Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes
The vast potential of human induced pluripotent stem-cell-derived cardiomyocytes (hiPSC-CMs) in preclinical models of cardiac pathologies, precision medicine, and drug screening remains to be fully realized because hiPSC-CMs are immature without adult-like characteristics. Here, we present a method...
Saved in:
Published in | Cell reports (Cambridge) Vol. 40; no. 4; p. 111146 |
---|---|
Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
26.07.2022
Elsevier |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The vast potential of human induced pluripotent stem-cell-derived cardiomyocytes (hiPSC-CMs) in preclinical models of cardiac pathologies, precision medicine, and drug screening remains to be fully realized because hiPSC-CMs are immature without adult-like characteristics. Here, we present a method to accelerate hiPSC-CM maturation on a substrate, cardiac mimetic matrix (CMM), mimicking adult human heart matrix ligand chemistry, rigidity, and submicron ultrastructure, which synergistically mature hiPSC-CMs rapidly within 30 days. hiPSC-CMs matured on CMM exhibit systemic transcriptomic maturation toward an adult heart state, are aligned with high strain energy, metabolically rely on oxidative phosphorylation and fatty acid oxidation, and display enhanced redox handling capability, efficient calcium handling, and electrophysiological features of ventricular myocytes. Endothelin-1-induced pathological hypertrophy is mitigated on CMM, highlighting the role of a native cardiac microenvironment in withstanding hypertrophy progression. CMM is a convenient model for accelerated development of ventricular myocytes manifesting highly specialized cardiac-specific functions.
[Display omitted]
•Rapid iPSC-CM maturation on surfaces mimicking native cardiac microenvironment•Concurrent metabolic and redox maturation on cardiac mimetic matrix (CMM)•Hybrid Steiner tree network identifies intermediaries involved in cardiac maturation•Cardiac ultrastructure moderates hypertrophic disease phenotype
Afzal et al. induce physiologically inspired cardiac maturation. The resulting cardiac constructs display features of ventricular myocytes within 30 days including structural alignment, electrophysiological maturation, molecular signature, mitochondrial energetics and fatty acid oxidation, and efficient oxidative stress handling capability, facilitating their use in disease modeling and preclinical drug screening. |
---|---|
AbstractList | The vast potential of human induced pluripotent stem-cell-derived cardiomyocytes (hiPSC-CMs) in preclinical models of cardiac pathologies, precision medicine, and drug screening remains to be fully realized because hiPSC-CMs are immature without adult-like characteristics. Here, we present a method to accelerate hiPSC-CM maturation on a substrate, cardiac mimetic matrix (CMM), mimicking adult human heart matrix ligand chemistry, rigidity, and submicron ultrastructure, which synergistically mature hiPSC-CMs rapidly within 30 days. hiPSC-CMs matured on CMM exhibit systemic transcriptomic maturation toward an adult heart state, are aligned with high strain energy, metabolically rely on oxidative phosphorylation and fatty acid oxidation, and display enhanced redox handling capability, efficient calcium handling, and electrophysiological features of ventricular myocytes. Endothelin-1-induced pathological hypertrophy is mitigated on CMM, highlighting the role of a native cardiac microenvironment in withstanding hypertrophy progression. CMM is a convenient model for accelerated development of ventricular myocytes manifesting highly specialized cardiac-specific functions. The vast potential of human induced pluripotent stem-cell-derived cardiomyocytes (hiPSC-CMs) in preclinical models of cardiac pathologies, precision medicine, and drug screening remains to be fully realized because hiPSC-CMs are immature without adult-like characteristics. Here, we present a method to accelerate hiPSC-CM maturation on a substrate, cardiac mimetic matrix (CMM), mimicking adult human heart matrix ligand chemistry, rigidity, and submicron ultrastructure, which synergistically mature hiPSC-CMs rapidly within 30 days. hiPSC-CMs matured on CMM exhibit systemic transcriptomic maturation toward an adult heart state, are aligned with high strain energy, metabolically rely on oxidative phosphorylation and fatty acid oxidation, and display enhanced redox handling capability, efficient calcium handling, and electrophysiological features of ventricular myocytes. Endothelin-1-induced pathological hypertrophy is mitigated on CMM, highlighting the role of a native cardiac microenvironment in withstanding hypertrophy progression. CMM is a convenient model for accelerated development of ventricular myocytes manifesting highly specialized cardiac-specific functions. [Display omitted] •Rapid iPSC-CM maturation on surfaces mimicking native cardiac microenvironment•Concurrent metabolic and redox maturation on cardiac mimetic matrix (CMM)•Hybrid Steiner tree network identifies intermediaries involved in cardiac maturation•Cardiac ultrastructure moderates hypertrophic disease phenotype Afzal et al. induce physiologically inspired cardiac maturation. The resulting cardiac constructs display features of ventricular myocytes within 30 days including structural alignment, electrophysiological maturation, molecular signature, mitochondrial energetics and fatty acid oxidation, and efficient oxidative stress handling capability, facilitating their use in disease modeling and preclinical drug screening. |
ArticleNumber | 111146 |
Author | Nikolaus, Joerg Yue, Lixia Yankova, Maya Kshitiz Afzal, Junaid Feng, Jianlin Ajeti, Visar Liu, Yamin Sayyad, Wasim A. Du, Wenqiang Zong, Pengyu Suhail, Yasir Deymier, Alix C. |
Author_xml | – sequence: 1 givenname: Junaid orcidid: 0000-0002-2877-234X surname: Afzal fullname: Afzal, Junaid email: junaid.afzal@ucsf.edu organization: Department of Medicine, Division of Cardiology, University of California, San Francisco, San Francisco, CA 94158, USA – sequence: 2 givenname: Yamin orcidid: 0000-0003-0031-7799 surname: Liu fullname: Liu, Yamin organization: Department of Biomedical Engineering, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 3 givenname: Wenqiang orcidid: 0000-0003-2605-4325 surname: Du fullname: Du, Wenqiang organization: Department of Biomedical Engineering, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 4 givenname: Yasir surname: Suhail fullname: Suhail, Yasir organization: Department of Biomedical Engineering, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 5 givenname: Pengyu surname: Zong fullname: Zong, Pengyu organization: Department of Cell Biology, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 6 givenname: Jianlin surname: Feng fullname: Feng, Jianlin organization: Department of Cell Biology, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 7 givenname: Visar surname: Ajeti fullname: Ajeti, Visar organization: Department of Biomedical Engineering, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 8 givenname: Wasim A. orcidid: 0000-0002-6064-2860 surname: Sayyad fullname: Sayyad, Wasim A. organization: Department of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06510, USA – sequence: 9 givenname: Joerg surname: Nikolaus fullname: Nikolaus, Joerg organization: West Campus Imaging Core, Yale University, New Haven, CT 06477, USA – sequence: 10 givenname: Maya surname: Yankova fullname: Yankova, Maya organization: Electron Microscopy Core, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 11 givenname: Alix C. surname: Deymier fullname: Deymier, Alix C. organization: Department of Biomedical Engineering, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 12 givenname: Lixia surname: Yue fullname: Yue, Lixia organization: Department of Cell Biology, University of Connecticut Health, Farmington, CT 06032, USA – sequence: 13 surname: Kshitiz fullname: Kshitiz email: kshitiz@uchc.edu organization: Department of Biomedical Engineering, University of Connecticut Health, Farmington, CT 06032, USA |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35905711$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kU9v1DAQxS1UREvpN0AoRy672I7j9V6Q0Io_lSpxgbM1GY_BqyRebKdir3xyHFIqTszFntF782T_nrOLKU7E2EvBt4IL_ea4RRoSnbaSS7kVtZR-wq6kFGIjpNpd_HO_ZDc5H3ktzYXYq2fssu32vNsJccV-HSC5ANjMQ0mQS5qxzImaMOVTSOSaEUoKP2vvZqTcgLuHCZc5FejjELCByTV-nrCEOMGwGOYES9NE37jgPSWaSoBSXd_nEaYGl8w4niOeC-UX7KmHIdPNw3nNvn54_-XwaXP3-ePt4d3dBtVOlQ0aRb5v0XPuPLquM7wFQsKOk3NecyNNq4m06NEY44j4nhvX9yCVU7u2vWa3614X4WhPKYyQzjZCsH8GMX2zkErAgSx3vecAeyFkqxA7AN0b3YIy2kjpVd31et11SvHHTLnYMeSKZICJ4pyt1HttdHXLKlWrFFPMOZF_jBbcLjDt0a4w7QLTrjCr7dVDwtyP5B5Nf9FVwdtVQPXP7gMlmzHQwqZyw1IfFf6f8BsH2Leo |
CitedBy_id | crossref_primary_10_3390_metabo13040549 crossref_primary_10_1016_j_molliq_2023_122668 crossref_primary_10_3390_ijms24098420 crossref_primary_10_1242_dev_201103 crossref_primary_10_3389_fcell_2022_927631 crossref_primary_10_1002_agt2_614 crossref_primary_10_1016_j_cels_2022_11_003 crossref_primary_10_1186_s13287_023_03470_w crossref_primary_10_1002_adma_202403642 crossref_primary_10_1021_acsami_3c18919 crossref_primary_10_1007_s12551_023_01099_w crossref_primary_10_3389_fbioe_2023_1155052 |
Cites_doi | 10.1016/j.cels.2018.06.003 10.1016/j.stem.2016.02.011 10.1002/adfm.201910660 10.1016/j.jacbts.2019.03.004 10.1002/dvdy.24455 10.1161/CIRCRESAHA.118.313472 10.1634/stemcells.2006-0466 10.1161/CIRCRESAHA.117.310738 10.1016/j.bbrc.2018.03.198 10.1073/pnas.1409525111 10.1161/01.HYP.0000047668.48494.39 10.1038/nprot.2014.018 10.1038/srep03887 10.3389/fbioe.2020.567842 10.1039/C7CC01988B 10.1016/j.celrep.2015.10.032 10.1093/cvr/cvr071 10.1039/c2ib20067h 10.1016/j.cellsig.2017.04.010 10.1073/pnas.0506580102 10.1038/415198a 10.1016/j.biomaterials.2020.120060 10.1016/j.actbio.2015.08.017 10.1161/CIRCULATIONAHA.114.014998 10.1161/CIRCRESAHA.117.305365 10.1007/978-3-319-59776-8_22 10.1038/nmeth.1212 10.1016/j.freeradbiomed.2013.04.001 10.1016/S0021-9258(18)54623-8 10.1038/s41586-018-0016-3 10.1093/nar/gkx1064 10.1093/nar/gkj109 10.1038/sdata.2015.63 10.1152/ajpcell.00060.2009 10.1038/s41586-018-0762-2 10.1126/scisignal.2003417 10.1242/dev.024166 10.3389/fcell.2020.621644 10.1161/CIRCRESAHA.114.300558 10.1038/s41598-017-08713-4 10.1016/0022-2828(92)93381-S 10.1021/acsami.5b11671 10.1172/JCI8040 10.1161/CIRCRESAHA.111.255216 10.1089/ten.tea.2013.0008 10.1529/biophysj.107.113670 10.1038/s41592-018-0188-7 10.1097/FJC.0b013e3181e74a14 10.1161/CIRCRESAHA.118.313249 10.3389/fcell.2020.00178 10.1098/rstb.2018.0215 10.1007/BF01581256 10.1007/978-1-4939-7493-1_2 10.1016/j.celrep.2020.107925 10.1016/j.freeradbiomed.2011.01.003 10.1016/j.devcel.2011.08.008 10.1016/j.tiv.2020.104891 10.1016/j.celrep.2016.12.040 10.1097/00004872-199816070-00018 10.1016/S0076-6879(98)98041-7 10.1371/journal.pone.0126338 10.1089/ars.2009.2948 10.1089/scd.2012.0490 10.1038/nprot.2012.127 10.1016/j.neuron.2012.06.040 10.1016/j.cmet.2007.11.006 10.1161/CIRCRESAHA.115.307580 10.1161/CIRCRESAHA.119.315862 10.1002/stem.1700 10.1152/physrev.00006.2004 10.1093/nar/gku1113 10.2217/nnm.12.204 10.1038/nrm.2017.108 10.3389/fphar.2014.00196 10.1126/scisignal.2003002 10.12688/f1000research.24956.2 10.3233/THC-1997-51-209 10.1093/cvr/cvn301 10.1161/CIRCRESAHA.117.311059 10.1161/RES.0000000000000291 10.1038/nmeth.2999 10.1161/CIRCULATIONAHA.119.045115 10.1016/j.biomaterials.2012.03.021 10.1146/annurev-cellbio-092910-154237 10.1113/jphysiol.2011.212712 10.1038/s41467-017-01946-x 10.1016/j.stem.2012.09.013 10.1161/CIRCRESAHA.113.300376 10.1111/jcmm.14122 10.1161/CIRCRESAHA.116.302752 10.1093/nar/gkh036 10.1242/dev.067454 10.1038/srep18705 10.1016/j.addr.2015.12.023 10.1186/scrt406 10.1016/j.stem.2018.09.009 10.1039/C8BM01348A 10.1016/j.bbamcr.2015.11.005 10.1152/physrev.00015.2009 10.1161/CIRCGENETICS.115.001264 10.1155/2018/5835072 10.1038/nature12354 10.1073/pnas.1107332108 10.1016/j.jacbts.2017.03.016 10.1021/acsbiomaterials.8b01112 10.1016/j.pharmthera.2017.10.001 10.1177/0963689718779346 |
