Donor leukocyte infusions for multiple myeloma
Donor leukocyte infusion (DLI) has well-documented activity in CML, but the role of DLI in other diseases is less well defined. To evaluate the strategy in multiple myeloma (MM) we evaluated 25 MM patients from 15 centers who were treated with DLI. Patients with persistent or recurrent disease after...
Saved in:
Published in | Bone marrow transplantation (Basingstoke) Vol. 26; no. 11; pp. 1179 - 1184 |
---|---|
Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Basingstoke
Nature Publishing Group
01.12.2000
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Donor leukocyte infusion (DLI) has well-documented activity in CML, but the role of DLI in other diseases is less well defined. To evaluate the strategy in multiple myeloma (MM) we evaluated 25 MM patients from 15 centers who were treated with DLI. Patients with persistent or recurrent disease after allogeneic BMT received DLI from the original marrow donor (23 matched related, one mismatched family, and one matched unrelated). Chemotherapy was given before DLI in three patients. Two of 22 patients responded completely to DLI alone and three patients responded to the combination of DLI and chemotherapy. Nine patients who had not had sufficient disease control after DLI were given additional DLIs; five of these patients had either complete (two) or partial (three) responses. Thirteen of 25 evaluable patients developed acute GVHD and 11 of 21 evaluable patients developed chronic GVHD; all responders developed GVHD. No patients developed post-DLI pancytopenia. Four patients had responses which lasted >1 year after DLI, three patients had responses which lasted <1 year, and three patients had ongoing responses but with follow-up <1 year. In conclusion, DLI has anti-myeloma activity but the strategy is limited by no response or short duration of response in a significant percentage of patients and by significant GVHD in the majority of the responders. |
---|---|
AbstractList | Donor leukocyte infusion (dli) has well-documented activity in cml, but the role of dli in other diseases is less well defined. to evaluate the strategy in multiple myeloma (mm) we evaluated 25 mm patients from 15 centers who were treated with dli. patients with persistent or recurrent disease after allogeneic bmt received dli from the original marrow donor (23 matched related, one mismatched family, and one matched unrelated). chemotherapy was given before dli in three patients. two of 22 patients responded completely to dli alone and three patients responded to the combination of dli and chemotherapy. nine patients who had not had sufficient disease control after dli were given additional dlis; five of these patients had either complete (two) or partial (three) responses. thirteen of 25 evaluable patients developed acute gvhd and 11 of 21 evaluable patients developed chronic gvhd; all responders developed gvhd. no patients developed post-dli pancytopenia. four patients had responses which lasted >1 year after DLI, three patients had responses which lasted <1 year, and three patients had ongoing responses but with follow-up <1 year. In conclusion, DLI has anti-myeloma activity but the strategy is limited by no response or short duration of response in a significant percentage of patients and by significant GVHD in the majority of the responders. Bone Marrow Transplantation (2000) 26, 1179–1184. Donor leukocyte infusion (DLI) has well-documented activity in CML, but the role of DLI in other diseases is less well defined. To evaluate the strategy in multiple myeloma (MM) we evaluated 25 MM patients from 15 centers who were treated with DLI. Patients with persistent or recurrent disease after allogeneic BMT received DLI from the original marrow donor (23 matched related, one mismatched