenen – volume: 497 start-page: 239 year: 2013 end-page: 243 ident: bib26 article-title: M-CSF instructs myeloid lineage fate in single haematopoietic stem cells publication-title: Nature contributor: fullname: Sieweke – volume: 45 start-page: 171 year: 2001 end-page: 186 ident: bib70 article-title: A simple generalisation of the area under the ROC curve for multiple class classification problems publication-title: Mach. Learn. contributor: fullname: Till – volume: 19 start-page: 71 year: 2003 end-page: 82 ident: bib5 article-title: Blood monocytes consist of two principal subsets with distinct migratory properties publication-title: Immunity contributor: fullname: Littman – volume: 12 start-page: 1023 year: 2021 ident: bib20 article-title: Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity publication-title: Cell Death Dis. contributor: fullname: Zhao – volume: 317 start-page: 666 year: 2007 end-page: 670 ident: bib6 article-title: Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior publication-title: Science contributor: fullname: Geissmann – volume: 38 start-page: 576 year: 2010 end-page: 589 ident: bib65 article-title: Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities publication-title: Mol. Cell contributor: fullname: Glass – volume: 541 start-page: 96 year: 2017 end-page: 101 ident: bib11 article-title: Identification of an atypical monocyte and committed progenitor involved in fibrosis publication-title: Nature contributor: fullname: Yoshioka – volume: 103 start-page: 18214 year: 2006 end-page: 18219 ident: bib53 article-title: Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Paul – volume: 45 start-page: 1205 year: 2016 end-page: 1218 ident: bib4 article-title: The heterogeneity of Ly6C(hi) monocytes controls their differentiation into iNOS(+) macrophages or monocyte-derived dendritic cells publication-title: Immunity contributor: fullname: Longhi – volume: 20 start-page: 49 year: 1998 end-page: 51 ident: bib41 article-title: Leukaemoid monocytosis in M4 AML following chemotherapy and G-CSF publication-title: Clin. Lab. Haematol. contributor: fullname: Morris – volume: 80 start-page: 229 year: 1999 end-page: 235 ident: bib39 article-title: Granulocyte colony-stimulating factor (G-CSF) transiently suppresses mitogen-stimulated T-cell proliferative response publication-title: Br. J. Cancer contributor: fullname: Alvarez-Mon – volume: 15 start-page: 550 year: 2014 ident: bib61 article-title: Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 publication-title: Genome Biol. contributor: fullname: Anders – volume: 12 start-page: 663115 year: 2021 ident: bib35 article-title: Immunoregulatory monocyte subset promotes metastasis associated with therapeutic intervention for primary tumor publication-title: Front. Immunol. contributor: fullname: Tamura – year: 2018 ident: bib56 article-title: UMAP: Uniform Manifold approximation and projection for dimension reduction publication-title: arXiv contributor: fullname: Melville – volume: 25 start-page: 25 year: 2000 end-page: 29 ident: bib68 article-title: Gene ontology: tool for the unification of biology. The Gene Ontology Consortium publication-title: Nat. Genet. contributor: fullname: Eppig – volume: 311 start-page: 83 year: 2006 end-page: 87 ident: bib7 article-title: A clonogenic bone marrow progenitor specific for macrophages and dendritic cells publication-title: Science contributor: fullname: Geissmann – volume: 37 start-page: 38 year: 2018 end-page: 44 ident: bib15 article-title: Dimensionality reduction for visualizing single-cell data using UMAP publication-title: Nat. Biotechnol. contributor: fullname: Newell – volume: 23 start-page: 679 year: 2022 end-page: 691 ident: bib33 article-title: CD66b(-)CD64(dim)CD115(-) cells in the human bone marrow represent neutrophil-committed progenitors publication-title: Nat. Immunol. contributor: fullname: Gasperini – volume: 69 start-page: 541 year: 2006 end-page: 551 ident: bib69 article-title: A new “Logicle” display method avoids deceptive effects of logarithmic scaling for low signals and compensated data publication-title: Cytometry A. contributor: fullname: Moore – volume: 54 start-page: 875 year: 2021 end-page: 884 ident: bib46 article-title: MDSC: markers, development, states, and unaddressed complexity publication-title: Immunity contributor: fullname: Merad – volume: 114 start-page: 3903 year: 2017 end-page: 3908 ident: bib21 article-title: Transcription factor Etv5 is essential for the maintenance of alveolar type II cells publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Wu – volume: 40 start-page: W622 year: 2012 end-page: W627 ident: bib58 