Salmonella enterica serovar Typhi influences inflammation and autophagy in macrophages

• Published in: Brazilian journal of microbiology Vol. 53; no. 2; pp. 525 - 534
• Main Authors: Wang, Huiyun, Xie, Zhongyi, Yang, Fanfan, Wang, Yurou, Jiang, Haiqiang, Huang, Xinxiang, Zhang, Ying
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.06.2022; Springer Nature B.V
• Subjects: Autophagy; Bacterial and Fungal Pathogenesis - Research Paper; Biomedical and Life Sciences; Disseminated infection; Food Microbiology; Humans; Immune response; Infections; Inflammation; Life Sciences; Macrophages; Macrophages - microbiology; Medical Microbiology; Microbial Ecology; Microbial Genetics and Genomics; Microbiology; mRNA; Mycology; NF-kappa B - genetics; NF-κB protein; Salmonella; Salmonella enterica; Salmonella typhi - genetics; Signal transduction; Signaling; Western blotting; Inflammation; Typhi; Autophagy; NF-κB signaling pathway; Transcriptome; S. Typhi

Salmonella enterica serovar Typhi ( S. Typhi) is a human enteropathogen that can survive in macrophages and cause systemic infection. Autophagy and inflammation are two important immune responses of macrophages that contribute to the elimination of pathogens. However, Salmonella has derived many str...