family, and one matched unrelated). Chemotherapy was given before DLI in three patients. Two of 22 patients responded completely to DLI alone and three patients responded to the combination of DLI and chemotherapy. Nine patients who had not had sufficient disease control after DLI were given additional DLIs; five of these patients had either complete (two) or partial (three) responses. Thirteen of 25 evaluable patients developed acute GVHD and 11 of 21 evaluable patients developed chronic GVHD; all responders developed GVHD. No patients developed post-DLI pancytopenia. Four patients had responses which lasted >1 year after DLI, three patients had responses which lasted <1 year, and three patients had ongoing responses but with follow-up <1 year. In conclusion, DLI has anti-myeloma activity but the strategy is limited by no response or short duration of response in a significant percentage of patients and by significant GVHD in the majority of the responders. Donor leukocyte infusion (DLI) has well-documented activity in CML, but the role of DLI in other diseases is less well defined. To evaluate the strategy in multiple myeloma (MM) we evaluated 25 MM patients from 15 centers who were treated with DLI. Patients with persistent or recurrent disease after allogeneic BMT received DLI from the original marrow donor (23 matched related, one mismatched family, and one matched unrelated). Chemotherapy was given before DLI in three patients. Two of 22 patients responded completely to DLI alone and three patients responded to the combination of DLI and chemotherapy. Nine patients who had not had sufficient disease control after DLI were given additional DLIs; five of these patients had either complete (two) or partial (three) responses. Thirteen of 25 evaluable patients developed acute GVHD and 11 of 21 evaluable patients developed chronic GVHD; all responders developed GVHD. No patients developed post-DLI pancytopenia. Four patients had responses which lasted >1 year after DLI, three patients had responses which lasted <1 year, and three patients had ongoing responses but with follow-up <1 year. In conclusion, DLI has anti-myeloma activity but the strategy is limited by no response or short duration of response in a significant percentage of patients and by significant GVHD in the majority of the responders. |
Author | HOROWITZ, M JOHNSON, M PORTER, D COLLINS, R. H DROBYSKI, W MARCELLUS, D NEVILL, T BARRETT, A. J LEVINE, J. E GIRALT, S KIRK, A SALAMA, M PARKER, P |
Author_xml | – sequence: 1 givenname: M surname: SALAMA fullname: SALAMA, M organization: University of Texas Southwestern Medical Center, Dallas, Texas, United States – sequence: 2 givenname: T surname: NEVILL fullname: NEVILL, T organization: Vancouver Hospital and Health Sciences Center, Vancouver, British Columbia, Canada – sequence: 3 givenname: A. J surname: BARRETT fullname: BARRETT, A. J organization: National Heart Lung and Blood Institute, Bethesda, Maryland, United States – sequence: 4 givenname: M surname: HOROWITZ fullname: HOROWITZ, M organization: International Bone Marrow Transplant Registry, Milwaukee, Wisconsin, United States – sequence: 5 givenname: R. H surname: COLLINS fullname: COLLINS, R. H organization: University of Texas Southwestern Medical Center, Dallas, Texas, United States – sequence: 6 givenname: D surname: MARCELLUS fullname: MARCELLUS, D organization: Johns Hopkins University Hospital, Baltimore, Maryland, United States – sequence: 7 givenname: P surname: PARKER fullname: PARKER, P organization: City of Hope, Duarte, California, United States – sequence: 8 givenname: M surname: JOHNSON fullname: JOHNSON, M organization: Baylor-Sammons Cancer Center, Dallas, Texas, United States – sequence: 9 givenname: A surname: KIRK fullname: KIRK, A organization: Baylor-Sammons Cancer