article-title: RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics publication-title: Nucleic Acids Res. contributor: fullname: Usadel – volume: 367 start-page: 405 year: 2020 end-page: 411 ident: bib74 article-title: Single-cell transcriptional diversity is a hallmark of developmental potential publication-title: Science contributor: fullname: Cai – volume: 68 start-page: 687 year: 2019 end-page: 697 ident: bib47 article-title: Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates publication-title: Cancer Immunol. Immunother. contributor: fullname: Marini – volume: 356 start-page: eaah4573 year: 2017 ident: bib32 article-title: Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors publication-title: Science contributor: fullname: Lazo – volume: 7 start-page: eabg0505 year: 2021 ident: bib54 article-title: High-throughput single-cell quantification of hundreds of proteins using conventional flow cytometry and machine learning publication-title: Sci. Adv. contributor: fullname: Headley – volume: 29 start-page: 15 year: 2013 end-page: 21 ident: bib59 article-title: STAR: ultrafast universal RNA-seq aligner publication-title: Bioinformatics contributor: fullname: Gingeras – volume: 22 start-page: 301 year: 2021 end-page: 311 ident: bib49 article-title: A RUNX-CBFbeta-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes publication-title: Nat. Immunol. contributor: fullname: Nakajima – volume: 41 start-page: e108 year: 2013 ident: bib60 article-title: The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote publication-title: Nucleic Acids Res. contributor: fullname: Shi – volume: 67 start-page: 425 year: 2007 ident: bib45 article-title: The terminology issue for myeloid-derived suppressor cells publication-title: Cancer Res. contributor: fullname: Schreiber – volume: 205 start-page: 864 year: 2020 end-page: 871 ident: bib71 article-title: A comprehensive workflow for applying single-cell clustering and pseudotime analysis to flow cytometry data publication-title: J. Immunol. contributor: fullname: van den Akker – volume: 44 start-page: 450 year: 2016 end-page: 462 ident: bib36 article-title: Macrophages in tissue repair, regeneration, and fibrosis publication-title: Immunity contributor: fullname: Vannella – volume: 25 start-page: 1272 year: 2006 end-page: 1276 ident: bib52 article-title: Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis publication-title: Oncogene contributor: fullname: Smart – volume: 39 start-page: 25 year: 2019 end-page: 36 ident: bib30 article-title: Human monocyte heterogeneity as revealed by high-dimensional mass cytometry publication-title: Arterioscler. Thromb. Vasc. Biol. contributor: fullname: Nguyen – volume: 178 start-page: 1509 year: 2019 end-page: 1525.e19 ident: bib38 article-title: Fate mapping via Ms4a3-expression history traces monocyte-derived cells publication-title: Cell contributor: fullname: Dutertre – volume: 75 start-page: 5142 year: 1978 end-page: 5144 ident: bib44 article-title: Systemic bacillus Calmette-Guerin (BCG) activates natural suppressor cells publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Mitchell – volume: 38 start-page: W755 year: 2010 end-page: W762 ident: bib67 article-title: AltAnalyze and DomainGraph: analyzing and visualizing exon expression data publication-title: Nucleic Acids Res. contributor: fullname: Albrecht – volume: 26 start-page: 359 year: 2004 end-page: 362 ident: bib40 article-title: Transient atypical monocytosis mimic acute myelomonocytic leukemia in post-chemotherapy patients receiving G-CSF: report of two cases publication-title: Clin. Lab. Haematol. contributor: fullname: Ibrahim – volume: 213 start-page: 2293 year: 2016 end-page: 2314 ident: bib43 article-title: CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses publication-title: J. Exp. Med. contributor: fullname: Tan – volume: 48 start-page: 1193 year: 2016 end-page: 1203 ident: bib75 article-title: Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution publication-title: Nat. Genet. contributor: fullname: Greenleaf – volume: 566 start-page: 496 year: 2019 end-page: 502 ident: bib63 article-title: The single-cell transcriptional landscape of mammalian organogenesis publication-title: Nature contributor: fullname: Steemers – volume: 6 start-page: 423 year: 2015 ident: bib2 article-title: Blood monocytes and their subsets: established features and open questions publication-title: Front. Immunol. contributor: fullname: Ziegler-Heitbrock – volume: 8 start-page: eabj4641 year: 2022 ident: bib42 article-title: Transitional premonocytes emerge in the periphery for host defense against bacterial infections