Nuclear positioning during development: Pushing, pulling and flowing

• Published in: Seminars in cell & developmental biology Vol. 120; pp. 10 - 21
• Main Authors: Deshpande, Ojas, Telley, Ivo A.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2021
• Subjects: Animals; Cell Nucleus - genetics; Cytoplasmic flow; Cytoskeleton; Drosophila; Effects of scaling; Embryo size; Microtubule; Nuclear division; Syncytial cleavage; Effects of scaling; Nuclear division; Embryo size; Cytoskeleton; Microtubule; Syncytial cleavage; Cytoplasmic flow

The positioning of the nucleus, the central organelle of the cell, is an active and regulated process crucially linked to cell cycle, differentiation, migration, and polarity. Alterations in positioning have been correlated with cell and tissue function deficiency and genetic or chemical manipulatio...