Center, Dallas, Texas, United States – sequence: 10 givenname: D surname: PORTER fullname: PORTER, D organization: University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States – sequence: 11 givenname: S surname: GIRALT fullname: GIRALT, S organization: MD Anderson Cancer Center, Houston, Texas, United States – sequence: 12 givenname: J. E surname: LEVINE fullname: LEVINE, J. E organization: University of Michigan, Ann Arbor, Michigan, United States – sequence: 13 givenname: W surname: DROBYSKI fullname: DROBYSKI, W organization: Medical College of Wisconsin, Milwaukee, Wisconsin, United States |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=851977$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/11149728$$D View this record in MEDLINE/PubMed |
BookMark | eNqFkUtLxDAURoOMOA_dupSi4K4178dSxicMuNF1SJsUWttmbNrF_HszTFERxNWFy7kf3-UswazznQPgHMEMQSJvQp3l7ZAhATGX7AgsEBU8ZYSzGVjsdykhXM3BMoQaQkQpZCdgjhCiSmC5ANmd73yfNG5898VucEnVlWOofBeSMu7bsRmqbeOSduca35pTcFyaJrizaa7A28P96_op3bw8Pq9vN2lBBR1Sm1sopI01BOScOielRVIoknMCMXXGUFxibktJSmdQQZRlsIDY5kgIpwhZgetD7rb3H6MLg26rULimMZ3zY9ACM8QFV_-CMY9zCHkEr36BtR_7Lj6hMacYKSoZitTlnxTiXEHIaISyA1T0PoTelXrbV63pdxpBvbeiQ62jFT1ZiQcXU-qYt85-45OGH-VMKExT9qYrqvDFxWZKCPIJWjmUlA |
CODEN | BMTRE9 |
CitedBy_id | crossref_primary_10_1093_annonc_mdf638 crossref_primary_10_1053_bbmt_2003_50009 crossref_primary_10_18632_oncotarget_24637 crossref_primary_10_1586_14737140_6_12_1769 crossref_primary_10_3389_fonc_2017_00287 crossref_primary_10_3904_kjim_2009_24_4_287 crossref_primary_10_1053_bbmt_2003_50002 crossref_primary_10_1038_sj_bmt_1705667 crossref_primary_10_1111_j_1365_2257_2006_00773_x crossref_primary_10_1111_j_1600_0609_2010_01495_x crossref_primary_10_1182_bloodadvances_2017010686 crossref_primary_10_1038_bmt_2015_48 crossref_primary_10_1016_j_bbmt_2013_03_001 crossref_primary_10_1016_j_hoc_2014_08_010 crossref_primary_10_1016_j_jtct_2022_05_023 crossref_primary_10_1007_s12185_023_03602_1 crossref_primary_10_1038_bmt_2017_141 crossref_primary_10_1002_ajh_22273 crossref_primary_10_2165_00024669_200403010_00005 crossref_primary_10_1016_j_exphem_2012_09_008 crossref_primary_10_1038_sj_bmt_1705393 crossref_primary_10_1186_s12935_018_0553_8 crossref_primary_10_1038_sj_bmt_1703254 crossref_primary_10_1038_sj_bmt_1703652 crossref_primary_10_1038_sj_bmt_1703895 crossref_primary_10_1016_j_clim_2016_02_003 crossref_primary_10_1002_ajh_21744 crossref_primary_10_1016_j_jcyt_2013_11_001 crossref_primary_10_1016_j_bbmt_2017_05_006 crossref_primary_10_1038_sj_leu_2404775 crossref_primary_10_1182_blood_2004_05_2031 crossref_primary_10_1038_sj_leu_2403719 crossref_primary_10_1080_10428190210202 crossref_primary_10_1182_blood_2012_06_435040 crossref_primary_10_1182_blood_2009_08_238196 crossref_primary_10_1182_blood_2003_02_0342 crossref_primary_10_2217_fon_10_162 crossref_primary_10_1038_sj_bmt_1704670 crossref_primary_10_1002_ajh_22022 crossref_primary_10_1586_ehm_10_32 crossref_primary_10_1016_j_exphem_2013_08_003 crossref_primary_10_1038_bmt_2008_259 crossref_primary_10_1182_blood_2003_11_3862 crossref_primary_10_1038_sj_leu_2404641 crossref_primary_10_1038_sj_leu_2403432 crossref_primary_10_1038_sj_bmt_1704713 crossref_primary_10_1053_j_seminhematol_2005_09_005 crossref_primary_10_1586_17474086_2014_857270 crossref_primary_10_1097_00001622_200203000_00002 crossref_primary_10_1016_j_ejca_2005_11_038 crossref_primary_10_1038_sj_bmt_1704289 crossref_primary_10_1097_PAT_0b013e32834b6b24 crossref_primary_10_1177_2040620711412416 crossref_primary_10_6004_jnccn_2020_0057 crossref_primary_10_1007_BF02983779 crossref_primary_10_1016_j_intimp_2005_06_010 crossref_primary_10_1080_14712598_2017_1375095 crossref_primary_10_1155_2012_753407 crossref_primary_10_1016_j_critrevonc_2015_06_006 crossref_primary_10_1182_blood_2003_05_1513 