Increased platelet activation in sleep apnea subjects with intermittent hypoxemia

• Published in: Sleep & breathing Vol. 24; no. 4; pp. 1537 - 1547
• Main Authors: Krieger, Ana C., Anand, Ranjini, Hernandez-Rosa, Evelyn, Maidman, Allison, Milrad, Sara, DeGrazia, Miles Q., Choi, Alexander J., Oromendia, Clara, Marcus, Aaron J., Drosopoulos, Joan H. F.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.12.2020; Springer Nature B.V
• Subjects: Agonists; Apnea; Cardiovascular disease; Cardiovascular diseases; CD40L protein; Collagen; Dentistry; Epinephrine; Flow cytometry; Hypoxemia; Internal Medicine; Medicine; Medicine & Public Health; Monocytes; Neurology; Otorhinolaryngology; P-selectin; Pediatrics; Platelet aggregation; Pneumology/Respiratory System; Sleep; Sleep apnea; Sleep Breathing Physiology and Disorders • Original Article; Sleep disorders; Surface markers; Thrombin; Thrombosis; Intermittent hypoxemia; Cardiovascular disease; Stroke; Platelet aggregation; Platelet activation; Obstructive sleep apnea

Purpose Obstructive sleep apnea (OSA) is independently associated with increased risk for stroke and other cardiovascular diseases. Since activated platelets play an important role in cardiovascular disease, the objective of this study was to determine whether platelet reactivity was altered in OSA...