Phase-Specific Microstimulation Differentially Modulates Beta Oscillations and Affects Behavior

• Published in: Cell reports (Cambridge) Vol. 30; no. 8; pp. 2555 - 2566.e3
• Main Authors: Peles, Oren, Werner-Reiss, Uri, Bergman, Hagai, Israel, Zvi, Vaadia, Eilon
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 25.02.2020; Elsevier
• Subjects: Action Potentials - physiology; Animals; Behavior, Animal - physiology; Beta oscillations; Beta Rhythm - physiology; brain-machine interface; Conditioning, Operant; Electric Stimulation; Female; local field potential; Macaca mulatta; microsimulation; motor cortex; non-human primates; operant conditioning; local field potential; motor cortex; operant conditioning; non-human primates; Beta oscillations; brain-machine interface; microsimulation

It is widely accepted that Beta-band oscillations play a role in sensorimotor behavior. To further explore this role, we developed a hybrid platform to combine neural operant conditioning and phase-specific intracortical microstimulation (ICMS). We trained monkeys, implanted with 96 electrode arrays...