crossref_primary_10_3390_jcm9072180 crossref_primary_10_1038_sj_bmt_1704531 crossref_primary_10_1016_j_beha_2006_10_002 crossref_primary_10_1182_blood_V99_12_4610 crossref_primary_10_1007_s11899_017_0365_2 crossref_primary_10_1016_j_bbmt_2015_08_025 crossref_primary_10_1016_S0753_3322_02_00175_0 crossref_primary_10_1053_beha_2001_0169 crossref_primary_10_1053_j_seminoncol_2003_10_019 crossref_primary_10_1038_bmt_2008_397 crossref_primary_10_1007_BF02982597 crossref_primary_10_1046_j_1468_0734_2002_00075_x crossref_primary_10_1111_j_1365_2141_2008_07340_x crossref_primary_10_1177_107327480200900205 crossref_primary_10_1182_blood_2007_03_082529 crossref_primary_10_1016_j_clml_2013_05_021 crossref_primary_10_1016_j_clml_2011_03_010 crossref_primary_10_3390_hemato2020012 crossref_primary_10_1038_sj_bmt_1705194 crossref_primary_10_1038_bmt_2017_183 crossref_primary_10_1007_s11899_008_0015_9 crossref_primary_10_1016_j_beha_2007_09_007 crossref_primary_10_1038_bmt_2010_90 crossref_primary_10_1200_JCO_2002_99_151 crossref_primary_10_1038_sj_bmt_1704667 crossref_primary_10_2217_imt_12_82 crossref_primary_10_1038_sj_leu_2404333 crossref_primary_10_1046_j_1365_2141_2001_03206_x crossref_primary_10_1007_s11899_013_0185_y crossref_primary_10_1097_00062752_200111000_00006 crossref_primary_10_1097_CCO_0b013e328358f619 crossref_primary_10_1097_MOH_0b013e32833e5b01 crossref_primary_10_1016_j_ctrv_2010_03_004 crossref_primary_10_1016_j_bbmt_2015_04_020 crossref_primary_10_1089_15258160152509082 crossref_primary_10_1007_s00277_002_0586_9 crossref_primary_10_1073_pnas_0530192100 crossref_primary_10_3109_10428194_2012_656635 crossref_primary_10_1038_leu_2014_189 crossref_primary_10_4049_jimmunol_175_2_1301 crossref_primary_10_1182_blood_2008_03_077974 crossref_primary_10_1182_blood_2002_09_2955 crossref_primary_10_1016_j_exphem_2009_03_008 crossref_primary_10_1016_j_beha_2008_07_001 crossref_primary_10_1038_sj_bmt_1704756 crossref_primary_10_1002_hon_673 crossref_primary_10_1016_j_clml_2014_07_012 crossref_primary_10_1016_S0037_1963_01_90016_2 crossref_primary_10_1016_j_bbmt_2010_08_001 crossref_primary_10_4049_jimmunol_0901797 crossref_primary_10_1038_bcj_2013_34 crossref_primary_10_1097_01_cco_0000208781_61452_d3 crossref_primary_10_1016_j_achaem_2015_03_005 crossref_primary_10_1016_j_bbmt_2018_04_018 crossref_primary_10_1016_j_clml_2020_01_010 crossref_primary_10_1016_j_bbmt_2005_11_520 crossref_primary_10_1158_1078_0432_CCR_12_3676 crossref_primary_10_2165_00003495_200363160_00001 crossref_primary_10_1182_asheducation_2001_1_157 crossref_primary_10_1016_j_ctrv_2010_08_008 crossref_primary_10_1038_sj_bmt_1705057 crossref_primary_10_1634_stemcells_2005_0492 crossref_primary_10_1034_j_1399_3046_2003_00016_x crossref_primary_10_1111_j_1365_2141_2005_05534_x crossref_primary_10_1002_hon_704 crossref_primary_10_1038_leu_2013_310 crossref_primary_10_1038_bmt_2013_54 crossref_primary_10_23736_S0031_0808_20_04142_7 crossref_primary_10_2217_imt_13_31 |
Cites_doi | 10.1182/blood.V84.10.3261.3261 10.1016/S0140-6736(05)64525-4 10.1200/JCO.1997.15.2.433 10.1182/blood.V86.5.2041.bloodjournal8652041 10.1056/NEJM198106183042507 10.1038/sj.bmt.1701236 10.1097/00007890-197410000-00001 10.1182/blood.V75.3.555.555 10.1200/JCO.1993.11.3.513 10.1182/blood.V90.10.4206 10.1182/blood.V83.11.3377.3377 10.1056/NEJM199401133300204 10.1182/blood.V87.6.2195.bloodjournal8762195 10.1182/blood.V84.4.1333.1333 10.1136/bmj.2.4993.626 10.1038/sj.leu.2400546 10.1016/0002-9343(80)90380-0 10.1182/blood.V82.8.2310.2310 10.1126/science.276.5319.1719 10.1182/blood.V86.11.4337.bloodjournal86114337 10.1016/S0140-6736(84)92009-9 10.1038/sj.bmt.1700934 10.1182/blood.V87.3.1196.bloodjournal8731196 10.1038/sj.bmt.1701459 10.1016/S0140-6736(96)90871-5 10.1182/blood.V76.12.2462.2462 |
ContentType | Journal Article |
