Host and gut bacteria share metabolic pathways for anti-cancer drug metabolism - Spanogiannopoulos, Peter; Kyaw, Than S.; Guthrie, Ben G. H.; Bradley, Patrick H.; Lee, Joyce V.; Melamed, Jonathan; Malig, Ysabella Noelle Amora; Lam, Kathy N.; Gempis, Daryll; Sandy, Moriah; Kidder, Wesley; Van Blarigan, Erin L.; et al. (Nature microbiology, 2022)
Keywords: 38; 38/91; 45/23; 5-Fluorouracil; 631/326/2565/2134; 631/67/70; 64/60; 692/4017; 82; 82/58; Animals; Antibacterial activity; Antineoplastic Agents - metabolism; Antineoplastic Agents - pharmacology; Antitumor agents; Bacteria - genetics; Bioavailability; Biomedical and Life Sciences; Cancer; Colorectal carcinoma; Drug metabolism; Escherichia coli; Escherichia coli - genetics; Escherichia coli - metabolism; Fluorouracil - metabolism; Fluorouracil - pharmacology; Humans; Infectious Diseases; Intestinal microflora; Life Sciences; Mammalian cells; Mammals; Medical Microbiology; Metabolic Networks and Pathways; Metabolic pathways; Metabolism; Metabolites; Mice; Microbiology; Microbiomes; Parasitology; Virology