TCA cycle rewiring fosters metabolic adaptation to oxygen restriction in skeletal muscle from rodents and humans - Capitanio, Daniele; Fania, Chiara; Torretta, Enrica; Viganò, Agnese; Moriggi, Manuela; Bravatà, Valentina; Caretti, Anna; Levett, Denny Z. H.; Grocott, Michael P. W.; Samaja, Michele; Cerretelli, Paolo; Gelfi, Cecilia (Scientific reports, 2017)
Keywords: 38; 38/77; 631/45/475/2290; 692/4017; 82; 82/1; 82/29; 82/58; Adaptation, Physiological; Animals; Autophagy; Basic Helix-Loop-Helix Transcription Factors - genetics; Basic Helix-Loop-Helix Transcription Factors - metabolism; Citric Acid Cycle; Energy demand; Energy Metabolism; Enzymatic activity; Gene Expression; Glutamine; Hexosamines - metabolism; High-altitude environments; Homeostasis; Human subjects; Humanities and Social Sciences; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit - genetics; Hypoxia-Inducible Factor 1, alpha Subunit - metabolism; Metabolic Networks and Pathways; Metabolism; Models, Biological; multidisciplinary; Muscle, Skeletal - metabolism; Musculoskeletal system; Oxygen - metabolism; Proteome; Proteomics; Proteomics - methods; Rodentia; Rodents; Science; Science (multidisciplinary); Signal Transduction; Skeletal muscle; Time Factors; Tricarboxylic acid cycle