Copyright | 2001 INIST-CNRS Copyright Nature Publishing Group Dec 2000 Macmillan Publishers Limited 2000. |
Copyright_xml | – notice: 2001 INIST-CNRS – notice: Copyright Nature Publishing Group Dec 2000 – notice: Macmillan Publishers Limited 2000. |
DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 3V. 7QO 7QP 7T5 7U9 7X7 7XB 88E 8AO 8FD 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ H94 HCIFZ K9. LK8 M0S M1P M7N M7P P64 PQEST PQQKQ PQUKI 7X8 |
DOI | 10.1038/sj.bmt.1702685 |
DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef ProQuest Central (Corporate) Biotechnology Research Abstracts Calcium & Calcified Tissue Abstracts Immunology Abstracts Virology and AIDS Abstracts ProQuest - Health & Medical Complete保健、医学与药学数据库 ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Technology Research Database ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central ProQuest Central Essentials Biological Science Collection ProQuest Central ProQuest Natural Science Collection ProQuest One Community College ProQuest Central Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection (Proquest) (PQ_SDU_P3) ProQuest Health & Medical Complete (Alumni) Biological Sciences Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Database Biotechnology and BioEngineering Abstracts ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef ProQuest Central Student Technology Research Database ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central Health Research Premium Collection Biotechnology Research Abstracts Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Algology Mycology and Protozoology Abstracts (Microbiology C) Biological Science Collection AIDS and Cancer Research Abstracts ProQuest Medical Library (Alumni) Virology and AIDS Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition Immunology Abstracts Engineering Research Database ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest Central (Alumni) MEDLINE - Academic |
DatabaseTitleList | ProQuest Central Student MEDLINE - Academic AIDS and Cancer Research Abstracts ProQuest Central Student MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1476-5365 |
EndPage | 1184 |
ExternalDocumentID | 998034251 10_1038_sj_bmt_1702685 11149728 851977 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GroupedDBID | --- -Q- .55 .XZ 0R~ 23N 2WC 36B 39C 3V. 4.4 406 53G 5GY 5RE 6J9 70F 7X7 88E 8AO 8FI 8FJ 8R4 8R5 AADWK AANZL AAPBV AATNV AAUGY AAWBL AAYFA AAYJO AAZLF ABAWZ ABDBF ABLJU ABPTK ABUWG ACBMV ACBRV ACBYP ACGFO ACGFS ACIGE ACIWK ACKTT ACMJI ACPRK ACRQY ACTTH ACVWB ADBBV ADFRT ADHDB ADMDM ADQMX ADYYL AEDAW AEFTE AEJRE AENEX AEVLU AEXYK AFFNX AFKRA AFNRJ AFRAH AFSHS AGAYW AGEZK AGGBP AGHAI AHMBA AHSBF AILAN AJCLW AJDOV AJRNO ALFFA ALMA_UNASSIGNED_HOLDINGS AMRJV AMYLF ASPBG AVWKF AXYYD AZFZN B0M BAWUL BBNVY BENPR BHPHI BKKNO BPHCQ BVXVI CCPQU CS3 DIK DNIVK DPUIP DU5 E3Z EAD EAP EBC EBD EBLON EBS EE. EIOEI EJD EMB EMK EMOBN EPL ESX EX3 F5P FDQFY FEDTE FERAY FIZPM FRP FSGXE FYUFA GX1 HCIFZ HZ~ IAO IH2 IHR IHW INH INR IQODW ITC IWAJR J5H JSO JZLTJ KQ8 M1P M7P N9A NAO NQJWS NXXTH NYICJ O9- OK1 OVD P2P PQQKQ PROAC PSQYO Q2X RNT RNTTT SNX SNYQT SOHCF SRMVM SV3 SWTZT TAOOD TBHMF TDRGL TEORI TR2 TSG TUS UDS UKHRP X7M ZA5 ZGI ZXP ~8M AACDK AASML ABAKF ABJNI ABZZP ACAOD ACZOJ AEFQL AEMSY AFBBN AGQEE AIGIU ALIPV CGR CUY CVF ECM EIF FIGPU HMCUK HVGLF LGEZI LOTEE NADUK NPM AAYXX CITATION 7QO 7QP 7T5 7U9 7XB 8FD 8FE 8FH 8FK AZQEC DWQXO FR3 GNUQQ H94 K9. LK8 M7N P64 PQEST PQUKI 7X8 |
ID | FETCH-LOGICAL-c474t-dbd078d53670664ee88d18793b63024eaa42f26df83fea1c39d50c02db177e933 |
IEDL.DBID | 7X7 |
ISSN | 0268-3369 |
IngestDate | Fri Aug 16 05:35:30 EDT 2024 Fri Aug 16 07:40:54 EDT 2024 Fri Sep 13 09:37:04 EDT 2024 Fri Sep 13 09:21:03 EDT 2024 Thu Sep 26 19:27:59 EDT 2024 Sat Sep 28 07:35:38 EDT 2024 Sun Oct 22 16:05:59 EDT 2023 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 11 |
