The Structural Model: a theory linking connections, plasticity, pathology, development and evolution of the cerebral cortex

• Published in: Brain Structure and Function Vol. 224; no. 3; pp. 985 - 1008
• Main Authors: García-Cabezas, Miguel Ángel, Zikopoulos, Basilis, Barbas, Helen
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2019; Springer Nature B.V
• Subjects: Animals; Biological Evolution; Biomedical and Life Sciences; Biomedicine; Cell Biology; Cerebral cortex; Cerebral Cortex - cytology; Cerebral Cortex - pathology; Cerebral Cortex - physiology; Developmental plasticity; Humans; Hypotheses; Mental disorders; Models, Neurological; Neural Pathways - physiology; Neurology; Neuronal Plasticity - physiology; Neuroplasticity; Neurosciences; Ontogeny; Phylogeny; Review; Species; Variation; Homology; Cortical hierarchies; Brain pathology; Limbic cortex; Phylogeny; Glia

The classical theory of cortical systematic variation has been independently described in reptiles, monotremes, marsupials and placental mammals, including primates, suggesting a common bauplan in the evolution of the cortex. The Structural Model is based on the systematic variation of the cortex an...