publication-title: Sci. Adv. contributor: fullname: Evrard – volume: 290 start-page: 24255 year: 2015 end-page: 24266 ident: bib50 article-title: Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the gamma subunit publication-title: J. Biol. Chem. contributor: fullname: Kamata – volume: 14 start-page: 309 year: 2017 end-page: 315 ident: bib24 article-title: Single-cell mRNA quantification and differential analysis with Census publication-title: Nat. Methods contributor: fullname: Trapnell – volume: 53 start-page: 303 year: 2020 end-page: 318.e5 ident: bib12 article-title: Combinatorial single-cell analyses of granulocyte-monocyte progenitor heterogeneity reveals an early uni-potent neutrophil progenitor publication-title: Immunity contributor: fullname: Tan – volume: 11 start-page: 723 year: 2011 end-page: 737 ident: bib37 article-title: Protective and pathogenic functions of macrophage subsets publication-title: Nat. Rev. Immunol. contributor: fullname: Wynn – volume: 186 start-page: 1458 year: 2011 end-page: 1466 ident: bib51 article-title: IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools publication-title: J. Immunol. contributor: fullname: Morse – volume: 5 start-page: 602 year: 2022 ident: bib62 article-title: TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq publication-title: Commun. Biol. contributor: fullname: Sawabata – volume: 184 start-page: 3573 year: 2021 end-page: 3587.e29 ident: bib23 article-title: Integrated analysis of multimodal single-cell data publication-title: Cell contributor: fullname: Zager – volume: 36 start-page: 2778 year: 2020 end-page: 2786 ident: bib57 article-title: PARC: ultrafast and accurate clustering of phenotypic data of millions of single cells publication-title: Bioinformatics contributor: fullname: Tsia – volume: 31 start-page: 545 year: 2015 end-page: 554 ident: bib73 article-title: Statistical significance of variables driving systematic variation in high-dimensional data publication-title: Bioinformatics contributor: fullname: Storey – volume: 216 start-page: 2150 year: 2019 end-page: 2169 ident: bib48 article-title: Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs publication-title: J. Exp. Med. contributor: fullname: Zhou – volume: 10 start-page: 1642 year: 2019 ident: bib1 article-title: The ontogeny of monocyte subsets publication-title: Front. Immunol. contributor: fullname: Goodridge – volume: 5 start-page: 4978 year: 2014 ident: bib18 article-title: IRF8 inhibits C/EBPalpha activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils publication-title: Nat. Commun. contributor: fullname: Ryo – volume: 10 start-page: 106 year: 2009 ident: bib55 article-title: flowCore: a Bioconductor package for high throughput flow cytometry publication-title: BMC Bioinformatics contributor: fullname: Gentleman – volume: 19 start-page: 159 year: 2022 end-page: 170 ident: bib25 article-title: CellRank for directed single-cell fate mapping publication-title: Nat. Methods contributor: fullname: Schiller – volume: 9 start-page: 357 year: 2012 end-page: 359 ident: bib64 article-title: Fast gapped-read alignment with Bowtie 2 publication-title: Nat. Methods contributor: fullname: Salzberg – volume: 3 start-page: e437 year: 2012 ident: 10.1016/j.celrep.2023.112165_bib34 article-title: Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models publication-title: Cell Death Dis. doi: 10.1038/cddis.2012.176 contributor: fullname: Takahashi – volume: 44 start-page: 450 year: 2016 ident: 10.1016/j.celrep.2023.112165_bib36 article-title: Macrophages in tissue repair, regeneration, and fibrosis publication-title: Immunity doi: 10.1016/j.immuni.2016.02.015 contributor: fullname: Wynn – year: 2018 ident: 10.1016/j.celrep.2023.112165_bib56 article-title: UMAP: Uniform Manifold approximation and projection for dimension reduction publication-title: arXiv contributor: fullname: McInnes – volume: 54 start-page: 875 year: 2021 ident: 10.1016/j.celrep.2023.112165_bib46 article-title: MDSC: markers, development, states, and unaddressed complexity publication-title: Immunity doi: 10.1016/j.immuni.2021.04.004 contributor: fullname: Hegde – volume: 23 start-page: 679 year: 2022 ident: 10.1016/j.celrep.2023.112165_bib33 article-title: CD66b(-)CD64(dim)CD115(-) cells in the human bone marrow represent neutrophil-committed progenitors publication-title: Nat. Immunol. doi: 10.1038/s41590-022-01189-z contributor: fullname: Calzetti – volume: 41 start-page: e108 year: 2013 ident: 10.1016/j.celrep.2023.112165_bib60 article-title: The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkt214 contributor: fullname: Liao – volume: 172 start-page: 4410 year: 