Abnormal static and dynamic functional network connectivity of the whole-brain in children with generalized tonic-clonic seizures

• Published in: Frontiers in neuroscience Vol. 17; p. 1236696
• Main Authors: Li, Yongxin, Ran, Yun, Chen, Qian
• Format: Journal Article
• Language: English
• Published: Lausanne Frontiers Research Foundation 21.08.2023; Frontiers Media S.A
• Subjects: Adults; Brain architecture; Brain mapping; Brain research; Children; Consciousness; Convulsions & seizures; dynamic functional connectivity; Epilepsy; Fainting; Firing pattern; Functional magnetic resonance imaging; Functional morphology; generalized tonic-clonic seizure children; independent component analysis; Magnetic resonance imaging; Medical imaging; Neural networks; Neuroimaging; Neuroscience; resting-state fMRI; Seizures; static functional connectivity

Generalized tonic-clonic seizures (GTCS) are a subtype of generalized seizures exhibiting bursts of bilaterally synchronous generalized spike-wave discharges. Numerous neuroimaging studies have reported aberrant functional activity and topological organization of brain network in epilepsy patients w...