Keywords | Blood product Human Immunopathology Transfusion Leukocyte Malignant hemopathy Myeloma Treatment Immunoglobulinopathy Donor Lymphoproliferative syndrome Immunotherapy Adoptive immunization |
Language | English |
License | CC BY 4.0 |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c474t-dbd078d53670664ee88d18793b63024eaa42f26df83fea1c39d50c02db177e933 |
Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
OpenAccessLink | https://doi.org/10.1038/sj.bmt.1702685 |
PMID | 11149728 |
PQID | 216690054 |
PQPubID | 36075 |
PageCount | 6 |
ParticipantIDs | proquest_miscellaneous_72516769 proquest_miscellaneous_17766006 proquest_journals_2642194851 proquest_journals_216690054 crossref_primary_10_1038_sj_bmt_1702685 pubmed_primary_11149728 pascalfrancis_primary_851977 |
PublicationCentury | 2000 |
PublicationDate | 2000-12-01 |
PublicationDateYYYYMMDD | 2000-12-01 |
PublicationDate_xml | – month: 12 year: 2000 text: 2000-12-01 day: 01 |
PublicationDecade | 2000 |
PublicationPlace | Basingstoke |
PublicationPlace_xml | – name: Basingstoke – name: England – name: London |
PublicationTitle | Bone marrow transplantation (Basingstoke) |
PublicationTitleAlternate | Bone Marrow Transplant |
PublicationYear | 2000 |
Publisher | Nature Publishing Group |
Publisher_xml | – name: Nature Publishing Group |
References | A Zomas (BF1702685_CR23) 1998; 21 R Gale (BF1702685_CR4) 1984; 2 F Van Rhee (BF1702685_CR10) 1994; 83 S Slavin (BF1702685_CR12) 1996; 87 H Glucksberg (BF1702685_CR25) 1974; 18 D Barnes (BF1702685_CR1) 1956; 2 H Bertz (BF1702685_CR20) 1997; 11 H Kolb (BF1702685_CR11) 1995; 86 W Drobyski (BF1702685_CR8) 1993; 82 R Truitt (BF1702685_CR2) 1995; 1 J Mehta (BF1702685_CR24) 1998; 22 C Bonini (BF1702685_CR28) 1997; 276 J Aschan (BF1702685_CR19) 1996; 348 M Horowitz (BF1702685_CR5) 1990; 75 B Bar (BF1702685_CR7) 1993; 11 D Porter (BF1702685_CR9) 1994; 330 G Tricot (BF1702685_CR17) 1996; 87 H Kolb (BF1702685_CR14) 1993; 30 G Tricot (BF1702685_CR18) 1997 EC Guinan (BF1702685_CR30) 1994; 84 B Glass (BF1702685_CR22) 1997; 20 S Giralt (BF1702685_CR29) 1995; 86 R Collins (BF1702685_CR13) 1997; 15 H Lokhorst (BF1702685_CR16) 1997; 90 H Shulman (BF1702685_CR26) 1980; 69 E Orsini (BF1702685_CR21) 1997; 90 P Tiberghien (BF1702685_CR27) 1994; 84 P Weiden (BF1702685_CR3) 1981; 304 H Kolb (BF1702685_CR6) 1990; 76 L Verdonck (BF1702685_CR15) 1996; 347 |
References_xml | – volume: 84 start-page: 3261 year: 1994 ident: BF1702685_CR30 publication-title: Blood doi: 10.1182/blood.V84.10.3261.3261 contributor: fullname: EC Guinan – volume: 348 start-page: 346 year: 1996 ident: BF1702685_CR19 publication-title: Lancet doi: 10.1016/S0140-6736(05)64525-4 contributor: fullname: J Aschan – volume: 90 start-page: 549a (Abstr. 24 year: 1997 ident: BF1702685_CR21 publication-title: Blood contributor: fullname: E Orsini – volume: 15 start-page: 433 year: 1997 ident: BF1702685_CR13 publication-title: J Clin Oncol doi: 10.1200/JCO.1997.15.2.433 contributor: fullname: R Collins – volume: 86 start-page: 2041 year: 1995 ident: BF1702685_CR11 publication-title: Blood doi: 10.1182/blood.V86.5.2041.bloodjournal8652041 contributor: fullname: H Kolb – volume: 304 start-page: 1529 year: 1981 ident: BF1702685_CR3 publication-title: New Engl J Med doi: 10.1056/NEJM198106183042507 contributor: fullname: P Weiden – volume: 21 start-page: 1163 year: 1998 ident: BF1702685_CR23 publication-title: Bone Marrow Transplant doi: 10.1038/sj.bmt.1701236 contributor: fullname: A Zomas – volume: 18 start-page: 295 year: 1974 ident: BF1702685_CR25 publication-title: Transplantation doi: 10.1097/00007890-197410000-00001 contributor: fullname: H Glucksberg – start-page: pp. 225 volume-title: Autologous Marrow and Blood Transplantation: Proceedings of the Eighth