2004 ident: 10.1016/j.celrep.2023.112165_bib3 article-title: Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response publication-title: J. Immunol. doi: 10.4049/jimmunol.172.7.4410 contributor: fullname: Sunderkötter – volume: 37 start-page: 269 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib27 article-title: The myeloid cell compartment-cell by cell publication-title: Annu. Rev. Immunol. doi: 10.1146/annurev-immunol-042718-041728 contributor: fullname: Bassler – volume: 20 start-page: 49 year: 1998 ident: 10.1016/j.celrep.2023.112165_bib41 article-title: Leukaemoid monocytosis in M4 AML following chemotherapy and G-CSF publication-title: Clin. Lab. Haematol. doi: 10.1046/j.1365-2257.1998.00083.x contributor: fullname: Ranaghan – volume: 25 start-page: 25 year: 2000 ident: 10.1016/j.celrep.2023.112165_bib68 article-title: Gene ontology: tool for the unification of biology. The Gene Ontology Consortium publication-title: Nat. Genet. doi: 10.1038/75556 contributor: fullname: Ashburner – volume: 114 start-page: 3903 year: 2017 ident: 10.1016/j.celrep.2023.112165_bib21 article-title: Transcription factor Etv5 is essential for the maintenance of alveolar type II cells publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1621177114 contributor: fullname: Zhang – volume: 80 start-page: 229 year: 1999 ident: 10.1016/j.celrep.2023.112165_bib39 article-title: Granulocyte colony-stimulating factor (G-CSF) transiently suppresses mitogen-stimulated T-cell proliferative response publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6690344 contributor: fullname: Reyes – volume: 10 start-page: 1642 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib1 article-title: The ontogeny of monocyte subsets publication-title: Front. Immunol. doi: 10.3389/fimmu.2019.01642 contributor: fullname: Wolf – volume: 11 start-page: 723 year: 2011 ident: 10.1016/j.celrep.2023.112165_bib37 article-title: Protective and pathogenic functions of macrophage subsets publication-title: Nat. Rev. Immunol. doi: 10.1038/nri3073 contributor: fullname: Murray – volume: 10 start-page: 106 year: 2009 ident: 10.1016/j.celrep.2023.112165_bib55 article-title: flowCore: a Bioconductor package for high throughput flow cytometry publication-title: BMC Bioinformatics doi: 10.1186/1471-2105-10-106 contributor: fullname: Hahne – volume: 19 start-page: 71 year: 2003 ident: 10.1016/j.celrep.2023.112165_bib5 article-title: Blood monocytes consist of two principal subsets with distinct migratory properties publication-title: Immunity doi: 10.1016/S1074-7613(03)00174-2 contributor: fullname: Geissmann – volume: 103 start-page: 18214 year: 2006 ident: 10.1016/j.celrep.2023.112165_bib53 article-title: Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.0608981103 contributor: fullname: Zhu – volume: 5 start-page: 4978 year: 2014 ident: 10.1016/j.celrep.2023.112165_bib18 article-title: IRF8 inhibits C/EBPalpha activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils publication-title: Nat. Commun. doi: 10.1038/ncomms5978 contributor: fullname: Kurotaki – volume: 290 start-page: 24255 year: 2015 ident: 10.1016/j.celrep.2023.112165_bib50 article-title: Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the gamma subunit publication-title: J. Biol. Chem. doi: 10.1074/jbc.M115.658559 contributor: fullname: Nakatsu – volume: 47 start-page: 890 year: 2017 ident: 10.1016/j.celrep.2023.112165_bib10 article-title: Granulocyte-monocyte progenitors and monocyte-dendritic cell progenitors independently produce functionally distinct monocytes publication-title: Immunity doi: 10.1016/j.immuni.2017.10.021 contributor: fullname: Yáñez – volume: 541 start-page: 96 year: 2017 ident: 10.1016/j.celrep.2023.112165_bib11 article-title: Identification of an atypical monocyte and committed progenitor involved in fibrosis publication-title: Nature doi: 10.1038/nature20611 contributor: fullname: Satoh – volume: 37 start-page: 38 year: 2018 ident: 10.1016/j.celrep.2023.112165_bib15 article-title: Dimensionality reduction for visualizing single-cell data using UMAP publication-title: Nat. Biotechnol. doi: 10.1038/nbt.4314 contributor: fullname: Becht – volume: 25 start-page: 1272 year: 2006 ident: 10.1016/j.celrep.2023.112165_bib52 article-title: Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis publication-title: Oncogene doi: 10.1038/sj.onc.1209144 contributor: fullname: Sterneck – volume: 497 start-page: 239 year: 2013 ident: 10.1016/j.celrep.2023.112165_bib26 article-title: M-CSF instructs myeloid lineage fate in single haematopoietic stem cells publication-title: Nature doi: 10.1038/nature12026 contributor: fullname: Mossadegh-Keller – volume: 31 start-page: 545 year: 2015 ident: 10.1016/j.celrep.2023.112165_bib73 article-title: Statistical significance of variables driving systematic variation in high-dimensional data publication-title: Bioinformatics doi: 10.1093/bioinformatics/btu674 contributor: fullname: Chung – volume: 9 start-page: 357 year: 2012 ident: 10.1016/j.celrep.2023.112165_bib64 article-title: Fast gapped-read alignment with Bowtie 2 publication-title: Nat. Methods doi: 10.1038/nmeth.1923 contributor: fullname: Langmead – volume: 537 start-page: 698 year: 2016 ident: 10.1016/j.celrep.2023.112165_bib31 article-title: Single-cell analysis of mixed-lineage states leading to a binary cell fate choice publication-title: Nature doi: 10.1038/nature19348 contributor: fullname: Olsson – volume: 566 start-page: 496 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib63 article-title: The single-cell transcriptional landscape of mammalian organogenesis publication-title: Nature doi: 10.1038/s41586-019-0969-x contributor: fullname: Cao – volume: 12 start-page: 1023 year: 2021 ident: 10.1016/j.celrep.2023.112165_bib20 article-title: Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity publication-title: Cell Death Dis. doi: 10.1038/s41419-021-04308-0 contributor: fullname: Hu – volume: 14 start-page: 821 year: 2013 ident: 10.1016/j.celrep.2023.112165_bib9 article-title: Origin of monocytes and macrophages in a committed progenitor publication-title: Nat. Immunol. doi: 10.1038/ni.2638 contributor: fullname: Hettinger – volume: 38 start-page: 576 year: 2010 ident: 10.1016/j.celrep.2023.112165_bib65 article-title: Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities publication-title: Mol. Cell doi: 10.1016/j.molcel.2010.05.004 contributor: fullname: Heinz – volume: 39 start-page: 25 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib30 article-title: Human monocyte heterogeneity as revealed by high-dimensional mass cytometry publication-title: Arterioscler. Thromb. Vasc. Biol. doi: 10.1161/ATVBAHA.118.311022 contributor: fullname: Hamers – volume: 213 start-page: 2293 year: 2016 ident: 10.1016/j.celrep.2023.112165_bib43 article-title: CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses publication-title: J. Exp. Med. doi: 10.1084/jem.20160800 contributor: fullname: Chong – volume: 216 start-page: 2150 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib48 article-title: Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs publication-title: J. Exp. Med. doi: 10.1084/jem.20181952 contributor: fullname: Mastio – volume: 121 start-page: 1839 year: 2013 ident: 10.1016/j.celrep.2023.112165_bib17 article-title: Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation publication-title: Blood doi: 10.1182/blood-2012-06-437863 contributor: fullname: Kurotaki – volume: 47 start-page: D419 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib72 article-title: PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools publication-title: Nucleic Acids Res. doi: 10.1093/nar/gky1038 contributor: fullname: Mi – volume: 184 start-page: 3573 year: 2021 ident: 10.1016/j.celrep.2023.112165_bib23 article-title: Integrated analysis of multimodal single-cell data publication-title: Cell doi: 10.1016/j.cell.2021.04.048 contributor: fullname: Hao – volume: 40 start-page: W622 year: 2012 ident: 10.1016/j.celrep.2023.112165_bib58 article-title: RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics publication-title: Nucleic Acids Res. doi: 10.1093/nar/gks540 contributor: fullname: Lohse – volume: 12 start-page: 663115 year: 2021 ident: 10.1016/j.celrep.2023.112165_bib35 article-title: Immunoregulatory monocyte subset promotes metastasis associated with therapeutic intervention for primary tumor publication-title: Front. Immunol. doi: 10.3389/fimmu.2021.663115 contributor: fullname: Shibuya – volume: 29 start-page: 15 year: 2013 ident: 10.1016/j.celrep.2023.112165_bib59 article-title: STAR: ultrafast universal RNA-seq aligner publication-title: Bioinformatics doi: 10.1093/bioinformatics/bts635 contributor: fullname: Dobin – volume: 67 start-page: 425 year: 2007 ident: 10.1016/j.celrep.2023.112165_bib45 article-title: The terminology issue for myeloid-derived suppressor cells publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-3037 contributor: fullname: Gabrilovich – volume: 186 start-page: 1458 year: 2011 ident: 10.1016/j.celrep.2023.112165_bib51 article-title: IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools publication-title: J. Immunol. doi: 10.4049/jimmunol.1001950 contributor: fullname: Feng – volume: 51 start-page: 573 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib14 