ContentType | Journal Article |
Copyright | 2022 The Author(s) Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved. |
Copyright_xml | – notice: 2022 The Author(s) – notice: Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved. |
DBID | 6I. AAFTH CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 DOA |
DOI | 10.1016/j.celrep.2022.111146 |
DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic DOAJ Directory of Open Access Journals |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE |
Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Biology |
EISSN | 2211-1247 |
EndPage | 111146 |
ExternalDocumentID | oai_doaj_org_article_0dbf0aa911234cc5aa6b863a486822f4 10_1016_j_celrep_2022_111146 35905711 S221112472200955X |
Genre | Research Support, U.S. Gov't, Non-P.H.S Research Support, Non-U.S. Gov't Journal Article |
GrantInformation_xml | – fundername: NHLBI NIH HHS grantid: R01 HL147350 |
GroupedDBID | 0R~ 0SF 4.4 457 53G 5VS 6I. AACTN AAEDT AAEDW AAFTH AAIKJ AAKRW AALRI AAUCE AAXUO ABMAC ABMWF ACGFO ACGFS ADBBV ADEZE AENEX AEXQZ AFTJW AGHFR AITUG ALKID ALMA_UNASSIGNED_HOLDINGS AMRAJ BAWUL BCNDV DIK EBS EJD FCP FDB FRP GROUPED_DOAJ GX1 IXB KQ8 M41 M48 NCXOZ O-L O9- OK1 RCE ROL SSZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX ADVLN CITATION HZ~ IPNFZ RIG 7X8 |
ID | FETCH-LOGICAL-c474t-c84efb3cf00dfcd55803aecec50eddf6082836ee61bc888dee0908dbba24d4733 |
IEDL.DBID | M48 |
ISSN | 2211-1247 |
IngestDate | Fri Jul 05 11:49:45 EDT 2024 Thu Jul 25 17:01:56 EDT 2024 Fri Aug 23 00:29:13 EDT 2024 Thu May 23 23:30:13 EDT 2024 Tue Jul 25 20:57:15 EDT 2023 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 4 |
Keywords | metabolic maturation pathological hypertrophy redox handling cardiac mimetic CP: cell biology substrate topography CP: Developmental biology cardiac ultrastructure oxidative phosphorylation adult heart like cardiac maturation hiPSC derived cardiomyocytes |
Language | English |
License | This is an open access article under the CC BY-NC-ND license. Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c474t-c84efb3cf00dfcd55803aecec50eddf6082836ee61bc888dee0908dbba24d4733 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0002-2877-234X 0000-0003-2605-4325 0000-0003-0031-7799 0000-0002-6064-2860 |
OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.1016/j.celrep.2022.111146 |
PMID | 35905711 |
PQID | 2696861232 |
PQPubID | 23479 |
PageCount | 1 |
ParticipantIDs | doaj_primary_oai_doaj_org_article_0dbf0aa911234cc5aa6b863a486822f4 proquest_miscellaneous_2696861232 crossref_primary_10_1016_j_celrep_2022_111146 pubmed_primary_35905711 elsevier_sciencedirect_doi_10_1016_j_celrep_2022_111146 |
PublicationCentury | 2000 |
PublicationDate | 2022-07-26 |
PublicationDateYYYYMMDD | 2022-07-26 |
PublicationDate_xml | – month: 07 year: 2022 text: 2022-07-26 day: 26 |
PublicationDecade | 2020 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States |
PublicationTitle | Cell reports (Cambridge) |
PublicationTitleAlternate | Cell Rep |
PublicationYear | 2022 |
Publisher | Elsevier Inc Elsevier |
Publisher_xml | – name: Elsevier Inc – name: Elsevier |
References | McLellan, Skelly, Dona, Squiers, Farrugia, Gaynor, Cohen, Pandey, Diep, Vinh (bib71) 2020; 142 Barbuti, Benzoni, Campostrini, Dell'Era (bib8) 2016; 245 Fischer, Myers, Gardel, Waterman (bib28) 2012; 7 Cho, Lee, Tampakakis, Murphy, Andersen, Uosaki, Chelko, Chakir, Hong, Seo (bib18) 2017; 18 Guo, Pu (bib32) 2020; 126 Kolwicz, Tian (bib53) 2011; 90 Jin, Han, Platisa, Wooltorton, Cohen, Pieribone (bib41) 2012; 75 Akhmedov, LeNail, Bertoni, Kwee, Fraenkel, Montemanni (bib3) 2017; 10335 Smith, Yoo, Yi, Ahn, Lee, Shao, Nagornyak, Laflamme, Murry, Kim (bib93) 2017; 53 Ingwall (bib40) 2009; 81 Mamidi, Prawiro, Seymour, de Lichtenberg, Jackson, Serup, Semb (bib68) 2018; 564 Bedada, Wheelwright, Metzger (bib10) 2016; 1863 Patra, Ricciardi, Engel (bib76) 2012; 33 Meyer, Dick (bib72) 2010; 13 Rossi (bib80) 1998; 16 Tanner, Goglia, Wei, Sehgal, Parsons, Park, White, Toettcher, Rabinowitz (bib98) 2018; 7 Kedaigle, Fraenkel (bib46) 2018; 1711 Lopaschuk, Ussher, Folmes, Jaswal, Stanley (bib63) 2010; 90 Chen, Wardill, Sun, Pulver, Renninger, Baohan, Schreiter, Kerr, Orger, Jayaraman (bib17) 2013; 499 Kshitiz, Afzal, Kim, Levchenko (bib54) 2014; 32 Yang, Pabon, Murry (bib109) 2014; 114 Choy, Boon, Bertin, Fullwood (bib20) 2015; 2 Madamanchi, Runge (bib67) 2013; 61 He, Hu, Wilson, Wu, Feng, Xia, Churko, Qu, Chang, Wu (bib35) 2016; 9 Mammoto, Ingber (bib69) 2010; 137 Sewanan, Schwan, Kluger, Park, Jacoby, Qyang, Campbell (bib88) 2019; 4 Friedman, Nguyen, Lukowski, Helfer, Chiu, Miklas, Levy, Suo, Han, Osteil (bib29) 2018; 23 Wang, Pelham (bib105) 1998; 298 Doenst, Nguyen, Abel (bib25) 2013; 113 Ahmed, Anzai, Chanthra, Uosaki (bib2) 2020; 8 Schwach, Passier (bib86) 2019; 7 Gintant, Burridge, Gepstein, Harding, Herron, Hong, Jalife, Wu (bib30) 2019; 125 Huntley, Sawford, Mutowo-Meullenet, Shypitsyna, Bonilla, Martin, O'Donovan (bib39) 2015; 43 Patra, Diehl, Ferrazzi, van Amerongen, Novoyatleva, Schaefer, Mühlfeld, Jungblut, Engel (bib75) 2011; 138 Feyen, McKeithan, Bruyneel, Spiering, Hörmann, Ulmer, Zhang, Briganti, Schweizer, Hegyi (bib27) 2020; 32 Hubbi, Kshitiz, Gilkes, Gilkes, Rey, Wong, Luo, Kim, Dang, Levchenko, Semenza (bib38) 2013; 6 Burgoyne, Mongue-Din, Eaton, Shah (bib13) 2012; 111 Stanley, Recchia, Lopaschuk (bib94) 2005; 85 Liu, Lieu, Siu, Fu, Tse, Li (bib59) 2009; 297 Wixon, Kell (bib107) 2000; 17 Weinberger, Mannhardt, Eschenhagen (bib106) 2017; 120 Phillips, Sprouse, Roby (bib77) 2014; 4 Khan, Xu, Hua, Johnson, Belevych, Janssen, Gyorke, Guan, Angelos (bib48) 2015; 10 Salabei, Gibb, Hill (bib83) 2014; 9 Kannan, Vasan, Huang, Haziza, Li, Inan, Schnitzer, Pieribone (bib44) 2018; 15 López-Acosta, de Los Angeles Fortis-Barrera, Barrios-Maya, Ramírez, Aguilar, El-Hafidi (bib64) 2018; 2018 Aquilano, Baldelli, Ciriolo (bib4) 2014; 5 Picard, Taivassalo, Gouspillou, Hepple (bib78) 2011; 589 Kshitiz, Hubbi, Ahn, Downey, Afzal, Kim, Rey, Chang, Kundu, Semenza (bib55) 2012; 5 Slenter, Kutmon, Hanspers, Riutta, Windsor, Nunes, Mélius, Cirillo, Coort, Digles (bib92) 2018; 46 Caulfield, Janicki (bib16) 1997; 5 Harris, Clark, Ireland, Lomax, Ashburner, Foulger, Eilbeck, Lewis, Marshall, Mungall (bib34) 2004; 32 Passier, Orlova, Mummery (bib74) 2016; 18 Subramanian, Tamayo, Mootha, Mukherjee, Ebert, Gillette, Paulovich, Pomeroy, Golub, Lander, Mesirov (bib96) 2005; 102 Aratyn-Schaus, Oakes, Stricker, Winter, Gardel (bib5) 2010 Hom, Quintanilla, Hoffman, de Mesy Bentley, Molkentin, Sheu, Porter (bib36) 2011; 21 Archer, Robinson, Drawnel, Roderick (bib6) 2017; 36 Barth, Stämmler, Speiser, Schaper (bib9) 1992; 24 Liu, Tian, Zhao, Chen, Lei, Wang, Ma (bib60) 2015; 26 Liu, Acín-Peréz, Geghman, Manfredi, Lu, Li (bib61) 2011; 108 Yu, Lee, Lin, Lin, Wu, Tsai (bib110) 2014; 20 Carson, Hnilova, Yang, Nemeth, Tsui, Smith, Jiao, Regnier, Murry, Tamerler, Kim (bib15) 2016; 8 Gutscher, Pauleau, Marty, Brach, Wabnitz, Samstag, Meyer, Dick (bib33) 2008; 5 Dias, Pinto, Santos, Fernandes, Fernandes, Diogo, Prieto, Cabral (bib24) 2018; 499 Marian, Braunwald (bib70) 2017; 121 Lundy, Zhu, Regnier, Laflamme (bib65) 2013; 22 Lunt, Vander Heiden (bib66) 2011; 27 Bienstock, Goemans, Simchilevi, Williamson (bib12) 1993; 59 Hu, Linders, Yamak, Correia, Kijlstra, Garakani, Xiao, Milan, van der Meer, Serra (bib37) 2018; 123 Choi, Smith, Williams, Matsubara, Choi, Kim, Kim, Choi, Kim (bib19) 2020; 30 Feaster, Cadar, Wang, Williams, Chun, Hempel, Bloodworth, Merryman, Lim, Wu (bib26) 2015; 117 Stark, Breitkreutz, Reguly, Boucher, Breitkreutz, Tyers (bib95) 2006; 34 Paige, Plonowska, Xu, Wu (bib73) 2015; 116 Knoll, Ali, Saif (bib51) 2014 Santos, Anilkumar, Zhang, Brewer, Shah (bib84) 2011; 50 Afzal, Chan, Karakas, Woldemichael, Vakrou, Guan, Rathmell, Wahl, Pomper, Foster (bib1) 2017; 2 Bers (bib11) 2002; 415 Wrighton, Klim, Hernandez, Koonce, Kamp, Kiessling (bib108) 2014; 111 Kim, Kshitiz, Smith, Smith, Kim, Ahn, Kim, Marbán, Suh, Levchenko (bib49) 2012; 4 Lopaschuk, Jaswal (bib62) 2010; 56 Shi, Tien, de Haan, Louisse, Rietjens, Bouwmeester (bib90) 2020; 67 Liu, Laksman, Backx (bib58) 2016; 96 Jung, Hu, Domian, Ogle (bib42) 2015; 5 Kim, Dalal, Young, Legato, Weisfeldt, D'Armiento (bib50) 2000; 106 Correia, Koshkin, Duarte, Hu, Teixeira, Domian, Serra, Alves (bib21) 2017; 7 de las Fuentes, Herrero, Peterson, Kelly, Gropler, Dávila-Román (bib23) 2003; 41 Schwer, Verdin (bib87) 2008; 7 Ruan, Tulloch, Razumova, Saiget, Muskheli, Pabon, Reinecke, Regnier, Murry (bib81) 2016; 134 Kolberg, Raudvere, Kuzmin, Vilo, Peterson (bib52) 2020; 9 Vining, Mooney (bib104) 2017; 18 Kaiser, Kant, Minor, Coulombe (bib43) 2019; 5 Sartiani, Bettiol, Stillitano, Mugelli, Cerbai, Jaconi (bib85) 2007; 25 Silva, Pereira, Fonseca, Pinto-do-Ó, Nascimento (bib91) 2020; 8 Tohyama, Hattori, Sano, Hishiki, Nagahata, Matsuura, Hashimoto, Suzuki, Yamashita, Satoh (bib101) 2013; 12 Burridge, Matsa, Shukla, Lin, Churko, Ebert, Lan, Diecke, Huber, Mordwinkin (bib14) 2014; 11 Ronaldson-Bouchard, Ma, Yeager, Chen, Song, Sirabella, Morikawa, Teles, Yazawa, Vunjak-Novakovic (bib79) 2018; 556 Lewandowski, Rozwadowska, Kolanowski, Malcher, Zimna, Rugowska, Fiedorowicz, Łabędź, Kubaszewski, Chojnacka (bib57) 2018; 27 Uosaki, Cahan, Lee, Wang, Miyamoto, Fernandez, Kass, Kwon (bib103) 2015; 13 Zhao, Cai, Peng, Liang, Xi, Li, Chen, Yu, Chen (bib111) 2019; 23 Crowder, Liang, Rath, Park, Maltais, Pintauro, Hofmeister, Lim, Wang, Sung (bib22) 2013; 8 Thielicke, Stamhuis (bib99) 2014; 2 Kumar, Sridharan, Palaniappan, Dougherty, Czirok, Isai, Mergaye, Angelos, Powell, Khan (bib56) 2020; 8 Goversen, van der Heyden, van Veen, de Boer (bib31) 2018; 183 Tu, Chao, Wu (bib102) 2018; 123 Ayad, Kaushik, Weaver (bib7) 2019; 374 Karakikes, Ameen, Termglinchan, Wu (bib45) 2015; 117 Sabass, Gardel, Waterman, Schwarz (bib82) 2008; 94 Shadrin, Allen, Qian, Jackman, Carlson, Juhas, Bursac (bib89) 2017; 8 Thompson, Nadal-Ginard, Mahdavi (bib100) 1991; 266 Keung, Boheler, Li (bib47) 2014; 