International Symposium, Arlington, Texas year: 1997 ident: BF1702685_CR18 contributor: fullname: G Tricot – volume: 75 start-page: 555 year: 1990 ident: BF1702685_CR5 publication-title: Blood doi: 10.1182/blood.V75.3.555.555 contributor: fullname: M Horowitz – volume: 11 start-page: 513 year: 1993 ident: BF1702685_CR7 publication-title: J Clin Oncol doi: 10.1200/JCO.1993.11.3.513 contributor: fullname: B Bar – volume: 90 start-page: 4206 year: 1997 ident: BF1702685_CR16 publication-title: Blood doi: 10.1182/blood.V90.10.4206 contributor: fullname: H Lokhorst – volume: 83 start-page: 3377 year: 1994 ident: BF1702685_CR10 publication-title: Blood doi: 10.1182/blood.V83.11.3377.3377 contributor: fullname: F Van Rhee – volume: 330 start-page: 100 year: 1994 ident: BF1702685_CR9 publication-title: New Engl J Med doi: 10.1056/NEJM199401133300204 contributor: fullname: D Porter – volume: 87 start-page: 2195 year: 1996 ident: BF1702685_CR12 publication-title: Blood doi: 10.1182/blood.V87.6.2195.bloodjournal8762195 contributor: fullname: S Slavin – volume: 84 start-page: 1333 year: 1994 ident: BF1702685_CR27 publication-title: Blood doi: 10.1182/blood.V84.4.1333.1333 contributor: fullname: P Tiberghien – volume: 2 start-page: 626 year: 1956 ident: BF1702685_CR1 publication-title: Br Med J doi: 10.1136/bmj.2.4993.626 contributor: fullname: D Barnes – volume: 30 start-page: 37 year: 1993 ident: BF1702685_CR14 publication-title: Semin Hematol contributor: fullname: H Kolb – volume: 11 start-page: 281 year: 1997 ident: BF1702685_CR20 publication-title: Leukemia doi: 10.1038/sj.leu.2400546 contributor: fullname: H Bertz – volume: 69 start-page: 204 year: 1980 ident: BF1702685_CR26 publication-title: Am J Med doi: 10.1016/0002-9343(80)90380-0 contributor: fullname: H Shulman – volume: 1 start-page: 61 year: 1995 ident: BF1702685_CR2 publication-title: Bone Marrow Transplant contributor: fullname: R Truitt – volume: 82 start-page: 2310 year: 1993 ident: BF1702685_CR8 publication-title: Blood doi: 10.1182/blood.V82.8.2310.2310 contributor: fullname: W Drobyski – volume: 276 start-page: 1719 year: 1997 ident: BF1702685_CR28 publication-title: Science doi: 10.1126/science.276.5319.1719 contributor: fullname: C Bonini – volume: 86 start-page: 4337 year: 1995 ident: BF1702685_CR29 publication-title: Blood doi: 10.1182/blood.V86.11.4337.bloodjournal86114337 contributor: fullname: S Giralt – volume: 2 start-page: 28 year: 1984 ident: BF1702685_CR4 publication-title: Lancet doi: 10.1016/S0140-6736(84)92009-9 contributor: fullname: R Gale – volume: 20 start-page: 533 year: 1997 ident: BF1702685_CR22 publication-title: Bone Marrow Transplant doi: 10.1038/sj.bmt.1700934 contributor: fullname: B Glass – volume: 87 start-page: 1196 year: 1996 ident: BF1702685_CR17 publication-title: Blood doi: 10.1182/blood.V87.3.1196.bloodjournal8731196 contributor: fullname: G Tricot – volume: 22 start-page: 835 year: 1998 ident: BF1702685_CR24 publication-title: Bone Marrow Transplant doi: 10.1038/sj.bmt.1701459 contributor: fullname: J Mehta – volume: 347 start-page: 800 year: 1996 ident: BF1702685_CR15 publication-title: Lancet doi: 10.1016/S0140-6736(96)90871-5 contributor: fullname: L Verdonck – volume: 76 start-page: 2462 year: 1990 ident: BF1702685_CR6 publication-title: Blood doi: 10.1182/blood.V76.12.2462.2462 contributor: fullname: H Kolb |
SSID | ssj0014405 |
Score | 2.088459 |
Snippet | Donor leukocyte infusion (DLI) has well-documented activity in CML, but the role of DLI in other diseases is less well defined. To evaluate the strategy in... Donor leukocyte infusion (dli) has well-documented activity in cml, but the role of dli in other diseases is less well defined. to evaluate the strategy in... |
SourceID | proquest crossref pubmed pascalfrancis |
SourceType | Aggregation Database Index Database |
