Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation - Zhang, Yunjia; Jiang, Hong; Dong, Mengdie; Min, Jiao; He, Xian; Tan, Yongkang; Liu, Fuhao; Chen, Minghong; Chen, Xiang; Yin, Quanwen; Zheng, Longbin; Shao, Yongfeng; et al. (Cell reports (Cambridge), 2024)
Keywords: Animals; atherosclerosis; Atherosclerosis - genetics; Atherosclerosis - metabolism; Atherosclerosis - pathology; CP: Molecular biology; histone lactylation; Histones - metabolism; Humans; inflammatory; Lysine - metabolism; macrophage; Macrophage Activation; Macrophages - metabolism; MCT4; Mice; Mice, Inbred C57BL; Monocarboxylic Acid Transporters - genetics; Monocarboxylic Acid Transporters - metabolism; Muscle Proteins - genetics; Muscle Proteins - metabolism; tissue repair; atherosclerosis; MCT4; histone lactylation; inflammatory; CP: Molecular biology; macrophage; tissue repair