article-title: Single-cell analysis of human mononuclear phagocytes reveals subset-defining markers and identifies circulating inflammatory dendritic cells publication-title: Immunity doi: 10.1016/j.immuni.2019.08.008 contributor: fullname: Dutertre – volume: 8 start-page: eabj4641 year: 2022 ident: 10.1016/j.celrep.2023.112165_bib42 article-title: Transitional premonocytes emerge in the periphery for host defense against bacterial infections publication-title: Sci. Adv. doi: 10.1126/sciadv.abj4641 contributor: fullname: Teh – volume: 48 start-page: 1193 year: 2016 ident: 10.1016/j.celrep.2023.112165_bib75 article-title: Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution publication-title: Nat. Genet. doi: 10.1038/ng.3646 contributor: fullname: Corces – volume: 367 start-page: 405 year: 2020 ident: 10.1016/j.celrep.2023.112165_bib74 article-title: Single-cell transcriptional diversity is a hallmark of developmental potential publication-title: Science doi: 10.1126/science.aax0249 contributor: fullname: Gulati – volume: 317 start-page: 666 year: 2007 ident: 10.1016/j.celrep.2023.112165_bib6 article-title: Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior publication-title: Science doi: 10.1126/science.1142883 contributor: fullname: Auffray – volume: 311 start-page: 83 year: 2006 ident: 10.1016/j.celrep.2023.112165_bib7 article-title: A clonogenic bone marrow progenitor specific for macrophages and dendritic cells publication-title: Science doi: 10.1126/science.1117729 contributor: fullname: Fogg – volume: 26 start-page: 359 year: 2004 ident: 10.1016/j.celrep.2023.112165_bib40 article-title: Transient atypical monocytosis mimic acute myelomonocytic leukemia in post-chemotherapy patients receiving G-CSF: report of two cases publication-title: Clin. Lab. Haematol. doi: 10.1111/j.1365-2257.2004.00628.x contributor: fullname: Liu – volume: 6 start-page: 423 year: 2015 ident: 10.1016/j.celrep.2023.112165_bib2 article-title: Blood monocytes and their subsets: established features and open questions publication-title: Front. Immunol. doi: 10.3389/fimmu.2015.00423 contributor: fullname: Ziegler-Heitbrock – volume: 3 start-page: eaat0207 year: 2018 ident: 10.1016/j.celrep.2023.112165_bib13 article-title: Emergence of immunoregulatory Ym1(+)Ly6C(hi) monocytes during recovery phase of tissue injury publication-title: Sci. Immunol. doi: 10.1126/sciimmunol.aat0207 contributor: fullname: Ikeda – volume: 289 start-page: 135 year: 2014 ident: 10.1016/j.celrep.2023.112165_bib28 article-title: Monocyte subsets in man and other species publication-title: Cell. Immunol. doi: 10.1016/j.cellimm.2014.03.019 contributor: fullname: Ziegler-Heitbrock – volume: 356 start-page: eaah4573 year: 2017 ident: 10.1016/j.celrep.2023.112165_bib32 article-title: Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors publication-title: Science doi: 10.1126/science.aah4573 contributor: fullname: Villani – volume: 69 start-page: 541 year: 2006 ident: 10.1016/j.celrep.2023.112165_bib69 article-title: A new “Logicle” display method avoids deceptive effects of logarithmic scaling for low signals and compensated data publication-title: Cytometry A. doi: 10.1002/cyto.a.20258 contributor: fullname: Parks – volume: 178 start-page: 1509 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib38 article-title: Fate mapping via Ms4a3-expression history traces monocyte-derived cells publication-title: Cell doi: 10.1016/j.cell.2019.08.009 contributor: fullname: Liu – volume: 38 start-page: W755 year: 2010 ident: 10.1016/j.celrep.2023.112165_bib67 article-title: AltAnalyze and DomainGraph: analyzing and visualizing exon expression data publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkq405 contributor: fullname: Emig – volume: 22 start-page: 301 year: 2021 ident: 10.1016/j.celrep.2023.112165_bib49 article-title: A RUNX-CBFbeta-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes publication-title: Nat. Immunol. doi: 10.1038/s41590-021-00871-y contributor: fullname: Murakami – volume: 18 start-page: 109 year: 2003 ident: 10.1016/j.celrep.2023.112165_bib19 article-title: Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation publication-title: Immunity doi: 10.1016/S1074-7613(02)00501-0 contributor: fullname: Hock – volume: 36 start-page: 2778 year: 2020 ident: 10.1016/j.celrep.2023.112165_bib57 article-title: PARC: ultrafast and accurate clustering of phenotypic data of millions of single cells publication-title: Bioinformatics doi: 10.1093/bioinformatics/btaa042 contributor: fullname: Stassen – volume: 19 start-page: 159 year: 2022 ident: 10.1016/j.celrep.2023.112165_bib25 article-title: CellRank for directed single-cell fate mapping publication-title: Nat. Methods doi: 10.1038/s41592-021-01346-6 contributor: fullname: Lange – volume: 5 start-page: 602 year: 2022 ident: 10.1016/j.celrep.2023.112165_bib62 article-title: TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq publication-title: Commun. Biol. doi: 10.1038/s42003-022-03536-0 contributor: fullname: Shichino – volume: 7 start-page: 732 year: 2006 ident: 10.1016/j.celrep.2023.112165_bib22 article-title: C/EBPbeta is required for ‘emergency' granulopoiesis publication-title: Nat. Immunol. doi: 10.1038/ni1354 contributor: fullname: Hirai – volume: 53 start-page: 303 year: 2020 ident: 10.1016/j.celrep.2023.112165_bib12 article-title: Combinatorial single-cell analyses of granulocyte-monocyte progenitor heterogeneity reveals an early uni-potent neutrophil progenitor publication-title: Immunity doi: 10.1016/j.immuni.2020.06.005 contributor: fullname: Kwok – volume: 7 start-page: eabg0505 year: 2021 ident: 10.1016/j.celrep.2023.112165_bib54 article-title: High-throughput single-cell quantification of hundreds of proteins using conventional flow cytometry and machine learning publication-title: Sci. Adv. doi: 10.1126/sciadv.abg0505 contributor: fullname: Becht – volume: 49 start-page: 595 year: 2018 ident: 10.1016/j.celrep.2023.112165_bib8 article-title: Developmental and functional heterogeneity of monocytes publication-title: Immunity doi: 10.1016/j.immuni.2018.10.005 contributor: fullname: Guilliams – volume: 68 start-page: 687 year: 2019 ident: 10.1016/j.celrep.2023.112165_bib47 article-title: Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates publication-title: Cancer Immunol. Immunother. doi: 10.1007/s00262-019-02302-2 contributor: fullname: Cassetta – volume: 45 start-page: 171 year: 2001 ident: 10.1016/j.celrep.2023.112165_bib70 article-title: A simple generalisation of the area under the ROC curve for multiple class classification problems publication-title: Mach. Learn. doi: 10.1023/A:1010920819831 contributor: fullname: Hand – volume: 19 start-page: 477 year: 2018 ident: 10.1016/j.celrep.2023.112165_bib16 article-title: Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics publication-title: BMC Genomics doi: 10.1186/s12864-018-4772-0 contributor: fullname: Street – volume: 75 start-page: 5142 year: 1978 ident: 10.1016/j.celrep.2023.112165_bib44 article-title: Systemic bacillus Calmette-Guerin (BCG) activates natural suppressor cells publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.75.10.5142 contributor: fullname: Bennett – volume: 45 start-page: 1205 year: 2016 ident: 10.1016/j.celrep.2023.112165_bib4 article-title: The heterogeneity of Ly6C(hi) monocytes controls their differentiation into iNOS(+) macrophages or monocyte-derived dendritic cells publication-title: Immunity doi: 10.1016/j.immuni.2016.12.001 contributor: fullname: Menezes – volume: 115 start-page: e10 year: 2010 ident: 10.1016/j.celrep.2023.112165_bib29 article-title: Comparison of gene expression profiles between human and mouse monocyte subsets publication-title: Blood doi: 10.1182/blood-2009-07-235028 contributor: fullname: Ingersoll – volume: 15 start-page: 550 year: 2014 ident: 10.1016/j.celrep.2023.112165_bib61 article-title: Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 publication-title: Genome Biol. doi: 10.1186/s13059-014-0550-8 contributor: fullname: Love – volume: 36 start-page: 411 year: 2018 ident: 10.1016/j.celrep.2023.112165_bib76 article-title: Integrating single-cell transcriptomic data across different conditions, technologies, and species publication-title: Nat. Biotechnol. doi: 10.1038/nbt.4096 contributor: fullname: Butler – volume: 14 start-page: 309 year: 2017 ident: 10.1016/j.celrep.2023.112165_bib24 article-title: Single-cell mRNA quantification and differential analysis with Census publication-title: Nat. Methods doi: 10.1038/nmeth.4150 contributor: fullname: Qiu – volume: 40 start-page: 4288 year: 2012 ident: 10.1016/j.celrep.2023.112165_bib66 article-title: Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation publication-title: Nucleic Acids Res. doi: 10.1093/nar/gks042 contributor: fullname: McCarthy – volume: 205 start-page: 864 year: 2020 ident: 10.1016/j.celrep.2023.112165_bib71 article-title: A comprehensive workflow for applying single-cell clustering and pseudotime analysis to flow cytometry data publication-title: J. Immunol. doi: 10.4049/jimmunol.1901530 contributor: fullname: Melsen |
SSID | ssj0000601194 |
Score | 2.4914753 |
Snippet | Inflammatory stimuli cause a state of emergency myelopoiesis leading to neutrophil-like monocyte expansion. However, their function, the committed precursors,... |