StartPage | 1179 |
SubjectTerms | Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Bone marrow Bone marrow transplantation Bone Marrow Transplantation - immunology Chemotherapy Combined Modality Therapy Disease control Female Graft vs Host Disease - immunology Graft-versus-host reaction Humans Immunotherapy, Adoptive Leukocyte Transfusion - adverse effects Leukocytes Living Donors Male Medical sciences Middle Aged Multiple myeloma Multiple Myeloma - drug therapy Multiple Myeloma - immunology Multiple Myeloma - therapy Pancytopenia Prospective Studies Retrospective Studies Stem cell transplantation Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation |
Title | Donor leukocyte infusions for multiple myeloma |
URI | https://www.ncbi.nlm.nih.gov/pubmed/11149728 https://www.proquest.com/docview/216690054/abstract/ https://www.proquest.com/docview/2642194851/abstract/ https://search.proquest.com/docview/17766006 https://search.proquest.com/docview/72516769 |
Volume | 26 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1JT9tAFH5ikRBShShLa6CpD5U4mcSe8Yx9qlqWRkigCoGUmzWbDzSxQ-wc-Pe85yUVQnCesWx_8-z3vR3gh45HoeahDiSyETRQJAuUTlVguOERdSzimmqHb27F-IFfT-LJGvzpa2EorbL_JzY_alsa8pEPo1CgIYcEY6g0OQFMPfw5fwpofBSFWbtZGuuwGUbIKlCw5WRleVEAM26dLUnAmEj77o0sGVaPZ3pGo3lpMX6lnT7NVYVA5e2Ei_cpaKOKrnZhp-OQ_q_20D_Dmiv2YOumi5Lvw9lFWZQLf-qW_0rzXDsfpWhJXrHKR4rq9zmE_uzZTcuZOoCHq8v783HQzUVABCWvA6stKnYbU-81IbhzSWJpaDjTgqHKdUrxKI-EzROWOxUaltp4ZEaRpVZTLmXsEDaKsnBfwTdWstC53FjNuYtitF7SUc64yZGZMMc9OO3xyOZt-4usCVuzJKseM0Qu65Dz4OQVXKvtCZXGSg-Oe_Sy7iupstWZ0sVvV6kGl5rXhB58Xy2j9FNIQxWuXFZ4cymQson3d0gkcJTG68GX9sz-vweagqmMkqMPH-0Ytpvq-yaD5QQ26sXSfUMeUutBI2MD2Px9efv37gVoRd0D |
link.rule.ids | 315,786,790,12083,21416,27957,27958,31754,31755,33779,33780,43345,43840,74102,74659 |
linkProvider | ProQuest |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3JTsMwEB1BkQAJIXbCmgMSp0ATO3ZyQgioylJOIPUWxUsOQJNC2gN_z0yWIoTgbEdO3jieN54N4ESFXV9xX3kS2QgaKJJ5qYpTT3PNA6pYxBXlDg8eRf-Z3w3DYRObUzZhle2ZWB3UptB0R34e-AINOSQYF-N3j5pGkXO16aAxDwucMU4RfXI4s7fIbRnWVyyRx5iI25qNLDovX87UiBry0mD4QyetjNMS4cnqvhZ_E89KAfXWYLVhju5lLep1mLP5BiwOGt_4JpxdF3nx4b7Z6WuhPyfWxb0zpbuw0kVi6raRg-7o074Vo3QLnns3T1d9r-mGgLhJPvGMMqjOTUgV14Tg1kaRoVbhTAmGitamKQ-yQJgsYplNfc1iE3Z1NzBUYMrGjG1DJy9yuwuuNpL51mbaKM5tEKLNEnczxnWGfIRZ7sBpi0cyroteJJWzmkVJ-ZIgckmDnAMHP-CaTY8oIVY6sN-ilzT_RpnMJEkP_x6lzFsqWeM7cDwbxj1Pjow0t8W0xMWlQKIm_p4hkbZR8K4DO7XMvr8DDcBYBtHev692DEv9p8FD8nD7eL8Py1X-fRXDcgCdycfUHiITmaijar99AUjO2pw |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT9tAEB4VIiGkCvUB1JA2PiD1ZBJ717v2CdFClEKJEAKJm-V9-ADEDjg58O-ZsddBqKLnXcv2t7M73-y8AA5UPAoVD1UgkY2ggSJZkKs0DzTXPKKKRVxR7vDFVExu-NltfOtKCtUurLI7E5uD2lSa7siHUSjQkEOCMSxcVMTlyfho_hhQAylytLpuGmvQk1zEKOC9X6fTy6uVS4HzNp4xEknAmEi7Co4sGdZ3h2pG7XlpMH6joT7O8xrBKtouF-_T0EYdjT_BluOR_nG78J_hgy2_wMaF85R_hcOTqqye_Ae7vK_088L6KElLuhmrfaSpfhdH6M-e7UM1y7fhZnx6_XsSuN4IiKLki8Aog8rdxFR_TQhubZIYahzOlGCodm2e86iIhCkSVtg81Cw18UiPIkPlpmzK2A6sl1Vpv4GvjWShtYU2inMbxWjBpKOCcV0gO2GWe_CzwyObtyUwssZ1zZKsvssQucwh50H_DVyr6Qmlx0oP9jv0MrdT6my1rvTwv6OUh0sFbEIPBqth3AHk1shLWy1rfLkUSNvE-zMkkjgK5fVgt12z1_9AczCVUbL3308bwAYKW_b3z_R8HzabZPwmoKUP64unpf2OtGShfjiBewFW1uA_ |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Donor+leukocyte+infusions+for+multiple+myeloma&rft.jtitle=Bone+marrow+transplantation+%28Basingstoke%29&rft.au=Salama%2C+M&rft.au=Nevill%2C+T&rft.au=Marcellus%2C+D&rft.au=Parker%2C+P&rft.date=2000-12-01&rft.pub=Nature+Publishing+Group&rft.issn=0268-3369&rft.eissn=1476-5365&rft.volume=26&rft.issue=11&rft.spage=1179&rft_id=info:doi/10.1038%2Fsj.bmt.1702685&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=998034251 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0268-3369&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0268-3369&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0268-3369&client=summon |