5 Sung, Su, Ling, Kumar, Chang, Hsu, Higuchi (bib97) 2020; 253 Kaiser (10.1016/j.celrep.2022.111146_bib43) 2019; 5 Burridge (10.1016/j.celrep.2022.111146_bib14) 2014; 11 Lewandowski (10.1016/j.celrep.2022.111146_bib57) 2018; 27 Tu (10.1016/j.celrep.2022.111146_bib102) 2018; 123 Hu (10.1016/j.celrep.2022.111146_bib37) 2018; 123 Sartiani (10.1016/j.celrep.2022.111146_bib85) 2007; 25 Vining (10.1016/j.celrep.2022.111146_bib104) 2017; 18 Tanner (10.1016/j.celrep.2022.111146_bib98) 2018; 7 Correia (10.1016/j.celrep.2022.111146_bib21) 2017; 7 Bienstock (10.1016/j.celrep.2022.111146_bib12) 1993; 59 Sewanan (10.1016/j.celrep.2022.111146_bib88) 2019; 4 Afzal (10.1016/j.celrep.2022.111146_bib1) 2017; 2 Kedaigle (10.1016/j.celrep.2022.111146_bib46) 2018; 1711 Kolwicz (10.1016/j.celrep.2022.111146_bib53) 2011; 90 Archer (10.1016/j.celrep.2022.111146_bib6) 2017; 36 Sabass (10.1016/j.celrep.2022.111146_bib82) 2008; 94 Aquilano (10.1016/j.celrep.2022.111146_bib4) 2014; 5 Barth (10.1016/j.celrep.2022.111146_bib9) 1992; 24 de las Fuentes (10.1016/j.celrep.2022.111146_bib23) 2003; 41 Dias (10.1016/j.celrep.2022.111146_bib24) 2018; 499 Huntley (10.1016/j.celrep.2022.111146_bib39) 2015; 43 Rossi (10.1016/j.celrep.2022.111146_bib80) 1998; 16 Wang (10.1016/j.celrep.2022.111146_bib105) 1998; 298 Ruan (10.1016/j.celrep.2022.111146_bib81) 2016; 134 Tohyama (10.1016/j.celrep.2022.111146_bib101) 2013; 12 Chen (10.1016/j.celrep.2022.111146_bib17) 2013; 499 Meyer (10.1016/j.celrep.2022.111146_bib72) 2010; 13 Cho (10.1016/j.celrep.2022.111146_bib18) 2017; 18 Ahmed (10.1016/j.celrep.2022.111146_bib2) 2020; 8 Santos (10.1016/j.celrep.2022.111146_bib84) 2011; 50 Bers (10.1016/j.celrep.2022.111146_bib11) 2002; 415 Kolberg (10.1016/j.celrep.2022.111146_bib52) 2020; 9 Wixon (10.1016/j.celrep.2022.111146_bib107) 2000; 17 Feaster (10.1016/j.celrep.2022.111146_bib26) 2015; 117 Hubbi (10.1016/j.celrep.2022.111146_bib38) 2013; 6 Weinberger (10.1016/j.celrep.2022.111146_bib106) 2017; 120 Subramanian (10.1016/j.celrep.2022.111146_bib96) 2005; 102 Mammoto (10.1016/j.celrep.2022.111146_bib69) 2010; 137 McLellan (10.1016/j.celrep.2022.111146_bib71) 2020; 142 Liu (10.1016/j.celrep.2022.111146_bib60) 2015; 26 Lopaschuk (10.1016/j.celrep.2022.111146_bib63) 2010; 90 Barbuti (10.1016/j.celrep.2022.111146_bib8) 2016; 245 Kim (10.1016/j.celrep.2022.111146_bib50) 2000; 106 Schwer (10.1016/j.celrep.2022.111146_bib87) 2008; 7 Gintant (10.1016/j.celrep.2022.111146_bib30) 2019; 125 Choi (10.1016/j.celrep.2022.111146_bib19) 2020; 30 He (10.1016/j.celrep.2022.111146_bib35) 2016; 9 Lunt (10.1016/j.celrep.2022.111146_bib66) 2011; 27 Passier (10.1016/j.celrep.2022.111146_bib74) 2016; 18 Bedada (10.1016/j.celrep.2022.111146_bib10) 2016; 1863 Marian (10.1016/j.celrep.2022.111146_bib70) 2017; 121 Fischer (10.1016/j.celrep.2022.111146_bib28) 2012; 7 Doenst (10.1016/j.celrep.2022.111146_bib25) 2013; 113 Smith (10.1016/j.celrep.2022.111146_bib93) 2017; 53 Yang (10.1016/j.celrep.2022.111146_bib109) 2014; 114 Lundy (10.1016/j.celrep.2022.111146_bib65) 2013; 22 Caulfield (10.1016/j.celrep.2022.111146_bib16) 1997; 5 Lopaschuk (10.1016/j.celrep.2022.111146_bib62) 2010; 56 Aratyn-Schaus (10.1016/j.celrep.2022.111146_bib5) 2010 Liu (10.1016/j.celrep.2022.111146_bib61) 2011; 108 Picard (10.1016/j.celrep.2022.111146_bib78) 2011; 589 Stanley (10.1016/j.celrep.2022.111146_bib94) 2005; 85 Hom (10.1016/j.celrep.2022.111146_bib36) 2011; 21 Salabei (10.1016/j.celrep.2022.111146_bib83) 2014; 9 Carson (10.1016/j.celrep.2022.111146_bib15) 2016; 8 Goversen (10.1016/j.celrep.2022.111146_bib31) 2018; 183 Patra (10.1016/j.celrep.2022.111146_bib76) 2012; 33 Wrighton (10.1016/j.celrep.2022.111146_bib108) 2014; 111 Ronaldson-Bouchard (10.1016/j.celrep.2022.111146_bib79) 2018; 556 Mamidi (10.1016/j.celrep.2022.111146_bib68) 2018; 564 Akhmedov (10.1016/j.celrep.2022.111146_bib3) 2017; 10335 Gutscher (10.1016/j.celrep.2022.111146_bib33) 2008; 5 Ayad (10.1016/j.celrep.2022.111146_bib7) 2019; 374 Jin (10.1016/j.celrep.2022.111146_bib41) 2012; 75 Phillips (10.1016/j.celrep.2022.111146_bib77) 2014; 4 Burgoyne (10.1016/j.celrep.2022.111146_bib13) 2012; 111 Shadrin (10.1016/j.celrep.2022.111146_bib89) 2017; 8 Silva (10.1016/j.celrep.2022.111146_bib91) 2020; 8 López-Acosta (10.1016/j.celrep.2022.111146_bib64) 2018; 2018 Slenter (10.1016/j.celrep.2022.111146_bib92) 2018; 46 Kim (10.1016/j.celrep.2022.111146_bib49) 2012; 4 Knoll (10.1016/j.celrep.2022.111146_bib51) 2014 Kumar (10.1016/j.celrep.2022.111146_bib56) 2020; 8 Feyen (10.1016/j.celrep.2022.111146_bib27) 2020; 32 Sung (10.1016/j.celrep.2022.111146_bib97) 2020; 253 Choy (10.1016/j.celrep.2022.111146_bib20) 2015; 2 Kannan (10.1016/j.celrep.2022.111146_bib44) 2018; 15 Madamanchi (10.1016/j.celrep.2022.111146_bib67) 2013; 61 Zhao (10.1016/j.celrep.2022.111146_bib111) 2019; 23 Yu (10.1016/j.celrep.2022.111146_bib110) 2014; 20 Keung (10.1016/j.celrep.2022.111146_bib47) 2014; 5 Karakikes (10.1016/j.celrep.2022.111146_bib45) 2015; 117 Thielicke (10.1016/j.celrep.2022.111146_bib99) 2014; 2 Uosaki (10.1016/j.celrep.2022.111146_bib103) 2015; 13 Schwach (10.1016/j.celrep.2022.111146_bib86) 2019; 7 Stark (10.1016/j.celrep.2022.111146_bib95) 2006; 34 Guo (10.1016/j.celrep.2022.111146_bib32) 2020; 126 Patra (10.1016/j.celrep.2022.111146_bib75) 2011; 138 Khan (10.1016/j.celrep.2022.111146_bib48) 2015; 10 Thompson (10.1016/j.celrep.2022.111146_bib100) 1991; 266 Kshitiz (10.1016/j.celrep.2022.111146_bib54) 2014; 32 Kshitiz (10.1016/j.celrep.2022.111146_bib55) 2012; 5 Crowder (10.1016/j.celrep.2022.111146_bib22) 2013; 8 Friedman (10.1016/j.celrep.2022.111146_bib29) 2018; 23 Paige (10.1016/j.celrep.2022.111146_bib73) 2015; 116 Ingwall (10.1016/j.celrep.2022.111146_bib40) 2009; 81 Shi (10.1016/j.celrep.2022.111146_bib90) 2020; 67 Jung (10.1016/j.celrep.2022.111146_bib42) 2015; 5 Harris (10.1016/j.celrep.2022.111146_bib34) 2004; 32 Liu (10.1016/j.celrep.2022.111146_bib58) 2016; 96 Liu (10.1016/j.celrep.2022.111146_bib59) 2009; 297 |
References_xml | – volume: 90 start-page: 207 year: 2010 end-page: 258 ident: bib63 article-title: Myocardial fatty acid metabolism in health and disease publication-title: Physiol. Rev. contributor: fullname: Stanley – volume: 22 start-page: 1991 year: 2013 end-page: 2002 ident: bib65 article-title: Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells publication-title: Stem Cells Dev. contributor: fullname: Laflamme – volume: 36 start-page: 240 year: 2017 end-page: 254 ident: bib6 article-title: Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors publication-title: Cell. Signal. contributor: fullname: Roderick – volume: 21 start-page: 469 year: 2011 end-page: 478 ident: bib36 article-title: The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation publication-title: Dev. Cell contributor: fullname: Porter – volume: 5 start-page: 95 year: 1997 end-page: 113 ident: bib16 article-title: Structure and function of myocardial fibrillar collagen publication-title: Technol. Health Care contributor: fullname: Janicki – volume: 96 start-page: 253 year: 2016 end-page: 273 ident: bib58 article-title: The electrophysiological development of cardiomyocytes publication-title: Adv. Drug Deliv. Rev. contributor: fullname: Backx – volume: 5 start-page: ra41 year: 2012 ident: bib55 article-title: Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors publication-title: Sci. Signal. contributor: fullname: Semenza – volume: 27 start-page: 441 year: 2011 end-page: 464 ident: bib66 article-title: Aerobic glycolysis: meeting the metabolic requirements of cell proliferation publication-title: Annu. Rev. Cell Dev. Biol. contributor: fullname: Vander Heiden – volume: 75 start-page: 779 year: 2012 end-page: 785 ident: bib41 article-title: Single action potentials and subthreshold electrical events imaged in neurons with a fluorescent protein voltage probe publication-title: Neuron contributor: fullname: Pieribone – volume: 183 start-page: 127 year: 2018 end-page: 136 ident: bib31 article-title: The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: special focus on Ik1 publication-title: Pharmacol. Ther. contributor: fullname: de Boer – volume: 18 start-page: 309 year: 2016 end-page: 321 ident: bib74 article-title: Complex tissue and disease modeling using hiPSCs publication-title: Cell Stem Cell contributor: fullname: Mummery – volume: 5 start-page: 887 year: 2019 end-page: 899 ident: bib43 article-title: Optimizing blended collagen-fibrin hydrogels for cardiac tissue engineering with human iPSC-derived cardiomyocytes publication-title: ACS Biomater. Sci. Eng. contributor: fullname: Coulombe – volume: 33 start-page: 4327 year: 2012 end-page: 4335 ident: bib76 article-title: The functional properties of nephronectin: an adhesion molecule for cardiac tissue engineering publication-title: Biomaterials contributor: fullname: Engel – volume: 15 start-page: 1108 year: 2018 end-page: 1116 ident: bib44 article-title: Fast, in vivo voltage imaging using a red fluorescent indicator publication-title: Nat. Methods contributor: fullname: Pieribone – volume: 134 start-page: 1557 year: 2016 end-page: 1567 ident: bib81 article-title: Mechanical stress conditioning and electrical stimulation promote contractility and force maturation of induced pluripotent stem cell-derived human cardiac tissue publication-title: Circulation contributor: fullname: Murry – volume: 18 start-page: 728 year: 2017 end-page: 742 ident: bib104 article-title: Mechanical forces direct stem cell behaviour in development and regeneration publication-title: Nat. Rev. Mol. Cell Biol. contributor: fullname: Mooney – volume: 2 year: 2014 ident: bib99 article-title: PIVlab -towards user-friendly, affordable and accurate digital particle image velocimetry in MATLAB publication-title: J. Open Res. Software contributor: fullname: Stamhuis – volume: 11 start-page: 855 year: 2014 end-page: 860 ident: bib14 article-title: Chemically defined generation of human cardiomyocytes publication-title: Nat. Methods contributor: fullname: Mordwinkin – volume: 117 start-page: 80 year: 2015 end-page: 88 ident: bib45 article-title: Human induced pluripotent stem cell-derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes publication-title: Circ. Res. contributor: fullname: Wu – volume: 46 start-page: D661 year: 2018 end-page: D667 ident: bib92 article-title: WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research publication-title: Nucleic Acids Res. contributor: fullname: Digles – volume: 415 start-page: 198 year: 2002 end-page: 205 ident: bib11 article-title: Cardiac excitation-contraction coupling publication-title: Nature contributor: fullname: Bers – volume: 2 start-page: 150063 year: 2015 ident: bib20 article-title: A resource of ribosomal RNA-depleted RNA-Seq data from different normal adult and fetal human tissues publication-title: Sci. Data contributor: fullname: Fullwood – volume: 81 start-page: 412 year: 2009 end-page: 419 ident: bib40 article-title: Energy metabolism in heart failure and remodelling publication-title: Cardiovasc. Res. contributor: fullname: Ingwall – volume: 32 start-page: 107925 year: 2020 ident: bib27 article-title: Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes publication-title: Cell Rep. contributor: fullname: Hegyi – volume: 297 start-page: C152 year: 2009 end-page: C159 ident: bib59 article-title: Facilitated maturation of Ca2+ handling properties of human embryonic stem cell-derived cardiomyocytes by calsequestrin expression publication-title: Am. J. Physiol. Cell Physiol. contributor: fullname: Li – volume: 53 start-page: 7412 year: 2017 end-page: 7415 ident: bib93 article-title: Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering publication-title: Chem. Commun. contributor: fullname: Kim – volume: 32 start-page: 1999 year: 2014 end-page: 2007 ident: bib54 article-title: Concise review: mechanotransduction via p190RhoGAP regulates a switch between cardiomyogenic and endothelial lineages in adult cardiac progenitors publication-title: Stem Cell. contributor: fullname: Levchenko – volume: 116 start-page: 341 year: 2015 end-page: 353 ident: bib73 article-title: Molecular regulation of cardiomyocyte differentiation publication-title: Circ. Res. contributor: fullname: Wu – volume: 4 start-page: 3887 year: 2014 ident: bib77 article-title: Simultaneous quantification of mitochondrial DNA copy number and deletion ratio: a multiplex real-time PCR assay publication-title: Sci. Rep. contributor: fullname: Roby – volume: 27 start-page: 1047 year: 2018 end-page: 1067 ident: bib57 article-title: The impact of in vitro cell culture duration on the maturation of human cardiomyocytes derived from induced pluripotent stem cells of myogenic origin publication-title: Cell Transplant. contributor: fullname: Chojnacka – volume: 8 start-page: 1825 year: 2017 ident: bib89 article-title: Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues publication-title: Nat. Commun. contributor: fullname: Bursac – volume: 108 start-page: 12920 year: 2011 end-page: 12924 ident: bib61 article-title: Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Li – volume: 20 start-page: 1896 year: 2014 end-page: 1907 ident: bib110 article-title: Electrospun PLGA fibers incorporated with functionalized biomolecules for cardiac tissue engineering publication-title: Tissue Eng. Part A contributor: fullname: Tsai – volume: 13 start-page: 1705 year: 2015 end-page: 1716 ident: bib103 article-title: Transcriptional landscape of cardiomyocyte maturation publication-title: Cell Rep. contributor: fullname: Kwon – volume: 5 start-page: 17 year: 2014 ident: bib47 article-title: Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes publication-title: Stem Cell Res. Ther. contributor: fullname: Li – volume: 5 start-page: 196 year: 2014 ident: bib4 article-title: Glutathione: new roles in redox signaling for an old antioxidant publication-title: Front. Pharmacol. contributor: fullname: Ciriolo – volume: 32 start-page: D258 year: 2004 end-page: D261 ident: bib34 article-title: The Gene Ontology (GO) database and informatics resource publication-title: Nucleic Acids Res. contributor: fullname: Mungall – volume: 34 start-page: D535 year: 2006 end-page: D539 ident: bib95 article-title: BioGRID: a general repository for interaction datasets publication-title: Nucleic Acids Res. contributor: fullname: Tyers – volume: 13 start-page: 621 year: 2010 end-page: 650 ident: bib72 article-title: Fluorescent protein-based redox probes publication-title: Antioxid. Redox Signal. contributor: fullname: Dick – volume: 266 start-page: 22678 year: 1991 end-page: 22688 ident: bib100 article-title: A MyoD1-independent muscle-specific enhancer controls the expression of the beta-myosin heavy chain gene in skeletal and cardiac muscle cells publication-title: J. Biol. Chem. contributor: fullname: Mahdavi – volume: 24 start-page: 669 year: 1992 end-page: 681 ident: bib9 article-title: Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man publication-title: J. Mol. Cell. Cardiol. contributor: fullname: Schaper – volume: 9 start-page: 110 year: 2016 end-page: 118 ident: bib35 article-title: Systematic characterization of long noncoding RNAs reveals the contrasting coordination of cis- and trans-molecular regulation in human fetal and adult hearts publication-title: Circ. Cardiovasc. Genet. contributor: fullname: Wu – volume: 120 start-page: 1487 year: 2017 end-page: 1500 ident: bib106 article-title: Engineering cardiac muscle tissue: a maturating field of research publication-title: Circ. Res. contributor: fullname: Eschenhagen – volume: 113 start-page: 709 year: 2013 end-page: 724 ident: bib25 article-title: Cardiac metabolism in heart failure: implications beyond ATP production publication-title: Circ. Res. contributor: fullname: Abel – volume: 26 start-page: 105 year: 2015 end-page: 114 ident: bib60 article-title: Porous nanofibrous poly(L-lactic acid) scaffolds supporting cardiovascular progenitor cells for cardiac tissue engineering publication-title: Acta Biomater. contributor: fullname: Ma – volume: 298 start-page: 489 year: 1998 end-page: 496 ident: bib105 article-title: Preparation of a flexible, porous polyacrylamide substrate for mechanical studies of cultured cells publication-title: Methods Enzymol. contributor: fullname: Pelham – volume: 12 start-page: 127 year: 2013 end-page: 137 ident: bib101 article-title: Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes publication-title: Cell Stem Cell contributor: fullname: Satoh – volume: 564 start-page: 114 year: 2018 end-page: 118 ident: bib68 article-title: Mechanosignalling via integrins directs fate decisions of pancreatic progenitors publication-title: Nature contributor: fullname: Semb – volume: 125 start-page: e75 year: 2019 end-page: e92 ident: bib30 article-title: Use of human induced pluripotent stem cell-derived cardiomyocytes in preclinical cancer drug cardiotoxicity testing: a scientific statement from the American heart association publication-title: Circ. Res. contributor: fullname: Wu – volume: 123 start-page: 512 year: 2018 end-page: 514 ident: bib102 article-title: Strategies for improving the maturity of human induced pluripotent stem cell-derived cardiomyocytes publication-title: Circ. Res. contributor: fullname: Wu – volume: 9 year: 2020 ident: bib52 article-title: gprofiler2 -- an R Package for Gene List Functional Enrichment Analysis and Namespace Conversion Toolset g:Profiler publication-title: F1000Res. contributor: fullname: Peterson – volume: 117 start-page: 995 year: 2015 end-page: 1000 ident: bib26 article-title: Matrigel mattress: a method for the generation of single contracting human-induced pluripotent stem cell-derived cardiomyocytes publication-title: Circ. Res. contributor: fullname: Wu – volume: 85 start-page: 1093 year: 2005 end-page: 1129 ident: bib94 article-title: Myocardial substrate metabolism in the normal and failing heart publication-title: Physiol. Rev. contributor: fullname: Lopaschuk – volume: 114 start-page: 511 year: 2014 end-page: 523 ident: bib109 article-title: Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes publication-title: Circ. Res. contributor: fullname: Murry – start-page: 2173 year: 2010 ident: bib5 article-title: Preparation of complaint matrices for quantifying cellular contraction publication-title: J. Vis. Exp. contributor: fullname: Gardel – volume: 59 start-page: 413 year: 1993 end-page: 420 ident: bib12 article-title: A note on the prize collecting traveling salesman problem publication-title: Math. Program. contributor: fullname: Williamson – volume: 7 start-page: 3566 year: 2019 end-page: 3580 ident: bib86 article-title: Native cardiac environment and its impact on engineering cardiac tissue publication-title: Biomater. Sci. contributor: fullname: Passier – volume: 94 start-page: 207 year: 2008 end-page: 220 ident: bib82 article-title: High resolution traction force microscopy based on experimental and computational advances publication-title: Biophys. J. contributor: fullname: Schwarz – volume: 30 start-page: 1910660 year: 2020 ident: bib19 article-title: Nanopatterned Nafion microelectrode arrays for in vitro cardiac electrophysiology publication-title: Adv. Funct. Mater. contributor: fullname: Kim – volume: 8 start-page: 1763 year: 2013 end-page: 1776 ident: bib22 article-title: Poly(epsilon-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells publication-title: Nanomedicine (Lond) contributor: fullname: Sung – volume: 7 start-page: 104 year: 2008 end-page: 112 ident: bib87 article-title: Conserved metabolic regulatory functions of sirtuins publication-title: Cell Metab. contributor: fullname: Verdin – volume: 7 start-page: 2056 year: 2012 end-page: 2066 ident: bib28 article-title: Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior publication-title: Nat. Protoc. contributor: fullname: Waterman – volume: 67 start-page: 104891 year: 2020 ident: bib90 article-title: Evaluation of in vitro models of stem cell-derived cardiomyocytes to screen for potential cardiotoxicity of chemicals publication-title: Toxicol. Vitro contributor: fullname: Bouwmeester – volume: 6 start-page: ra10 year: 2013 ident: bib38 article-title: A nontranscriptional role for HIF-1alpha as a direct inhibitor of DNA replication publication-title: Sci. Signal. contributor: fullname: Semenza – volume: 111 start-page: 18126 year: 2014 end-page: 18131 ident: bib108 article-title: Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Kiessling – volume: 5 start-page: 18705 year: 2015 ident: bib42 article-title: An integrated statistical model for enhanced murine cardiomyocyte differentiation via optimized engagement of 3D extracellular matrices publication-title: Sci. Rep. contributor: fullname: Ogle – volume: 245 start-page: 1145 year: 2016 end-page: 1158 ident: bib8 article-title: Human derived cardiomyocytes: a decade of knowledge after the discovery of induced pluripotent stem cells publication-title: Dev. Dynam. contributor: fullname: Dell'Era – volume: 111 start-page: 1091 year: 2012 end-page: 1106 ident: bib13 article-title: Redox signaling in cardiac physiology and pathology publication-title: Circ. Res. contributor: fullname: Shah – volume: 2 start-page: 543 year: 2017 end-page: 560 ident: bib1 article-title: Cardiosphere-derived cells demonstrate metabolic flexibility that is influenced by adhesion status publication-title: JACC. Basic Transl. Sci. contributor: fullname: Foster – volume: 102 start-page: 15545 year: 2005 end-page: 15550 ident: bib96 article-title: Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Mesirov – volume: 123 start-page: 1066 year: 2018 end-page: 1079 ident: bib37 article-title: Metabolic maturation of human pluripotent stem cell-derived cardiomyocytes by inhibition of HIF1alpha and LDHA publication-title: Circ. Res. contributor: fullname: Serra – volume: 23 start-page: 2489 year: 2019 end-page: 2504 ident: bib111 article-title: JS-K induces reactive oxygen species-dependent anti-cancer effects by targeting mitochondria respiratory chain complexes in gastric cancer publication-title: J. Cell Mol. Med. contributor: fullname: Chen – volume: 4 start-page: 495 year: 2019 end-page: 505 ident: bib88 article-title: Extracellular matrix from hypertrophic myocardium provokes impaired twitch dynamics in healthy cardiomyocytes publication-title: JACC. Basic Transl. Sci. contributor: fullname: Campbell – volume: 18 start-page: 571 year: 2017 end-page: 582 ident: bib18 article-title: Neonatal transplantation confers maturation of PSC-derived cardiomyocytes conducive to modeling cardiomyopathy publication-title: Cell Rep. contributor: fullname: Seo – volume: 8 start-page: 621644 year: 2020 ident: bib91 article-title: Bearing my heart: the role of extracellular matrix on cardiac development, homeostasis, and injury response publication-title: Front. Cell Dev. Biol. contributor: fullname: Nascimento – volume: 142 start-page: 1448 year: 2020 end-page: 1463 ident: bib71 article-title: High-resolution transcriptomic profiling of the heart during chronic stress reveals cellular drivers of cardiac fibrosis and hypertrophy publication-title: Circulation contributor: fullname: Vinh – volume: 138 start-page: 4499 year: 2011 end-page: 4509 ident: bib75 article-title: Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish publication-title: Development contributor: fullname: Engel – volume: 106 start-page: 857 year: 2000 end-page: 866 ident: bib50 article-title: Disruption of the myocardial extracellular matrix leads to cardiac dysfunction publication-title: J. Clin. Invest. contributor: fullname: D'Armiento – volume: 499 start-page: 295 year: 2013 end-page: 300 ident: bib17 article-title: Ultrasensitive fluorescent proteins for imaging neuronal activity publication-title: Nature contributor: fullname: Jayaraman – volume: 499 start-page: 611 year: 2018 end-page: 617 ident: bib24 article-title: Biophysical study of human induced Pluripotent Stem Cell-Derived cardiomyocyte structural maturation during long-term culture publication-title: Biochem. Biophys. Res. Commun. contributor: fullname: Cabral – volume: 374 start-page: 20180215 year: 2019 ident: bib7 article-title: Tissue mechanics, an important regulator of development and disease publication-title: Philos. Trans. R. Soc. Lond. B Biol. Sci. contributor: fullname: Weaver – volume: 4 start-page: 1019 year: 2012 end-page: 1033 ident: bib49 article-title: Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration publication-title: Integr. Biol. contributor: fullname: Levchenko – volume: 16 start-page: 1031 year: 1998 end-page: 1041 ident: bib80 article-title: Pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans publication-title: J. Hypertens. contributor: fullname: Rossi – volume: 8 start-page: 178 year: 2020 ident: bib2 article-title: A brief review of current maturation methods for human induced pluripotent stem cells-derived cardiomyocytes publication-title: Front. Cell Dev. Biol. contributor: fullname: Uosaki – volume: 56 start-page: 130 year: 2010 end-page: 140 ident: bib62 article-title: Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation publication-title: J. Cardiovasc. Pharmacol. contributor: fullname: Jaswal – volume: 43 start-page: D1057 year: 2015 end-page: D1063 ident: bib39 article-title: The Goa database: gene Ontology annotation updates for 2015 publication-title: Nucleic Acids Res. contributor: fullname: O'Donovan – volume: 50 start-page: 777 year: 2011 end-page: 793 ident: bib84 article-title: Redox signaling in cardiac myocytes publication-title: Free Radic. Biol. Med. contributor: fullname: Shah – volume: 61 start-page: 473 year: 2013 end-page: 501 ident: bib67 article-title: Redox signaling in cardiovascular health and disease publication-title: Free Radic. Biol. Med. contributor: fullname: Runge – volume: 2018 start-page: 5835072 year: 2018 ident: bib64 article-title: Reactive oxygen species from NADPH oxidase and mitochondria participate in the proliferation of aortic smooth muscle cells from a model of metabolic syndrome publication-title: Oxid. Med. Cell. Longev. contributor: fullname: El-Hafidi – volume: 7 start-page: 49 year: 2018 end-page: 62.e8 ident: bib98 article-title: Four key steps control glycolytic flux in mammalian cells publication-title: Cell Syst. contributor: fullname: Rabinowitz – volume: 17 start-page: 48 year: 2000 end-page: 55 ident: bib107 article-title: The Kyoto encyclopedia of genes and genomes--KEGG publication-title: Yeast contributor: fullname: Kell – volume: 9 start-page: 421 year: 2014 end-page: 438 ident: bib83 article-title: Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis publication-title: Nat. Protoc. contributor: fullname: Hill – volume: 253 start-page: 120060 year: 2020 ident: bib97 article-title: Efficient differentiation of human pluripotent stem cells into cardiomyocytes on cell sorting thermoresponsive surface publication-title: Biomaterials contributor: fullname: Higuchi – volume: 41 start-page: 83 year: 2003 end-page: 87 ident: bib23 article-title: Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertensive heart disease publication-title: Hypertension contributor: fullname: Dávila-Román – volume: 121 start-page: 749 year: 2017 end-page: 770 ident: bib70 article-title: Hypertrophic cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy publication-title: Circ. Res. contributor: fullname: Braunwald – volume: 1863 start-page: 1829 year: 2016 end-page: 1838 ident: bib10 article-title: Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes publication-title: Biochim. Biophys. Acta contributor: fullname: Metzger – volume: 1711 start-page: 13 year: 2018 end-page: 26 ident: bib46 article-title: Discovering altered regulation and signaling through network-based integration of transcriptomic, epigenomic and proteomic tumor data publication-title: Methods Mol. Biol. contributor: fullname: Fraenkel – volume: 10335 start-page: 263 year: 2017 end-page: 276 ident: bib3 article-title: A fast prize-collecting steiner forest algorithm for functional analyses in biological networks publication-title: Lect. Notes Comput. Sc. contributor: fullname: Montemanni – volume: 10 start-page: e0126338 year: 2015 ident: bib48 article-title: Evaluation of changes in morphology and function of human induced pluripotent stem cell derived cardiomyocytes (HiPSC-CMs) cultured on an aligned-nanofiber cardiac patch publication-title: PLoS One contributor: fullname: Angelos – volume: 8 start-page: 21923 year: 2016 end-page: 21932 ident: bib15 article-title: Nanotopography-induced structural anisotropy and sarcomere development in human cardiomyocytes derived from induced pluripotent stem cells publication-title: ACS Appl. Mater. Interfaces contributor: fullname: Kim – volume: 8 start-page: 567842 year: 2020 ident: bib56 article-title: Scalable biomimetic coaxial aligned nanofiber cardiac patch: a potential model for "clinical trials in a dish publication-title: Front. Bioeng. Biotechnol. contributor: fullname: Khan – volume: 25 start-page: 1136 year: 2007 end-page: 1144 ident: bib85 article-title: Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach publication-title: Stem Cell. contributor: fullname: Jaconi – volume: 137 start-page: 1407 year: 2010 end-page: 1420 ident: bib69 article-title: Mechanical control of tissue and organ development publication-title: Development contributor: fullname: Ingber – volume: 23 start-page: 586 year: 2018 end-page: 598.e8 ident: bib29 article-title: Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation publication-title: Cell Stem Cell contributor: fullname: Osteil – volume: 589 start-page: 4413 year: 2011 end-page: 4421 ident: bib78 article-title: Mitochondria: isolation, structure and function publication-title: J. Physiol. contributor: fullname: Hepple – volume: 7 start-page: 8590 year: 2017 ident: bib21 article-title: Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells publication-title: Sci. Rep. contributor: fullname: Alves – volume: 556 start-page: 239 year: 2018 end-page: 243 ident: bib79 article-title: Advanced maturation of human cardiac tissue grown from pluripotent stem cells publication-title: Nature contributor: fullname: Vunjak-Novakovic – volume: 126 start-page: 1086 year: 2020 end-page: 1106 ident: bib32 article-title: Cardiomyocyte maturation: new phase in development publication-title: Circ. Res. contributor: fullname: Pu – volume: 5 start-page: 553 year: 2008 end-page: 559 ident: bib33 article-title: Real-time imaging of the intracellular glutathione redox potential publication-title: Nat. Methods contributor: fullname: Dick – start-page: 51873 year: 2014 ident: bib51 article-title: A novel method for localizing reporter fluorescent beads near the cell culture surface for traction force microscopy publication-title: J. Vis. Exp. contributor: fullname: Saif – volume: 90 start-page: 194 year: 2011 end-page: 201 ident: bib53 article-title: Glucose metabolism and cardiac hypertrophy publication-title: Cardiovasc. Res. contributor: fullname: Tian – volume: 7 start-page: 49 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib98 article-title: Four key steps control glycolytic flux in mammalian cells publication-title: Cell Syst. doi: 10.1016/j.cels.2018.06.003 contributor: fullname: Tanner – volume: 18 start-page: 309 year: 2016 ident: 10.1016/j.celrep.2022.111146_bib74 article-title: Complex tissue and disease modeling using hiPSCs publication-title: Cell Stem Cell doi: 10.1016/j.stem.2016.02.011 contributor: fullname: Passier – volume: 30 start-page: 1910660 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib19 article-title: Nanopatterned Nafion microelectrode arrays for in vitro cardiac electrophysiology publication-title: Adv. Funct. Mater. doi: 10.1002/adfm.201910660 contributor: fullname: Choi – volume: 4 start-page: 495 year: 2019 ident: 10.1016/j.celrep.2022.111146_bib88 article-title: Extracellular matrix from hypertrophic myocardium provokes impaired twitch dynamics in healthy cardiomyocytes publication-title: JACC. Basic Transl. Sci. doi: 10.1016/j.jacbts.2019.03.004 contributor: fullname: Sewanan – volume: 245 start-page: 1145 year: 2016 ident: 10.1016/j.celrep.2022.111146_bib8 article-title: Human derived cardiomyocytes: a decade of knowledge after the discovery of induced pluripotent stem cells publication-title: Dev. Dynam. doi: 10.1002/dvdy.24455 contributor: fullname: Barbuti – volume: 123 start-page: 512 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib102 article-title: Strategies for improving the maturity of human induced pluripotent stem cell-derived cardiomyocytes publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.118.313472 contributor: fullname: Tu – volume: 25 start-page: 1136 year: 2007 ident: 10.1016/j.celrep.2022.111146_bib85 article-title: Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach publication-title: Stem Cell. doi: 10.1634/stemcells.2006-0466 contributor: fullname: Sartiani – volume: 120 start-page: 1487 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib106 article-title: Engineering cardiac muscle tissue: a maturating field of research publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.117.310738 contributor: fullname: Weinberger – volume: 499 start-page: 611 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib24 article-title: Biophysical study of human induced Pluripotent Stem Cell-Derived cardiomyocyte structural maturation during long-term culture publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2018.03.198 contributor: fullname: Dias – volume: 111 start-page: 18126 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib108 article-title: Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1409525111 contributor: fullname: Wrighton – volume: 41 start-page: 83 year: 2003 ident: 10.1016/j.celrep.2022.111146_bib23 article-title: Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertensive heart disease publication-title: Hypertension doi: 10.1161/01.HYP.0000047668.48494.39 contributor: fullname: de las Fuentes – volume: 9 start-page: 421 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib83 article-title: Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis publication-title: Nat. Protoc. doi: 10.1038/nprot.2014.018 contributor: fullname: Salabei – volume: 4 start-page: 3887 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib77 article-title: Simultaneous quantification of mitochondrial DNA copy number and deletion ratio: a multiplex real-time PCR assay publication-title: Sci. Rep. doi: 10.1038/srep03887 contributor: fullname: Phillips – volume: 8 start-page: 567842 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib56 article-title: Scalable biomimetic coaxial aligned nanofiber cardiac patch: a potential model for "clinical trials in a dish publication-title: Front. Bioeng. Biotechnol. doi: 10.3389/fbioe.2020.567842 contributor: fullname: Kumar – start-page: 51873 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib51 article-title: A novel method for localizing reporter fluorescent beads near the cell culture surface for traction force microscopy publication-title: J. Vis. Exp. contributor: fullname: Knoll – volume: 53 start-page: 7412 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib93 article-title: Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering publication-title: Chem. Commun. doi: 10.1039/C7CC01988B contributor: fullname: Smith – volume: 13 start-page: 1705 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib103 article-title: Transcriptional landscape of cardiomyocyte maturation publication-title: Cell Rep. doi: 10.1016/j.celrep.2015.10.032 contributor: fullname: Uosaki – volume: 90 start-page: 194 year: 2011 ident: 10.1016/j.celrep.2022.111146_bib53 article-title: Glucose metabolism and cardiac hypertrophy publication-title: Cardiovasc. Res. doi: 10.1093/cvr/cvr071 contributor: fullname: Kolwicz – volume: 4 start-page: 1019 year: 2012 ident: 10.1016/j.celrep.2022.111146_bib49 article-title: Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration publication-title: Integr. Biol. doi: 10.1039/c2ib20067h contributor: fullname: Kim – volume: 36 start-page: 240 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib6 article-title: Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors publication-title: Cell. Signal. doi: 10.1016/j.cellsig.2017.04.010 contributor: fullname: Archer – volume: 102 start-page: 15545 year: 2005 ident: 10.1016/j.celrep.2022.111146_bib96 article-title: Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.0506580102 contributor: fullname: Subramanian – volume: 415 start-page: 198 year: 2002 ident: 10.1016/j.celrep.2022.111146_bib11 article-title: Cardiac excitation-contraction coupling publication-title: Nature doi: 10.1038/415198a contributor: fullname: Bers – volume: 253 start-page: 120060 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib97 article-title: Efficient differentiation of human pluripotent stem cells into cardiomyocytes on cell sorting thermoresponsive surface publication-title: Biomaterials doi: 10.1016/j.biomaterials.2020.120060 contributor: fullname: Sung – volume: 26 start-page: 105 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib60 article-title: Porous nanofibrous poly(L-lactic acid) scaffolds supporting cardiovascular progenitor cells for cardiac tissue engineering publication-title: Acta Biomater. doi: 10.1016/j.actbio.2015.08.017 contributor: fullname: Liu – volume: 134 start-page: 1557 year: 2016 ident: 10.1016/j.celrep.2022.111146_bib81 article-title: Mechanical stress conditioning and electrical stimulation promote contractility and force maturation of induced pluripotent stem cell-derived human cardiac tissue publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.114.014998 contributor: fullname: Ruan – volume: 117 start-page: 80 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib45 article-title: Human induced pluripotent stem cell-derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.117.305365 contributor: fullname: Karakikes – volume: 10335 start-page: 263 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib3 article-title: A fast prize-collecting steiner forest algorithm for functional analyses in biological networks publication-title: Lect. Notes Comput. Sc. doi: 10.1007/978-3-319-59776-8_22 contributor: fullname: Akhmedov – volume: 5 start-page: 553 year: 2008 ident: 10.1016/j.celrep.2022.111146_bib33 article-title: Real-time imaging of the intracellular glutathione redox potential publication-title: Nat. Methods doi: 10.1038/nmeth.1212 contributor: fullname: Gutscher – volume: 61 start-page: 473 year: 2013 ident: 10.1016/j.celrep.2022.111146_bib67 article-title: Redox signaling in cardiovascular health and disease publication-title: Free Radic. Biol. Med. doi: 10.1016/j.freeradbiomed.2013.04.001 contributor: fullname: Madamanchi – volume: 266 start-page: 22678 year: 1991 ident: 10.1016/j.celrep.2022.111146_bib100 article-title: A MyoD1-independent muscle-specific enhancer controls the expression of the beta-myosin heavy chain gene in skeletal and cardiac muscle cells publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(18)54623-8 contributor: fullname: Thompson – volume: 556 start-page: 239 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib79 article-title: Advanced maturation of human cardiac tissue grown from pluripotent stem cells publication-title: Nature doi: 10.1038/s41586-018-0016-3 contributor: fullname: Ronaldson-Bouchard – volume: 46 start-page: D661 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib92 article-title: WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkx1064 contributor: fullname: Slenter – volume: 34 start-page: D535 year: 2006 ident: 10.1016/j.celrep.2022.111146_bib95 article-title: BioGRID: a general repository for interaction datasets publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkj109 contributor: fullname: Stark – volume: 2 start-page: 150063 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib20 article-title: A resource of ribosomal RNA-depleted RNA-Seq data from different normal adult and fetal human tissues publication-title: Sci. Data doi: 10.1038/sdata.2015.63 contributor: fullname: Choy – volume: 297 start-page: C152 year: 2009 ident: 10.1016/j.celrep.2022.111146_bib59 article-title: Facilitated maturation of Ca2+ handling properties of human embryonic stem cell-derived cardiomyocytes by calsequestrin expression publication-title: Am. J. Physiol. Cell Physiol. doi: 10.1152/ajpcell.00060.2009 contributor: fullname: Liu – volume: 564 start-page: 114 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib68 article-title: Mechanosignalling via integrins directs fate decisions of pancreatic progenitors publication-title: Nature doi: 10.1038/s41586-018-0762-2 contributor: fullname: Mamidi – volume: 6 start-page: ra10 year: 2013 ident: 10.1016/j.celrep.2022.111146_bib38 article-title: A nontranscriptional role for HIF-1alpha as a direct inhibitor of DNA replication publication-title: Sci. Signal. doi: 10.1126/scisignal.2003417 contributor: fullname: Hubbi – volume: 137 start-page: 1407 year: 2010 ident: 10.1016/j.celrep.2022.111146_bib69 article-title: Mechanical control of tissue and organ development publication-title: Development doi: 10.1242/dev.024166 contributor: fullname: Mammoto – volume: 8 start-page: 621644 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib91 article-title: Bearing my heart: the role of extracellular matrix on cardiac development, homeostasis, and injury response publication-title: Front. Cell Dev. Biol. doi: 10.3389/fcell.2020.621644 contributor: fullname: Silva – volume: 114 start-page: 511 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib109 article-title: Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.114.300558 contributor: fullname: Yang – volume: 7 start-page: 8590 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib21 article-title: Distinct carbon sources affect structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells publication-title: Sci. Rep. doi: 10.1038/s41598-017-08713-4 contributor: fullname: Correia – volume: 24 start-page: 669 year: 1992 ident: 10.1016/j.celrep.2022.111146_bib9 article-title: Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man publication-title: J. Mol. Cell. Cardiol. doi: 10.1016/0022-2828(92)93381-S contributor: fullname: Barth – start-page: 2173 year: 2010 ident: 10.1016/j.celrep.2022.111146_bib5 article-title: Preparation of complaint matrices for quantifying cellular contraction publication-title: J. Vis. Exp. contributor: fullname: Aratyn-Schaus – volume: 8 start-page: 21923 year: 2016 ident: 10.1016/j.celrep.2022.111146_bib15 article-title: Nanotopography-induced structural anisotropy and sarcomere development in human cardiomyocytes derived from induced pluripotent stem cells publication-title: ACS Appl. Mater. Interfaces doi: 10.1021/acsami.5b11671 contributor: fullname: Carson – volume: 106 start-page: 857 year: 2000 ident: 10.1016/j.celrep.2022.111146_bib50 article-title: Disruption of the myocardial extracellular matrix leads to cardiac dysfunction publication-title: J. Clin. Invest. doi: 10.1172/JCI8040 contributor: fullname: Kim – volume: 111 start-page: 1091 year: 2012 ident: 10.1016/j.celrep.2022.111146_bib13 article-title: Redox signaling in cardiac physiology and pathology publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.111.255216 contributor: fullname: Burgoyne – volume: 20 start-page: 1896 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib110 article-title: Electrospun PLGA fibers incorporated with functionalized biomolecules for cardiac tissue engineering publication-title: Tissue Eng. Part A doi: 10.1089/ten.tea.2013.0008 contributor: fullname: Yu – volume: 94 start-page: 207 year: 2008 ident: 10.1016/j.celrep.2022.111146_bib82 article-title: High resolution traction force microscopy based on experimental and computational advances publication-title: Biophys. J. doi: 10.1529/biophysj.107.113670 contributor: fullname: Sabass – volume: 15 start-page: 1108 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib44 article-title: Fast, in vivo voltage imaging using a red fluorescent