SourceID | doaj proquest crossref pubmed elsevier |
SourceType | Open Website Aggregation Database Index Database Publisher |
StartPage | 112165 |
SubjectTerms | Animals Cell Differentiation CP: Immunology CXCR1 demand-adapted myelopoiesis emergency myelopoiesis G-CSF Granulocyte Colony-Stimulating Factor Humans machine learning Mice monocyte Monocytes - physiology Myelopoiesis neutrophil-like monocyte Neutrophils ontogeny Ym1 |
SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1La9wwEBYhEMiltGnSbtIUFXI1sR62tce2JIRCe0ohN6HHiLokdvB6D3vsP8-MtQ7bQ8mlV1vYg-b1Cc18w9gF3awhbqiKSFSfunSqcEtqziEukjI5lxlvvv-ob37qb3fV3c6oL6oJy_TAeeMuMcpCVNpJSE4HRLfCOFHHWqdlElrk6FvKncNUjsHEZUZXylJSzZbUzdw3NxV3BbgfgOgqpaImGkG5ZScvTfT9f6Wnf8HPKQ1dv2avtviRf85yv2F70B2xgzxRcvOW_UG1cyDSYt7Behz6x1_tfYFW9dCOiC05lWMBefGw4s7DgJlqxLXzmBR09xF42409b6lxpB_yqPp-2HC01z5sEJny3NrIYe7c5A8bKjzq8dDdro7Z7fXV7debYjtloQi60WORlrGCIGU0LpZEzZPq0tMoGtWgt_rGqwgmNhqCEUKJYJxpAA91yntpQqVO2H7Xd_CecYi6KkMKCNqVBolvfSVT8qZULrjgF6yYt9g-Zi4NOxeZ_bZZJZZUYrNKFuwL6eF5LTFhTw_QPuzWPuxL9rFgzaxFuwUVGSzgp9oXfv9pVrpFn6OLFNdBv15Z2RhRIzYy9YK9y9bwLKSilpuqkqf_Q_gzdkgCUc2bNB_Y_jis4RxB0Og_Tvb-BIXKBQk priority: 102 providerName: Directory of Open Access Journals – databaseName: Elsevier Free Content dbid: IXB link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELaqSkhcEJTXFoqMxDXa-JHEe6QVVUFqLxRpb5btjCGoTVbZ7GGP_HNm4mRFDwiJYxwndjxjz-d45hvGPtDJGuKGIquJ6lPnTmVuRcE5xEWSR-cS4831TXn1TX9ZF-sjdjHHwpBb5bT2pzV9XK2nkuU0mstN0yy_Sty7oHWqEETnRHOI67AqctLyz-vzw38W4hsRYz5Eqp_RA3ME3ejmFeCuByKulIrCaQRZmT8s1Ejk_8BQ_Q2Ijgbp8il7MiFJ_jF19hk7gvaEPUq5JffP2S9UAA5EX8xb2A19t_nR3GX4mffNgCiTk2MW0Hzut9x56NFmDVh3TpiCE38A3rRDxxsKIen6lLS-6_ccNbcLe8SoPAU5cphjOPn9nlyQOtx-N9sX7Pby0-3FVTblW8iCrvSQxVVdQJCyNq7OiaQnlrmnpDSqwgH2lVc1mLrSEIwQSgTjTAW4vVPeSxMK9ZIdt10LrxmHWhd5iAHhu9Ig8a4vZIze5MoFF_yCZfMQ201i1bCzu9lPm0RiSSQ2iWTBzkkOh7rEiT0WdP13OymFRXsMtdJOQnQ64D5IGCfKutRxFYUWcsGqWYr2gYrhq5p_NP9-FrrF2UdHKq6Fbre1sjKiRJRkygV7lbTh0ElFwTdFIU__u9037DFdkcubNG_Z8dDv4Awx0ODfjUr-G9hgBlw priority: 102 providerName: Elsevier |
Title | The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis |
URI | https://dx.doi.org/10.1016/j.celrep.2023.112165 https://www.ncbi.nlm.nih.gov/pubmed/36862552 https://search.proquest.com/docview/2781621886 https://doaj.org/article/341ed34a2efa4c75818a16d64f9f1412 |
Volume | 42 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1Lb9QwELZKEagXxJvlURmJa1BiO4n3gBBFVAWpnFppb5btTCBomxRvVmqO_efMxElRJVZccoidOPLMeD7HM98w9o5O1hA35ElFVJ8qtTKxS0rOIS6StLY2Mt6cfi9OztW3Vb7aY3PN1mkCN__c2lE9qfOwfn_1e_iIBv_hb6yWh3UAYp8UknJisiK_w-4K9I0U5HU6Af64NhPHmZpz6HY8fMDuS8qcyHNxy12NrP63vNYuVDp6p-OH7MEEK_mnqAeP2B60j9m9WGhyeMKuURs4EJcxb2Hbh-7yZ7NOUNkumh4hJ6coLSDjDhtuHQR0YD32naun4CrQA2_avuMN5ZN0IVaw78LAUY07PyBg5THjkcOc0MkvBopH6nAv3myesrPjL2efT5Kp-ELiVan6pF5WOXghKm2rlBh76iJ1VKFGlmjErnSyAl2VCrzOMpl5bXUJuNeTzgntc_mM7bddCy8Yh0rlqa89YnmpQGCry0VdO51K6613C5bMU2wuI8WGmWPPfpkoHUPSMVE6C3ZEcrjpSwTZ440u_DCTvRl0zlBJZQXUVnncFGXaZkVVqHpZZyoTC1bOUjQT1ogYAl_V_Gf4t7PQDZoina_YFrrtxohSZwVCJl0s2POoDTcfOevTy50tr9gBjULxbUK_Zvt92MIbBDy9Oxx_FOD16-rocNTnPz7sAaw |
link.rule.ids | 314,780,784,864,2102,2221,3506,24318,27924,27925,45874 |
linkProvider | Scholars Portal |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELZKEYIL4s3yNBLXaONHEu-RVlQttL2wSHuzbGdCg9pklc0e9sg_ZyZOVvSAkLjacex4xp7P8cw3jH2kmzXEDVlSEtWnTp1K3IKCc4iLJK2ci4w3F5f56Xf9ZZWtDtjxFAtDbpXj3h_39GG3Hkvm42zO13U9_ybx7ILWqUAQnRLN4R12V2emIAL9s9XR_kcLEY6IISEiNUioxRRCN_h5BbjugJgrpaJ4GkFm5g8TNTD537JUf0Oig0U6ecQejlCSf4qjfcwOoHnC7sXkkrun7BdqAAfiL-YNbPuuXV_V1wl-503dI8zk5JkFtKC7DXceOjRaPT47ZUzBld8Dr5u-5TXFkLRdzFrfdjuOqtuGHYJUHqMcOUxBnPxmRz5ILZ6_680ztjz5vDw-TcaEC0nQhe6TalFmEKQsjStTYump8tRTVhpV4Az7wqsSTFloCEYIJYJxpgA83ynvpQmZes4Om7aBl4xDqbM0VAHxu9IgsdZnsqq8SZULLvgZS6YptutIq2Enf7OfNorEkkhsFMmMHZEc9s8SKfZQ0HY_7KgVFg0ylEo7CZXTAQ9CwjiRl7muFpXQQs5YMUnR3tIxfFX9j-4_TEK3uPzoTsU10G43VhZG5AiTTD5jL6I27AepKPomy-Sr_-73Pbt_urw4t-dnl19fswdUQ_5v0rxhh323hbcIiHr_blD43yMKCYU |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+early+neutrophil-committed+progenitors+aberrantly+differentiate+into+immunoregulatory+monocytes+during+emergency+myelopoiesis&rft.jtitle=Cell+reports+%28Cambridge%29&rft.au=Ikeda%2C+Naoki&rft.au=Kubota%2C+Hiroaki&rft.au=Suzuki%2C+Risa&rft.au=Morita%2C+Mitsuki&rft.date=2023-03-28&rft.eissn=2211-1247&rft.volume=42&rft.issue=3&rft.spage=112165&rft_id=info:doi/10.1016%2Fj.celrep.2023.112165&rft_id=info%3Apmid%2F36862552&rft.externalDocID=36862552 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2211-1247&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2211-1247&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2211-1247&client=summon |