Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury
High mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that is present in almost all cells and regulates the activity of innate immune responses in both intracellular and extracellular settings. Current evidence suggests that HMGB1 plays a pivotal role in human pathological and pathophysi...
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Published in | Acta pharmacologica Sinica Vol. 43; no. 3; pp. 520 - 528 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Singapore
Springer Singapore
01.03.2022
Nature Publishing Group |
Subjects | |
Online Access | Get full text |
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