Two Binding Sites for [3H]PBR28 in Human Brain: Implications for TSPO PET Imaging of Neuroinflammation - Owen, David R; Howell, Owain W; Tang, Sac-Pham; Wells, Lisa A; Bennacef, Idriss; Bergstrom, Mats; Gunn, Roger N; Rabiner, Eugenii A; Wilkins, Martin R; Reynolds, Richard; Matthews, Paul M; Parker, Christine A (Journal of cerebral blood flow and metabolism, 2010)
Keywords: Acetamides - metabolism; Adult; Aged; Aged, 80 and over; Autoradiography; Binding Sites; Binding, Competitive - drug effects; Biological and medical sciences; Brain - diagnostic imaging; Brain Chemistry; Carbon Radioisotopes; Female; Humans; Immunohistochemistry; Investigative techniques, diagnostic techniques (general aspects); Isoquinolines; Male; Medical sciences; Membranes - diagnostic imaging; Membranes - metabolism; Middle Aged; Nerve Tissue Proteins - analysis; Nerve Tissue Proteins - metabolism; Nervous system; Neuritis - diagnostic imaging; Neurology; Original; Positron-Emission Tomography; Pyridines - metabolism; Radioligand Assay; Receptors, GABA - metabolism; Tissue Banks; Ultrasonic investigative techniques; Vascular diseases and vascular malformations of the nervous system; [3H]PBR28; PBR; radioligand binding; TSPO; [3H]PK11195; Human; Nervous system diseases; H]PBR28; Cerebral disorder; Encephalon; Central nervous system disease; H]PK11195; [; Positron emission tomography; Cerebrovascular disease