indicator publication-title: Nat. Methods doi: 10.1038/s41592-018-0188-7 contributor: fullname: Kannan – volume: 56 start-page: 130 year: 2010 ident: 10.1016/j.celrep.2022.111146_bib62 article-title: Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation publication-title: J. Cardiovasc. Pharmacol. doi: 10.1097/FJC.0b013e3181e74a14 contributor: fullname: Lopaschuk – volume: 123 start-page: 1066 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib37 article-title: Metabolic maturation of human pluripotent stem cell-derived cardiomyocytes by inhibition of HIF1alpha and LDHA publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.118.313249 contributor: fullname: Hu – volume: 8 start-page: 178 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib2 article-title: A brief review of current maturation methods for human induced pluripotent stem cells-derived cardiomyocytes publication-title: Front. Cell Dev. Biol. doi: 10.3389/fcell.2020.00178 contributor: fullname: Ahmed – volume: 374 start-page: 20180215 year: 2019 ident: 10.1016/j.celrep.2022.111146_bib7 article-title: Tissue mechanics, an important regulator of development and disease publication-title: Philos. Trans. R. Soc. Lond. B Biol. Sci. doi: 10.1098/rstb.2018.0215 contributor: fullname: Ayad – volume: 59 start-page: 413 year: 1993 ident: 10.1016/j.celrep.2022.111146_bib12 article-title: A note on the prize collecting traveling salesman problem publication-title: Math. Program. doi: 10.1007/BF01581256 contributor: fullname: Bienstock – volume: 1711 start-page: 13 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib46 article-title: Discovering altered regulation and signaling through network-based integration of transcriptomic, epigenomic and proteomic tumor data publication-title: Methods Mol. Biol. doi: 10.1007/978-1-4939-7493-1_2 contributor: fullname: Kedaigle – volume: 32 start-page: 107925 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib27 article-title: Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes publication-title: Cell Rep. doi: 10.1016/j.celrep.2020.107925 contributor: fullname: Feyen – volume: 50 start-page: 777 year: 2011 ident: 10.1016/j.celrep.2022.111146_bib84 article-title: Redox signaling in cardiac myocytes publication-title: Free Radic. Biol. Med. doi: 10.1016/j.freeradbiomed.2011.01.003 contributor: fullname: Santos – volume: 21 start-page: 469 year: 2011 ident: 10.1016/j.celrep.2022.111146_bib36 article-title: The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation publication-title: Dev. Cell doi: 10.1016/j.devcel.2011.08.008 contributor: fullname: Hom – volume: 67 start-page: 104891 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib90 article-title: Evaluation of in vitro models of stem cell-derived cardiomyocytes to screen for potential cardiotoxicity of chemicals publication-title: Toxicol. Vitro doi: 10.1016/j.tiv.2020.104891 contributor: fullname: Shi – volume: 18 start-page: 571 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib18 article-title: Neonatal transplantation confers maturation of PSC-derived cardiomyocytes conducive to modeling cardiomyopathy publication-title: Cell Rep. doi: 10.1016/j.celrep.2016.12.040 contributor: fullname: Cho – volume: 16 start-page: 1031 year: 1998 ident: 10.1016/j.celrep.2022.111146_bib80 article-title: Pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans publication-title: J. Hypertens. doi: 10.1097/00004872-199816070-00018 contributor: fullname: Rossi – volume: 298 start-page: 489 year: 1998 ident: 10.1016/j.celrep.2022.111146_bib105 article-title: Preparation of a flexible, porous polyacrylamide substrate for mechanical studies of cultured cells publication-title: Methods Enzymol. doi: 10.1016/S0076-6879(98)98041-7 contributor: fullname: Wang – volume: 10 start-page: e0126338 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib48 article-title: Evaluation of changes in morphology and function of human induced pluripotent stem cell derived cardiomyocytes (HiPSC-CMs) cultured on an aligned-nanofiber cardiac patch publication-title: PLoS One doi: 10.1371/journal.pone.0126338 contributor: fullname: Khan – volume: 2 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib99 article-title: PIVlab -towards user-friendly, affordable and accurate digital particle image velocimetry in MATLAB publication-title: J. Open Res. Software contributor: fullname: Thielicke – volume: 13 start-page: 621 year: 2010 ident: 10.1016/j.celrep.2022.111146_bib72 article-title: Fluorescent protein-based redox probes publication-title: Antioxid. Redox Signal. doi: 10.1089/ars.2009.2948 contributor: fullname: Meyer – volume: 22 start-page: 1991 year: 2013 ident: 10.1016/j.celrep.2022.111146_bib65 article-title: Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells publication-title: Stem Cells Dev. doi: 10.1089/scd.2012.0490 contributor: fullname: Lundy – volume: 7 start-page: 2056 year: 2012 ident: 10.1016/j.celrep.2022.111146_bib28 article-title: Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior publication-title: Nat. Protoc. doi: 10.1038/nprot.2012.127 contributor: fullname: Fischer – volume: 75 start-page: 779 year: 2012 ident: 10.1016/j.celrep.2022.111146_bib41 article-title: Single action potentials and subthreshold electrical events imaged in neurons with a fluorescent protein voltage probe publication-title: Neuron doi: 10.1016/j.neuron.2012.06.040 contributor: fullname: Jin – volume: 7 start-page: 104 year: 2008 ident: 10.1016/j.celrep.2022.111146_bib87 article-title: Conserved metabolic regulatory functions of sirtuins publication-title: Cell Metab. doi: 10.1016/j.cmet.2007.11.006 contributor: fullname: Schwer – volume: 117 start-page: 995 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib26 article-title: Matrigel mattress: a method for the generation of single contracting human-induced pluripotent stem cell-derived cardiomyocytes publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.115.307580 contributor: fullname: Feaster – volume: 126 start-page: 1086 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib32 article-title: Cardiomyocyte maturation: new phase in development publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.119.315862 contributor: fullname: Guo – volume: 32 start-page: 1999 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib54 article-title: Concise review: mechanotransduction via p190RhoGAP regulates a switch between cardiomyogenic and endothelial lineages in adult cardiac progenitors publication-title: Stem Cell. doi: 10.1002/stem.1700 contributor: fullname: Kshitiz – volume: 85 start-page: 1093 year: 2005 ident: 10.1016/j.celrep.2022.111146_bib94 article-title: Myocardial substrate metabolism in the normal and failing heart publication-title: Physiol. Rev. doi: 10.1152/physrev.00006.2004 contributor: fullname: Stanley – volume: 43 start-page: D1057 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib39 article-title: The Goa database: gene Ontology annotation updates for 2015 publication-title: Nucleic Acids Res. doi: 10.1093/nar/gku1113 contributor: fullname: Huntley – volume: 8 start-page: 1763 year: 2013 ident: 10.1016/j.celrep.2022.111146_bib22 article-title: Poly(epsilon-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells publication-title: Nanomedicine (Lond) doi: 10.2217/nnm.12.204 contributor: fullname: Crowder – volume: 18 start-page: 728 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib104 article-title: Mechanical forces direct stem cell behaviour in development and regeneration publication-title: Nat. Rev. Mol. Cell Biol. doi: 10.1038/nrm.2017.108 contributor: fullname: Vining – volume: 5 start-page: 196 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib4 article-title: Glutathione: new roles in redox signaling for an old antioxidant publication-title: Front. Pharmacol. doi: 10.3389/fphar.2014.00196 contributor: fullname: Aquilano – volume: 5 start-page: ra41 year: 2012 ident: 10.1016/j.celrep.2022.111146_bib55 article-title: Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors publication-title: Sci. Signal. doi: 10.1126/scisignal.2003002 contributor: fullname: Kshitiz – volume: 9 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib52 article-title: gprofiler2 -- an R Package for Gene List Functional Enrichment Analysis and Namespace Conversion Toolset g:Profiler publication-title: F1000Res. doi: 10.12688/f1000research.24956.2 contributor: fullname: Kolberg – volume: 5 start-page: 95 year: 1997 ident: 10.1016/j.celrep.2022.111146_bib16 article-title: Structure and function of myocardial fibrillar collagen publication-title: Technol. Health Care doi: 10.3233/THC-1997-51-209 contributor: fullname: Caulfield – volume: 81 start-page: 412 year: 2009 ident: 10.1016/j.celrep.2022.111146_bib40 article-title: Energy metabolism in heart failure and remodelling publication-title: Cardiovasc. Res. doi: 10.1093/cvr/cvn301 contributor: fullname: Ingwall – volume: 121 start-page: 749 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib70 article-title: Hypertrophic cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.117.311059 contributor: fullname: Marian – volume: 125 start-page: e75 year: 2019 ident: 10.1016/j.celrep.2022.111146_bib30 article-title: Use of human induced pluripotent stem cell-derived cardiomyocytes in preclinical cancer drug cardiotoxicity testing: a scientific statement from the American heart association publication-title: Circ. Res. doi: 10.1161/RES.0000000000000291 contributor: fullname: Gintant – volume: 11 start-page: 855 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib14 article-title: Chemically defined generation of human cardiomyocytes publication-title: Nat. Methods doi: 10.1038/nmeth.2999 contributor: fullname: Burridge – volume: 142 start-page: 1448 year: 2020 ident: 10.1016/j.celrep.2022.111146_bib71 article-title: High-resolution transcriptomic profiling of the heart during chronic stress reveals cellular drivers of cardiac fibrosis and hypertrophy publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.119.045115 contributor: fullname: McLellan – volume: 33 start-page: 4327 year: 2012 ident: 10.1016/j.celrep.2022.111146_bib76 article-title: The functional properties of nephronectin: an adhesion molecule for cardiac tissue engineering publication-title: Biomaterials doi: 10.1016/j.biomaterials.2012.03.021 contributor: fullname: Patra – volume: 27 start-page: 441 year: 2011 ident: 10.1016/j.celrep.2022.111146_bib66 article-title: Aerobic glycolysis: meeting the metabolic requirements of cell proliferation publication-title: Annu. Rev. Cell Dev. Biol. doi: 10.1146/annurev-cellbio-092910-154237 contributor: fullname: Lunt – volume: 589 start-page: 4413 year: 2011 ident: 10.1016/j.celrep.2022.111146_bib78 article-title: Mitochondria: isolation, structure and function publication-title: J. Physiol. doi: 10.1113/jphysiol.2011.212712 contributor: fullname: Picard – volume: 8 start-page: 1825 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib89 article-title: Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues