Hyperosmolar blood–brain barrier opening using intra-arterial injection of hyperosmotic mannitol in mice under real-time MRI guidance - Chu, Chengyan; Jablonska, Anna; Gao, Yue; Lan, Xiaoyan; Lesniak, Wojciech G.; Liang, Yajie; Liu, Guanshu; Li, Shen; Magnus, Tim; Pearl, Monica; Janowski, Miroslaw; Walczak, Piotr (Nature protocols, 2022)
Keywords: 631/154/152; 631/1647/245/1628; 631/1647/334/1874/345; 631/378/1341; 692/617; Analytical Chemistry; Animals; Biological Techniques; Biomedical and Life Sciences; Blood-brain barrier; Blood-Brain Barrier - diagnostic imaging; Blood-Brain Barrier - drug effects; Brain damage; Capillary Permeability - drug effects; Carotid arteries; Cerebral blood flow; Chemical compounds; Computational Biology/Bioinformatics; Drug dosages; Injection; Injections, Intra-Arterial; Ischemia; Life Sciences; Magnetic Resonance Imaging; Male; Mannitol; Mannitol - administration & dosage; Mannitol - pharmacology; Medical research; Mice; Mice, SCID; Microarrays; Neurological diseases; Occlusion; Organic Chemistry; Osmotic Pressure; Pharmacology; Protocol; Radiology; Reproducibility; Variability; Veins & arteries