TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation - Chiramel, Abhilash I.; Meyerson, Nicholas R.; McNally, Kristin L.; Broeckel, Rebecca M.; Montoya, Vanessa R.; Méndez-Solís, Omayra; Robertson, Shelly J.; Sturdevant, Gail L.; Lubick, Kirk J.; Nair, Vinod; Youseff, Brian H.; Ireland, Robin M.; et al. (Cell reports (Cambridge), 2019)
Keywords: Animals; Antiviral Restriction Factors; Cats; Chlorocebus aethiops; Dendritic Cells - metabolism; Dendritic Cells - virology; Flavivirus - pathogenicity; Flavivirus - physiology; Flavivirus Infections - metabolism; Flavivirus Infections - virology; HEK293 Cells; Humans; Peptide Hydrolases - metabolism; Proteasome Endopeptidase Complex - metabolism; Protein Binding; Proteolysis; Substrate Specificity; Tripartite Motif Proteins - metabolism; Ubiquitin-Protein Ligases - metabolism; Ubiquitination; Vero Cells; Viral Proteins - metabolism; Virus Replication; TRIM5α; retrovirus; restriction factor; interferon; interferon stimulated genes; flavivirus; tick-borne encephalitis virus