publication-title: Nat. Commun. doi: 10.1038/s41467-017-01946-x contributor: fullname: Shadrin – volume: 12 start-page: 127 year: 2013 ident: 10.1016/j.celrep.2022.111146_bib101 article-title: Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes publication-title: Cell Stem Cell doi: 10.1016/j.stem.2012.09.013 contributor: fullname: Tohyama – volume: 113 start-page: 709 year: 2013 ident: 10.1016/j.celrep.2022.111146_bib25 article-title: Cardiac metabolism in heart failure: implications beyond ATP production publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.113.300376 contributor: fullname: Doenst – volume: 23 start-page: 2489 year: 2019 ident: 10.1016/j.celrep.2022.111146_bib111 article-title: JS-K induces reactive oxygen species-dependent anti-cancer effects by targeting mitochondria respiratory chain complexes in gastric cancer publication-title: J. Cell Mol. Med. doi: 10.1111/jcmm.14122 contributor: fullname: Zhao – volume: 116 start-page: 341 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib73 article-title: Molecular regulation of cardiomyocyte differentiation publication-title: Circ. Res. doi: 10.1161/CIRCRESAHA.116.302752 contributor: fullname: Paige – volume: 32 start-page: D258 year: 2004 ident: 10.1016/j.celrep.2022.111146_bib34 article-title: The Gene Ontology (GO) database and informatics resource publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkh036 contributor: fullname: Harris – volume: 138 start-page: 4499 year: 2011 ident: 10.1016/j.celrep.2022.111146_bib75 article-title: Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish publication-title: Development doi: 10.1242/dev.067454 contributor: fullname: Patra – volume: 5 start-page: 18705 year: 2015 ident: 10.1016/j.celrep.2022.111146_bib42 article-title: An integrated statistical model for enhanced murine cardiomyocyte differentiation via optimized engagement of 3D extracellular matrices publication-title: Sci. Rep. doi: 10.1038/srep18705 contributor: fullname: Jung – volume: 96 start-page: 253 year: 2016 ident: 10.1016/j.celrep.2022.111146_bib58 article-title: The electrophysiological development of cardiomyocytes publication-title: Adv. Drug Deliv. Rev. doi: 10.1016/j.addr.2015.12.023 contributor: fullname: Liu – volume: 17 start-page: 48 year: 2000 ident: 10.1016/j.celrep.2022.111146_bib107 article-title: The Kyoto encyclopedia of genes and genomes--KEGG publication-title: Yeast contributor: fullname: Wixon – volume: 5 start-page: 17 year: 2014 ident: 10.1016/j.celrep.2022.111146_bib47 article-title: Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes publication-title: Stem Cell Res. Ther. doi: 10.1186/scrt406 contributor: fullname: Keung – volume: 23 start-page: 586 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib29 article-title: Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation publication-title: Cell Stem Cell doi: 10.1016/j.stem.2018.09.009 contributor: fullname: Friedman – volume: 7 start-page: 3566 year: 2019 ident: 10.1016/j.celrep.2022.111146_bib86 article-title: Native cardiac environment and its impact on engineering cardiac tissue publication-title: Biomater. Sci. doi: 10.1039/C8BM01348A contributor: fullname: Schwach – volume: 1863 start-page: 1829 year: 2016 ident: 10.1016/j.celrep.2022.111146_bib10 article-title: Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbamcr.2015.11.005 contributor: fullname: Bedada – volume: 90 start-page: 207 year: 2010 ident: 10.1016/j.celrep.2022.111146_bib63 article-title: Myocardial fatty acid metabolism in health and disease publication-title: Physiol. Rev. doi: 10.1152/physrev.00015.2009 contributor: fullname: Lopaschuk – volume: 9 start-page: 110 year: 2016 ident: 10.1016/j.celrep.2022.111146_bib35 article-title: Systematic characterization of long noncoding RNAs reveals the contrasting coordination of cis- and trans-molecular regulation in human fetal and adult hearts publication-title: Circ. Cardiovasc. Genet. doi: 10.1161/CIRCGENETICS.115.001264 contributor: fullname: He – volume: 2018 start-page: 5835072 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib64 article-title: Reactive oxygen species from NADPH oxidase and mitochondria participate in the proliferation of aortic smooth muscle cells from a model of metabolic syndrome publication-title: Oxid. Med. Cell. Longev. doi: 10.1155/2018/5835072 contributor: fullname: López-Acosta – volume: 499 start-page: 295 year: 2013 ident: 10.1016/j.celrep.2022.111146_bib17 article-title: Ultrasensitive fluorescent proteins for imaging neuronal activity publication-title: Nature doi: 10.1038/nature12354 contributor: fullname: Chen – volume: 108 start-page: 12920 year: 2011 ident: 10.1016/j.celrep.2022.111146_bib61 article-title: Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1107332108 contributor: fullname: Liu – volume: 2 start-page: 543 year: 2017 ident: 10.1016/j.celrep.2022.111146_bib1 article-title: Cardiosphere-derived cells demonstrate metabolic flexibility that is influenced by adhesion status publication-title: JACC. Basic Transl. Sci. doi: 10.1016/j.jacbts.2017.03.016 contributor: fullname: Afzal – volume: 5 start-page: 887 year: 2019 ident: 10.1016/j.celrep.2022.111146_bib43 article-title: Optimizing blended collagen-fibrin hydrogels for cardiac tissue engineering with human iPSC-derived cardiomyocytes publication-title: ACS Biomater. Sci. Eng. doi: 10.1021/acsbiomaterials.8b01112 contributor: fullname: Kaiser – volume: 183 start-page: 127 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib31 article-title: The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: special focus on Ik1 publication-title: Pharmacol. Ther. doi: 10.1016/j.pharmthera.2017.10.001 contributor: fullname: Goversen – volume: 27 start-page: 1047 year: 2018 ident: 10.1016/j.celrep.2022.111146_bib57 article-title: The impact of in vitro cell culture duration on the maturation of human cardiomyocytes derived from induced pluripotent stem cells of myogenic origin publication-title: Cell Transplant. doi: 10.1177/0963689718779346 contributor: fullname: Lewandowski |
SSID | ssj0000601194 |
Score | 2.4502177 |
Snippet | The vast potential of human induced pluripotent stem-cell-derived cardiomyocytes (hiPSC-CMs) in preclinical models of cardiac pathologies, precision medicine,... |
SourceID | doaj proquest crossref pubmed elsevier |
SourceType | Open Website Aggregation Database Index Database Publisher |
StartPage | 111146 |
SubjectTerms | Adult adult heart like cardiac maturation cardiac mimetic cardiac ultrastructure Cell Differentiation - physiology Cells, Cultured CP: cell biology CP: Developmental biology hiPSC derived cardiomyocytes Humans Hypertrophy - metabolism Induced Pluripotent Stem Cells - metabolism metabolic maturation Myocytes, Cardiac - metabolism oxidative phosphorylation pathological hypertrophy redox handling substrate topography |
SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Li9swEBZlodBL6bvpCxV6NbUlWVaOu0uXpdCeurA3IY1GkJI4JZvA5tpf3hkpXtJD2UuPNn4IfeOZb6TxN0J86qKlOKdCY2zQjYkOmrlNtiFfOTgIRBkCJ4rfvtvLK_P1ur8-avXFNWFVHrhO3Oc2xdyGQN-k0gagD8FGZ3UwzlJsy1UJtOuPkqnqg1nLjLeUleKaLWWG6b-5UtwFuNwgy1UqVZwG89-juFTk-_8KT_-inyUMXTwRjw_8UZ7WcT8VD3B8Jh7WjpL75-L3eUEc5G653YQqDrvboFyMvKOOSa5Ykv-WjhNheiOnEgC5wi2Zw3IBMoxJcrSri4R8w65aiVxnOfVTIb9AVFWWDn8SSk3rar-GPRHXF-Lq4suP88vm0GahATOYbQPOYI4actumDKnvXasDAkLfYkrZssidtoi2i0D5ckJs561LMQZlkhm0filOxvWIr4WcBxchZyKBifLOro2K6IJz0Dl0vYl6Jpppkv2vqqbhpzKzn76C4hkUX0GZiTNG4u5a1sIuJ8hC_MFC_H0WMhPDhKM_0IpKF-hRi3te_3GC3dNXx1spYcT17sYr1hRi5Ro1E6-qPdwNUvdzIsFd9-Z_DP6teMQD4tVkZd-JE7IbfE80aBs_FIv_AzPWBhk priority: 102 providerName: Directory of Open Access Journals – databaseName: ScienceDirect Free and Delayed Access Journal dbid: IXB link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LaxsxEBYhUOil9F33hQq9CmslrVY-NqYhFNpLG_BN6LVli70bHBvqa355ZqRd0xxCIUcJaSU0szOfpNE3hHyuvAY_JxxT2kmmvAlsoaNmYCsbExxABocbxe8_9MWl-raqVydkOb2FwbDK0fYXm56t9VgzH1dzftV1858C9i7gnRohMo_aCuwwcnviI77V2fGcBflGqpwPEdsz7DC9oMthXiGttwmJK4XI5gOR8D8eKhP533FU9wHR7JDOn5InI5KkX8pkn5GT1D8nj0puycMLcrPMsg90v95tXaGJ3W8T7Xq8W0-RbpCc_y-UI0j3mk7BAHSTdqAY6y5Q10eKfq8cF2KHfdEXOrR0yqwCFgJAK825_mjI0a2bwxAOAGFfksvzr7-WF2xMuMCCatSOBaNS62VoOY9tiHVtuHQppFDzFGOrke5O6pR05QPsnGNKfMFN9N4JFVUj5Sty2g99ekPowhkf2hbgYIQdaMW9AOBgTKhMMrXyckbYtMj2qvBq2Cng7I8tQrEoFFuEMiNnKIljW2TFzhXD9rcd1cLy6FvuHNhvIVUItXPaGy2dMhpwUKtmpJnkaO8oGXyq-8_wnyaxW_j_8FLF9WnYX1uB7ELIYSNm5HXRh-MkZb0AOFxVbx887jvyGEt4mCz0e3IKypI-AAra-Y9ZzW8BfZkHRg priority: 102 providerName: Elsevier |
Title | Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes |
URI | https://dx.doi.org/10.1016/j.celrep.2022.111146 https://www.ncbi.nlm.nih.gov/pubmed/35905711 https://search.proquest.com/docview/2696861232 https://doaj.org/article/0dbf0aa911234cc5aa6b863a486822f4 |
Volume | 40 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3Pi9QwFA7riuBF_O2sukTwWkmTNJM5iLiLyyqsJwfmFpKXREZmWu3MwM51_3JfknZlwUUvhZamLfle3vtekn6PkLe1UxjnuK2ksqKSTkM1U15V6CunGixSBpsSxYuv6nwuvyyaxQEZa7YOHbj5a2qX6knN-9W7y1_7Dzjg3__ZqwVh1YekPsl59gFS3SF3uRQy2fzFQPiLb04aZ3L8h-6WxjdiVJbyvxGqbqOiOSSdPSQPBi5JPxbwH5GD0D4m90p1yf0TcnWa0Qe6W217W4Rid32gyzatrgdP10me_xLPPeK7oeN2ALoOWzSN1RKobT1Nka9MGKYGu2IxtIt0rK2CPgJpK83V_ijk_a3rfQd7JLFPyfzs07fT82oouVCBnMptBVqG6ARExnwE3zSaCRsgQMOC91ElwTuhQlC1A8ydfQhsxrR3znLp5VSIZ-Sw7drwgtCZ1Q5iRELoMQetmeNIHbSGWgfdSCcmpBo72fwsyhpm3HL2wxRQTALFFFAm5CQhcX1v0sXOF7r-uxmGmWHeRWYtenAuJEBjrXJaCSu1QiYU5YRMRxzNQDEKdcBHLf_x-jcj7AZHYFpWsW3odhvDk75QUrHhE_K82MP1R4pmhoS4ro_-o_VLcj-9L00cc_WKHKJZhNfIeLbuOM8U4PHz4uQ4G_RvRgUEoQ |
link.rule.ids | 315,786,790,870,2115,2236,3525,24346,27957,27958,45909 |
linkProvider | Scholars Portal |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELZKEYIL4s3yNBLXaB3bcbxHuqLaQtsLrbQ3y6-goN1std2Vutf-cmbsZEUPCIljHk4sz5eZz_bkG0I-l05BnOO2kMqKQjrti4kKqgBfWWtvgTJYnCienavZpfw2r-YHZDr8C4Nplb3vzz49eev-zLgfzfFV245_cJi7QHSqOU86avN75L6sJgyhfTI_2i-0oOBImQoiYoMCWwy_0KU8Lx8X64jKlZwn_4FU-I8QlZT870SqvzHRFJGOn5DHPZWkX3Jvn5KD2D0jD3Jxyd1zcjtNxvd0u9isbdaJ3a4jbTvcXI-BLlGd_waOA5j3mg7ZAHQZN4CMReup7QLFwJfXC7HBNgOGrho6lFYBFwGslaZif9Sn9NblbuV3wGFfkMvjrxfTWdFXXCi8rOWm8FrGxgnfMBYaH6pKM2Gjj75iMYRGod6dUDGq0nmYOocY2YTp4JzlMshaiJfksFt18TWhE6udbxrggwGmoCVzHJiD1r7UUVfSiREphkE2V1lYwwwZZ79MNopBo5hslBE5Qkvs70VZ7HRitf5pelwYFlzDrAUHzoX0vrJWOa2ElVoBEWrkiNSDHc0dlMGj2n-8_tNgdgMfIO6q2C6utteGo7wQitjwEXmV8bDvpAA8VnVZvvnv934kD2cXZ6fm9OT8-1vyCK_gyjJX78ghACe-B0q0cR8S5H8DzlYKbQ |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cardiac+ultrastructure+inspired+matrix+induces+advanced+metabolic+and+functional+maturation+of+differentiated+human+cardiomyocytes&rft.jtitle=Cell+reports+%28Cambridge%29&rft.au=Afzal%2C+Junaid&rft.au=Liu%2C+Yamin&rft.au=Du%2C+Wenqiang&rft.au=Suhail%2C+Yasir&rft.date=2022-07-26&rft.eissn=2211-1247&rft.volume=40&rft.issue=4&rft.spage=111146&rft.epage=111146&rft_id=info:doi/10.1016%2Fj.celrep.2022.111146&rft.externalDBID=NO_FULL_TEXT |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2211-1247&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2211-1247&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2211-1247&client=summon |